Peptide deformylase in Staphylococcus aureus: Resistance to inhibition is mediated by mutations in the formyltransferase gene

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 7, 2000, Pages 1825-1831

  Margolis, Peter S ^a   Hackbarth, Corinne J ^a   Young, Dennis C ^a   Wang, Wen ^a   Chen, Dawn ^a   Yuan, Zhengyu ^a   White, Richard ^a   Trias, Joaquim ^a  

^a Versicor Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINONIN; BACTERIAL DNA; BACTERIAL ENZYME; CHLORAMPHENICOL; CLINDAMYCIN; ERYTHROMYCIN; ISOENZYME; KANAMYCIN; LINEZOLID; PEPTIDE DEFORMYLASE; TETRACYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; CROSS RESISTANCE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ESCHERICHIA COLI; FEMALE; GENE INACTIVATION; GENE LOCUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SOFT TISSUE INFECTION; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE;

AMIDOHYDROLASES; AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, MICROBIAL; FEMALE; HYDROXAMIC ACIDS; HYDROXYMETHYL AND FORMYL TRANSFERASES; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 0033919993     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.7.1825-1831.2000     Document Type: Article

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