Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry

Biochemistry

Volumn 42, Issue 31, 2003, Pages 9249-9256

  Sauve, Anthony A ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIFE SPAN REGULATION;

ACETYLATION; CATALYSIS; ENZYME INHIBITION; GENES; PROTEINS; YEAST;

BIOCHEMISTRY;

ACETIC ACID DERIVATIVE; ENZYME; HYDROXYL GROUP; LYSINE DERIVATIVE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; SILENT INFORMATION REGULATOR PROTEIN 2; UNCLASSIFIED DRUG;

ARCHAEOGLOBUS FULGIDUS; ARTICLE; CATALYSIS; COVALENT BOND; DEACETYLATION; GENE EXPRESSION; GENE SILENCING; LIFESPAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; STEREOCHEMISTRY;

ACETYLATION; ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; ARCHAEOGLOBUS FULGIDUS; BASE PAIRING; GENE EXPRESSION REGULATION, FUNGAL; HISTONE DEACETYLASES; LYSINE; MICE; MODELS, BIOLOGICAL; NAD; NIACINAMIDE; OXYGEN; PEPTIDE FRAGMENTS; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE; SIRTUINS; SPECIES SPECIFICITY;

ARCHAEOGLOBUS FULGIDUS; BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 0041571570     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034959l     Document Type: Article

References (34)

1. Landry, J., Sutton, A., Tafrov, S. T., Heller, R. C., Stebbins, J., Pillus, L., and Sternglanz, R. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 5807-5811.
2. Imai, S., Armstrong, C. M., Kaeberlain, M., and Guarente, L. (2000) Nature 403, 795-800.
3. Smith, J. S., Brachmann, C. B., Celic, I., Kenna, M. A., Muhammad, S., Starai, V. J., Avalos, J. L., Escalente-Semerena, J. C., Grubmeyer, C., Wolberger, C., and Boeke, J. D. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 6658-6663.
4. Rine, J., and Herskowitz, I. (1987) Genetics 116, 9-22.
5. Rusche, L. N., Kirchmaier, A. L., and Rine, J. (2003) Annu. Rev. Biochem. 72, 481-516.
6. Anderson, R. M., Bitterman, K. J., Wood, J. G., Medvedik, O., and Sinclair, D. A. (2003) Nature 423, 181-185.
7. Braunstein, M., Rose, A. B., Holmes, S. C., Allis, C. D., and Broach, J. R. (1993) Genes Dev. 7, 592-604.
8. Brachmann, C. B., Sherman, J. M., Devine, S. E., Comeron, E. E., Pillus, L., and Boeke, J. D. (1995) Genes Dev. 9, 2888-2902.
9. Lin, S. J., Deffossez, P. A., and Guarente, L. (2000) Science 289, 2126-2128.
10. Tissenbaum, H. A., and Guarente, L. (2000) Nature 410, 227-230.
11. Astrom, S. U., Cline, T. W., and Rine, J. (2003) Genetics 163, 931-937.
12. Lin, S. J., and Guarente, L. (2002) Nature 418, 344-348.
13. Campisi, J. (2000) Science 289, 2062-2063.
14. Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M., and Sinclair, D. A. (2002) J. Biol. Chem. 277, 45099-45107.
15. Anderson, R. M., Bitterman, K. J., Wood, J. G., Medvedik, O., Cohen, H., Lin, S. S., Manchester, J. K., Gordon, J. I., and Sinclair, D. A. (2002) J. Biol. Chem. 277, 18881-18890.
16. Sinclair, D. A. (2002) Mech. Ageing Dev. 123, 857-867.
17. Gasch, A. P., Spellman, P. T., Kao, C. M., Carmel-Harel, O., Eisen, M. B., Storz, G., Botstein, D., and Brown, P. O. (2000) Mol. Biol. Cell 11, 4241-4257.
18. Landry, J., Slama, J. T., and Sternglanz, R. (2000) Biochem. Biophys. Res. Commun. 278, 685-690.
19. Min, J., Landry, J., Sternglanz, R., and Xu, R. M. (2001) Cell 105, 269-279.
20. Sauve, A. A., Celic, I., Avalos, J., Boeke, J. D., and Schramm, V. L. (2001) Biochemistry 40, 15456-15463.
21. Jackson, M. D., and Denu, J. M. (2002) J. Biol. Chem. 277, 18535-18544.
22. Tanner, K. G., Landry, J., Sternglanz, R., and Denu, J. M. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 14178-14182.
23. Tanny, J. C., and Moazed, D. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 415-420.
24. Sauve, A. A., Munshi, C., Lee, H. C., and Schramm, V. L. (1998) Biochemistry 37, 13239-13249.
25. Vaziri, H., Dessain, S. K., Eaton, E. N., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L., and Weinberg, R. A. (2001) Cell 107, 149-159.
26. Luo, J., Nikolaev, A. Y., Imai, S., Chen, D., Su, F., Shiloh, A., Guarente, L., and Gu, W. (2001) Cell 107, 137-148.
27. North, B. J., Marshall, B. L., Borra, M. T., Denu, J. M., and Verdin, E. (2003) Mol. Cell 2, 437-444.
28. Starai, V. J., Celic, I., Cole, R. N., Boeke, J. D., and Escalante-Semerena, J. C. (2003) Science 298, 2390-2392.
29. Bell, S. D., Botting, C. H., Wardleworth, B. N., Jackson, S. P., and White, M. F. (2002) Science 296, 148-151.
30. Berti, P. J., and Schramm, V. L. (1997) J. Am. Chem. Soc. 119, 12069-12078.
31. Scheuring, J., and Schramm, V. L. (1997) Biochemistry 36, 4526-4534.
32. Knapp, S., Vocadlo, D., Gao, Z., Kirk, B., Lou, J., and Withers, S. G. (1996) J. Am. Chem. Soc. 118, 6804-6805.
33. Zechel, D. L., and Withers, S. G. (2000) Acc. Chem. Res. 33, 11-18.
34. Sauve, A. A., Deng, H., Angeletti, R. H., and Schramm, V. L. (2000) J. Am. Chem. Soc. 122, 7855-7859.