Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle. Gβγ -dependent mitogen-activated protein kinase activation and growth

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7187-7194

  Kuemmerle, John F ^a,b   Murthy, Karnam S ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; INSULIN; MUSCLE; PROTEINS;

PHOSPHORYLATION;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; ADENYLATE CYCLASE; CYCLIC AMP; FORSKOLIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ADENYLATE CYCLASE TOXIN; BORDETELLA VIRULENCE FACTOR; CHROMONE DERIVATIVE; ENZYME INHIBITOR; FLAVONOID; G PROTEIN BETA GAMMA; G-PROTEIN BETA GAMMA; GNAI2 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHOLINE DERIVATIVE; ONCOPROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; INTESTINE MUSCLE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; CELL CULTURE; CELL DIVISION; DOSE RESPONSE; INTESTINE; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; TIME;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; CELL DIVISION; CELLS, CULTURED; CHROMONES; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; FORSKOLIN; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR II; INTESTINES; MAP KINASE SIGNALING SYSTEM; MORPHOLINES; MUSCLE, SMOOTH; PERTUSSIS TOXIN; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR, IGF TYPE 1; RECOMBINANT PROTEINS; TIME FACTORS; VIRULENCE FACTORS, BORDETELLA;

EID: 0035831492     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011145200     Document Type: Article

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