Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

International Journal of Cancer

Volumn 80, Issue 2, 1999, Pages 219-230

  Marchand, Marie ^a,b,c   Van Baren, Nicolas ^a,b   Weynants, Patrick ^a,b,d   Brichard, Vincent ^a,b,c   Dréno, Brigitte ^e   Tessier, Marie Hélène ^e   Rankin, Elaine ^f   Parmiani, Giorgio ^g   Arienti, Flavio ^g   Humblet, Yves ^c   Bourlond, André ^c   Vanwijck, Romain ^c   Liénard, Danielle ^h   Beauduin, Marc ⁱ   Dietrich, Pierre Yves ^j   Russo, Vincenzo ^k   Kerger, Joseph ^l   Masucci, Giuseppe ^m   Jäger, Elke ⁿ   De Greve, Jacques ^o   Atzpodien, Jens ^p   Brasseur, Francis ^a,b   Coulie, Pierre G ^b   Van Der Bruggen, Pierre ^a,b   Boon, Thierry ^a,b   more..

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^d UNIVERSITY HOSPITAL OF MONT GODINNE   (Belgium)

^e HÔTEL DIEU   (France)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

^g Pediatric Oncology Unit   (Italy)

^h LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

ⁱ Hospital de Jolimont   (Belgium)

^j GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^k Immunotherapy and Gene Therapy Unit   (Italy)

^l JULES BORDET INSTITUTE   (Belgium)

^m KAROLINSKA INSTITUTE   (Sweden)

ⁿ KRANKENHAUS NORDWEST   (Germany)

^o UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^p HANNOVER MEDICAL SCHOOL   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE DERIVATIVE;

ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CASE REPORT; HLA SYSTEM; HUMAN; MELANOMA; METASTASIS; PRIORITY JOURNAL; TUMOR REGRESSION;

EID: 0033579934     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990118)80:2<219::AID-IJC10>3.0.CO;2-S     Document Type: Article

References (24)

1. AMERICAN JOINT COMMITTEE ON CANCER. Manual for staging of cancer. O.H. BEAHRS, D.E. HENSON, R.V.P HUTTER and B.J. KENNEDY (eds), pp. 143-148, J.B. Lippincott, Philadelphia (1992).
2. BALCH, C.M., HOUGHTON, A.N., MILTON, G.W., SOBER, A.J. and SOONG, S.-J. (eds.) Cutaneous melanoma. pp. 499, 516, 524, J.B. Lippincott, Philadelphia (1992).
3. BALDO, M., SCHIAVON, M., CICOGNA, P.A., BOCCATO, P. and MAZZOLENI, F., Spontaneous regression of subcutaneous metastasis of cutaneous melanoma. Plast. Reconstr. Surg., 90, 1073-1076 (1991).
4. BOON, T., CEROTTINI, J.-C., VAN DEN EYNDE, B., VAN DER BRUGGEN, P. and VAN PEL, A., Tumor antigens recognized by T lymphocytes, Ann. Rev. Immunol., 12, 337-365 (1994).
5. BRASSEUR, F. and 29 OTHERS, Expression of MAGE genes in primary and metastatic cutaneous melanoma. Int. J. Cancer, 63, 375-380 (1995).
6. CHAUX, P. VANTOMME, V., COULIE, P., BOON, T. and VAN DER BRUGGEN, P., Estimation of the frequencies of anti-MAGE-3 cytolytic T lymphocyte precursors in blood from individuals without cancer. Int. J. Cancer, 77, 538-542 (1998).
7. GAUGLER, B., VAN DEN EYNDE, B., VAN DER BRUGGEN, P., ROMERO, P., GAFORIO, J.J., DE PLAEN, E., LETHE, B., BRASSEUR, F. and BOON, T., Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. exp. Med., 179, 921-930 (1994).
8. HAHNE, M., RIMOLDI, D., SCHRÖTER, M., ROMERO, P., SCHREIER, M., FRENCH, L.E., SCHNEIDER, P., BORNAND, T., FONTANA, A., LIÉNARD, D., CEROTTINI, J.-C. and TSCHOPP, J., Melanoma cell expression of Fas (Apo-1/CD95) ligand: implications for tumor immune escape. Science, 274, 1363-1366 (1996).
9. INGE, T.H., HOOVER, S.K., SUSSKIND, B.M., BARRETT, S.K. and BEAR, H.D., Inhibition of tumor-specific cytotoxic T-lymphocyte responses by transforming growth factor beta 1. Cancer Res., 52, 1386-1392 (1992).
10. JAEGER, E., BERNHARD, H., ROMERO, P., RINGHOFFER, M., ARAND, M., KARBACH, J., ILSEMANN, C., HAGEDORN, M. and KNUTH, A., Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptides in vivo: implications for tumor vaccines with melanoma-associated antigens. Int. J. Cancer, 66, 162-169 (1996).
11. JAIN, R.K., KOENIG, G.C., DELLIAN, M., FUKUMURA, J.D., MUN, L.L. and MELDER, R.J., Leukocyte-endothelial adhesion and angiogenesis in tumors. Cancer Metastasis Rev., 15, 195-204 (1996).
12. MARCHAND, M. and 20 OTHERS, Tumor regression responses in melanoma patients treated with a peptide encoded by gene MAGE-3. Int. J. Cancer, 63, 883-885 (1995).
13. NESTLE, F.O., ALUAGIC, S., GILLIET, M., SUN, Y., GRABBE, S., DUMMER, R., BURG, G. and SCHADENDORF, D., Vaccination of melanoma patients with peptide-or tumor lysate-pulsed dendritic cells. Nature (Med.), 4, 328-332 (1998).
14. PIALI, L., FICHTEL, A., TERPE, H.-J., IMHOF, B.A. and GISLER, R.H., Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma. J. exp. Med., 181, 811-816 (1995).
15. ROSENBERG, S.A. and 15 OTHERS, Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature (Med.), 4, 321-327 (1998).
16. SPEISER, D.E., MIRANDA, R., ZAKARIAN, A., BACHMANN, M.F., MCKALL-FAIENZA, K., ODERMATT, B., HANAHAN, D., ZINKERNAGEL, R.M. and OHASHI, P.S., Self antigens expressed by solid tumors do not efficiently stimulate naive or activated T cells: implications for immunotherapy. J. exp. Med., 186, 645-653 (1997).
17. STORKUS, W.J., HOWELL, D.N., SALTER, R.D., DAWSON, J.R. and CRESSWELL, P., NK susceptibility varies inversely with target cell class I HLA antigen expression. J. Immunol., 138, 1657-1659 (1987).
18. TAKAHASHI, K., SHICHIJO, S., NOGUCHI, M., HIROHATA, M. and ITOH, K., Identification of MAGE-1 and MAGE-4 proteins in spermatogonia and primary spermatocytes of testis. Cancer Res., 55, 3478-3482 (1995).
19. TOMITA, Y., KIMURA, M., TANIKAWA, T., NISHIYAMA, T., MORISHITA, H., TAKEDA, M., FUJIWARA, M. and SATO, S., Immunohistochemical detection of intercellular adhesion molecule-1 (ICAM-1) and major histocompatibility complex class I antigens in seminoma. J. Urol., 149, 659-663 (1993).
20. TRAVERSARI, C., VAN DER BRUGGEN, P., LUESCHER, I.F., LURQUIN, C., CHOMEZ, P., VAN PEL, A., DE PLAEN, E., AMAR-COSTESEC, A. and BOON, T., A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-Al by cytolytic T lymphocytes directed against tumor antigen MZ2-E. J. Exp. Med., 176, 1453-1457 (1992).
21. UYTTENHOVE, C., GODFRAIND, C., LETHÉ, B., AMAR-COSTESEC, A., RENAULD, J.-C., GAJEWSKI, T.F., DUFFOUR, T., WARNIER, G., BOON, T. and VAN DEN EYNDE, B.J., The expression of mouse gene PIA in testis does not prevent safe induction of cytolytic T cells against a PIA-encoded tumor antigen. Int. J. Cancer, 70, 349-356 (1997).
22. VAN DER BRUGGEN, P., TRAVERSARI, C., CHOMEZ, P., LURQUIN, C., DE PLAEN, E., VAN DEN EYNDE, B., KNUTH, A. and BOON, T., A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science, 254, 1643-1647 (1991).
23. WARNIER, G., DUFFOUR, M.-T., UYTTENHOVE, C., PERRICAUDET, M., LURQUIN, C., HADDADA, H. and BOON, T., Induction of a cytolytic T cell response in mice with a recombinant adenovirus coding for tumor antigen P815A. Int. J. Cancer, 67, 303-310 (1996).
24. WEYNANTS, P., LETHÉ, B., BRASSEUR, F., MARCHAND, M. and BOON, T., Expression of MAGE genes by non-small-cell lung carcinomas. Int. J. Cancer, 56, 826-829 (1994).