The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis

Journal of Biological Chemistry

Volumn 287, Issue 7, 2012, Pages 5091-5101

  Min, Jaewon ^a   Choi, Eun Shik ^a   Hwang, Kwangwoo ^a   Kim, Jimi ^a   Sampath, Srihari ^b,c   Venkitaraman, Ashok R ^b   Lee, Hyunsook ^a  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFTER-TREATMENT; BREAST CANCER; CHROMOSOMAL REARRANGEMENT; CHROMOSOME ABERRATION; DNA DAMAGE RESPONSE; DNA REPAIR; GENETIC INTEGRITY; LAGGING STRAND; MOUSE-FIBROBLASTS; S-PHASE; SISTER CHROMATID EXCHANGE; STRUCTURAL INSTABILITY; SUSCEPTIBILITY GENES; TELOMERE MAINTENANCE; TELOMERES;

CELL CULTURE; GENES; MAINTENANCE; PHYSIOLOGY;

DISEASES;

CRE RECOMBINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CELL DIVISION; CELL PROLIFERATION; CHROMATID EXCHANGE; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; FIBROBLAST; GENETIC RECOMBINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TELOMERE HOMEOSTASIS; TUMOR SUPPRESSOR GENE;

ANIMALS; BRCA2 PROTEIN; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA DAMAGE; FIBROBLASTS; HOMEOSTASIS; HUMANS; MICE; MICE, KNOCKOUT; S PHASE; SISTER CHROMATID EXCHANGE; TELOMERE;

EID: 84863142576     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.278994     Document Type: Article

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