Evaluating the potential for halogen bonding in the oxyanion hole of ketosteroid isomerase using unnatural amino acid mutagenesis

ACS Chemical Biology

Volumn 4, Issue 4, 2009, Pages 269-273

  Kraut, Daniel A ^a,c   Churchill, Michael J ^b   Dawson, Phillip E ^b   Herschlag, Daniel ^a  

^a STANFORD UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BROMINE; CHLORINE; HALOGEN; IODINE; NITROGEN; OXYGEN; PHENYLALANINE DERIVATIVE; STEROID DELTA ISOMERASE; TYROSINE;

ARTICLE; CONFORMATION; ELECTRICITY; ENERGY TRANSFER; GEOMETRY; HYDROGEN BOND; MACROMOLECULE; MOLECULAR INTERACTION; MUTAGENESIS; MUTATION; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIONS; BINDING SITES; HYDROCARBONS, HALOGENATED; HYDROGEN; MUTAGENESIS, SITE-DIRECTED; OXYGEN; STEROID ISOMERASES; TYROSINE;

EID: 65649131517     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb900016q     Document Type: Article

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