Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation

Journal of Biological Chemistry

Volumn 274, Issue 23, 1999, Pages 16168-16173

  Feinmesser, Rachel L ^a   Wicks, Stephen J ^a   Taverner, Claire J ^a   Chantry, Andrew ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); SERINE;

ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL TRANSFORMATION; DNA FLANKING REGION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CYTOPLASM; DOWN REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION;

AMINO ACID SEQUENCE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CYTOPLASM; DOWN-REGULATION; FIBROBLASTS; GLUTATHIONE TRANSFERASE; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; SERINE; SIGNAL TRANSDUCTION;

EID: 0033522642     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.23.16168     Document Type: Article

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