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Volumn 21, Issue 4, 2008, Pages 191-202

Skin irritation and sensitization: Mechanisms and new approaches for risk assessment - 2. Skin sensitization

Author keywords

Allergic contact dermatitis; Local lymph node assay; Risk assessment

Indexed keywords

HAPTEN;

EID: 47249087716     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000135635     Document Type: Review
Times cited : (73)

References (91)
  • 1
    • 84895316581 scopus 로고    scopus 로고
    • Mechanisms in allergic contact dermatitis
    • Frosch P, Menné T, Lepoittevin J-P eds, Heidelberg, Springer
    • Rustemeyer T, Hoogstraten I, Blomberg BV, Scheper R: Mechanisms in allergic contact dermatitis; in Frosch P, Menné T, Lepoittevin J-P (eds): Contact Dermatitis. Heidelberg, Springer, 2006, pp 11-44.
    • (2006) Contact Dermatitis , pp. 11-44
    • Rustemeyer, T.1    Hoogstraten, I.2    Blomberg, B.V.3    Scheper, R.4
  • 3
    • 0003188912 scopus 로고
    • Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances
    • EEC: EEC Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Off J Eur Commun, 196, 1967, pp 1-98.
    • (1967) Off J Eur Commun , vol.196 , pp. 1-98
    • EEC, E.E.C.1
  • 4
    • 47249123497 scopus 로고    scopus 로고
    • EC: Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off J Eur Union, L 396/1, 2006.
    • EC: Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off J Eur Union, L 396/1, 2006.
  • 5
    • 47249138924 scopus 로고    scopus 로고
    • http://www.unece.org/trans/danger/publi/ghs/ghs_rev00/English/ GHS-PART-3e.pdf.2007.
  • 8
    • 0001267196 scopus 로고
    • Delayed contact hypersensitivity in the guinea pig
    • Buehler EV: Delayed contact hypersensitivity in the guinea pig. Arch Dermatol 1965;91:171-177.
    • (1965) Arch Dermatol , vol.91 , pp. 171-177
    • Buehler, E.V.1
  • 10
    • 47249149126 scopus 로고
    • Guidelines for testing of chemicals
    • OECD:, OECD
    • OECD: Guidelines for testing of chemicals. No 406: skin sensitization. OECD, 1992.
    • (1992) skin sensitization
  • 13
    • 0035697810 scopus 로고    scopus 로고
    • ICCVAM evaluation of the murine local lymph node assay. Conclusions and recommendations of an independent scientific peer review panel
    • Dean JH, Twerdok LE, Tice RR, Sailstad DM, Hattan DG, Stokes WS: ICCVAM evaluation of the murine local lymph node assay. Conclusions and recommendations of an independent scientific peer review panel. Regul Toxicol Pharmacol 2001;34:258-273.
    • (2001) Regul Toxicol Pharmacol , vol.34 , pp. 258-273
    • Dean, J.H.1    Twerdok, L.E.2    Tice, R.R.3    Sailstad, D.M.4    Hattan, D.G.5    Stokes, W.S.6
  • 14
    • 0346122894 scopus 로고    scopus 로고
    • Nickel, chromium and cobalt in consumer products: Revisiting safe levels in the new millennium
    • Basketter DA, Angelini G, Ingber A, Kern PS, Menne T: Nickel, chromium and cobalt in consumer products: revisiting safe levels in the new millennium. Contact Dermatitis 2003;49:1-7.
    • (2003) Contact Dermatitis , vol.49 , pp. 1-7
    • Basketter, D.A.1    Angelini, G.2    Ingber, A.3    Kern, P.S.4    Menne, T.5
  • 15
    • 0036877375 scopus 로고    scopus 로고
    • A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis
    • Felter SP, Robinson MK, Basketter DA, Gerberick GF: A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis. Contact Dermatitis 2002;47:257-266.
    • (2002) Contact Dermatitis , vol.47 , pp. 257-266
    • Felter, S.P.1    Robinson, M.K.2    Basketter, D.A.3    Gerberick, G.F.4
  • 19
    • 84895379974 scopus 로고    scopus 로고
    • Molecular aspects of allergic contact dermatitis
    • Frosch P, MennA T, Lepoittevin J-P eds, Heidelberg, Springer
    • Lepoittevin J-P: Molecular aspects of allergic contact dermatitis; in Frosch P, MennA T, Lepoittevin J-P (eds): Contact Dermatitis. Heidelberg, Springer, 2006, pp 45-68.
    • (2006) Contact Dermatitis , pp. 45-68
    • Lepoittevin, J.-P.1
  • 21
    • 0029021329 scopus 로고
    • Streptozotocin: Inherent but not expressed skin sensitizing activity
    • Ashby J, Hilton J, Dearman RJ, Kimber I: Streptozotocin: inherent but not expressed skin sensitizing activity. Contact Dermatitis 1995;33:165-167.
    • (1995) Contact Dermatitis , vol.33 , pp. 165-167
    • Ashby, J.1    Hilton, J.2    Dearman, R.J.3    Kimber, I.4
  • 22
    • 0346743727 scopus 로고
    • Studies on the sensitization of animals with simple chemical compounds. 6. Experiments on the sensitization of guinea pigs to poison ivy
    • Landsteiner K, Chase MW: Studies on the sensitization of animals with simple chemical compounds. 6. Experiments on the sensitization of guinea pigs to poison ivy. J Exp Med 1939;69:767-784.
    • (1939) J Exp Med , vol.69 , pp. 767-784
    • Landsteiner, K.1    Chase, M.W.2
  • 23
    • 84973718396 scopus 로고
    • Studies on the sensitization of animals with simple chemical compounds
    • Landsteiner K, Jacobs J: Studies on the sensitization of animals with simple chemical compounds. J Exp Med 1935;61:643-657.
    • (1935) J Exp Med , vol.61 , pp. 643-657
    • Landsteiner, K.1    Jacobs, J.2
  • 24
    • 0002378635 scopus 로고
    • Group sensitization to compounds of quinine structure and its biochemical basis. Role of these substances in cancer
    • Mayer RL: Group sensitization to compounds of quinine structure and its biochemical basis. Role of these substances in cancer. Prog Allergy 1954;4:79-172.
    • (1954) Prog Allergy , vol.4 , pp. 79-172
    • Mayer, R.L.1
  • 26
    • 0031960195 scopus 로고    scopus 로고
    • Mechanism of allergic contact dermatitis from propacetamol: Sensitization to activated N,N-diethylglycine
    • Berl V, Barbaud A, Lepoittevin JP: Mechanism of allergic contact dermatitis from propacetamol: sensitization to activated N,N-diethylglycine. Contact Dermatitis 1998;38:185-188.
    • (1998) Contact Dermatitis , vol.38 , pp. 185-188
    • Berl, V.1    Barbaud, A.2    Lepoittevin, J.P.3
  • 27
    • 0030938165 scopus 로고    scopus 로고
    • Skin sensitization to eugenol and isoeugenol in mice: Possible metabolic pathways involving ortho-quinone and quinone methide intermediates
    • Bertrand F, Basketter DA, Roberts DW, Lepoittevin JP: Skin sensitization to eugenol and isoeugenol in mice: possible metabolic pathways involving ortho-quinone and quinone methide intermediates. Chem Res Toxicol 1997;10:335-343.
    • (1997) Chem Res Toxicol , vol.10 , pp. 335-343
    • Bertrand, F.1    Basketter, D.A.2    Roberts, D.W.3    Lepoittevin, J.P.4
  • 28
    • 0028270553 scopus 로고
    • Structure-activity relationships for contact allergenic potential of gamma,gamma-dimethyl-gamma-butyrolactone derivatives. 2. Quantitative structure-skin sensitization relationships for alpha-subst ituted-alpha-methyl- gamma, gamma-dimethyl-gamma-butyrolactone s
    • Franot C, Roberts DW, Basketter DA, Benezra C, Lepoittevin JP: Structure-activity relationships for contact allergenic potential of gamma,gamma-dimethyl-gamma-butyrolactone derivatives. 2. Quantitative structure-skin sensitization relationships for alpha-subst ituted-alpha-methyl- gamma, gamma-dimethyl-gamma-butyrolactone s. Chem Res Toxicol 1994;7:307-312.
    • (1994) Chem Res Toxicol , vol.7 , pp. 307-312
    • Franot, C.1    Roberts, D.W.2    Basketter, D.A.3    Benezra, C.4    Lepoittevin, J.P.5
  • 29
    • 0028967284 scopus 로고
    • Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids
    • Lepoittevin JP, Drieghe J, Dooms-Goossens A: Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids. Arch Dermatol 1995;131:31-37.
    • (1995) Arch Dermatol , vol.131 , pp. 31-37
    • Lepoittevin, J.P.1    Drieghe, J.2    Dooms-Goossens, A.3
  • 30
    • 0026637630 scopus 로고
    • 13C-enriched methyl alkanesulfonates: New lipophilic methylating agents for the identification of nucleophilic amino acids of proteins by NMR
    • 13C-enriched methyl alkanesulfonates: new lipophilic methylating agents for the identification of nucleophilic amino acids of proteins by NMR. Tetrahedron Lett 1992;33:3875-3878.
    • (1992) Tetrahedron Lett , vol.33 , pp. 3875-3878
    • Lepoittevin, J.-P.1    Benezra, C.2
  • 31
    • 0020355123 scopus 로고
    • The derivation of quantitative correlations between skin sensitisation and physio-chemical parameters for alkylating agents, and their application to experimental data for sultones
    • Roberts DW, Williams DL: The derivation of quantitative correlations between skin sensitisation and physio-chemical parameters for alkylating agents, and their application to experimental data for sultones. J Theor Biol 1982;99:807-825.
    • (1982) J Theor Biol , vol.99 , pp. 807-825
    • Roberts, D.W.1    Williams, D.L.2
  • 33
    • 0345039474 scopus 로고    scopus 로고
    • Xenobiotics as skin sensitizers: Metabolic activation and detoxification, and protein-binding mechanisms
    • Smith CK, Hotchkiss SAM eds, London, Taylor and Francis
    • Smith CK, Hotchkiss SAM: Xenobiotics as skin sensitizers: metabolic activation and detoxification, and protein-binding mechanisms; in Smith CK, Hotchkiss SAM (eds): Allergic Contact Dermatitis: Chemical and Metabolic Mechanisms. London, Taylor and Francis, 2001, pp 119-205.
    • (2001) Allergic Contact Dermatitis: Chemical and Metabolic Mechanisms , pp. 119-205
    • Smith, C.K.1    Hotchkiss, S.A.M.2
  • 34
    • 25444520273 scopus 로고    scopus 로고
    • Skin sensitization: Reaction mechanistic applicability domains for structure-activity relationships
    • Aptula AO, Patlewicz G, Roberts DW: Skin sensitization: reaction mechanistic applicability domains for structure-activity relationships. Chem Res Toxicol 2005;18:1420-1426.
    • (2005) Chem Res Toxicol , vol.18 , pp. 1420-1426
    • Aptula, A.O.1    Patlewicz, G.2    Roberts, D.W.3
  • 35
    • 33749004016 scopus 로고    scopus 로고
    • Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization
    • Roberts DW, Aptula AO, Patlewicz G: Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization. Chem Res Toxicol 2006;19:1228-1233.
    • (2006) Chem Res Toxicol , vol.19 , pp. 1228-1233
    • Roberts, D.W.1    Aptula, A.O.2    Patlewicz, G.3
  • 36
    • 38649142506 scopus 로고    scopus 로고
    • Determinants of skin sensitisation potential
    • E-pub ahead of print
    • Roberts DW, Aptula AO: Determinants of skin sensitisation potential. J Appl Toxicol 2007, E-pub ahead of print.
    • (2007) J Appl Toxicol
    • Roberts, D.W.1    Aptula, A.O.2
  • 38
    • 47249141080 scopus 로고
    • On group specific A substances. 3. The substance in commercial pepsin
    • Landsteiner K, Chase MW: On group specific A substances. 3. The substance in commercial pepsin. J Exp Med 1936;63:813-817.
    • (1936) J Exp Med , vol.63 , pp. 813-817
    • Landsteiner, K.1    Chase, M.W.2
  • 39
    • 85025403160 scopus 로고
    • Studies on the sensitization of animals with simple chemical compounds
    • Landsteiner K, Jacobs J: Studies on the sensitization of animals with simple chemical compounds. J Exp Med 1936;64:625-639.
    • (1936) J Exp Med , vol.64 , pp. 625-639
    • Landsteiner, K.1    Jacobs, J.2
  • 40
    • 0029851815 scopus 로고    scopus 로고
    • An interlaboratory evaluation of the Buehler test for the identification and classification of skin sensitizers
    • Basketter DA, Gerberick GF: An interlaboratory evaluation of the Buehler test for the identification and classification of skin sensitizers. Contact Dermatitis 1996;35:146-151.
    • (1996) Contact Dermatitis , vol.35 , pp. 146-151
    • Basketter, D.A.1    Gerberick, G.F.2
  • 41
    • 33749561246 scopus 로고    scopus 로고
    • Identification and classification of skin sensitizers: Identifying false positives and false negatives
    • Basketter DA, McFadden J, Evans P, Andersen KE, Jowsey I: Identification and classification of skin sensitizers: identifying false positives and false negatives. Contact Dermatitis 2006;55:268-273.
    • (2006) Contact Dermatitis , vol.55 , pp. 268-273
    • Basketter, D.A.1    McFadden, J.2    Evans, P.3    Andersen, K.E.4    Jowsey, I.5
  • 43
    • 0026504266 scopus 로고
    • The murine local lymph node assay: A commentary on collaborative studies and new directions
    • Kimber I, Basketter DA: The murine local lymph node assay: a commentary on collaborative studies and new directions. Food Chem Toxicol 1992;30:165-169.
    • (1992) Food Chem Toxicol , vol.30 , pp. 165-169
    • Kimber, I.1    Basketter, D.A.2
  • 46
    • 0030266185 scopus 로고    scopus 로고
    • The local lymph node assay: A viable alternative to currently accepted skin sensitization tests
    • Basketter DA, Gerberick GF, Kimber I, Loveless SE: The local lymph node assay: a viable alternative to currently accepted skin sensitization tests. Food Chem Toxicol 1996;34:985-997.
    • (1996) Food Chem Toxicol , vol.34 , pp. 985-997
    • Basketter, D.A.1    Gerberick, G.F.2    Kimber, I.3    Loveless, S.E.4
  • 48
    • 0000073491 scopus 로고    scopus 로고
    • Statement on the validity of the local lymph node assay for skin sensitisation testing. ECVAM joint research centre, European commission, Ispra
    • Balls M, Hellsten E: Statement on the validity of the local lymph node assay for skin sensitisation testing. ECVAM joint research centre, European commission, Ispra. Altern Lab Anim 2000;28:366-367.
    • (2000) Altern Lab Anim , vol.28 , pp. 366-367
    • Balls, M.1    Hellsten, E.2
  • 50
    • 0027340223 scopus 로고
    • Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays
    • Basketter DA, Selbie E, Scholes EW, Lees D, Kimber I, Botham PA: Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays. Food Chem Toxicol 1993;31:63-67.
    • (1993) Food Chem Toxicol , vol.31 , pp. 63-67
    • Basketter, D.A.1    Selbie, E.2    Scholes, E.W.3    Lees, D.4    Kimber, I.5    Botham, P.A.6
  • 51
    • 0345802751 scopus 로고    scopus 로고
    • Use of the local lymph node assay in the evaluation of the sensitizing potential of pharmaceutical process intermediates
    • Durand G, de Burlet G, Virat M, Nauman BD: Use of the local lymph node assay in the evaluation of the sensitizing potential of pharmaceutical process intermediates. Contact Dermatitis 2003;49:148-154.
    • (2003) Contact Dermatitis , vol.49 , pp. 148-154
    • Durand, G.1    de Burlet, G.2    Virat, M.3    Nauman, B.D.4
  • 53
    • 28444479129 scopus 로고    scopus 로고
    • The local lymph node assay being too sensitive?
    • Hans-Werner V, Jurgen AH: The local lymph node assay being too sensitive? Arch Toxicol 2005;79:721-728.
    • (2005) Arch Toxicol , vol.79 , pp. 721-728
    • Hans-Werner, V.1    Jurgen, A.H.2
  • 54
    • 34547811350 scopus 로고    scopus 로고
    • The murine local lymph node assay: Regulatory and potency considerations under reach
    • McGarry HF: The murine local lymph node assay: regulatory and potency considerations under reach. Toxicology 2007;238:71-89.
    • (2007) Toxicology , vol.238 , pp. 71-89
    • McGarry, H.F.1
  • 55
    • 0032489787 scopus 로고    scopus 로고
    • Strategies for identifying false positive responses in predictive skin sensitization tests
    • Basketter DA, Gerberick GF, Kimber I: Strategies for identifying false positive responses in predictive skin sensitization tests. Food Chem Toxicol 1998;36:327-333.
    • (1998) Food Chem Toxicol , vol.36 , pp. 327-333
    • Basketter, D.A.1    Gerberick, G.F.2    Kimber, I.3
  • 56
    • 33845536212 scopus 로고    scopus 로고
    • Information derived from sensitization test methods: Test sensitivity, false positives and false negatives
    • Basketter DA, Kimber I: Information derived from sensitization test methods: test sensitivity, false positives and false negatives. Contact Dermatitis 2007;56:1-4.
    • (2007) Contact Dermatitis , vol.56 , pp. 1-4
    • Basketter, D.A.1    Kimber, I.2
  • 59
    • 47249154618 scopus 로고    scopus 로고
    • Skin sensitization: Strategies for risk assessment and risk management
    • submitted
    • Basketter DA: Skin sensitization: strategies for risk assessment and risk management. Br J Dermatol, submitted.
    • Br J Dermatol
    • Basketter, D.A.1
  • 62
    • 21744432479 scopus 로고    scopus 로고
    • Contact sensitization: A new approach to risk assessment
    • Kimber I, Basketter DA: Contact sensitization: a new approach to risk assessment. Hum Ecol Risk Assess 1997;3:385-395.
    • (1997) Hum Ecol Risk Assess , vol.3 , pp. 385-395
    • Kimber, I.1    Basketter, D.A.2
  • 63
    • 0025610036 scopus 로고
    • A quantitative structure activity/dose response relationship for contact allergic potential of alkyl group transfer agents
    • Roberts DW, Basketter DA: A quantitative structure activity/dose response relationship for contact allergic potential of alkyl group transfer agents. Contact Dermatitis 1990;23:331-335.
    • (1990) Contact Dermatitis , vol.23 , pp. 331-335
    • Roberts, D.W.1    Basketter, D.A.2
  • 64
    • 0028191789 scopus 로고
    • Multivariate QSAR analysis of a skin sensitization database
    • Cronin MT, Basketter DA: Multivariate QSAR analysis of a skin sensitization database. SAR QSAR Environ Res 1994;2:159-179.
    • (1994) SAR QSAR Environ Res , vol.2 , pp. 159-179
    • Cronin, M.T.1    Basketter, D.A.2
  • 65
    • 0026644007 scopus 로고
    • The value of the local lymph node assay in quantitative structure-activity investigations
    • Basketter DA, Roberts DW, Cronin M, Scholes EW: The value of the local lymph node assay in quantitative structure-activity investigations. Contact Dermatitis 1992;27:137-142.
    • (1992) Contact Dermatitis , vol.27 , pp. 137-142
    • Basketter, D.A.1    Roberts, D.W.2    Cronin, M.3    Scholes, E.W.4
  • 68
    • 0032776406 scopus 로고    scopus 로고
    • A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses
    • Basketter DA, Lea LJ, Dickens A, Briggs D, Pate I, Dearman RJ, Kimber I: A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses. J Appl Toxicol 1999;19:261-266.
    • (1999) J Appl Toxicol , vol.19 , pp. 261-266
    • Basketter, D.A.1    Lea, L.J.2    Dickens, A.3    Briggs, D.4    Pate, I.5    Dearman, R.J.6    Kimber, I.7
  • 71
    • 34447295889 scopus 로고    scopus 로고
    • The local lymph node assay and the assessment of relative potency: Status of validation
    • Basketter DA, Gerberick F, Kimber I: The local lymph node assay and the assessment of relative potency: status of validation. Contact Dermatitis 2007;57:70-75.
    • (2007) Contact Dermatitis , vol.57 , pp. 70-75
    • Basketter, D.A.1    Gerberick, F.2    Kimber, I.3
  • 73
    • 0242456077 scopus 로고    scopus 로고
    • Proposal for a risk assessment methodology for skin sensitization based on sensitization potency data
    • Griem P, Goebel C, Scheffler H: Proposal for a risk assessment methodology for skin sensitization based on sensitization potency data. Regul Toxicol Pharmacol 2003;38:269-290.
    • (2003) Regul Toxicol Pharmacol , vol.38 , pp. 269-290
    • Griem, P.1    Goebel, C.2    Scheffler, H.3
  • 74
    • 1842835106 scopus 로고    scopus 로고
    • Quantitative relationship between the local lymph node assay and human skin sensitization assays
    • Schneider K, Akkan Z: Quantitative relationship between the local lymph node assay and human skin sensitization assays. Regul Toxicol Pharmacol 2004;39:245-255.
    • (2004) Regul Toxicol Pharmacol , vol.39 , pp. 245-255
    • Schneider, K.1    Akkan, Z.2
  • 76
    • 27144479286 scopus 로고    scopus 로고
    • Hapten-protein binding: From theory to practical application in the in vitro prediction of skin sensitization
    • Divkovic M, Pease CK, Gerberick GF, Basketter DA: Hapten-protein binding: from theory to practical application in the in vitro prediction of skin sensitization. Contact Dermatitis 2005;53:189-200.
    • (2005) Contact Dermatitis , vol.53 , pp. 189-200
    • Divkovic, M.1    Pease, C.K.2    Gerberick, G.F.3    Basketter, D.A.4
  • 78
    • 33745996629 scopus 로고    scopus 로고
    • A future approach to measuring relative skin sensitising potency: A proposal
    • Jowsey IR, Basketter DA, Westmoreland C, Kimber I: A future approach to measuring relative skin sensitising potency: a proposal. J Appl Toxicol 2006;26:341-350.
    • (2006) J Appl Toxicol , vol.26 , pp. 341-350
    • Jowsey, I.R.1    Basketter, D.A.2    Westmoreland, C.3    Kimber, I.4
  • 81
    • 34547905381 scopus 로고    scopus 로고
    • Identification and characterization of allergens: In vitro approaches
    • Basketter DA, Maxwell G: Identification and characterization of allergens: in vitro approaches. Expert Rev Dermatol 2007;2:471-479.
    • (2007) Expert Rev Dermatol , vol.2 , pp. 471-479
    • Basketter, D.A.1    Maxwell, G.2
  • 82
    • 33750927006 scopus 로고    scopus 로고
    • Structure-activity relationships for skin sensitization: Recent improvements to Derek for Windows
    • Langton K, Patlewicz GY, Long A, Marchant CA, Basketter DA: Structure-activity relationships for skin sensitization: recent improvements to Derek for Windows. Contact Dermatitis 2006;55:342-347.
    • (2006) Contact Dermatitis , vol.55 , pp. 342-347
    • Langton, K.1    Patlewicz, G.Y.2    Long, A.3    Marchant, C.A.4    Basketter, D.A.5
  • 84
    • 34447547764 scopus 로고    scopus 로고
    • Quantification of chemical peptide reactivity for screening contact allergens: A classification tree model approach
    • Gerberick GF, Vassallo JD, Foertsch LM, Price BB, Chaney JG, Lepoittevin JP: Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach. Toxicol Sci 2007;97:417-427.
    • (2007) Toxicol Sci , vol.97 , pp. 417-427
    • Gerberick, G.F.1    Vassallo, J.D.2    Foertsch, L.M.3    Price, B.B.4    Chaney, J.G.5    Lepoittevin, J.P.6
  • 85
    • 35649009496 scopus 로고    scopus 로고
    • Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro
    • Natsch A, Gfeller H, Rothaupt M, Ellis G: Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. Toxicol In Vitro 2007;21:1220-1226.
    • (2007) Toxicol In Vitro , vol.21 , pp. 1220-1226
    • Natsch, A.1    Gfeller, H.2    Rothaupt, M.3    Ellis, G.4
  • 87
    • 33745450390 scopus 로고    scopus 로고
    • Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT). 1. Optimization of the h-CLAT protocol
    • Ashikaga T, Yoshida Y, Hirota M, Yoneyama K, Itagaki H, Sakaguchi H, Miyazawa M, Ito Y, Suzuki H, Toyoda H: Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). 1. Optimization of the h-CLAT protocol. Toxicol In Vitro 2006;20:767-773.
    • (2006) Toxicol In Vitro , vol.20 , pp. 767-773
    • Ashikaga, T.1    Yoshida, Y.2    Hirota, M.3    Yoneyama, K.4    Itagaki, H.5    Sakaguchi, H.6    Miyazawa, M.7    Ito, Y.8    Suzuki, H.9    Toyoda, H.10
  • 88
    • 33947719856 scopus 로고    scopus 로고
    • Assessment of the U937 cell line for the detection of contact allergens
    • Python F, Goebel C, Aeby P: Assessment of the U937 cell line for the detection of contact allergens. Toxicol Appl Pharmacol 2007;220:113-124.
    • (2007) Toxicol Appl Pharmacol , vol.220 , pp. 113-124
    • Python, F.1    Goebel, C.2    Aeby, P.3
  • 89
    • 33745468021 scopus 로고    scopus 로고
    • Development of an in vitro skin sensitization test using human cell lines: Human cell line activation test (h-CLAT). 2. An inter-laboratory study of the h-CLAT
    • Sakaguchi H, Ashikaga T, Miyazawa M, Yoshida Y, Ito Y, Yoneyama K, Hirota M, Itagaki H, Toyoda H, Suzuki H: Development of an in vitro skin sensitization test using human cell lines: human cell line activation test (h-CLAT). 2. An inter-laboratory study of the h-CLAT. Toxicol In Vitro 2006;20:774-784.
    • (2006) Toxicol In Vitro , vol.20 , pp. 774-784
    • Sakaguchi, H.1    Ashikaga, T.2    Miyazawa, M.3    Yoshida, Y.4    Ito, Y.5    Yoneyama, K.6    Hirota, M.7    Itagaki, H.8    Toyoda, H.9    Suzuki, H.10
  • 91
    • 39149086011 scopus 로고    scopus 로고
    • Skin sensitizers induce antioxidant response element dependent genes: Application to the in vitro testing of the sensitization potential of chemicals
    • Natsch A, Emter R: Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals. Toxicol Sci 2008;102:110-119.
    • (2008) Toxicol Sci , vol.102 , pp. 110-119
    • Natsch, A.1    Emter, R.2


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