메뉴 건너뛰기




Volumn 32, Issue 2, 2006, Pages 119-129

Hedgehog signaling in the normal and diseased pancreas

Author keywords

Chronic pancreatitis; Indian hedgehog; Pancreatic cancer; Patched; Smoothened; Sonic hedgehog

Indexed keywords

CYCLOPAMINE; GENE PRODUCT; HEDGEHOG INTERACTING PROTEIN; LIGAND; REGULATOR PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

EID: 33646058889     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000202937.55460.0c     Document Type: Review
Times cited : (65)

References (170)
  • 1
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in drosophila
    • Nusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in drosophila. Nature. 1980;287(5785):795-801.
    • (1980) Nature , vol.287 , Issue.5785 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 2
    • 0027756145 scopus 로고
    • Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
    • Echelard Y, Epstein DJ, St-Jacques B, et al. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 1993;75(7):1417-1430.
    • (1993) Cell , vol.75 , Issue.7 , pp. 1417-1430
    • Echelard, Y.1    Epstein, D.J.2    St-Jacques, B.3
  • 3
    • 23444440157 scopus 로고
    • Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
    • Roelink H, Augsburger A, Heemskerk J, et al. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell. 1994;76(4):761-775.
    • (1994) Cell , vol.76 , Issue.4 , pp. 761-775
    • Roelink, H.1    Augsburger, A.2    Heemskerk, J.3
  • 4
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle RD, Johnson RL, Laufer E, et al. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell. 1993;75(7):1401-1416.
    • (1993) Cell , vol.75 , Issue.7 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3
  • 5
    • 0029844192 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog signaling proteins in animal development
    • Porter JA, Young KE, Beachy PA. Cholesterol modification of hedgehog signaling proteins in animal development. Science. 1996;274(5285):255-259.
    • (1996) Science , vol.274 , Issue.5285 , pp. 255-259
    • Porter, J.A.1    Young, K.E.2    Beachy, P.A.3
  • 6
    • 15844386540 scopus 로고    scopus 로고
    • Hedgehog patterning activity: Role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain
    • Porter JA, Ekker SC, Park WJ, et al. Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell. 1996;86(1):21-34.
    • (1996) Cell , vol.86 , Issue.1 , pp. 21-34
    • Porter, J.A.1    Ekker, S.C.2    Park, W.J.3
  • 7
    • 0029948270 scopus 로고    scopus 로고
    • Biochemical evidence that patched is the hedgehog receptor
    • Marigo V, Davey RA, Zuo Y, et al. Biochemical evidence that patched is the hedgehog receptor. Nature. 1996;384(6605):176-179.
    • (1996) Nature , vol.384 , Issue.6605 , pp. 176-179
    • Marigo, V.1    Davey, R.A.2    Zuo, Y.3
  • 8
    • 0011102935 scopus 로고    scopus 로고
    • The tumour-suppressor gene patched encodes a candidate receptor for sonic hedgehog
    • Stone DM, Hynes M, Armanini M, et al. The tumour-suppressor gene patched encodes a candidate receptor for sonic hedgehog. Nature. 1996;384(6605):129-134.
    • (1996) Nature , vol.384 , Issue.6605 , pp. 129-134
    • Stone, D.M.1    Hynes, M.2    Armanini, M.3
  • 9
    • 0037172658 scopus 로고    scopus 로고
    • Sonic hedgehog induces the segregation of patched and smoothened in endosomes
    • Incardona JP, Gruenberg J, Roelink H. Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr Biol. 2002;12(12):983-995.
    • (2002) Curr Biol , vol.12 , Issue.12 , pp. 983-995
    • Incardona, J.P.1    Gruenberg, J.2    Roelink, H.3
  • 10
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001;15(23):3059-3087.
    • (2001) Genes Dev , vol.15 , Issue.23 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 11
    • 18644368453 scopus 로고    scopus 로고
    • Small-molecule modulators of hedgehog signaling: Identification and characterization of smoothened agonists and antagonists
    • Frank-Kamenetsky M, Zhang XM, Bottega S, et al. Small-molecule modulators of hedgehog signaling: identification and characterization of smoothened agonists and antagonists. J Biol. 2002;1(2):10.
    • (2002) J Biol , vol.1 , Issue.2 , pp. 10
    • Frank-Kamenetsky, M.1    Zhang, X.M.2    Bottega, S.3
  • 12
    • 0034682719 scopus 로고    scopus 로고
    • Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
    • Denef N, Neubuser D, Perez L, et al. Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell. 2000;102(4):521-531.
    • (2000) Cell , vol.102 , Issue.4 , pp. 521-531
    • Denef, N.1    Neubuser, D.2    Perez, L.3
  • 13
    • 0034521484 scopus 로고    scopus 로고
    • Cubitus interruptus - Independent transduction of the hedgehog signal in drosophila
    • Gallet A, Angelats C, Kerridge S, et al. Cubitus interruptus - independent transduction of the hedgehog signal in drosophila. Development. 2000;127(24): 5509-5522.
    • (2000) Development , vol.127 , Issue.24 , pp. 5509-5522
    • Gallet, A.1    Angelats, C.2    Kerridge, S.3
  • 14
    • 0029896212 scopus 로고    scopus 로고
    • Sending and receiving the hedgehog signal: Control by the drosophila gli protein cubitus interruptus
    • Dominguez M, Brunner M, Hafen E, et al. Sending and receiving the hedgehog signal: control by the drosophila gli protein cubitus interruptus. Science. 1996;272(5268):1621-1625.
    • (1996) Science , vol.272 , Issue.5268 , pp. 1621-1625
    • Dominguez, M.1    Brunner, M.2    Hafen, E.3
  • 15
    • 0037067722 scopus 로고    scopus 로고
    • Megalin functions as an endocytic sonic hedgehog receptor
    • McCarthy RA, Barth JL, Chintalapudi MR, et al. Megalin functions as an endocytic sonic hedgehog receptor. J Biol Chem. 2002;277(28):25660-25667.
    • (2002) J Biol Chem , vol.277 , Issue.28 , pp. 25660-25667
    • McCarthy, R.A.1    Barth, J.L.2    Chintalapudi, M.R.3
  • 16
    • 0033580269 scopus 로고    scopus 로고
    • Vertebrate hedgehog signalling modulated by induction of a hedgehog-binding protein
    • Chuang PT, McMahon AP. Vertebrate hedgehog signalling modulated by induction of a hedgehog-binding protein. Nature. 1999;397(6720):617-621.
    • (1999) Nature , vol.397 , Issue.6720 , pp. 617-621
    • Chuang, P.T.1    McMahon, A.P.2
  • 17
    • 0037020216 scopus 로고    scopus 로고
    • Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched
    • Ma Y, Erkner A, Gong R, et al. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell. 2002;111(1):63-75.
    • (2002) Cell , vol.111 , Issue.1 , pp. 63-75
    • Ma, Y.1    Erkner, A.2    Gong, R.3
  • 18
    • 0024199124 scopus 로고
    • Epithelial-mesenchymal interactions in intestinal epithelial differentiation
    • Kedinger M, Simon-Assmann P, Bouziges F, et al. Epithelial-mesenchymal interactions in intestinal epithelial differentiation. Scand J Gastroenterol Suppl. 1988;151:62-69.
    • (1988) Scand J Gastroenterol Suppl , vol.151 , pp. 62-69
    • Kedinger, M.1    Simon-Assmann, P.2    Bouziges, F.3
  • 19
    • 0001763783 scopus 로고
    • Epitheliomesenchymal interaction in pancreatic morphogenesis
    • Golosow N, Grobstein C. Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev Biol. 1962;4:242-255.
    • (1962) Dev Biol , vol.4 , pp. 242-255
    • Golosow, N.1    Grobstein, C.2
  • 20
    • 0033636981 scopus 로고    scopus 로고
    • Regulation of pancreas development by hedgehog signaling
    • Hebrok M, Kim SK, St Jacques B, et al. Regulation of pancreas development by hedgehog signaling. Development. 2000;127(22):4905-4913.
    • (2000) Development , vol.127 , Issue.22 , pp. 4905-4913
    • Hebrok, M.1    Kim, S.K.2    St Jacques, B.3
  • 21
    • 0031260579 scopus 로고    scopus 로고
    • Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
    • Apelqvist A, Ahlgren U, Edlund H. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas. Curr Biol. 1997;7(10):801-804.
    • (1997) Curr Biol , vol.7 , Issue.10 , pp. 801-804
    • Apelqvist, A.1    Ahlgren, U.2    Edlund, H.3
  • 22
    • 14844331446 scopus 로고    scopus 로고
    • Hedgehog signaling regulates expansion of pancreatic epithelial cells
    • Kawahira H, Scheel DW, Smith SB, et al. Hedgehog signaling regulates expansion of pancreatic epithelial cells. Dev Biol. 2005;280(1):111-121.
    • (2005) Dev Biol , vol.280 , Issue.1 , pp. 111-121
    • Kawahira, H.1    Scheel, D.W.2    Smith, S.B.3
  • 23
    • 0034907949 scopus 로고    scopus 로고
    • Sonic hedgehog regulates gastric gland morphogenesis in man and mouse
    • van den Brink GR, Hardwick JC, Tytgat GN, et al. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology. 2001;121(2):317-328.
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 317-328
    • Van Den Brink, G.R.1    Hardwick, J.C.2    Tytgat, G.N.3
  • 24
    • 0032573227 scopus 로고    scopus 로고
    • Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor
    • Kim SK, Melton DA. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. Proc Natl Acad Sci USA. 1998;95(22):13036-13041.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.22 , pp. 13036-13041
    • Kim, S.K.1    Melton, D.A.2
  • 25
    • 0030681247 scopus 로고    scopus 로고
    • Notochord to endoderm signaling is required for pancreas development
    • Kim SK, Hebrok M, Melton DA. Notochord to endoderm signaling is required for pancreas development. Development. 1997;124(21):4243-4252.
    • (1997) Development , vol.124 , Issue.21 , pp. 4243-4252
    • Kim, S.K.1    Hebrok, M.2    Melton, D.A.3
  • 26
    • 2642589990 scopus 로고    scopus 로고
    • Notochord repression of endodermal sonic hedgehog permits pancreas development
    • Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal sonic hedgehog permits pancreas development. Genes Dev. 1998;12(11):1705-1713.
    • (1998) Genes Dev , vol.12 , Issue.11 , pp. 1705-1713
    • Hebrok, M.1    Kim, S.K.2    Melton, D.A.3
  • 27
    • 0033869726 scopus 로고    scopus 로고
    • Activin receptor patterning of foregut organogenesis
    • Kim SK, Hebrok M, Li E, et al. Activin receptor patterning of foregut organogenesis. Genes Dev. 2000;14(15):1866-1871.
    • (2000) Genes Dev , vol.14 , Issue.15 , pp. 1866-1871
    • Kim, S.K.1    Hebrok, M.2    Li, E.3
  • 28
    • 0028837742 scopus 로고
    • Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
    • Bitgood MJ, McMahon AP. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995;172(1):126-138.
    • (1995) Dev Biol , vol.172 , Issue.1 , pp. 126-138
    • Bitgood, M.J.1    McMahon, A.P.2
  • 29
    • 0031798066 scopus 로고    scopus 로고
    • Notes from some crypt watchers: Regulation of renewal in the mouse intestinal epithelium
    • Stappenbeck TS, Wong MH, Saam JR, et al. Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium. Curr Opin Cell Biol. 1998;10(6):702-709.
    • (1998) Curr Opin Cell Biol , vol.10 , Issue.6 , pp. 702-709
    • Stappenbeck, T.S.1    Wong, M.H.2    Saam, J.R.3
  • 30
    • 0033916281 scopus 로고    scopus 로고
    • Hedgehog signals regulate multiple aspects of gastrointestinal development
    • Ramalho-Santos M, Melton DA, McMahon AP. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development. 2000;127(12):2763-2772.
    • (2000) Development , vol.127 , Issue.12 , pp. 2763-2772
    • Ramalho-Santos, M.1    Melton, D.A.2    McMahon, A.P.3
  • 31
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield MF, Jetton TL, Labosky PA, et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996;122(3):983-995.
    • (1996) Development , vol.122 , Issue.3 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3
  • 32
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, et al. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature. 1994;371(6498):606-609.
    • (1994) Nature , vol.371 , Issue.6498 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3
  • 33
    • 13144259688 scopus 로고    scopus 로고
    • Sonic hedgehog signaling is essential for hair development
    • St-Jacques B, Dassule HR, Karavanova I, et al. Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998;8(19):1058-1068.
    • (1998) Curr Biol , vol.8 , Issue.19 , pp. 1058-1068
    • St-Jacques, B.1    Dassule, H.R.2    Karavanova, I.3
  • 34
    • 0033668338 scopus 로고    scopus 로고
    • Hedgehog signaling regulation of insulin production by pancreatic beta-cells
    • Thomas MK, Rastalsky N, Lee JH, et al. Hedgehog signaling regulation of insulin production by pancreatic beta-cells. Diabetes. 2000;49(12):2039-2047.
    • (2000) Diabetes , vol.49 , Issue.12 , pp. 2039-2047
    • Thomas, M.K.1    Rastalsky, N.2    Lee, J.H.3
  • 35
    • 0141842604 scopus 로고    scopus 로고
    • Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis
    • Kayed H, Kleeff J, Keleg S, et al. Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis. J Endocrinol. 2003;178(3):467-478.
    • (2003) J Endocrinol , vol.178 , Issue.3 , pp. 467-478
    • Kayed, H.1    Kleeff, J.2    Keleg, S.3
  • 36
    • 0242270878 scopus 로고    scopus 로고
    • Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
    • Thayer SP, di Magliano MP, Heiser PW, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 2003;425(6960):851-856.
    • (2003) Nature , vol.425 , Issue.6960 , pp. 851-856
    • Thayer, S.P.1    Di Magliano, M.P.2    Heiser, P.W.3
  • 37
    • 0031812947 scopus 로고    scopus 로고
    • Enhanced fibroblast growth factor 5 expression in stromal and exocrine elements of the pancreas in chronic pancreatitis
    • Ishiwata T, Kornmann M, Beger HG, et al. Enhanced fibroblast growth factor 5 expression in stromal and exocrine elements of the pancreas in chronic pancreatitis. Gut. 1998;43(1):134-139.
    • (1998) Gut , vol.43 , Issue.1 , pp. 134-139
    • Ishiwata, T.1    Kornmann, M.2    Beger, H.G.3
  • 38
    • 2942616380 scopus 로고    scopus 로고
    • Indian hedgehog signaling pathway: Expression and regulation in pancreatic cancer
    • Kayed H, Kleeff J, Keleg S, et al. Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer. Int J Cancer. 2004;110(5):668-676.
    • (2004) Int J Cancer , vol.110 , Issue.5 , pp. 668-676
    • Kayed, H.1    Kleeff, J.2    Keleg, S.3
  • 39
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • Herman DM, Karhadkar SS, Maitra A, et al. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature. 2003;425(6960):846-851.
    • (2003) Nature , vol.425 , Issue.6960 , pp. 846-851
    • Herman, D.M.1    Karhadkar, S.S.2    Maitra, A.3
  • 40
    • 17044384984 scopus 로고    scopus 로고
    • Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas
    • Kayed H, Kleeff J, Esposito I, et al. Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas. Mol Carcinog. 2005;42(4):183-192.
    • (2005) Mol Carcinog , vol.42 , Issue.4 , pp. 183-192
    • Kayed, H.1    Kleeff, J.2    Esposito, I.3
  • 41
    • 25144461600 scopus 로고    scopus 로고
    • Aberrant methylation of the human hedgehog interacting protein (hhip) gene in pancreatic neoplasms
    • Martin ST, Sato N, Dhara S, et al. Aberrant methylation of the human hedgehog interacting protein (hhip) gene in pancreatic neoplasms. Cancer Biol Ther. 2005;4(7).
    • (2005) Cancer Biol Ther , vol.4 , Issue.7
    • Martin, S.T.1    Sato, N.2    Dhara, S.3
  • 42
    • 0037314331 scopus 로고    scopus 로고
    • Feedback control of mammalian hedgehog signaling by the hedgehog-binding protein, hip1, modulates Fgf signaling during branching morphogenesis of the lung
    • Chuang PT, Kawcak T, McMahon AP. Feedback control of mammalian hedgehog signaling by the hedgehog-binding protein, hip1, modulates Fgf signaling during branching morphogenesis of the lung. Genes Dev. 2003;17(3):342-347.
    • (2003) Genes Dev , vol.17 , Issue.3 , pp. 342-347
    • Chuang, P.T.1    Kawcak, T.2    McMahon, A.P.3
  • 43
    • 0035863135 scopus 로고    scopus 로고
    • Intercellular signals regulating pancreas development and function
    • Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function. Genes Dev. 2001;15(2):111-127.
    • (2001) Genes Dev , vol.15 , Issue.2 , pp. 111-127
    • Kim, S.K.1    Hebrok, M.2
  • 44
    • 14644423815 scopus 로고    scopus 로고
    • Development and cancer: Lessons learned in the pancreas
    • Heiser PW, Hebrok M. Development and cancer: lessons learned in the pancreas. Cell Cycle. 2004;3(3):270-272.
    • (2004) Cell Cycle , vol.3 , Issue.3 , pp. 270-272
    • Heiser, P.W.1    Hebrok, M.2
  • 45
    • 10744223624 scopus 로고    scopus 로고
    • Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
    • Miyamoto Y, Maitra A, Ghosh B, et al. Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell. 2003;3(6):565-576.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 565-576
    • Miyamoto, Y.1    Maitra, A.2    Ghosh, B.3
  • 46
    • 0028978107 scopus 로고
    • The Suppressor of fused gene encodes a novel PEST protein involved in drosophila segment polarity establishment
    • Pham A, Therond P, Alves G, et al. The Suppressor of fused gene encodes a novel PEST protein involved in drosophila segment polarity establishment. Genetics. 1995;140(2):587-598.
    • (1995) Genetics , vol.140 , Issue.2 , pp. 587-598
    • Pham, A.1    Therond, P.2    Alves, G.3
  • 47
    • 0032492995 scopus 로고    scopus 로고
    • Suppressor of fused links fused and cubitus interruptus on the hedgehog signalling pathway
    • Monnier V, Dussillol F, Alves G, et al. Suppressor of fused links fused and cubitus interruptus on the hedgehog signalling pathway. Curr Biol. 1998;8(10):583-586.
    • (1998) Curr Biol , vol.8 , Issue.10 , pp. 583-586
    • Monnier, V.1    Dussillol, F.2    Alves, G.3
  • 48
    • 0033566844 scopus 로고    scopus 로고
    • Vertebrate homologs of drosophila suppressor of fused interact with the gli family of transcriptional regulators
    • Pearse RV, 2nd, Collier LS, Scott MP, et al. Vertebrate homologs of drosophila suppressor of fused interact with the gli family of transcriptional regulators. Dev Biol. 1999;212(2):323-336.
    • (1999) Dev Biol , vol.212 , Issue.2 , pp. 323-336
    • Pearse II, R.V.1    Collier, L.S.2    Scott, M.P.3
  • 49
    • 0033781026 scopus 로고    scopus 로고
    • Gli regulation by the opposing activities of fused and suppressor of fused
    • Murone M, Luoh SM, Stone D, et al. Gli regulation by the opposing activities of fused and suppressor of fused. Nat Cell Biol. 2000;2(5):310-312.
    • (2000) Nat Cell Biol , vol.2 , Issue.5 , pp. 310-312
    • Murone, M.1    Luoh, S.M.2    Stone, D.3
  • 50
    • 0033386977 scopus 로고    scopus 로고
    • The control of beta-catenin and TCF during embryonic development and cancer
    • Waltzer L, Bienz M. The control of beta-catenin and TCF during embryonic development and cancer. Cancer Metastasis Rev. 1999;18(2):231-246.
    • (1999) Cancer Metastasis Rev , vol.18 , Issue.2 , pp. 231-246
    • Waltzer, L.1    Bienz, M.2
  • 52
    • 0033486152 scopus 로고    scopus 로고
    • Beta-catenin signaling and cancer
    • Morin PJ. Beta-catenin signaling and cancer. Bioessays. 1999;21(12):1021-1030.
    • (1999) Bioessays , vol.21 , Issue.12 , pp. 1021-1030
    • Morin, P.J.1
  • 53
    • 0034673331 scopus 로고    scopus 로고
    • Regulation of beta-catenin signaling in the Wnt pathway
    • Kikuchi A. Regulation of beta-catenin signaling in the Wnt pathway. Biochem Biophys Res Commun. 2000;268(2):243-248.
    • (2000) Biochem Biophys Res Commun , vol.268 , Issue.2 , pp. 243-248
    • Kikuchi, A.1
  • 54
    • 0035955642 scopus 로고    scopus 로고
    • Suppressor of fused negatively regulates beta-catenin signaling
    • Meng X, Poon R, Zhang X, et al. Suppressor of fused negatively regulates beta-catenin signaling. J Biol Chem. 2001;276(43):40113-40119.
    • (2001) J Biol Chem , vol.276 , Issue.43 , pp. 40113-40119
    • Meng, X.1    Poon, R.2    Zhang, X.3
  • 55
    • 0035577867 scopus 로고    scopus 로고
    • Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm
    • Tanaka Y, Kato K, Notohara K, et al. Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm. Cancer Res. 2001;61(23):8401-8404.
    • (2001) Cancer Res , vol.61 , Issue.23 , pp. 8401-8404
    • Tanaka, Y.1    Kato, K.2    Notohara, K.3
  • 56
    • 0141976663 scopus 로고    scopus 로고
    • Mutation of beta-catenin and its protein accumulation in solid and cystic tumor of the pancreas associated with metastasis
    • Miao J, Kusafuka T, Kuroda S, et al. Mutation of beta-catenin and its protein accumulation in solid and cystic tumor of the pancreas associated with metastasis. Int J Mol Med. 2003;11(4):461-464.
    • (2003) Int J Mol Med , vol.11 , Issue.4 , pp. 461-464
    • Miao, J.1    Kusafuka, T.2    Kuroda, S.3
  • 57
    • 33646051105 scopus 로고    scopus 로고
    • The Wnt pathway is active in a small subset of pancreas cancer cell lines
    • Pujal J, Capella G, Real FX. The Wnt pathway is active in a small subset of pancreas cancer cell lines. Biochim Biophys Acta. 2005.
    • (2005) Biochim Biophys Acta
    • Pujal, J.1    Capella, G.2    Real, F.X.3
  • 58
    • 0034650621 scopus 로고    scopus 로고
    • Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)
    • Tole S, Ragsdale CW, Grove EA. Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol. 2000;217(2):254-265.
    • (2000) Dev Biol , vol.217 , Issue.2 , pp. 254-265
    • Tole, S.1    Ragsdale, C.W.2    Grove, E.A.3
  • 59
    • 0033539140 scopus 로고    scopus 로고
    • Cerberus regulates left-right asymmetry of the embryonic head and heart
    • Zhu L, Marvin MJ, Gardiner A, et al. Cerberus regulates left-right asymmetry of the embryonic head and heart. Curr Biol. 1999;9(17):931-938.
    • (1999) Curr Biol , vol.9 , Issue.17 , pp. 931-938
    • Zhu, L.1    Marvin, M.J.2    Gardiner, A.3
  • 60
    • 0033609960 scopus 로고    scopus 로고
    • Hedgehog signaling molecules in bone marrow cells at the initial stage of fracture repair
    • Ito H, Akiyama H, Shigeno C, et al. Hedgehog signaling molecules in bone marrow cells at the initial stage of fracture repair. Biochem Biophys Res Commun. 1999;262(2):443-451.
    • (1999) Biochem Biophys Res Commun , vol.262 , Issue.2 , pp. 443-451
    • Ito, H.1    Akiyama, H.2    Shigeno, C.3
  • 61
    • 0033600139 scopus 로고    scopus 로고
    • Noggin and bone morphogenetic protein-4 coordinately regulate the progression of chondrogenic differentiation in mouse clonal EC cells, ATDC5
    • Ito H, Akiyama H, Shigeno C, et al. Noggin and bone morphogenetic protein-4 coordinately regulate the progression of chondrogenic differentiation in mouse clonal EC cells, ATDC5. Biochem Biophys Res Commun. 1999;260(1):240-244.
    • (1999) Biochem Biophys Res Commun , vol.260 , Issue.1 , pp. 240-244
    • Ito, H.1    Akiyama, H.2    Shigeno, C.3
  • 62
    • 0033590997 scopus 로고    scopus 로고
    • Indian hedgehog in the late-phase differentiation in mouse chondrogenic EC cells, ATDC5: Upregulation of type X collagen and osteoprotegerin ligand mRNAs
    • Akiyama H, Shigeno C, Iyama K, et al. Indian hedgehog in the late-phase differentiation in mouse chondrogenic EC cells, ATDC5: upregulation of type X collagen and osteoprotegerin ligand mRNAs. Biochem Biophys Res Commun. 1999;257(3):814-820.
    • (1999) Biochem Biophys Res Commun , vol.257 , Issue.3 , pp. 814-820
    • Akiyama, H.1    Shigeno, C.2    Iyama, K.3
  • 63
    • 0033231459 scopus 로고    scopus 로고
    • Sonic hedgehog and BMP2 exert opposing actions on proliferation and differentiation of embryonic neural progenitor cells
    • Zhu G, Mehler MF, Zhao J, et al. Sonic hedgehog and BMP2 exert opposing actions on proliferation and differentiation of embryonic neural progenitor cells. Dev Biol. 1999;215(1):118-129.
    • (1999) Dev Biol , vol.215 , Issue.1 , pp. 118-129
    • Zhu, G.1    Mehler, M.F.2    Zhao, J.3
  • 64
    • 0038790788 scopus 로고    scopus 로고
    • Positive and negative regulation of muscle cell identity by members of the hedgehog and TGF-beta gene families
    • Du SJ, Devoto SH, Westerfield M, et al. Positive and negative regulation of muscle cell identity by members of the hedgehog and TGF-beta gene families. J Cell Biol. 1997;139(1):145-156.
    • (1997) J Cell Biol , vol.139 , Issue.1 , pp. 145-156
    • Du, S.J.1    Devoto, S.H.2    Westerfield, M.3
  • 65
    • 0027195937 scopus 로고
    • Enhanced expression of the type II transforming growth factor beta receptor in human pancreatic cancer cells without alteration of type III receptor expression
    • Friess H, Yamanaka Y, Buchler M, et al. Enhanced expression of the type II transforming growth factor beta receptor in human pancreatic cancer cells without alteration of type III receptor expression. Cancer Res. 1993;53(12):2704-2707.
    • (1993) Cancer Res , vol.53 , Issue.12 , pp. 2704-2707
    • Friess, H.1    Yamanaka, Y.2    Buchler, M.3
  • 66
    • 0027131252 scopus 로고
    • Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
    • Friess H, Yamanaka Y, Buchler M, et al. Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology. 1993;105(6):1846-1856.
    • (1993) Gastroenterology , vol.105 , Issue.6 , pp. 1846-1856
    • Friess, H.1    Yamanaka, Y.2    Buchler, M.3
  • 67
    • 0030827414 scopus 로고    scopus 로고
    • Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage
    • Lu Z, Friess H, Graber HU, et al. Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage. Dig Dis Sci. 1997;42(10):2054-2063.
    • (1997) Dig Dis Sci , vol.42 , Issue.10 , pp. 2054-2063
    • Lu, Z.1    Friess, H.2    Graber, H.U.3
  • 68
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 1996;271(5247):350-353.
    • (1996) Science , vol.271 , Issue.5247 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 69
    • 0033573974 scopus 로고    scopus 로고
    • Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer
    • Kleeff J, Maruyama H, Friess H, et al. Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Biochem Biophys Res Commun. 1999;255(2):268-273.
    • (1999) Biochem Biophys Res Commun , vol.255 , Issue.2 , pp. 268-273
    • Kleeff, J.1    Maruyama, H.2    Friess, H.3
  • 70
    • 0033598408 scopus 로고    scopus 로고
    • The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
    • Kleeff J, Ishiwata T, Maruyama H, et al. The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene. 1999;18(39):5363-5372.
    • (1999) Oncogene , vol.18 , Issue.39 , pp. 5363-5372
    • Kleeff, J.1    Ishiwata, T.2    Maruyama, H.3
  • 71
    • 0031694080 scopus 로고    scopus 로고
    • Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer
    • Wagner M, Kleeff J, Lopez ME, et al. Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer. Int J Cancer. 1998;78(2):255-260.
    • (1998) Int J Cancer , vol.78 , Issue.2 , pp. 255-260
    • Wagner, M.1    Kleeff, J.2    Lopez, M.E.3
  • 72
    • 7244234099 scopus 로고    scopus 로고
    • Role of histone H2A ubiquitination in polycomb silencing
    • Wang H, Wang L, Erdjument-Bromage H, et al. Role of histone H2A ubiquitination in polycomb silencing. Nature. 2004;431(7010):873-878.
    • (2004) Nature , vol.431 , Issue.7010 , pp. 873-878
    • Wang, H.1    Wang, L.2    Erdjument-Bromage, H.3
  • 73
    • 1642633053 scopus 로고    scopus 로고
    • Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
    • Leung C, Lingbeek M, Shakhova O, et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature. 2004;428(6980):337-341.
    • (2004) Nature , vol.428 , Issue.6980 , pp. 337-341
    • Leung, C.1    Lingbeek, M.2    Shakhova, O.3
  • 74
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 2003;423(6937):255-260.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 75
    • 0037214382 scopus 로고    scopus 로고
    • Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1
    • Itahana K, Zou Y, Itahana Y, et al. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol Cell Biol. 2003;23(1):389-401.
    • (2003) Mol Cell Biol , vol.23 , Issue.1 , pp. 389-401
    • Itahana, K.1    Zou, Y.2    Itahana, Y.3
  • 76
    • 0028875032 scopus 로고
    • Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut
    • Roberts DJ, Johnson RL, Burke AC, et al. Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development. 1995;121(10):3163-3174.
    • (1995) Development , vol.121 , Issue.10 , pp. 3163-3174
    • Roberts, D.J.1    Johnson, R.L.2    Burke, A.C.3
  • 77
    • 0028569704 scopus 로고
    • Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
    • Laufer E, Nelson CE, Johnson RL, et al. Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell. 1994;79(6):993-1003.
    • (1994) Cell , vol.79 , Issue.6 , pp. 993-1003
    • Laufer, E.1    Nelson, C.E.2    Johnson, R.L.3
  • 78
    • 0032908128 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo
    • Kleeff J, Maruyama H, Ishiwata T, et al. Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo. Gastroenterology. 1999;116(5):1202-1216.
    • (1999) Gastroenterology , vol.116 , Issue.5 , pp. 1202-1216
    • Kleeff, J.1    Maruyama, H.2    Ishiwata, T.3
  • 79
    • 0042134565 scopus 로고    scopus 로고
    • Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
    • Cheng H, Jiang W, Phillips FM, et al. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am. 2003;85-A(8):1544-1552.
    • (2003) J Bone Joint Surg Am , vol.85 , Issue.8 , pp. 1544-1552
    • Cheng, H.1    Jiang, W.2    Phillips, F.M.3
  • 80
    • 0037067699 scopus 로고    scopus 로고
    • Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog
    • Solecki DJ, Gromeier M, Mueller S, et al. Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. J Biol Chem. 2002;277(28):25697-25702.
    • (2002) J Biol Chem , vol.277 , Issue.28 , pp. 25697-25702
    • Solecki, D.J.1    Gromeier, M.2    Mueller, S.3
  • 81
    • 0034255218 scopus 로고    scopus 로고
    • Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: Implications for the pathogenesis of poliomyelitis
    • Gromeier M, Solecki D, Patel DD, et al. Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. Virology. 2000;273(2):248-257.
    • (2000) Virology , vol.273 , Issue.2 , pp. 248-257
    • Gromeier, M.1    Solecki, D.2    Patel, D.D.3
  • 82
    • 0036828685 scopus 로고    scopus 로고
    • Expression of COUP-TFII in metabolic tissues during development
    • Zhang P, Bennoun M, Gogard C, et al. Expression of COUP-TFII in metabolic tissues during development. Mech Dev. 2002;119(1):109-114.
    • (2002) Mech Dev , vol.119 , Issue.1 , pp. 109-114
    • Zhang, P.1    Bennoun, M.2    Gogard, C.3
  • 83
    • 0345120945 scopus 로고    scopus 로고
    • The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development
    • Pereira FA, Qiu Y, Zhou G, et al. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 1999;13(8):1037-1049.
    • (1999) Genes Dev , vol.13 , Issue.8 , pp. 1037-1049
    • Pereira, F.A.1    Qiu, Y.2    Zhou, G.3
  • 84
    • 0030765543 scopus 로고    scopus 로고
    • Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter
    • Krishnan V, Elberg G, Tsai MJ, et al. Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter. Mol Endocrinol. 1997;11(10):1458-1466.
    • (1997) Mol Endocrinol , vol.11 , Issue.10 , pp. 1458-1466
    • Krishnan, V.1    Elberg, G.2    Tsai, M.J.3
  • 85
    • 12344266682 scopus 로고    scopus 로고
    • Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain
    • Saitsu H, Komada M, Suzuki M, et al. Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain. Dev Dyn. 2005;232(2):282-292.
    • (2005) Dev Dyn , vol.232 , Issue.2 , pp. 282-292
    • Saitsu, H.1    Komada, M.2    Suzuki, M.3
  • 86
    • 0034623810 scopus 로고    scopus 로고
    • Identification of synergistic signals initiating inner ear development
    • Ladher RK, Anakwe KU, Gurney AL, et al. Identification of synergistic signals initiating inner ear development. Science. 2000;290(5498):1965-1967.
    • (2000) Science , vol.290 , Issue.5498 , pp. 1965-1967
    • Ladher, R.K.1    Anakwe, K.U.2    Gurney, A.L.3
  • 87
    • 0041030051 scopus 로고    scopus 로고
    • Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    • Zuniga A, Haramis AP, McMahon AP, et al. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 1999;401(6753):598-602.
    • (1999) Nature , vol.401 , Issue.6753 , pp. 598-602
    • Zuniga, A.1    Haramis, A.P.2    McMahon, A.P.3
  • 88
    • 0032491409 scopus 로고    scopus 로고
    • Transformation of tooth type induced by inhibition of BMP signaling
    • Tucker AS, Matthews KL, Sharpe PT. Transformation of tooth type induced by inhibition of BMP signaling. Science. 1998;282(5391):1136-1138.
    • (1998) Science , vol.282 , Issue.5391 , pp. 1136-1138
    • Tucker, A.S.1    Matthews, K.L.2    Sharpe, P.T.3
  • 89
    • 0033976391 scopus 로고    scopus 로고
    • Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch
    • Thomas BL, Liu JK, Rubenstein JL, et al. Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch. Development. 2000;127(2):217-224.
    • (2000) Development , vol.127 , Issue.2 , pp. 217-224
    • Thomas, B.L.1    Liu, J.K.2    Rubenstein, J.L.3
  • 90
    • 0029975823 scopus 로고    scopus 로고
    • Conservation in hedgehog signaling: Induction of a chicken patched homolog by Sonic hedgehog in the developing limb
    • Marigo V, Scott MP, Johnson RL, et al. Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development. 1996;122(4):1225-1233.
    • (1996) Development , vol.122 , Issue.4 , pp. 1225-1233
    • Marigo, V.1    Scott, M.P.2    Johnson, R.L.3
  • 91
    • 0033883281 scopus 로고    scopus 로고
    • Ontogeny of fibroblast growth factors in the early development of the rat endocrine pancreas
    • Arany E, Hill DJ. Ontogeny of fibroblast growth factors in the early development of the rat endocrine pancreas. Pediatr Res. 2000;48(3):389-403.
    • (2000) Pediatr Res , vol.48 , Issue.3 , pp. 389-403
    • Arany, E.1    Hill, D.J.2
  • 92
    • 85047692037 scopus 로고    scopus 로고
    • Role of Foxa-2 in adipocyte metabolism and differentiation
    • Wolfrum C, Shih DQ, Kuwajima S, et al. Role of Foxa-2 in adipocyte metabolism and differentiation. J Clin Invest. 2003;112(3):345-356.
    • (2003) J Clin Invest , vol.112 , Issue.3 , pp. 345-356
    • Wolfrum, C.1    Shih, D.Q.2    Kuwajima, S.3
  • 93
    • 11144244418 scopus 로고    scopus 로고
    • Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
    • Wolfrum C, Asilmaz E, Luca E, et al. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature. 2004;432(7020):1027-1032.
    • (2004) Nature , vol.432 , Issue.7020 , pp. 1027-1032
    • Wolfrum, C.1    Asilmaz, E.2    Luca, E.3
  • 94
    • 0033557490 scopus 로고    scopus 로고
    • Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo
    • Kaestner KH, Katz J, Liu Y, et al. Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev. 1999;13(4):495-504.
    • (1999) Genes Dev , vol.13 , Issue.4 , pp. 495-504
    • Kaestner, K.H.1    Katz, J.2    Liu, Y.3
  • 95
    • 18344404449 scopus 로고    scopus 로고
    • TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation
    • Zannini M, Avantaggiato V, Biffali E, et al. TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J. 1997;16(11):3185-3197.
    • (1997) EMBO J , vol.16 , Issue.11 , pp. 3185-3197
    • Zannini, M.1    Avantaggiato, V.2    Biffali, E.3
  • 96
    • 2442423841 scopus 로고    scopus 로고
    • FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma
    • Eichberger T, Regl G, Ikram MS, et al. FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma. J Invest Dermatol. 2004;122(5):1180-1187.
    • (2004) J Invest Dermatol , vol.122 , Issue.5 , pp. 1180-1187
    • Eichberger, T.1    Regl, G.2    Ikram, M.S.3
  • 97
    • 17344366813 scopus 로고    scopus 로고
    • A mouse model for hereditary thyroid dysgenesis and cleft palate
    • Felice M, Ovitt C, Biffali E, et al. A mouse model for hereditary thyroid dysgenesis and cleft palate. Nat Genet. 1998;19(4):395-398.
    • (1998) Nat Genet , vol.19 , Issue.4 , pp. 395-398
    • Felice, M.1    Ovitt, C.2    Biffali, E.3
  • 98
    • 0037023789 scopus 로고    scopus 로고
    • Haploinsufficiency of the mouse Forkhead Box f1 gene causes defects in gall bladder development
    • Kalinichenko W, Zhou Y, Bhattacharyya D, et al. Haploinsufficiency of the mouse Forkhead Box f1 gene causes defects in gall bladder development. J Biol Chem. 2002;277(14):12369-12374.
    • (2002) J Biol Chem , vol.277 , Issue.14 , pp. 12369-12374
    • Kalinichenko, W.1    Zhou, Y.2    Bhattacharyya, D.3
  • 99
    • 0037153417 scopus 로고    scopus 로고
    • Novel genes regulated by Sonic hedgehog in pluripotent mesenchymal cells
    • Ingram WJ, Wicking CA, Grimmond SM, et al. Novel genes regulated by Sonic hedgehog in pluripotent mesenchymal cells. Oncogene. 2002;21(53):8196-8205.
    • (2002) Oncogene , vol.21 , Issue.53 , pp. 8196-8205
    • Ingram, W.J.1    Wicking, C.A.2    Grimmond, S.M.3
  • 100
    • 0345824722 scopus 로고    scopus 로고
    • Foxg1 suppresses early cortical cell fate
    • Hanashima C, Li SC, Shen L, et al. Foxg1 suppresses early cortical cell fate. Science. 2004;303(5654):56-59.
    • (2004) Science , vol.303 , Issue.5654 , pp. 56-59
    • Hanashima, C.1    Li, S.C.2    Shen, L.3
  • 101
    • 0035949627 scopus 로고    scopus 로고
    • Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver
    • Wang X, Quail E, Hung NJ, et al. Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver. Proc Natl Acad Sci USA. 2001;98(20):11468-11473.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.20 , pp. 11468-11473
    • Wang, X.1    Quail, E.2    Hung, N.J.3
  • 102
    • 0037168526 scopus 로고    scopus 로고
    • The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
    • Wang X, Kiyokawa H, Dennewitz MB, et al. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci USA. 2002;99(26):16881-16886.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.26 , pp. 16881-16886
    • Wang, X.1    Kiyokawa, H.2    Dennewitz, M.B.3
  • 103
    • 0037102232 scopus 로고    scopus 로고
    • FOXM1 is a downstream target of Gli1 in basal cell carcinomas
    • Teh MT, Wong ST, Neill GW, et al. FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res. 2002;62(16):4773-4780.
    • (2002) Cancer Res , vol.62 , Issue.16 , pp. 4773-4780
    • Teh, M.T.1    Wong, S.T.2    Neill, G.W.3
  • 104
    • 11144280578 scopus 로고    scopus 로고
    • Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
    • Pilarsky C, Wenzig M, Specht T, et al. Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia. 2004;6(6):744-750.
    • (2004) Neoplasia , vol.6 , Issue.6 , pp. 744-750
    • Pilarsky, C.1    Wenzig, M.2    Specht, T.3
  • 105
    • 0031573921 scopus 로고    scopus 로고
    • The human TRIDENT/HFH-11/FKHL16 gene: Structure, localization, and promoter characterization
    • Korver W, Roose J, Heinen K, et al. The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization. Genomics. 1997;46(3):435-442.
    • (1997) Genomics , vol.46 , Issue.3 , pp. 435-442
    • Korver, W.1    Roose, J.2    Heinen, K.3
  • 106
    • 11144353897 scopus 로고    scopus 로고
    • Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
    • Kalinichenko W, Major ML, Wang X, et al. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev. 2004;18(7):830-850.
    • (2004) Genes Dev , vol.18 , Issue.7 , pp. 830-850
    • Kalinichenko, W.1    Major, M.L.2    Wang, X.3
  • 107
    • 0037438590 scopus 로고    scopus 로고
    • Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: An anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10
    • Berrebi D, Bruscoli S, Cohen N, et al. Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. Blood. 2003;101(2):729-738.
    • (2003) Blood , vol.101 , Issue.2 , pp. 729-738
    • Berrebi, D.1    Bruscoli, S.2    Cohen, N.3
  • 108
    • 0035437169 scopus 로고    scopus 로고
    • Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB
    • Ayroldi E, Migliorati G, Bruscoli S, et al. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. Blood. 2001;98(3):743-753.
    • (2001) Blood , vol.98 , Issue.3 , pp. 743-753
    • Ayroldi, E.1    Migliorati, G.2    Bruscoli, S.3
  • 109
    • 3042792367 scopus 로고    scopus 로고
    • GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis
    • Asselin-Labat ML, David M, Biola-Vidamment A, et al. GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis. Blood. 2004;104(1):215-223.
    • (2004) Blood , vol.104 , Issue.1 , pp. 215-223
    • Asselin-Labat, M.L.1    David, M.2    Biola-Vidamment, A.3
  • 110
    • 16444378654 scopus 로고    scopus 로고
    • Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of hedgehog signaling on pancreatic ductal epithelial cells
    • Prasad NB, Biankin AV, Fukushima N, et al. Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res. 2005;65(5):1619-1626.
    • (2005) Cancer Res , vol.65 , Issue.5 , pp. 1619-1626
    • Prasad, N.B.1    Biankin, A.V.2    Fukushima, N.3
  • 111
    • 0031683165 scopus 로고    scopus 로고
    • Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus
    • Motoyama J, Liu J, Mo R, et al. Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat Genet. 1998;20(1):54-57.
    • (1998) Nat Genet , vol.20 , Issue.1 , pp. 54-57
    • Motoyama, J.1    Liu, J.2    Mo, R.3
  • 112
    • 0030601955 scopus 로고    scopus 로고
    • Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development
    • Marigo V, Johnson RL, Vortkamp A, et al. Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development. Dev Biol. 1996;180(1):273-283.
    • (1996) Dev Biol , vol.180 , Issue.1 , pp. 273-283
    • Marigo, V.1    Johnson, R.L.2    Vortkamp, A.3
  • 113
    • 1942518374 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation
    • Vijapurkar U, Fischbach N, Shen W, et al. Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation. Mol Cell Biol. 2004;24(9):3827-3837.
    • (2004) Mol Cell Biol , vol.24 , Issue.9 , pp. 3827-3837
    • Vijapurkar, U.1    Fischbach, N.2    Shen, W.3
  • 114
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • Cheng W, Liu J, Yoshida H, et al. Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat Med. 2005;11(5):531-537.
    • (2005) Nat Med , vol.11 , Issue.5 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3
  • 115
    • 0022386613 scopus 로고
    • Expression of insulin-like growth factor-II transcripts in Wilms' tumour
    • Reeve AE, Eccles MR, Wilkins RJ, et al. Expression of insulin-like growth factor-II transcripts in Wilms' tumour. Nature. 1985;317(6034):258-260.
    • (1985) Nature , vol.317 , Issue.6034 , pp. 258-260
    • Reeve, A.E.1    Eccles, M.R.2    Wilkins, R.J.3
  • 116
    • 0032189403 scopus 로고    scopus 로고
    • Enhanced expression of the insulin receptor substrate-2 docking protein in human pancreatic cancer
    • Kornmann M, Maruyama H, Bergmann U, et al. Enhanced expression of the insulin receptor substrate-2 docking protein in human pancreatic cancer. Cancer Res. 1998;58(19):4250-4254.
    • (1998) Cancer Res , vol.58 , Issue.19 , pp. 4250-4254
    • Kornmann, M.1    Maruyama, H.2    Bergmann, U.3
  • 117
    • 0035012213 scopus 로고    scopus 로고
    • Insulin-like growth factor-II in endocrine pancreatic tumours. Immunohistochemical, biochemical and in situ hybridization findings
    • Hoog A, Kjellman M, Nordqvist AC, et al. Insulin-like growth factor-II in endocrine pancreatic tumours. Immunohistochemical, biochemical and in situ hybridization findings. Apmis. 2001;109(2):127-140.
    • (2001) Apmis , vol.109 , Issue.2 , pp. 127-140
    • Hoog, A.1    Kjellman, M.2    Nordqvist, A.C.3
  • 118
    • 0026669131 scopus 로고
    • Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1
    • Drummond IA, Madden SL, Rohwer-Nutter P, et al. Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science. 1992;257(5070):674-678.
    • (1992) Science , vol.257 , Issue.5070 , pp. 674-678
    • Drummond, I.A.1    Madden, S.L.2    Rohwer-Nutter, P.3
  • 119
    • 0035094925 scopus 로고    scopus 로고
    • Hedgehog signaling regulation of homeodomain protein islet duodenum homeobox-1 expression in pancreatic beta-cells
    • Thomas MK, Lee JH, Rastalsky N, et al. Hedgehog signaling regulation of homeodomain protein islet duodenum homeobox-1 expression in pancreatic beta-cells. Endocrinology. 2001;142(3):1033-1040.
    • (2001) Endocrinology , vol.142 , Issue.3 , pp. 1033-1040
    • Thomas, M.K.1    Lee, J.H.2    Rastalsky, N.3
  • 120
    • 0030907390 scopus 로고    scopus 로고
    • Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
    • Sharma S, Jhala US, Johnson T, et al. Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1. Mol Cell Biol. 1997;17(5):2598-2604.
    • (1997) Mol Cell Biol , vol.17 , Issue.5 , pp. 2598-2604
    • Sharma, S.1    Jhala, U.S.2    Johnson, T.3
  • 121
    • 0032103208 scopus 로고    scopus 로고
    • Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus
    • Seufert J, Weir GC, Habener JF. Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus. J Clin Invest. 1998;101(11):2528-2539.
    • (1998) J Clin Invest , vol.101 , Issue.11 , pp. 2528-2539
    • Seufert, J.1    Weir, G.C.2    Habener, J.F.3
  • 122
    • 0034649608 scopus 로고    scopus 로고
    • Attenuation of FGF signalling in mouse beta-cells leads to diabetes
    • Hart AW, Baeza N, Apelqvist A, et al. Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature. 2000;408(6814):864-868.
    • (2000) Nature , vol.408 , Issue.6814 , pp. 864-868
    • Hart, A.W.1    Baeza, N.2    Apelqvist, A.3
  • 123
    • 0031985396 scopus 로고    scopus 로고
    • A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus
    • Habener JF, Stoffers DA. A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus. Proc Assoc Am Phys. 1998;110(1):12-21.
    • (1998) Proc Assoc Am Phys , vol.110 , Issue.1 , pp. 12-21
    • Habener, J.F.1    Stoffers, D.A.2
  • 124
    • 0028277885 scopus 로고
    • Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism
    • corrected
    • Tanizawa Y, Riggs AC, Dagogo-Jack S, et al. Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism. Diabetes. 1994;43(7):935-941. [corrected].
    • (1994) Diabetes , vol.43 , Issue.7 , pp. 935-941
    • Tanizawa, Y.1    Riggs, A.C.2    Dagogo-Jack, S.3
  • 125
    • 0033856122 scopus 로고    scopus 로고
    • Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history
    • Shimomura H, Sanke T, Hanabusa T, et al. Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history. Diabetes. 2000;49(9):1597-1600.
    • (2000) Diabetes , vol.49 , Issue.9 , pp. 1597-1600
    • Shimomura, H.1    Sanke, T.2    Hanabusa, T.3
  • 126
    • 13544272476 scopus 로고    scopus 로고
    • Postnatal isl1 + cardioblasts enter fully differentiated cardiomyocyte lineages
    • Laugwitz KL, Moretti A, Lam J, et al. Postnatal isl1 + cardioblasts enter fully differentiated cardiomyocyte lineages. Nature. 2005;433(7026):647-653.
    • (2005) Nature , vol.433 , Issue.7026 , pp. 647-653
    • Laugwitz, K.L.1    Moretti, A.2    Lam, J.3
  • 127
    • 0029149178 scopus 로고
    • Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17
    • Tomasetto C, Reigner C, Moog-Lutz C, et al. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics. 1995;28(3):367-376.
    • (1995) Genomics , vol.28 , Issue.3 , pp. 367-376
    • Tomasetto, C.1    Reigner, C.2    Moog-Lutz, C.3
  • 128
    • 0345158295 scopus 로고    scopus 로고
    • Medaka spalt acts as a target gene of hedgehog signaling
    • Koster R, Stick R, Loosli F, et al. Medaka spalt acts as a target gene of hedgehog signaling. Development. 1997;124(16):3147-3156.
    • (1997) Development , vol.124 , Issue.16 , pp. 3147-3156
    • Koster, R.1    Stick, R.2    Loosli, F.3
  • 129
    • 0030589604 scopus 로고    scopus 로고
    • Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt
    • Kohlhase J, Schuh R, Dowe G, et al. Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics. 1996;38(3):291-298.
    • (1996) Genomics , vol.38 , Issue.3 , pp. 291-298
    • Kohlhase, J.1    Schuh, R.2    Dowe, G.3
  • 130
    • 0029921469 scopus 로고    scopus 로고
    • High-resolution mapping of a 130-kb core region of the MYCN amplicon in neuroblastomas
    • Reiter JL, Brodeur GM. High-resolution mapping of a 130-kb core region of the MYCN amplicon in neuroblastomas. Genomics. 1996;32(1):97-103.
    • (1996) Genomics , vol.32 , Issue.1 , pp. 97-103
    • Reiter, J.L.1    Brodeur, G.M.2
  • 131
    • 0037127290 scopus 로고    scopus 로고
    • HuD, a neuronal-specific RNA-binding protein, increases the in vivo stability of MYCN RNA
    • Manohar CF, Short ML, Nguyen A, et al. HuD, a neuronal-specific RNA-binding protein, increases the in vivo stability of MYCN RNA. J Biol Chem. 2002;277(3):1967-1973.
    • (2002) J Biol Chem , vol.277 , Issue.3 , pp. 1967-1973
    • Manohar, C.F.1    Short, M.L.2    Nguyen, A.3
  • 132
    • 0037232580 scopus 로고    scopus 로고
    • Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
    • Kenney AM, Cole MD, Rowitch DH. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development. 2003;130(1):15-28.
    • (2003) Development , vol.130 , Issue.1 , pp. 15-28
    • Kenney, A.M.1    Cole, M.D.2    Rowitch, D.H.3
  • 133
    • 0027729729 scopus 로고
    • MyoD or Myf-5 is required for the formation of skeletal muscle
    • Rudnicki MA, Schnegelsberg PN, Stead RH, et al. MyoD or Myf-5 is required for the formation of skeletal muscle. Cell. 1993;75(7):1351-1359.
    • (1993) Cell , vol.75 , Issue.7 , pp. 1351-1359
    • Rudnicki, M.A.1    Schnegelsberg, P.N.2    Stead, R.H.3
  • 134
    • 0025805798 scopus 로고
    • Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo
    • Ott MO, Bober E, Lyons G, et al. Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo. Development. 1991;111(4):1097-1107.
    • (1991) Development , vol.111 , Issue.4 , pp. 1097-1107
    • Ott, M.O.1    Bober, E.2    Lyons, G.3
  • 135
    • 0036142566 scopus 로고    scopus 로고
    • Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification
    • Gustafsson MK, Pan H, Pinney DF, et al. Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification. Genes Dev. 2002;16(1):114-126.
    • (2002) Genes Dev , vol.16 , Issue.1 , pp. 114-126
    • Gustafsson, M.K.1    Pan, H.2    Pinney, D.F.3
  • 136
    • 0032933175 scopus 로고    scopus 로고
    • Pax3 functions in cell survival and in pax7 regulation
    • Borycki AG, Li J, Jin F, et al. Pax3 functions in cell survival and in pax7 regulation. Development. 1999;126(8):1665-1674.
    • (1999) Development , vol.126 , Issue.8 , pp. 1665-1674
    • Borycki, A.G.1    Li, J.2    Jin, F.3
  • 137
    • 0032819250 scopus 로고    scopus 로고
    • Sonic hedgehog controls epaxial muscle determination through Myf5 activation
    • Borycki AG, Brunk B. Tajbakhsh S, et al. Sonic hedgehog controls epaxial muscle determination through Myf5 activation. Development. 1999;126(18):4053-4063.
    • (1999) Development , vol.126 , Issue.18 , pp. 4053-4063
    • Borycki, A.G.1    Brunk, B.2    Tajbakhsh, S.3
  • 138
    • 0041853572 scopus 로고    scopus 로고
    • Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog
    • Thibert C, Teillet MA, Lapointe F, et al. Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog. Science. 2003;301(5634):843-846.
    • (2003) Science , vol.301 , Issue.5634 , pp. 843-846
    • Thibert, C.1    Teillet, M.A.2    Lapointe, F.3
  • 139
    • 0037158748 scopus 로고    scopus 로고
    • Patched acts catalytically to suppress the activity of smoothened
    • Taipale J, Cooper MK, Maiti T, et al. Patched acts catalytically to suppress the activity of smoothened. Nature. 2002;418(6900):892-897.
    • (2002) Nature , vol.418 , Issue.6900 , pp. 892-897
    • Taipale, J.1    Cooper, M.K.2    Maiti, T.3
  • 140
    • 15244362560 scopus 로고    scopus 로고
    • Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons
    • Nagao K, Toyoda M, Takeuchi-Inoue K, et al. Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons. Genomics. 2005;85(4):462-471.
    • (2005) Genomics , vol.85 , Issue.4 , pp. 462-471
    • Nagao, K.1    Toyoda, M.2    Takeuchi-Inoue, K.3
  • 141
    • 0029278749 scopus 로고
    • Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing
    • Ingham PW, Fietz MJ. Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing. Curr Biol. 1995;5(4):432-440.
    • (1995) Curr Biol , vol.5 , Issue.4 , pp. 432-440
    • Ingham, P.W.1    Fietz, M.J.2
  • 142
    • 0025942098 scopus 로고
    • Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene
    • Spreyer P, Kuhn G, Hanemann CO, et al. Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene. EMBO J. 1991;10(12):3661-3668.
    • (1991) EMBO J , vol.10 , Issue.12 , pp. 3661-3668
    • Spreyer, P.1    Kuhn, G.2    Hanemann, C.O.3
  • 143
    • 0026519132 scopus 로고
    • Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13)
    • Snipes GJ, Suter U, Welcher AA, et al. Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13). J Cell Biol. 1992;117(1):225-238.
    • (1992) J Cell Biol , vol.117 , Issue.1 , pp. 225-238
    • Snipes, G.J.1    Suter, U.2    Welcher, A.A.3
  • 144
    • 0026907301 scopus 로고
    • Isolation and mapping to 17p12-13 of the human homologous of the murine growth arrest specific Gas-3 gene
    • Martinotti A, Cariani CT, Melani C, et al. Isolation and mapping to 17p12-13 of the human homologous of the murine growth arrest specific Gas-3 gene. Hum Mol Genet. 1992;1(5):331-334.
    • (1992) Hum Mol Genet , vol.1 , Issue.5 , pp. 331-334
    • Martinotti, A.1    Cariani, C.T.2    Melani, C.3
  • 145
    • 21544434328 scopus 로고    scopus 로고
    • Expression analysis of PMP22/Gas3 in pre-malignant and malignant pancreatic lesions
    • Li J, Kleeff J, Esposito I, et al. Expression analysis of PMP22/Gas3 in pre-malignant and malignant pancreatic lesions. J Histochem Cytochem. 2005;53:885.
    • (2005) J Histochem Cytochem , vol.53 , pp. 885
    • Li, J.1    Kleeff, J.2    Esposito, I.3
  • 146
    • 0035035010 scopus 로고    scopus 로고
    • Absence of functional type 1 parathyroid hormone (PTH)/PTH-related protein receptors in humans is associated with abnormal breast development and tooth impaction
    • Wysolmerski JJ, Cormier S, Philbrick WM, et al. Absence of functional type 1 parathyroid hormone (PTH)/PTH-related protein receptors in humans is associated with abnormal breast development and tooth impaction. J Clin Endocrinol Metab. 2001;86(4):1788-1794.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.4 , pp. 1788-1794
    • Wysolmerski, J.J.1    Cormier, S.2    Philbrick, W.M.3
  • 147
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • Vortkamp A, Lee K, Lanske B, et al. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 1996;273(5275):613-622.
    • (1996) Science , vol.273 , Issue.5275 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3
  • 148
    • 0034688213 scopus 로고    scopus 로고
    • The physiology of parathyroid hormone-related protein
    • Strewler GJ. The physiology of parathyroid hormone-related protein. N Engl J Med. 2000;342(3):177-185.
    • (2000) N Engl J Med , vol.342 , Issue.3 , pp. 177-185
    • Strewler, G.J.1
  • 149
    • 0025917701 scopus 로고
    • Parathyroid hormone-related peptide mediates hypercalcemia in an islet cell tumor of the pancreas
    • Mitlak BH, Hutchison JS, Kaufman SD, et al. Parathyroid hormone-related peptide mediates hypercalcemia in an islet cell tumor of the pancreas. Horm Metab Res. 1991;23(7):344-346.
    • (1991) Horm Metab Res , vol.23 , Issue.7 , pp. 344-346
    • Mitlak, B.H.1    Hutchison, J.S.2    Kaufman, S.D.3
  • 150
    • 0028133234 scopus 로고
    • A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice
    • Holick MF, Ray S, Chen TC, et al. A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice. Proc Natl Acad Sci USA. 1994;91(17):8014-8016.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.17 , pp. 8014-8016
    • Holick, M.F.1    Ray, S.2    Chen, T.C.3
  • 151
    • 0031024785 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein-(1-36) is biologically active when administered subcutaneously to humans
    • Henry JG, Mitnick M, Dann PR, et al. Parathyroid hormone-related protein-(1-36) is biologically active when administered subcutaneously to humans. J Clin Endocrinol Metab. 1997;82(3):900-906.
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.3 , pp. 900-906
    • Henry, J.G.1    Mitnick, M.2    Dann, P.R.3
  • 152
    • 0024415281 scopus 로고
    • The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas
    • Drucker DJ, Asa SL, Henderson J, et al. The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas. Mol Endocrinol. 1989;3(10):1589-1595.
    • (1989) Mol Endocrinol , vol.3 , Issue.10 , pp. 1589-1595
    • Drucker, D.J.1    Asa, S.L.2    Henderson, J.3
  • 153
    • 0036734144 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide is a naturally occurring protein kinase A-dependent angiogenesis inhibitor
    • Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002;8(9):995-1003.
    • (2002) Nat Med , vol.8 , Issue.9 , pp. 995-1003
    • Bakre, M.M.1    Zhu, Y.2    Yin, H.3
  • 154
    • 0033764030 scopus 로고    scopus 로고
    • Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers
    • Jacobs JJ, Keblusek P, Robanus-Maandag E, et al. Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers. Nat Genet. 2000;26(3):291-299.
    • (2000) Nat Genet , vol.26 , Issue.3 , pp. 291-299
    • Jacobs, J.J.1    Keblusek, P.2    Robanus-Maandag, E.3
  • 155
    • 0031903568 scopus 로고    scopus 로고
    • Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development
    • Gibson-Brown JJ, Agulnik SI, Silver LM, et al. Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. Development. 1998;125(13):2499-2509.
    • (1998) Development , vol.125 , Issue.13 , pp. 2499-2509
    • Gibson-Brown, J.J.1    Agulnik, S.I.2    Silver, L.M.3
  • 156
    • 0030466287 scopus 로고    scopus 로고
    • Pericardial mesothelioma secreting thrombomodulin
    • Okura Y, Kato K, Hanawa H, et al. Pericardial mesothelioma secreting thrombomodulin. Am Heart J. 1996;132(6):1309-1311.
    • (1996) Am Heart J , vol.132 , Issue.6 , pp. 1309-1311
    • Okura, Y.1    Kato, K.2    Hanawa, H.3
  • 157
    • 4644259231 scopus 로고    scopus 로고
    • The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value
    • Iino S, Abeyama K, Kawahara K, et al. The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value. Clin Cancer Res. 2004;10(18 Pt 1):6179-6188.
    • (2004) Clin Cancer Res , vol.10 , Issue.18 PART 1 , pp. 6179-6188
    • Iino, S.1    Abeyama, K.2    Kawahara, K.3
  • 158
    • 0034880422 scopus 로고    scopus 로고
    • Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis
    • Reddy S, Andl T, Bagasra A, et al. Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001;107(1-2):69-82.
    • (2001) Mech Dev , vol.107 , Issue.1-2 , pp. 69-82
    • Reddy, S.1    Andl, T.2    Bagasra, A.3
  • 159
    • 0035504739 scopus 로고    scopus 로고
    • Gene expression profiles of pancreatic cancer and stromal desmoplasia
    • Crnogorac-Jurcevic T, Efthimiou E, Capelli P, et al. Gene expression profiles of pancreatic cancer and stromal desmoplasia. Oncogene. 2001;20(50):7437-7446.
    • (2001) Oncogene , vol.20 , Issue.50 , pp. 7437-7446
    • Crnogorac-Jurcevic, T.1    Efthimiou, E.2    Capelli, P.3
  • 160
    • 0033051880 scopus 로고    scopus 로고
    • Evaluation of gonadal function in 107 intersex patients by means of serum antimullerian hormone measurement
    • Rey RA, Belville C, Nihoul-Fekete C, et al. Evaluation of gonadal function in 107 intersex patients by means of serum antimullerian hormone measurement. J Clin Endocrinol Metab. 1999;84(2):627-631.
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.2 , pp. 627-631
    • Rey, R.A.1    Belville, C.2    Nihoul-Fekete, C.3
  • 161
    • 0029658831 scopus 로고    scopus 로고
    • Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation
    • Mishina Y, Rey R, Finegold MJ, et al. Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev. 1996;10(20):2577-2587.
    • (1996) Genes Dev , vol.10 , Issue.20 , pp. 2577-2587
    • Mishina, Y.1    Rey, R.2    Finegold, M.J.3
  • 162
    • 0032543352 scopus 로고    scopus 로고
    • Tissue restricted expression of two human Frzbs in preadipocytes and pancreas
    • Hu E, Zhu Y, Fredrickson T, et al. Tissue restricted expression of two human Frzbs in preadipocytes and pancreas. Biochem Biophys Res Commun. 1998;247(2):287-293.
    • (1998) Biochem Biophys Res Commun , vol.247 , Issue.2 , pp. 287-293
    • Hu, E.1    Zhu, Y.2    Fredrickson, T.3
  • 163
    • 0034554849 scopus 로고    scopus 로고
    • Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice
    • Kubota T, Kawano S, Chih DY, et al. Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice. Blood. 2000;96(12):3953-3957.
    • (2000) Blood , vol.96 , Issue.12 , pp. 3953-3957
    • Kubota, T.1    Kawano, S.2    Chih, D.Y.3
  • 164
    • 1842535903 scopus 로고    scopus 로고
    • Shutting down Wnt signal-activated cancer
    • Taketo MM. Shutting down Wnt signal-activated cancer. Nat Genet. 2004;36(4):320-322.
    • (2004) Nat Genet , vol.36 , Issue.4 , pp. 320-322
    • Taketo, M.M.1
  • 165
    • 12144291274 scopus 로고    scopus 로고
    • Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
    • Suzuki H, Watkins DN, Jair KW, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet. 2004;36(4):417-422.
    • (2004) Nat Genet , vol.36 , Issue.4 , pp. 417-422
    • Suzuki, H.1    Watkins, D.N.2    Jair, K.W.3
  • 166
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • Suzuki H, Gabrielson E, Chen W, et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet. 2002;31(2):141-149.
    • (2002) Nat Genet , vol.31 , Issue.2 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3
  • 167
    • 0344740017 scopus 로고    scopus 로고
    • Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas
    • Heller RS, Klein T, Ling Z, et al. Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas. Gene Expr. 2003;11(3-4):141-147.
    • (2003) Gene Expr , vol.11 , Issue.3-4 , pp. 141-147
    • Heller, R.S.1    Klein, T.2    Ling, Z.3
  • 168
    • 0036277973 scopus 로고    scopus 로고
    • Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity
    • Fukuhara K, Kariya M, Kita M, et al. Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity. J Clin Endocrinol Metab. 2002;87(4):1729-1736.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.4 , pp. 1729-1736
    • Fukuhara, K.1    Kariya, M.2    Kita, M.3
  • 169
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myohanen S, et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet. 1999;21(1):103-107.
    • (1999) Nat Genet , vol.21 , Issue.1 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3
  • 170
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet. 2000;16(4):168-174.
    • (2000) Trends Genet , vol.16 , Issue.4 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.