Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

Oncogene

Volumn 30, Issue 45, 2011, Pages 4567-4577

  Lu, Y ^a,d   Muller, M ^a,d   Smith, D ^a   Dutta, B ^a   Komurov, K ^a   Iadevaia, S ^a   Ruths, D ^b   Tseng, J T ^a   Yu, S ^a   Yu, Q ^a   Nakhleh, L ^b   Balazsi, G ^a   Donnelly, J ^c   Schurdak, M ^c   Morgan Lappe, S ^c   Fesik, S ^c,d   Ram, P T ^a,d   Mills, G B ^a,d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Rice University   (United States)

^c ABBOTT LABORATORIES   (United States)

^d VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

AKT; MAPK; proteomics; signaling networks; siRNA

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; TUBERIN;

ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; METABOLIC NETWORKS AND PATHWAYS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEOMICS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 80755132133     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.164     Document Type: Article

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