A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression

Nature Medicine

Volumn 14, Issue 3, 2008, Pages 258-265

  Song, Xiao Tong ^a   Kabler, Kevin Evel ^a   Shen, Lei ^a   Rollins, Lisa ^a   Huang, Xue F ^a,b   Chen, Si Yi ^a,b  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN A20;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN FUNCTION; ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; HELPER CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; CELL DIFFERENTIATION; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYTOKINES; DENDRITIC CELLS; GENE SILENCING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTES, TUMOR-INFILTRATING; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; NEOPLASMS; RNA, SMALL INTERFERING; T-LYMPHOCYTES, REGULATORY;

EID: 40449128297     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1721     Document Type: Article

References (46)