Specific noncovalent interactions at protein-ligand interface: Implications for rational drug design

Current Medicinal Chemistry

Volumn 19, Issue 2, 2012, Pages 226-238

  Zhou, P ^a,b   Huang, J ^a,b   Tian, F ^a,b  

^a UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b SOUTHWEST JIAOTONG UNIVERSITY   (China)

Author keywords

Crystal structure survey; Noncovalent interaction; Protein ligand recognition; Quantum mechanical calculation; Rational drug design

Indexed keywords

AMMONIA; BROMIDE; CARBOXYL GROUP; CHLORIDE; HALOGEN; HYDROGEN; IODINE; LIGAND; ORGANOFLUORINE DERIVATIVE; PHOSPHATE; PROTEIN; SODIUM CHLORIDE; SULFATE; SULFUR;

ARTICLE; BINDING AFFINITY; BIOLOGICAL FUNCTIONS; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DRUG DESIGN; ELECTRON; ENTHALPY; HYDROGEN BOND; LIGAND BINDING; PROTEIN BINDING; PROTEIN LIPID INTERACTION; STATIC ELECTRICITY;

EID: 84863250545     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712803414150     Document Type: Article

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