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Volumn 114, Issue , 2012, Pages 151-176

Enhancing Cancer Immunotherapy by Intracellular Delivery of Cell-Penetrating Peptides and Stimulation of Pattern-Recognition Receptor Signaling

Author keywords

Cancer vaccines; Cell penetrating peptides; Immunological intervention; Immunotherapy; Innate immune signaling

Indexed keywords

CELL PENETRATING PEPTIDE; CYCLOPHOSPHAMIDE; FLUDARABINE; GLYCOPROTEIN GP 100; HLA DR ANTIGEN; HLA DR4 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELANOMA ANTIGEN 3; MONOPHENOL MONOOXYGENASE; MYELOID DIFFERENTIATION FACTOR 88; NY ESO 1 ANTIGEN; SIPULEUCEL T; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR 8; TUMOR ANTIGEN;

EID: 84863354483     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/B978-0-12-396548-6.00006-8     Document Type: Chapter
Times cited : (26)

References (170)
  • 1
    • 0033010380 scopus 로고    scopus 로고
    • Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1
    • Aarnoudse C.A., van den Doel P.B., Heemskerk B., Schrier P.I. Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1. Int. J. Cancer 1999, 82:442-448.
    • (1999) Int. J. Cancer , vol.82 , pp. 442-448
    • Aarnoudse, C.A.1    van den Doel, P.B.2    Heemskerk, B.3    Schrier, P.I.4
  • 2
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 6
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature 1998, 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 7
    • 0345016358 scopus 로고    scopus 로고
    • Identification of five new HLA-B*3501-restricted epitopes derived from common melanoma-associated antigens, spontaneously recognized by tumor-infiltrating lymphocytes
    • Benlalam H., Linard B., Guilloux Y., Moreau-Aubry A., Derre L., Diez E., Dreno B., Jotereau F., Labarriere N. Identification of five new HLA-B*3501-restricted epitopes derived from common melanoma-associated antigens, spontaneously recognized by tumor-infiltrating lymphocytes. J. Immunol. 2003, 171:6283-6289.
    • (2003) J. Immunol. , vol.171 , pp. 6283-6289
    • Benlalam, H.1    Linard, B.2    Guilloux, Y.3    Moreau-Aubry, A.4    Derre, L.5    Diez, E.6    Dreno, B.7    Jotereau, F.8    Labarriere, N.9
  • 8
    • 45149126142 scopus 로고    scopus 로고
    • Intracellular delivery of nanoparticles via the HIV-1 tat peptide
    • Berry C.C. Intracellular delivery of nanoparticles via the HIV-1 tat peptide. Nanomedicine 2008, 3:357-365.
    • (2008) Nanomedicine , vol.3 , pp. 357-365
    • Berry, C.C.1
  • 10
    • 84870242257 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines: The latest advancement in targeted therapy
    • In Press (Epublication Feb. 2011)
    • Bilusic M., Madan R.A. Therapeutic cancer vaccines: The latest advancement in targeted therapy. Am. J. Ther 2011, In Press (Epublication Feb. 2011).
    • (2011) Am. J. Ther
    • Bilusic, M.1    Madan, R.A.2
  • 13
    • 0030048081 scopus 로고    scopus 로고
    • A tyrosinase nonpeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes
    • Brichard V.G., Herman J., Van Pel A., Wildmann C., Gaugler B., Wolfel T., Boon T., Lethe B. A tyrosinase nonpeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes. Eur. J. Immunol. 1996, 26:224-230.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 224-230
    • Brichard, V.G.1    Herman, J.2    Van Pel, A.3    Wildmann, C.4    Gaugler, B.5    Wolfel, T.6    Boon, T.7    Lethe, B.8
  • 14
    • 78449243490 scopus 로고    scopus 로고
    • Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy
    • Callahan M.K., Wolchok J.D., Allison J.P. Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy. Semin. Oncol. 2010, 37:473-484.
    • (2010) Semin. Oncol. , vol.37 , pp. 473-484
    • Callahan, M.K.1    Wolchok, J.D.2    Allison, J.P.3
  • 18
    • 0035056017 scopus 로고    scopus 로고
    • CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
    • Chambers C.A., Kuhns M.S., Egen J.G., Allison J.P. CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy. Annu. Rev. Immunol. 2001, 19:565-594.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 565-594
    • Chambers, C.A.1    Kuhns, M.S.2    Egen, J.G.3    Allison, J.P.4
  • 19
    • 0033198114 scopus 로고    scopus 로고
    • Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1
    • Chaux P., Luiten R., Demotte N., Vantomme V., Stroobant V., Traversari C., Russo V., Schultz E., Cornelis G.R., Boon T., et al. Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1. J. Immunol. 1999, 163:2928-2936.
    • (1999) J. Immunol. , vol.163 , pp. 2928-2936
    • Chaux, P.1    Luiten, R.2    Demotte, N.3    Vantomme, V.4    Stroobant, V.5    Traversari, C.6    Russo, V.7    Schultz, E.8    Cornelis, G.R.9    Boon, T.10
  • 22
    • 0034282516 scopus 로고    scopus 로고
    • Identification of a tumor-specific shared antigen derived from an Eph receptor and presented to CD4 T cells on HLA class II molecules
    • Chiari R., Hames G., Stroobant V., Texier C., Maillere B., Boon T., Coulie P.G. Identification of a tumor-specific shared antigen derived from an Eph receptor and presented to CD4 T cells on HLA class II molecules. Cancer Res. 2000, 60:4855-4863.
    • (2000) Cancer Res. , vol.60 , pp. 4855-4863
    • Chiari, R.1    Hames, G.2    Stroobant, V.3    Texier, C.4    Maillere, B.5    Boon, T.6    Coulie, P.G.7
  • 25
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 29
    • 79952438607 scopus 로고    scopus 로고
    • Harnessing dendritic cells for immunotherapy
    • Delamarre L., Mellman I. Harnessing dendritic cells for immunotherapy. Semin. Immunol. 2011, 23:2-11.
    • (2011) Semin. Immunol. , vol.23 , pp. 2-11
    • Delamarre, L.1    Mellman, I.2
  • 30
    • 23944483437 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
    • Deshayes S., Morris M.C., Divita G., Heitz F. Cell-penetrating peptides: Tools for intracellular delivery of therapeutics. Cell. Mol. Life Sci. 2005, 62:1839-1849.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 1839-1849
    • Deshayes, S.1    Morris, M.C.2    Divita, G.3    Heitz, F.4
  • 31
    • 0034895155 scopus 로고    scopus 로고
    • Strategies for target cell recognition by natural killer cells
    • Diefenbach A., Raulet D.H. Strategies for target cell recognition by natural killer cells. Immunol. Rev. 2001, 181:170-184.
    • (2001) Immunol. Rev. , vol.181 , pp. 170-184
    • Diefenbach, A.1    Raulet, D.H.2
  • 34
    • 78650576197 scopus 로고    scopus 로고
    • Use of defined TLR ligands as adjuvants within human vaccines
    • Duthie M.S., Windish H.P., Fox C.B., Reed S.G. Use of defined TLR ligands as adjuvants within human vaccines. Immunol. Rev. 2011, 239:178-196.
    • (2011) Immunol. Rev. , vol.239 , pp. 178-196
    • Duthie, M.S.1    Windish, H.P.2    Fox, C.B.3    Reed, S.G.4
  • 35
    • 59849102702 scopus 로고    scopus 로고
    • Protein transduction revisited: Novel insights into the mechanism underlying intracellular delivery of proteins
    • Edenhofer F. Protein transduction revisited: Novel insights into the mechanism underlying intracellular delivery of proteins. Curr. Pharm. Des. 2008, 14:3628-3636.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 3628-3636
    • Edenhofer, F.1
  • 36
    • 0028104406 scopus 로고
    • Characterization of natural peptide ligands for HLA-B*4402 and -B*4403: Implications for peptide involvement in allorecognition of a single amino acid change in the HLA-B44 heavy chain
    • Fleischhauer K., Avila D., Vilbois F., Traversari C., Bordignon C., Wallny H.J. Characterization of natural peptide ligands for HLA-B*4402 and -B*4403: Implications for peptide involvement in allorecognition of a single amino acid change in the HLA-B44 heavy chain. Tissue Antigens 1995, 44:311-317.
    • (1995) Tissue Antigens , vol.44 , pp. 311-317
    • Fleischhauer, K.1    Avila, D.2    Vilbois, F.3    Traversari, C.4    Bordignon, C.5    Wallny, H.J.6
  • 37
    • 0033579910 scopus 로고    scopus 로고
    • A MAGE-1-encoded HLA-A24-binding synthetic peptide induces specific anti-tumor cytotoxic T lymphocytes
    • Fujie T., Tahara K., Tanaka F., Mori M., Takesako K., Akiyoshi T. A MAGE-1-encoded HLA-A24-binding synthetic peptide induces specific anti-tumor cytotoxic T lymphocytes. Int. J. Cancer 1999, 80:169-172.
    • (1999) Int. J. Cancer , vol.80 , pp. 169-172
    • Fujie, T.1    Tahara, K.2    Tanaka, F.3    Mori, M.4    Takesako, K.5    Akiyoshi, T.6
  • 39
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • Greenberg P.D. Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells. Adv. Immunol. 1991, 49:281-355.
    • (1991) Adv. Immunol. , vol.49 , pp. 281-355
    • Greenberg, P.D.1
  • 40
    • 0019951384 scopus 로고
    • Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes
    • Grimm E.A., Mazumder A., Zhang H.Z., Rosenberg S.A. Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. J. Exp. Med. 1982, 155:1823-1841.
    • (1982) J. Exp. Med. , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Mazumder, A.2    Zhang, H.Z.3    Rosenberg, S.A.4
  • 41
    • 13844298046 scopus 로고    scopus 로고
    • Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
    • Gupta B., Levchenko T.S., Torchilin V.P. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv. Drug Deliv. Rev. 2005, 57:637-651.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 637-651
    • Gupta, B.1    Levchenko, T.S.2    Torchilin, V.P.3
  • 42
    • 0034120928 scopus 로고    scopus 로고
    • Cytolytic T lymphocytes raised against a human bladder carcinoma recognize an antigen encoded by gene MAGE-A12
    • Heidecker L., Brasseur F., Probst-Kepper M., Gueguen M., Boon T., Van den Eynde B.J. Cytolytic T lymphocytes raised against a human bladder carcinoma recognize an antigen encoded by gene MAGE-A12. J. Immunol. 2000, 164:6041-6045.
    • (2000) J. Immunol. , vol.164 , pp. 6041-6045
    • Heidecker, L.1    Brasseur, F.2    Probst-Kepper, M.3    Gueguen, M.4    Boon, T.5    Van den Eynde, B.J.6
  • 45
    • 78751628167 scopus 로고    scopus 로고
    • Clinical trials on CIK cells: First report of the international registry on CIK cells (IRCC)
    • Hontscha C., Borck Y., Zhou H., Messmer D., Schmidt-Wolf I.G. Clinical trials on CIK cells: First report of the international registry on CIK cells (IRCC). J. Cancer Res. Clin. Oncol. 2011, 137:305-310.
    • (2011) J. Cancer Res. Clin. Oncol. , vol.137 , pp. 305-310
    • Hontscha, C.1    Borck, Y.2    Zhou, H.3    Messmer, D.4    Schmidt-Wolf, I.G.5
  • 47
    • 79953123163 scopus 로고    scopus 로고
    • Hepatitis B virus infection, its sequelae, and prevention by vaccination
    • Huang L.M., Lu C.Y., Chen D.S. Hepatitis B virus infection, its sequelae, and prevention by vaccination. Curr. Opin. Immunol. 2011, 23:237-243.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 237-243
    • Huang, L.M.1    Lu, C.Y.2    Chen, D.S.3
  • 49
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A., Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 2004, 5:987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 50
    • 2642683198 scopus 로고    scopus 로고
    • Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes
    • Jager E., Chen Y.T., Drijfhout J.W., Karbach J., Ringhoffer M., Jager D., Arand M., Wada H., Noguchi Y., Stockert E., et al. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes. J. Exp. Med. 1998, 187:265-270.
    • (1998) J. Exp. Med. , vol.187 , pp. 265-270
    • Jager, E.1    Chen, Y.T.2    Drijfhout, J.W.3    Karbach, J.4    Ringhoffer, M.5    Jager, D.6    Arand, M.7    Wada, H.8    Noguchi, Y.9    Stockert, E.10
  • 51
    • 24044554898 scopus 로고    scopus 로고
    • The efficacy of chemotherapy in combination with auto-cytokine-induced killer cells in acute leukemia
    • Jiang H., Liu K.Y., Tong C.R., Jiang B., Lu D.P. The efficacy of chemotherapy in combination with auto-cytokine-induced killer cells in acute leukemia. Zhonghua Nei Ke Za Zhi 2005, 44:198-201.
    • (2005) Zhonghua Nei Ke Za Zhi , vol.44 , pp. 198-201
    • Jiang, H.1    Liu, K.Y.2    Tong, C.R.3    Jiang, B.4    Lu, D.P.5
  • 53
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
    • Karin M., Lawrence T., Nizet V. Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer. Cell 2006, 124:823-835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 56
    • 0028302028 scopus 로고
    • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2 restricted tumor infiltrating lymphocytes
    • Kawakami Y., Eliyahu S., Sakaguchi K., Robbins P.F., Rivoltini L., Yannelli J.B., Appella E., Rosenberg S.A. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2 restricted tumor infiltrating lymphocytes. J. Exp. Med. 1994, 180:347-352.
    • (1994) J. Exp. Med. , vol.180 , pp. 347-352
    • Kawakami, Y.1    Eliyahu, S.2    Sakaguchi, K.3    Robbins, P.F.4    Rivoltini, L.5    Yannelli, J.B.6    Appella, E.7    Rosenberg, S.A.8
  • 58
    • 0032534587 scopus 로고    scopus 로고
    • Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, - A2, and -A3 alleles
    • Kawakami Y., Robbins P.F., Wang X., Tupesis J.P., Parkhurst M.R., Kang X., Sakaguchi K., Appella E., Rosenberg S.A. Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, - A2, and -A3 alleles. J. Immunol. 1998, 161:6985-6992.
    • (1998) J. Immunol. , vol.161 , pp. 6985-6992
    • Kawakami, Y.1    Robbins, P.F.2    Wang, X.3    Tupesis, J.P.4    Parkhurst, M.R.5    Kang, X.6    Sakaguchi, K.7    Appella, E.8    Rosenberg, S.A.9
  • 59
    • 0031755442 scopus 로고    scopus 로고
    • Identification of gp100-derived, melanoma-specific cytotoxic T- lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells
    • Kawashima I., Tsai V., Southwood S., Takesako K., Celis E., Sette A. Identification of gp100-derived, melanoma-specific cytotoxic T- lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells. Int. J. Cancer 1998, 78:518-524.
    • (1998) Int. J. Cancer , vol.78 , pp. 518-524
    • Kawashima, I.1    Tsai, V.2    Southwood, S.3    Takesako, K.4    Celis, E.5    Sette, A.6
  • 63
    • 0035887163 scopus 로고    scopus 로고
    • Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen
    • Kobayashi H., Lu J., Celis E. Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen. Cancer Res. 2001, 61:7577-7584.
    • (2001) Cancer Res. , vol.61 , pp. 7577-7584
    • Kobayashi, H.1    Lu, J.2    Celis, E.3
  • 64
    • 0035874608 scopus 로고    scopus 로고
    • Tumor-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles
    • Kobayashi H., Song Y., Hoon D.S., Appella E., Celis E. Tumor-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles. Cancer Res. 2001, 61:4773-4778.
    • (2001) Cancer Res. , vol.61 , pp. 4773-4778
    • Kobayashi, H.1    Song, Y.2    Hoon, D.S.3    Appella, E.4    Celis, E.5
  • 65
    • 79953104927 scopus 로고    scopus 로고
    • Prevention of cancer by prophylactic human papillomavirus vaccines
    • Kwak K., Yemelyanova A., Roden R.B. Prevention of cancer by prophylactic human papillomavirus vaccines. Curr. Opin. Immunol. 2011, 23:244-251.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 244-251
    • Kwak, K.1    Yemelyanova, A.2    Roden, R.B.3
  • 66
    • 0035887664 scopus 로고    scopus 로고
    • Retrovirally transduced human dendritic cells can generate T cells recognizing multiple MHC class I and class II epitopes from the melanoma antigen glycoprotein 100
    • Lapointe R., Royal R.E., Reeves M.E., Altomare I., Robbins P.F., Hwu P. Retrovirally transduced human dendritic cells can generate T cells recognizing multiple MHC class I and class II epitopes from the melanoma antigen glycoprotein 100. J. Immunol. 2001, 167:4758-4764.
    • (2001) J. Immunol. , vol.167 , pp. 4758-4764
    • Lapointe, R.1    Royal, R.E.2    Reeves, M.E.3    Altomare, I.4    Robbins, P.F.5    Hwu, P.6
  • 67
    • 0034892688 scopus 로고    scopus 로고
    • Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses
    • Leen A., Meij P., Redchenko I., Middeldorp J., Bloemena E., Rickinson A., Blake N. Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses. J. Virol. 2001, 75:8649-8659.
    • (2001) J. Virol. , vol.75 , pp. 8649-8659
    • Leen, A.1    Meij, P.2    Redchenko, I.3    Middeldorp, J.4    Bloemena, E.5    Rickinson, A.6    Blake, N.7
  • 68
    • 33749514632 scopus 로고    scopus 로고
    • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
    • Leen A.M., Myers G.D., Sili U., Huls M.H., Weiss H., Leung K.S., Carrum G., Krance R.A., Chang C.C., Molldrem J.J., et al. Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat. Med. 2006, 12:1160-1166.
    • (2006) Nat. Med. , vol.12 , pp. 1160-1166
    • Leen, A.M.1    Myers, G.D.2    Sili, U.3    Huls, M.H.4    Weiss, H.5    Leung, K.S.6    Carrum, G.7    Krance, R.A.8    Chang, C.C.9    Molldrem, J.J.10
  • 71
    • 0036162007 scopus 로고    scopus 로고
    • Generation of cytokine-induced killer cells from leukaemic samples with in vitro cytotoxicity against autologous and allogeneic leukaemic blasts
    • Linn Y.C., Lau L.C., Hui K.M. Generation of cytokine-induced killer cells from leukaemic samples with in vitro cytotoxicity against autologous and allogeneic leukaemic blasts. Br. J. Haematol. 2002, 116:78-86.
    • (2002) Br. J. Haematol. , vol.116 , pp. 78-86
    • Linn, Y.C.1    Lau, L.C.2    Hui, K.M.3
  • 72
    • 33646487278 scopus 로고    scopus 로고
    • Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells
    • Liu H., Komai-Koma M., Xu D., Liew F.Y. Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells. Proc. Natl. Acad. Sci. USA 2006, 103:7048-7053.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7048-7053
    • Liu, H.1    Komai-Koma, M.2    Xu, D.3    Liew, F.Y.4
  • 73
    • 79953068030 scopus 로고    scopus 로고
    • Immune defence against EBV and EBV-associated disease
    • Long H.M., Taylor G.S., Rickinson A.B. Immune defence against EBV and EBV-associated disease. Curr. Opin. Immunol. 2011, 23:258-264.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 258-264
    • Long, H.M.1    Taylor, G.S.2    Rickinson, A.B.3
  • 74
    • 0032555951 scopus 로고    scopus 로고
    • Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage
    • Lupetti R., Pisarra P., Verrecchia A., Farina C., Nicolini G., Anichini A., Bordignon C., Sensi M., Parmiani G., Traversari C. Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage. J. Exp. Med. 1998, 188:1005-1016.
    • (1998) J. Exp. Med. , vol.188 , pp. 1005-1016
    • Lupetti, R.1    Pisarra, P.2    Verrecchia, A.3    Farina, C.4    Nicolini, G.5    Anichini, A.6    Bordignon, C.7    Sensi, M.8    Parmiani, G.9    Traversari, C.10
  • 75
    • 0030800823 scopus 로고    scopus 로고
    • A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma
    • Mandruzzato S., Brasseur F., Andry G., Boon T., van der Bruggen P. A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. J. Exp. Med. 1997, 186:785-793.
    • (1997) J. Exp. Med. , vol.186 , pp. 785-793
    • Mandruzzato, S.1    Brasseur, F.2    Andry, G.3    Boon, T.4    van der Bruggen, P.5
  • 76
    • 69949083414 scopus 로고    scopus 로고
    • Modulation of adaptive immunity with Toll-like receptors
    • Manicassamy S., Pulendran B. Modulation of adaptive immunity with Toll-like receptors. Semin. Immunol. 2009, 21:185-193.
    • (2009) Semin. Immunol. , vol.21 , pp. 185-193
    • Manicassamy, S.1    Pulendran, B.2
  • 79
    • 0038280092 scopus 로고    scopus 로고
    • Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1
    • Marshall N.A., Vickers M.A., Barker R.N. Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1. J. Immunol. 2003, 170:6183-6189.
    • (2003) J. Immunol. , vol.170 , pp. 6183-6189
    • Marshall, N.A.1    Vickers, M.A.2    Barker, R.N.3
  • 80
    • 42549138499 scopus 로고    scopus 로고
    • Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines
    • Melief C.J., van der Burg S.H. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat. Rev. Cancer 2008, 8:351-360.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 351-360
    • Melief, C.J.1    van der Burg, S.H.2
  • 84
    • 0342647351 scopus 로고    scopus 로고
    • Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2
    • Noppen C., Levy F., Burri L., Zajac P., Remmel E., Schaefer C., Luscher U., Heberer M., Spagnoli G.C. Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2. Int. J. Cancer 2000, 87:241-246.
    • (2000) Int. J. Cancer , vol.87 , pp. 241-246
    • Noppen, C.1    Levy, F.2    Burri, L.3    Zajac, P.4    Remmel, E.5    Schaefer, C.6    Luscher, U.7    Heberer, M.8    Spagnoli, G.C.9
  • 85
    • 80052677833 scopus 로고    scopus 로고
    • TLR2 Stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function
    • Nyirenda M.H., Sanvito L., Darlington P.J., O'Brien K., Zhang G.X., Constantinescu C.S., Bar-Or A., Gran B. TLR2 Stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function. J. Immunol. 2011, 187:2278-2290.
    • (2011) J. Immunol. , vol.187 , pp. 2278-2290
    • Nyirenda, M.H.1    Sanvito, L.2    Darlington, P.J.3    O'Brien, K.4    Zhang, G.X.5    Constantinescu, C.S.6    Bar-Or, A.7    Gran, B.8
  • 86
    • 77954503874 scopus 로고    scopus 로고
    • Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands
    • Oberg H.H., Ly T.T., Ussat S., Meyer T., Kabelitz D., Wesch D. Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands. J. Immunol. 2010, 184:4733-4740.
    • (2010) J. Immunol. , vol.184 , pp. 4733-4740
    • Oberg, H.H.1    Ly, T.T.2    Ussat, S.3    Meyer, T.4    Kabelitz, D.5    Wesch, D.6
  • 88
    • 0038781722 scopus 로고    scopus 로고
    • CD4+ T cell responses in the immune control against latent infection by Epstein-Barr virus
    • Paludan C., Munz C. CD4+ T cell responses in the immune control against latent infection by Epstein-Barr virus. Curr. Mol. Med. 2003, 3:341-347.
    • (2003) Curr. Mol. Med. , vol.3 , pp. 341-347
    • Paludan, C.1    Munz, C.2
  • 89
    • 0034655180 scopus 로고    scopus 로고
    • A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12
    • Panelli M.C., Bettinotti M.P., Lally K., Ohnmacht G.A., Li Y., Robbins P., Riker A., Rosenberg S.A., Marincola F.M. A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12. J. Immunol. 2000, 164:4382-4392.
    • (2000) J. Immunol. , vol.164 , pp. 4382-4392
    • Panelli, M.C.1    Bettinotti, M.P.2    Lally, K.3    Ohnmacht, G.A.4    Li, Y.5    Robbins, P.6    Riker, A.7    Rosenberg, S.A.8    Marincola, F.M.9
  • 90
    • 0032212445 scopus 로고    scopus 로고
    • Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2)
    • Parkhurst M.R., Fitzgerald E.B., Southwood S., Sette A., Rosenberg S.A., Kawakami Y. Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2). Cancer Res. 1998, 58:4895-4901.
    • (1998) Cancer Res. , vol.58 , pp. 4895-4901
    • Parkhurst, M.R.1    Fitzgerald, E.B.2    Southwood, S.3    Sette, A.4    Rosenberg, S.A.5    Kawakami, Y.6
  • 92
    • 34548024379 scopus 로고    scopus 로고
    • Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway
    • Peng G., Wang H.Y., Peng W., Kiniwa Y., Seo K., Wang R.-F. Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway. Immunity 2007, 27:334-348.
    • (2007) Immunity , vol.27 , pp. 334-348
    • Peng, G.1    Wang, H.Y.2    Peng, W.3    Kiniwa, Y.4    Seo, K.5    Wang, R.-F.6
  • 93
    • 0035902067 scopus 로고    scopus 로고
    • Cancer epidemiology in the last century and the next decade
    • Peto J. Cancer epidemiology in the last century and the next decade. Nature 2001, 411:390-395.
    • (2001) Nature , vol.411 , pp. 390-395
    • Peto, J.1
  • 95
    • 0029669950 scopus 로고    scopus 로고
    • A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
    • Robbins P.F., El-Gamil M., Li Y.F., Kawakami Y., Loftus D., Appella E., Rosenberg S.A. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J. Exp. Med. 1996, 183:1185-1192.
    • (1996) J. Exp. Med. , vol.183 , pp. 1185-1192
    • Robbins, P.F.1    El-Gamil, M.2    Li, Y.F.3    Kawakami, Y.4    Loftus, D.5    Appella, E.6    Rosenberg, S.A.7
  • 96
    • 0031183901 scopus 로고    scopus 로고
    • The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes
    • Robbins P., El-Gamil M., Li Y.F., Fitzgerald E., Kawakami Y., Rosenberg S.A. The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes. J. Immunol. 1997, 159:303-308.
    • (1997) J. Immunol. , vol.159 , pp. 303-308
    • Robbins, P.1    El-Gamil, M.2    Li, Y.F.3    Fitzgerald, E.4    Kawakami, Y.5    Rosenberg, S.A.6
  • 97
    • 0025435083 scopus 로고
    • Adoptive immunotherapy for cancer
    • Rosenberg S.A. Adoptive immunotherapy for cancer. Sci. Am. 1990, 262:62-69.
    • (1990) Sci. Am. , vol.262 , pp. 62-69
    • Rosenberg, S.A.1
  • 98
    • 0033847583 scopus 로고    scopus 로고
    • Interleukin-2 and the development of immunotherapy for the treatment of patients with cancer
    • Rosenberg S.A. Interleukin-2 and the development of immunotherapy for the treatment of patients with cancer. Cancer J. Sci. Am. 2000, 6(Suppl. 1):S2-S7.
    • (2000) Cancer J. Sci. Am. , vol.6 , Issue.SUPPL. 1
    • Rosenberg, S.A.1
  • 99
    • 80053567512 scopus 로고    scopus 로고
    • Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know
    • Rosenberg S.A. Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know. Nat. Rev. Clin. Oncol. 2011, 8:577-585.
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 577-585
    • Rosenberg, S.A.1
  • 100
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
    • Rosenberg S.A., Lotze M.T., Muul L.M., Chang A.E., Avis F.P., Leitman S., Linehan W.M., Robertson C.N., Lee R.E., Rubin J.T., et al. A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. N. Engl. J. Med. 1987, 316:889-897.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3    Chang, A.E.4    Avis, F.P.5    Leitman, S.6    Linehan, W.M.7    Robertson, C.N.8    Lee, R.E.9    Rubin, J.T.10
  • 104
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg S.A., Yang J.C., Restifo N.P. Cancer immunotherapy: Moving beyond current vaccines. Nat. Med. 2004, 10:909-915.
    • (2004) Nat. Med. , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 107
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round J.L., Lee S.M., Li J., Tran G., Jabri B., Chatila T.A., Mazmanian S.K. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011, 332:974-977.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5    Chatila, T.A.6    Mazmanian, S.K.7
  • 110
    • 0025856106 scopus 로고
    • Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
    • Schmidt-Wolf I.G., Negrin R.S., Kiem H.P., Blume K.G., Weissman I.L. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J. Exp. Med. 1991, 174:139-149.
    • (1991) J. Exp. Med. , vol.174 , pp. 139-149
    • Schmidt-Wolf, I.G.1    Negrin, R.S.2    Kiem, H.P.3    Blume, K.G.4    Weissman, I.L.5
  • 111
    • 0032579240 scopus 로고    scopus 로고
    • Overlapping peptides of melanocyte differentiation antigen Melan-A/MART- 1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1
    • Schneider J., Brichard V., Boon T., Meyer zum Buschenfelde K.H., Wolfel T. Overlapping peptides of melanocyte differentiation antigen Melan-A/MART- 1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1. Int. J. Cancer 1998, 75:451-458.
    • (1998) Int. J. Cancer , vol.75 , pp. 451-458
    • Schneider, J.1    Brichard, V.2    Boon, T.3    Meyer zum Buschenfelde, K.H.4    Wolfel, T.5
  • 112
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber R.D., Old L.J., Smyth M.J. Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion. Science 2011, 331:1565-1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 113
    • 0036569585 scopus 로고    scopus 로고
    • Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells
    • Schroers R., Huang X.F., Hammer J., Zhang J., Chen S.Y. Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells. Cancer Res. 2002, 62:2600-2605.
    • (2002) Cancer Res. , vol.62 , pp. 2600-2605
    • Schroers, R.1    Huang, X.F.2    Hammer, J.3    Zhang, J.4    Chen, S.Y.5
  • 116
    • 0036024178 scopus 로고    scopus 로고
    • Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones
    • Sensi M., Pellegatta S., Vegetti C., Nicolini G., Parmiani G., Anichini A. Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones. Tissue Antigens 2002, 59:273-279.
    • (2002) Tissue Antigens , vol.59 , pp. 273-279
    • Sensi, M.1    Pellegatta, S.2    Vegetti, C.3    Nicolini, G.4    Parmiani, G.5    Anichini, A.6
  • 118
    • 0037307840 scopus 로고    scopus 로고
    • CD4+ Th2 cell recognition of HLA-DR-restricted epitopes derived from CAMEL: A tumor antigen translated in an alternative open reading frame
    • Slager E.H., Borghi M., van der Minne C.E., Aarnoudse C.A., Havenga M.J., Schrier P.I., Osanto S., Griffioen M. CD4+ Th2 cell recognition of HLA-DR-restricted epitopes derived from CAMEL: A tumor antigen translated in an alternative open reading frame. J. Immunol. 2003, 170:1490-1497.
    • (2003) J. Immunol. , vol.170 , pp. 1490-1497
    • Slager, E.H.1    Borghi, M.2    van der Minne, C.E.3    Aarnoudse, C.A.4    Havenga, M.J.5    Schrier, P.I.6    Osanto, S.7    Griffioen, M.8
  • 119
    • 40449128297 scopus 로고    scopus 로고
    • A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression
    • Song X.T., Evel-Kabler K., Shen L., Rollins L., Huang X.F., Chen S.Y. A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression. Nat. Med. 2008, 14:258-265.
    • (2008) Nat. Med. , vol.14 , pp. 258-265
    • Song, X.T.1    Evel-Kabler, K.2    Shen, L.3    Rollins, L.4    Huang, X.F.5    Chen, S.Y.6
  • 122
    • 79952440284 scopus 로고    scopus 로고
    • Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines
    • Tacken P.J., Figdor C.G. Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines. Semin. Immunol. 2011, 23:12-20.
    • (2011) Semin. Immunol. , vol.23 , pp. 12-20
    • Tacken, P.J.1    Figdor, C.G.2
  • 123
    • 0032792104 scopus 로고    scopus 로고
    • Identification of a MAGE-2-encoded human leukocyte antigen-A24-binding synthetic peptide that induces specific antitumor cytotoxic T lymphocytes
    • Tahara K., Takesako K., Sette A., Celis E., Kitano S., Akiyoshi T. Identification of a MAGE-2-encoded human leukocyte antigen-A24-binding synthetic peptide that induces specific antitumor cytotoxic T lymphocytes. Clin. Cancer Res. 1999, 5:2236-2241.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2236-2241
    • Tahara, K.1    Takesako, K.2    Sette, A.3    Celis, E.4    Kitano, S.5    Akiyoshi, T.6
  • 125
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K., Akira S. Toll-like receptors in innate immunity. Int. Immunol. 2005, 17:1-14.
    • (2005) Int. Immunol. , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 126
    • 0030871041 scopus 로고    scopus 로고
    • Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24
    • Tanaka F., Fujie T., Tahara K., Mori M., Takesako K., Sette A., Celis E., Akiyoshi T. Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24. Cancer Res. 1997, 57:4465-4468.
    • (1997) Cancer Res. , vol.57 , pp. 4465-4468
    • Tanaka, F.1    Fujie, T.2    Tahara, K.3    Mori, M.4    Takesako, K.5    Sette, A.6    Celis, E.7    Akiyoshi, T.8
  • 128
    • 33646094216 scopus 로고    scopus 로고
    • Adoptive T-cell transfer in cancer immunotherapy
    • Tey S.K., Bollard C.M., Heslop H.E. Adoptive T-cell transfer in cancer immunotherapy. Immunol. Cell Biol. 2006, 84:281-289.
    • (2006) Immunol. Cell Biol. , vol.84 , pp. 281-289
    • Tey, S.K.1    Bollard, C.M.2    Heslop, H.E.3
  • 130
    • 0036791206 scopus 로고    scopus 로고
    • Revelation of a cryptic major histocompatibility complex class II- restricted tumor epitope in a novel RNA-processing enzyme
    • Topalian S.L., Gonzales M.I., Ward Y., Wang X., Wang R.F. Revelation of a cryptic major histocompatibility complex class II- restricted tumor epitope in a novel RNA-processing enzyme. Cancer Res. 2002, 62:5505-5509.
    • (2002) Cancer Res. , vol.62 , pp. 5505-5509
    • Topalian, S.L.1    Gonzales, M.I.2    Ward, Y.3    Wang, X.4    Wang, R.F.5
  • 131
    • 33748126226 scopus 로고    scopus 로고
    • Recent approaches to intracellular delivery of drugs and DNA and organelle targeting
    • Torchilin V.P. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Annu. Rev. Biomed. Eng. 2006, 8:343-375.
    • (2006) Annu. Rev. Biomed. Eng. , vol.8 , pp. 343-375
    • Torchilin, V.P.1
  • 134
    • 0031568658 scopus 로고    scopus 로고
    • Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells
    • Tsai V., Southwood S., Sidney J., Sakaguchi K., Kawakami Y., Appella E., Sette A., Celis E. Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells. J. Immunol. 1997, 158:1796-1802.
    • (1997) J. Immunol. , vol.158 , pp. 1796-1802
    • Tsai, V.1    Southwood, S.2    Sidney, J.3    Sakaguchi, K.4    Kawakami, Y.5    Appella, E.6    Sette, A.7    Celis, E.8
  • 136
  • 138
    • 79953113656 scopus 로고    scopus 로고
    • Therapeutic vaccination against human papilloma virus induced malignancies
    • van der Burg S.H., Melief C.J. Therapeutic vaccination against human papilloma virus induced malignancies. Curr. Opin. Immunol. 2011, 23:252-257.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 252-257
    • van der Burg, S.H.1    Melief, C.J.2
  • 142
    • 0037115633 scopus 로고    scopus 로고
    • Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells
    • Voo K.S., Fu T., Heslop H.E., Brenner M.K., Rooney C.M., Wang R.F. Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells. Cancer Res. 2002, 62:7195-7199.
    • (2002) Cancer Res. , vol.62 , pp. 7195-7199
    • Voo, K.S.1    Fu, T.2    Heslop, H.E.3    Brenner, M.K.4    Rooney, C.M.5    Wang, R.F.6
  • 143
    • 13944284140 scopus 로고    scopus 로고
    • Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation
    • Voo K.S., Peng G., Guo Z., Fu T., Li Y., Frappier L., Wang R.F. Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation. Cancer Res. 2005, 65:1577-1586.
    • (2005) Cancer Res. , vol.65 , pp. 1577-1586
    • Voo, K.S.1    Peng, G.2    Guo, Z.3    Fu, T.4    Li, Y.5    Frappier, L.6    Wang, R.F.7
  • 144
    • 0034919646 scopus 로고    scopus 로고
    • The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity
    • Wang R.-F. The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity. Trends Immunol. 2001, 22:269-276.
    • (2001) Trends Immunol. , vol.22 , pp. 269-276
    • Wang, R.-F.1
  • 145
    • 0032880649 scopus 로고    scopus 로고
    • Human tumor antigens for cancer vaccine development
    • Wang R.F., Rosenberg S.A. Human tumor antigens for cancer vaccine development. Immunol. Rev. 1999, 170:85-100.
    • (1999) Immunol. Rev. , vol.170 , pp. 85-100
    • Wang, R.F.1    Rosenberg, S.A.2
  • 146
    • 0036168910 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells
    • Wang R.-F., Wang H.Y. Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells. Nat. Biotechnol. 2002, 20:149-156.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 149-156
    • Wang, R.-F.1    Wang, H.Y.2
  • 147
    • 0030472678 scopus 로고    scopus 로고
    • Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes
    • Wang R.-F., Appella E., Kawakami Y., Kang X., Rosenberg S.A. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. J. Exp. Med. 1996, 184:2207-2216.
    • (1996) J. Exp. Med. , vol.184 , pp. 2207-2216
    • Wang, R.-F.1    Appella, E.2    Kawakami, Y.3    Kang, X.4    Rosenberg, S.A.5
  • 148
    • 0029862690 scopus 로고    scopus 로고
    • Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen
    • Wang R.-F., Parkhurst M.R., Kawakami Y., Robbins P.F., Rosenberg S.A. Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. J. Exp. Med. 1996, 183:1131-1140.
    • (1996) J. Exp. Med. , vol.183 , pp. 1131-1140
    • Wang, R.-F.1    Parkhurst, M.R.2    Kawakami, Y.3    Robbins, P.F.4    Rosenberg, S.A.5
  • 149
    • 0031974725 scopus 로고    scopus 로고
    • Recognition of an antigenic peptide derived from TRP-2 by cytotoxic T lymphocytes in the context of HLA-A31 and -A33
    • Wang R.-F., Johnston S., Southwood S., Sette A., Rosenberg S.A. Recognition of an antigenic peptide derived from TRP-2 by cytotoxic T lymphocytes in the context of HLA-A31 and -A33. J. Immunol. 1998, 160:890-897.
    • (1998) J. Immunol. , vol.160 , pp. 890-897
    • Wang, R.-F.1    Johnston, S.2    Southwood, S.3    Sette, A.4    Rosenberg, S.A.5
  • 150
    • 0032186274 scopus 로고    scopus 로고
    • A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames
    • Wang R.-F., Johnston S.L., Zeng G., Schwartzentruber D.J., Rosenberg S.A. A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames. J. Immunol. 1998, 161:3596-3606.
    • (1998) J. Immunol. , vol.161 , pp. 3596-3606
    • Wang, R.-F.1    Johnston, S.L.2    Zeng, G.3    Schwartzentruber, D.J.4    Rosenberg, S.A.5
  • 151
    • 0033591429 scopus 로고    scopus 로고
    • Cloning genes encoding MHC class II-restricted antigens: Mutated CDC27 as a tumor antigen
    • Wang R.-F., Wang X., Atwood A.C., Topalian S.L., Rosenberg S.A. Cloning genes encoding MHC class II-restricted antigens: Mutated CDC27 as a tumor antigen. Science 1999, 284:1351-1354.
    • (1999) Science , vol.284 , pp. 1351-1354
    • Wang, R.-F.1    Wang, X.2    Atwood, A.C.3    Topalian, S.L.4    Rosenberg, S.A.5
  • 152
    • 0033577804 scopus 로고    scopus 로고
    • Identification of a novel MHC class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4+ T cells
    • Wang R.-F., Wang X., Rosenberg S.A. Identification of a novel MHC class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4+ T cells. J. Exp. Med. 1999, 189:1659-1667.
    • (1999) J. Exp. Med. , vol.189 , pp. 1659-1667
    • Wang, R.-F.1    Wang, X.2    Rosenberg, S.A.3
  • 153
    • 0036266363 scopus 로고    scopus 로고
    • Induction of CD4+ T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells
    • Wang H.Y., Fu T., Wang G., Gang Z., Donna M.P.-L., Yang J.C., Restifo N.P., Hwu P., Wang R.-F. Induction of CD4+ T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells. J. Clin. Invest. 2002, 109:1463-1470.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1463-1470
    • Wang, H.Y.1    Fu, T.2    Wang, G.3    Gang, Z.4    Donna, M.P.-L.5    Yang, J.C.6    Restifo, N.P.7    Hwu, P.8    Wang, R.-F.9
  • 154
    • 0037013827 scopus 로고    scopus 로고
    • Identification of a mutated fibronectin as a tumor antigen recognized by CD4+ T cells: Its role in extracellular matrix formation and tumor metastasis
    • Wang H.Y., Zhou J., Zhu K., Riker A.I., Marincola F.M., Wang R.-F. Identification of a mutated fibronectin as a tumor antigen recognized by CD4+ T cells: Its role in extracellular matrix formation and tumor metastasis. J. Exp. Med. 2002, 195:1397-1406.
    • (2002) J. Exp. Med. , vol.195 , pp. 1397-1406
    • Wang, H.Y.1    Zhou, J.2    Zhu, K.3    Riker, A.I.4    Marincola, F.M.5    Wang, R.-F.6
  • 155
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: Implication for immunotherapy
    • Wang H.Y., Lee D.A., Peng G., Guo Z., Li Y., Kiniwa Y., Shevach E.M., Wang R.-F. Tumor-specific human CD4+ regulatory T cells and their ligands: Implication for immunotherapy. Immunity 2004, 20:107-118.
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6    Shevach, E.M.7    Wang, R.-F.8
  • 156
    • 14044257258 scopus 로고    scopus 로고
    • Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells
    • Wang H.Y., Peng G., Guo Z., Shevach E.M., Wang R.-F. Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells. J. Immunol. 2005, 174:2661-2670.
    • (2005) J. Immunol. , vol.174 , pp. 2661-2670
    • Wang, H.Y.1    Peng, G.2    Guo, Z.3    Shevach, E.M.4    Wang, R.-F.5
  • 163
    • 0037058993 scopus 로고    scopus 로고
    • Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
    • Yee C., Thompson J.A., Byrd D., Riddell S.R., Roche P., Celis E., Greenberg P.D. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells. Proc. Natl. Acad. Sci. USA 2002, 99:16168-16173.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 16168-16173
    • Yee, C.1    Thompson, J.A.2    Byrd, D.3    Riddell, S.R.4    Roche, P.5    Celis, E.6    Greenberg, P.D.7
  • 167
  • 168
    • 0035957422 scopus 로고    scopus 로고
    • CD4+ T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA-DP4 allele: Association with NY-ESO-1 antibody production
    • Zeng G., Wang X., Robbins P.F., Rosenberg S.A., Wang R.-F. CD4+ T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA-DP4 allele: Association with NY-ESO-1 antibody production. Proc. Natl. Acad. Sci. USA 2001, 98:3964-3969.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3964-3969
    • Zeng, G.1    Wang, X.2    Robbins, P.F.3    Rosenberg, S.A.4    Wang, R.-F.5
  • 169
    • 79954571318 scopus 로고    scopus 로고
    • Cell surface signaling molecules in the control of immune responses: A tide model
    • Zhu Y., Yao S., Chen L. Cell surface signaling molecules in the control of immune responses: A tide model. Immunity 2011, 34:466-478.
    • (2011) Immunity , vol.34 , pp. 466-478
    • Zhu, Y.1    Yao, S.2    Chen, L.3
  • 170
    • 0032993152 scopus 로고    scopus 로고
    • A MAGE-6-encoded peptide is recognized by expanded lymphocytes infiltrating a spontaneously regressing human primary melanoma lesion
    • Zorn E., Hercend T. A MAGE-6-encoded peptide is recognized by expanded lymphocytes infiltrating a spontaneously regressing human primary melanoma lesion. Eur. J. Immunol. 1999, 29:602-607.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 602-607
    • Zorn, E.1    Hercend, T.2


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