Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: Snapshots of the oxygen sensitivity of peptide deformylase

Journal of Molecular Biology

Volumn 330, Issue 2, 2003, Pages 309-321

  Kreusch, Andreas ^a   Spraggon, Glen ^a   Lee, Chris C ^a   Klock, Heath ^a   McMullan, Daniel ^a   Ng, Ken ^a   Shin, Tanya ^a   Vincent, Juli ^a   Warner, Ian ^a   Ericson, Christer ^a   Lesley, Scott A ^a  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

Antibiotic; Crystal structure; Drug design; Metalloprotease; Peptide deformylase

Indexed keywords

CYSTEINE; METAL; OXYGEN; PEPTIDE DEFORMYLASE; PEPTIDE DEFORMYLASE INHIBITOR;

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME STABILITY; ENZYME STRUCTURE; EUKARYOTE; NONHUMAN; OXIDATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIA; STRUCTURE ANALYSIS; THERMOTOGA MARITIMA; X RAY ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; NEGIBACTERIA; PLASMODIUM FALCIPARUM; POSIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE; THERMOTOGA; THERMOTOGA MARITIMA;

EID: 0037785128     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00596-5     Document Type: Article

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