Advances in Smoothened-targeting therapies for pancreatic cancer: Implication for drug discovery from herbal medicines

Journal of Chinese Integrative Medicine

Volumn 10, Issue 3, 2012, Pages 256-263

  Han, Jin Bin ^a   Hua, Yong Qiang ^a   Chen, Lian Yu ^a   Liu, Lu Ming ^a  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

Hedgehog proteins; Medicinal; Neoplastic stem cells; Pancreatic neoplasms; Plants; Review; Signal transduction; Smoothened

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPAMINE; ERISMODEGIB; GDC 0049; IPI 926; PF 04443313; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; XL 139;

ALOPECIA; ANOREXIA; BASAL CELL CARCINOMA; CANCER STEM CELL; DRUG MECHANISM; GENE EXPRESSION; GENE MUTATION; HERBAL MEDICINE; HUMAN; HYPODYNAMIA; HYPONATREMIA; MARASMUS; PANCREAS CANCER; PATHOGENESIS; REVIEW; TREATMENT RESPONSE; TUMOR MICROENVIRONMENT; WEAKNESS;

EID: 84863388356     PISSN: 16721977     EISSN: None     Source Type: Journal    
DOI: 10.3736/jcim20120303     Document Type: Review

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