-
1
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
Gilks, W., Abou-Sleiman, P., Gandhi, S., Jain, S., Singleton, A., Lees, A., Shaw, K., Bhatia, K., Bonifati, V., Quinn, N et al. (2005) A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet, 365, 415-416.
-
(2005)
Lancet
, vol.365
, pp. 415-416
-
-
Gilks, W.1
Abou-Sleiman, P.2
Gandhi, S.3
Jain, S.4
Singleton, A.5
Lees, A.6
Shaw, K.7
Bhatia, K.8
Bonifati, V.9
Quinn, N.10
-
2
-
-
0242300619
-
alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton, A.B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R. et al. (2003) alpha-Synuclein locus triplication causes Parkinson's disease. Science, 302, 415-416.
-
(2003)
Science
, vol.302
, pp. 415-416
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
-
3
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
Satake, W., Nakabayashi, Y., Mizuta, I., Hirota, Y., Ito, C., Kubo, M., Kawaguchi, T., Tsunoda, T., Watanabe, M., Takeda, A. et al. (2009) Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat. Genet., 41, 1303-1307.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
Kubo, M.6
Kawaguchi, T.7
Tsunoda, T.8
Watanabe, M.9
Takeda, A.10
-
4
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez, J., Schulte, C., Bras, J., Sharma, M., Gibbs, R., Berg, D., Paisan-Ruiz, C., Lichtner, P., Scholz, S., Hernandez, D. et al. (2009) Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat. Genet., 41, 1308-1312.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.3
Sharma, M.4
Gibbs, R.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.9
Hernandez, D.10
-
5
-
-
77951185469
-
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease
-
Edwards, T.L., Scott, W.K., Almonte, C., Burt, A., Powell, E.H., Beecham, G.W., Wang, L., Zuchner, S., Konidari, I., Wang, G. et al. (2010) Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Ann. Hum. Genet., 74, 97-109.
-
(2010)
Ann. Hum. Genet.
, vol.74
, pp. 97-109
-
-
Edwards, T.L.1
Scott, W.K.2
Almonte, C.3
Burt, A.4
Powell, E.H.5
Beecham, G.W.6
Wang, L.7
Zuchner, S.8
Konidari, I.9
Wang, G.10
-
6
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet., 39, 906-913.
-
(2007)
Nat. Genet.
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
7
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B.N., Donnelly, P. and Marchini, J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
-
(2009)
PLoS Genet.
, vol.5
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
8
-
-
0001241160
-
On Simpson's paradox and the sure thing principle
-
Blyth, C.R. (1972) On Simpson's paradox and the sure thing principle. J. Am. Stat. Assoc., 67, 364-366.
-
(1972)
J. Am. Stat. Assoc.
, vol.67
, pp. 364-366
-
-
Blyth, C.R.1
-
9
-
-
0001745298
-
The interpretation of interaction in contingency tables
-
Simpson, E.H. (1951) The interpretation of interaction in contingency tables. J. Roy. Statist. Soc. (Ser. B), 13, 238-241.
-
(1951)
J. Roy. Statist. Soc. (Ser. B)
, vol.13
, pp. 238-241
-
-
Simpson, E.H.1
-
10
-
-
20144387092
-
Multiple regions of alpha-synuclein are associated with Parkinson's disease
-
Mueller, J., Fuchs, J., Hofer, A., Zimprich, A., Lichtner, P., Illig, T., Berg, D., Wüllner, U., Meitinger, T. and Gasser, T. (2005) Multiple regions of alpha-synuclein are associated with Parkinson's disease. Ann. Neurol., 57, 535-541.
-
(2005)
Ann. Neurol.
, vol.57
, pp. 535-541
-
-
Mueller, J.1
Fuchs, J.2
Hofer, A.3
Zimprich, A.4
Lichtner, P.5
Illig, T.6
Berg, D.7
Wullner, U.8
Meitinger, T.9
Gasser, T.10
-
11
-
-
76349117214
-
The distribution and most recent common ancestor of the 17q21 inversion in humans
-
Donnelly, M.P., Paschou, P., Grigorenko, E., Gurwitz, D., Mehdi, S.Q., Kajuna, S.L., Barta, C., Kungulilo, S., Karoma, N.J., Lu, R.B. et al. (2010) The distribution and most recent common ancestor of the 17q21 inversion in humans. Am. J. Hum. Genet., 86, 161-71.
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 161-171
-
-
Donnelly, M.P.1
Paschou, P.2
Grigorenko, E.3
Gurwitz, D.4
Mehdi, S.Q.5
Kajuna, S.L.6
Barta, C.7
Kungulilo, S.8
Karoma, N.J.9
Lu, R.B.10
-
12
-
-
13944278863
-
A common inversion under selection in Europeans
-
Stefansson, H., Helgason, A., Thorleifsson, G., Steinthorsdottir, V., Masson, G., Barnard, J., Baker, A., Jonasdottir, A., Ingason, A., Gudnadottir, V. et al. (2005) A common inversion under selection in Europeans. Nat. Genet., 37, 129-137.
-
(2005)
Nat. Genet.
, vol.37
, pp. 129-137
-
-
Stefansson, H.1
Helgason, A.2
Thorleifsson, G.3
Steinthorsdottir, V.4
Masson, G.5
Barnard, J.6
Baker, A.7
Jonasdottir, A.8
Ingason, A.9
Gudnadottir, V.10
-
13
-
-
4644372063
-
The tau H2 haplotype is almost exclusively Caucasian in origin
-
Evans, W., Fung, H.C., Steele, J., Eerola, J., Tienari, P., Pittman, A., Silva, R., Myers, A., Vrieze, F.W.-D., Singleton, A. et al. (2004) The tau H2 haplotype is almost exclusively Caucasian in origin. Neurosci. Lett., 369, 183-185.
-
(2004)
Neurosci. Lett.
, vol.369
, pp. 183-185
-
-
Evans, W.1
Fung, H.C.2
Steele, J.3
Eerola, J.4
Tienari, P.5
Pittman, A.6
Silva, R.7
Myers, A.8
Vrieze, F.-D.9
Singleton, A.10
-
14
-
-
77950405093
-
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3 000 shared controls
-
Craddock, N., Hurles, M.E., Cardin, N., Pearson, R.D., Plagnol, V., Robson, S., Vukcevic, D., Barnes, C., Conrad, D.F., Giannoulatou, E. et al. (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464, 713-720.
-
(2010)
Nature
, vol.464
, pp. 713-720
-
-
Craddock, N.1
Hurles, M.E.2
Cardin, N.3
Pearson, R.D.4
Plagnol, V.5
Robson, S.6
Vukcevic, D.7
Barnes, C.8
Conrad, D.F.9
Giannoulatou, E.10
-
15
-
-
3042813452
-
The structure of the tau haplotype in controls and in progressive supranuclear palsy
-
Pittman, A.M., Myers, A.J., Duckworth, J., Bryden, L., Hanson, M., Abou-Sleiman, P., Wood, N.W., Hardy, J., Lees, A. and de Silva, R. (2004) The structure of the tau haplotype in controls and in progressive supranuclear palsy. Hum. Mol. Genet., 13, 1267-1274.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1267-1274
-
-
Pittman, A.M.1
Myers, A.J.2
Duckworth, J.3
Bryden, L.4
Hanson, M.5
Abou-Sleiman, P.6
Wood, N.W.7
Hardy, J.8
Lees, A.9
de Silva, R.10
-
16
-
-
26444608642
-
Genomic architecture of human 17q21 linked to frontotemporal dementia uncovers a highly homologous family of low-copy repeats in the tau region
-
Cruts, M., Rademakers, R., Gijselinck, I., van der Zee, J., Dermaut, B., de Pooter, T., de Rijk, P., Del-Favero, J. and van Broeckhoven, C. (2005) Genomic architecture of human 17q21 linked to frontotemporal dementia uncovers a highly homologous family of low-copy repeats in the tau region. Hum. Mol. Genet., 14, 1753-1762.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1753-1762
-
-
Cruts, M.1
Rademakers, R.2
Gijselinck, I.3
van der Zee, J.4
Dermaut, B.5
de Pooter, T.6
de Rijk, P.7
Del-Favero, J.8
van Broeckhoven, C.9
-
17
-
-
50449104624
-
Evolutionary toggling of the MAPT 17q21.31 inversion region
-
Zody, M.C., Jiang, Z., Fung, H.C., Antonacci, F., Hillier, L.W., Cardone, M.F., Graves, T.A., Kidd, J.M., Cheng, Z., Abouelleil, A. et al. (2008) Evolutionary toggling of the MAPT 17q21.31 inversion region. Nat. Genet., 40, 1076-1083.
-
(2008)
Nat. Genet.
, vol.40
, pp. 1076-1083
-
-
Zody, M.C.1
Jiang, Z.2
Fung, H.C.3
Antonacci, F.4
Hillier, L.W.5
Cardone, M.F.6
Graves, T.A.7
Kidd, J.M.8
Cheng, Z.9
Abouelleil, A.10
-
18
-
-
67650504948
-
Association of MAPT haplotypetagging SNPs with sporadic Parkinson's disease
-
Vandrovcova, J., Pittman, A., Malzer, E., Abou-Sleiman, P., Lees, A., Wood, N. and de Silva, R. (2009) Association of MAPT haplotypetagging SNPs with sporadic Parkinson's disease. Neurobiol. Aging, 30, 1477-1482.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 1477-1482
-
-
Vandrovcova, J.1
Pittman, A.2
Malzer, E.3
Abou-Sleiman, P.4
Lees, A.5
Wood, N.6
de Silva, R.7
-
19
-
-
78649522784
-
Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy
-
(in press)
-
Ezquerra, M., Pastor, P., Gaig, C., Vidal-Taboada, J.M., Cruchaga, C., Munoz, E., Marti, M.J., Valldeoriola, F., Aguilar, M., Calopa, M. et al. (2009) Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy. Neurobiol. Aging (in press).
-
(2009)
Neurobiol. Aging
-
-
Ezquerra, M.1
Pastor, P.2
Gaig, C.3
Vidal-Taboada, J.M.4
Cruchaga, C.5
Munoz, E.6
Marti, M.J.7
Valldeoriola, F.8
Aguilar, M.9
Calopa, M.10
-
20
-
-
33847178181
-
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
-
Myers, A., Pittman, A., Zhao, A., Rohrer, K., Kaleem, M., Marlowe, L., Lees, A., Leung, D., McKeith, I., Perry, R. et al. (2007) The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiol. Dis., 25, 561-570.
-
(2007)
Neurobiol. Dis.
, vol.25
, pp. 561-570
-
-
Myers, A.1
Pittman, A.2
Zhao, A.3
Rohrer, K.4
Kaleem, M.5
Marlowe, L.6
Lees, A.7
Leung, D.8
McKeith, I.9
Perry, R.10
-
21
-
-
77953810149
-
A Bayesian method for detecting and characterizing allelic heterogeneity and boosting signals in genome-wide association studies
-
the Wellcome Trust Case Control Consortium, Donnelly, P. and Marchini, J.
-
Zhan Su, N.C., the Wellcome Trust Case Control Consortium, Donnelly, P. and Marchini, J. (2009) A Bayesian method for detecting and characterizing allelic heterogeneity and boosting signals in genome-wide association studies. Stat. Sci., 24, 430-450.
-
(2009)
Stat. Sci.
, vol.24
, pp. 430-450
-
-
Zhan Su, N.C.1
-
22
-
-
67349166946
-
Detecting gene-gene interactions that underlie human diseases
-
Cordell, H. (2009) Detecting gene-gene interactions that underlie human diseases. Nat. Rev. Genet., 10, 392-404.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 392-404
-
-
Cordell, H.1
-
23
-
-
34147109175
-
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
-
Fuchs, J., Nilsson, C., Kachergus, J., Munz, M., Larsson, E.M., Schule, B., Langston, J.W., Middleton, F.A., Ross, O.A., Hulihan, M. et al. (2007) Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology, 68, 916-922.
-
(2007)
Neurology
, vol.68
, pp. 916-922
-
-
Fuchs, J.1
Nilsson, C.2
Kachergus, J.3
Munz, M.4
Larsson, E.M.5
Schule, B.6
Langston, J.W.7
Middleton, F.A.8
Ross, O.A.9
Hulihan, M.10
-
24
-
-
24644502474
-
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
-
Pittman, A.M., Myers, A.J., Abou-Sleiman, P., Fung, H.C., Kaleem, M., Marlowe, L., Duckworth, J., Leung, D., Williams, D., Kilford, L. et al. (2005) Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J. Med. Genet., 42, 837-846.
-
(2005)
J. Med. Genet.
, vol.42
, pp. 837-846
-
-
Pittman, A.M.1
Myers, A.J.2
Abou-Sleiman, P.3
Fung, H.C.4
Kaleem, M.5
Marlowe, L.6
Duckworth, J.7
Leung, D.8
Williams, D.9
Kilford, L.10
-
25
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447, 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
26
-
-
0026514953
-
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
-
Hughes, A.J., Daniel, S.E., Kilford, L. and Lees, A.J. (1992) Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J. Neurol. Neurosurg. Psychiatry, 55, 181-184.
-
(1992)
J. Neurol. Neurosurg. Psychiatry
, vol.55
, pp. 181-184
-
-
Hughes, A.J.1
Daniel, S.E.2
Kilford, L.3
Lees, A.J.4
-
27
-
-
35748941336
-
A genotype calling algorithm for the Illumina BeadArray platform
-
Teo, Y., Inouye, M., Small, K., Gwilliam, R., Deloukas, P., Kwiatkowski, D. and Clark, T. (2007) A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics, 23, 2741-2746.
-
(2007)
Bioinformatics
, vol.23
, pp. 2741-2746
-
-
Teo, Y.1
Inouye, M.2
Small, K.3
Gwilliam, R.4
Deloukas, P.5
Kwiatkowski, D.6
Clark, T.7
-
28
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M., Bender, D., Maller, J., Sklar, P., de Bakker, P., Daly, M. et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet., 81, 559-575.
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.9
Daly, M.10
-
29
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price, A., Patterson, N., Plenge, R., Weinblatt, M., Shadick, N. and Reich, D. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet., 38, 904-909.
-
(2006)
Nat. Genet.
, vol.38
, pp. 904-909
-
-
Price, A.1
Patterson, N.2
Plenge, R.3
Weinblatt, M.4
Shadick, N.5
Reich, D.6
|