Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Acta Crystallographica Section D: Biological Crystallography

Volumn 68, Issue 7, 2012, Pages 784-793

  Lee, Sang Jae ^a,b   Lee, Seung Jae ^c   Lee, Seung Kyu ^b   Yoon, Hye Jin ^b   Lee, Hyung Ho ^d   Kim, Kyeong Kyu ^e   Lee, Bong Jin ^b   Lee, Byung Il ^a   Suh, Se Won ^b  

^a National Cancer Center   (South Korea)

^b Seoul National University   (South Korea)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d Kookmin University   (South Korea)

^e Sungkyunkwan University   (South Korea)

Author keywords

antimicrobial agents; PDF; peptide deformylases; Staphylococcus aureus

Indexed keywords

AMIDASE; ANTIINFECTIVE AGENT; ENZYME INHIBITOR; PEPTIDE DEFORMYLASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HAEMOPHILUS INFLUENZAE; HUMAN; KLEBSIELLA PNEUMONIAE; METABOLISM; MICROBIOLOGY; MORAXELLA CATARRHALIS; PROTEIN CONFORMATION; RADIATION EXPOSURE; RESPIRATORY TRACT INFECTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; X RAY CRYSTALLOGRAPHY;

AMIDOHYDROLASES; ANTI-BACTERIAL AGENTS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HAEMOPHILUS INFLUENZAE; HUMANS; KLEBSIELLA PNEUMONIAE; MODELS, MOLECULAR; MORAXELLA (BRANHAMELLA) CATARRHALIS; PROTEIN CONFORMATION; RESPIRATORY TRACT INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

HAEMOPHILUS INFLUENZAE; KLEBSIELLA PNEUMONIAE; MORAXELLA CATARRHALIS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 84863489881     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444912011912     Document Type: Article

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