-
1
-
-
0029051439
-
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A. 1995; 92:5510-5514.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
2
-
-
0035917313
-
2 sensing
-
2 sensing. Science. 2001; 292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
3
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science. 2001; 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
4
-
-
43649093915
-
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
-
Kaelin WG, Jr, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell. 2008; 30:393-402.
-
(2008)
Mol Cell
, vol.30
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
5
-
-
71049171143
-
Identification of chemical compounds that induce HIF-1alpha activity
-
Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin CP. Identification of chemical compounds that induce HIF-1alpha activity. Toxicol Sci. 2009; 112:153-63.
-
(2009)
Toxicol Sci
, vol.112
, pp. 153-163
-
-
Xia, M.1
Huang, R.2
Sun, Y.3
Semenza, G.L.4
Aldred, S.F.5
Witt, K.L.6
Inglese, J.7
Tice, R.R.8
Austin, C.P.9
-
6
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G L. Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 2003; 3:721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
7
-
-
77950922592
-
Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy
-
McCarty MF, Barroso-Aranda J, Contreras F. Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy. Med Hypotheses. 2010; 74:789-797.
-
(2010)
Med Hypotheses
, vol.74
, pp. 789-797
-
-
McCarty, M.F.1
Barroso-Aranda, J.2
Contreras, F.3
-
8
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene. 2010; 29:625-634.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
9
-
-
78650797956
-
Zinc downregulates HIF-1a and inhibits its activity in tumor cells in vitro and in vivo
-
Nardinocchi L, Pantisano V, Puca R, Porru M, Aiello A, Grasselli A, Leonetti C, Safran M, Rechavi G, Givol D, Farsetti A, D'Orazi G. Zinc downregulates HIF-1a and inhibits its activity in tumor cells in vitro and in vivo. PLoS ONE. 2010; 5:1-12.
-
(2010)
PLoS ONE
, vol.5
, pp. 1-12
-
-
Nardinocchi, L.1
Pantisano, V.2
Puca, R.3
Porru, M.4
Aiello, A.5
Grasselli, A.6
Leonetti, C.7
Safran, M.8
Rechavi, G.9
Givol, D.10
Farsetti, A.11
D'Orazi, G.12
-
10
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell. 2009; 15:232-239.
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
11
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, Inoue M, Bergers G, Hanahan D, Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell. 2009; 15:220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Pàez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Viñals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
12
-
-
49849084552
-
Requirement of hypoxia-inducible factor-1alpha downregulation in mediating the antitumor activity of the antiepidermal growth factor receptor monoclonal antibody cetuximab
-
Li X, Lu Y, Liang K, Pan T, Mendelsohn J, Fan Z. Requirement of hypoxia-inducible factor-1alpha downregulation in mediating the antitumor activity of the antiepidermal growth factor receptor monoclonal antibody cetuximab. Mol Cancer Ther. 2008; 7:1207-1217.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1207-1217
-
-
Li, X.1
Lu, Y.2
Liang, K.3
Pan, T.4
Mendelsohn, J.5
Fan, Z.6
-
13
-
-
0035696301
-
Functions of zinc in signaling, proliferation and differentiation of mammalian cells
-
Beyersmann D, Haase H. Functions of zinc in signaling, proliferation and differentiation of mammalian cells. Biometals. 2001; 14:331-341.
-
(2001)
Biometals
, vol.14
, pp. 331-341
-
-
Beyersmann, D.1
Haase, H.2
-
14
-
-
59149085523
-
Mechanisms of mammalian zinc-regulated gene expression
-
Jackson KA, Valentine RA, Coneyworth LJ, Mathers JC, Ford D. Mechanisms of mammalian zinc-regulated gene expression. Biochem Soc Trans. 2008; 36:1262-1266.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 1262-1266
-
-
Jackson, K.A.1
Valentine, R.A.2
Coneyworth, L.J.3
Mathers, J.C.4
Ford, D.5
-
15
-
-
79953710016
-
Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis
-
Fong LY, Jiang Y, Rawahneh ML, Smalley KJ, Croce CM, Farber JL, Huebner K. Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis. Carcinogenesis. 2011; 32:554-560.
-
(2011)
Carcinogenesis
, vol.32
, pp. 554-560
-
-
Fong, L.Y.1
Jiang, Y.2
Rawahneh, M.L.3
Smalley, K.J.4
Croce, C.M.5
Farber, J.L.6
Huebner, K.7
-
16
-
-
7944222171
-
Zinc deficiency DNA damage and cancer risk
-
Ho E. Zinc deficiency, DNA damage and cancer risk. J Nutr Biochem. 2004; 15:572-578.
-
(2004)
J Nutr Biochem
, vol.15
, pp. 572-578
-
-
Ho, E.1
-
17
-
-
69949108875
-
Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha
-
Nardinocchi L, Puca R, Sacchi A, Rechavi G, Givol D, D'Orazi G. Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha. PLoS ONE. 2009; 4:6819.
-
(2009)
PLoS ONE
, vol.4
, pp. 6819
-
-
Nardinocchi, L.1
Puca, R.2
Sacchi, A.3
Rechavi, G.4
Givol, D.5
D'Orazi, G.6
-
18
-
-
45549086243
-
Reversible dysfunction of wild-type p53 following homeodomaininteracting protein kinase-2 knockdown
-
Puca R, Nardinocchi L, Gal H, Rechavi G, Amariglio N, Domany E, Notterman DA, Scarsella M, Leonetti C, Sacchi A, Blandino G, Givol D, D'Orazi G. Reversible dysfunction of wild-type p53 following homeodomaininteracting protein kinase-2 knockdown. Cancer Res. 2008; 68:3707-3714.
-
(2008)
Cancer Res
, vol.68
, pp. 3707-3714
-
-
Puca, R.1
Nardinocchi, L.2
Gal, H.3
Rechavi, G.4
Amariglio, N.5
Domany, E.6
Notterman, D.A.7
Scarsella, M.8
Leonetti, C.9
Sacchi, A.10
Blandino, G.11
Givol, D.12
D'Orazi, G.13
-
19
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genomewide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genomewide expression profiles. Proc Natl Acad Sci U S A. 2005; 102:15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
20
-
-
33644551073
-
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
-
Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med. 2006; 3:e47.
-
(2006)
PLoS Med
, vol.3
-
-
Chi, J.T.1
Wang, Z.2
Nuyten, D.S.3
Rodriguez, E.H.4
Schaner, M.E.5
Salim, A.6
Wang, Y.7
Kristensen, G.B.8
Helland, A.9
Børresen-Dale, A.L.10
Giaccia, A.11
Longaker, M.T.12
Hastie, T.13
Yang, G.P.14
van de Vijver, M.J.15
Brown, P.O.16
-
21
-
-
33744954065
-
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways
-
Elvidge GP, Glenny L, Appelhoff RJ, Ratcliffe PJ, Ragoussis J, Gleadle JM. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem. 2006; 281:15215-15226.
-
(2006)
J Biol Chem
, vol.281
, pp. 15215-15226
-
-
Elvidge, G.P.1
Glenny, L.2
Appelhoff, R.J.3
Ratcliffe, P.J.4
Ragoussis, J.5
Gleadle, J.M.6
-
22
-
-
0036359548
-
Hypoxia--a key regulatory factor in tumour growth
-
Harris AL. Hypoxia--a key regulatory factor in tumour growth. Nat Rev Cancer. 2002; 2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
23
-
-
0037395395
-
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways
-
Jiang Y, Zhang W, Kondo K, Klco JM, St Martin TB, Dufault MR, Madden SL, Kaelin WG Jr, Nacht M. Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways. Mol Cancer Res. 2003; 1:453-462.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 453-462
-
-
Jiang, Y.1
Zhang, W.2
Kondo, K.3
Klco, J.M.4
St Martin, T.B.5
Dufault, M.R.6
Madden, S.L.7
Kaelin Jr., W.G.8
Nacht, M.9
-
24
-
-
0141890293
-
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia
-
Leonard MO, Cottell DC, Godson C, Brady HR, Taylor CT. The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem. 2003; 278:40296-40304.
-
(2003)
J Biol Chem
, vol.278
, pp. 40296-40304
-
-
Leonard, M.O.1
Cottell, D.C.2
Godson, C.3
Brady, H.R.4
Taylor, C.T.5
-
25
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
Manalo DJ, Rowan A, Lavoie T, Natarajan L, Kelly BD, Ye SQ, Garcia JG, Semenza GL. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood. 2005; 105:659-669.
-
(2005)
Blood
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
26
-
-
33646765735
-
Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes
-
Mense SM, Sengupta A, Zhou M, Lan C, Bentsman G, Volsky DJ, Zhang L. Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes. Physiol Genomics. 2006; 25:435-449
-
(2006)
Physiol Genomics
, vol.25
, pp. 435-449
-
-
Mense, S.M.1
Sengupta, A.2
Zhou, M.3
Lan, C.4
Bentsman, G.5
Volsky, D.J.6
Zhang, L.7
-
27
-
-
24744438663
-
Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells
-
Mizukami Y, Jo WS, Duerr EM, Gala M, Li J, Zhang X, Zimmer MA, Iliopoulos O, Zukerberg LR, Kohgo Y, Lynch MP, Rueda BR, Chung DC. Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells. Nat Med. 2005; 11:992-997.
-
(2005)
Nat Med
, vol.11
, pp. 992-997
-
-
Mizukami, Y.1
Jo, W.S.2
Duerr, E.M.3
Gala, M.4
Li, J.5
Zhang, X.6
Zimmer, M.A.7
Iliopoulos, O.8
Zukerberg, L.R.9
Kohgo, Y.10
Lynch, M.P.11
Rueda, B.R.12
Chung, D.C.13
-
28
-
-
26944465042
-
Array-based comparative gene expression analysis of tumor cells with increased apoptosis resistance after hypoxic selection
-
Weinmann M, Belka C, Güner D, Goecke B, Müller I, Bamberg M, Jendrossek V. Array-based comparative gene expression analysis of tumor cells with increased apoptosis resistance after hypoxic selection. Oncogene. 2005; 24:5914-5922.
-
(2005)
Oncogene
, vol.24
, pp. 5914-5922
-
-
Weinmann, M.1
Belka, C.2
Güner, D.3
Goecke, B.4
Müller, I.5
Bamberg, M.6
Jendrossek, V.7
-
29
-
-
34248172298
-
Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers
-
Winter SC, Buffa FM, Silva P, Miller C, Valentine HR, Turley H, Shah KA, Cox GJ, Corbridge RJ, Homer JJ, Musgrove B, Slevin N, Sloan P, Price P, West CM, Harris AL. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res. 2007; 67:3441-3449.
-
(2007)
Cancer Res
, vol.67
, pp. 3441-3449
-
-
Winter, S.C.1
Buffa, F.M.2
Silva, P.3
Miller, C.4
Valentine, H.R.5
Turley, H.6
Shah, K.A.7
Cox, G.J.8
Corbridge, R.J.9
Homer, J.J.10
Musgrove, B.11
Slevin, N.12
Sloan, P.13
Price, P.14
West, C.M.15
Harris, A.L.16
-
30
-
-
25144472027
-
Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells
-
Vengellur A, Phillips JM, Hogenesch JB, LaPres JJ. Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells. Physiol Genomics. 2005; 22:308-318.
-
(2005)
Physiol Genomics
, vol.22
, pp. 308-318
-
-
Vengellur, A.1
Phillips, J.M.2
Hogenesch, J.B.3
LaPres, J.J.4
-
31
-
-
0345170089
-
Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts
-
Vengellur A, Woods BG, Ryan HE, Johnson RS, LaPres JJ. Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts. Gene Expr. 2003; 11:181-197.
-
(2003)
Gene Expr
, vol.11
, pp. 181-197
-
-
Vengellur, A.1
Woods, B.G.2
Ryan, H.E.3
Johnson, R.S.4
LaPres, J.J.5
-
32
-
-
66349121718
-
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
-
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouysségur J, Mazure NM. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol. 2009; 29:2570-2581.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouysségur, J.6
Mazure, N.M.7
-
33
-
-
62749124795
-
Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9 A one transcription factor (HIF-1) show?
-
Kaluz S, Kaluzova M, Liao SY, Lerman M, Stanbridge EJ. Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show? Biochim Biophys Acta. 2009; 1795:162-172.
-
(2009)
Biochim Biophys Acta
, vol.1795
, pp. 162-172
-
-
Kaluz, S.1
Kaluzova, M.2
Liao, S.Y.3
Lerman, M.4
Stanbridge, E.J.5
-
34
-
-
0029820166
-
Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database
-
Allikmets R, Gerrard B, Hutchinson A, Dean M. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum Mol Genet. 1996; 5:1649-1655.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1649-1655
-
-
Allikmets, R.1
Gerrard, B.2
Hutchinson, A.3
Dean, M.4
-
35
-
-
69049111041
-
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
-
Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ. An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. Nucleic Acids Res. 2009; 37:4587-4602.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4587-4602
-
-
Benita, Y.1
Kikuchi, H.2
Smith, A.D.3
Zhang, M.Q.4
Chung, D.C.5
Xavier, R.J.6
-
36
-
-
41949130508
-
Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1
-
Choi DW, Seo YM, Kim EA, Sung KS, Ahn JW, Park SJ, Lee SR, Choi CY. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1. J Biol Chem. 2008; 283:4682-4689.
-
(2008)
J Biol Chem
, vol.283
, pp. 4682-4689
-
-
Choi, D.W.1
Seo, Y.M.2
Kim, E.A.3
Sung, K.S.4
Ahn, J.W.5
Park, S.J.6
Lee, S.R.7
Choi, C.Y.8
-
37
-
-
70449719002
-
HIPK2 modulates p53 activity towards proapoptotic transcription
-
Puca R, Nardinocchi L, Sacchi A, Rechavi G, Givol D, D'Orazi G. HIPK2 modulates p53 activity towards proapoptotic transcription. Mol Cancer. 2009; 14:8:85.
-
(2009)
Mol Cancer
, vol.14
, Issue.8
, pp. 85
-
-
Puca, R.1
Nardinocchi, L.2
Sacchi, A.3
Rechavi, G.4
Givol, D.5
D'Orazi, G.6
-
38
-
-
58149354210
-
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response
-
Calzado MA, de la Vega L, Moller A, Bowtell DD, Schmitz ML. An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response. Nature Cell Biol. 2009; 11:85-91.
-
(2009)
Nature Cell Biol
, vol.11
, pp. 85-91
-
-
Calzado, M.A.1
de la Vega, L.2
Moller, A.3
Bowtell, D.D.4
Schmitz, M.L.5
-
39
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nature Genet. 2006; 38:904-909.
-
(2006)
Nature Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
40
-
-
54549089738
-
Hypoxia signalling through mTOR and the unfolded protein response in cancer
-
Wouters BG, Koritzinsky M. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer. 2008; 8:851-864.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 851-864
-
-
Wouters, B.G.1
Koritzinsky, M.2
-
41
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004; 11:891-899.
-
(2004)
Nat Rev Cancer
, vol.11
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
42
-
-
33749478922
-
Cancer's molecular sweet tooth and the Warburg effect
-
Kim JW, Dang CV. Cancer's molecular sweet tooth and the Warburg effect. Cancer Res. 2006; 66:8927-8930.
-
(2006)
Cancer Res
, vol.66
, pp. 8927-8930
-
-
Kim, J.W.1
Dang, C.V.2
-
43
-
-
34147172349
-
HIF-1-regulated glucose metabolism A key to apoptosis resistance?
-
Fulds S, Debatin K-M. HIF-1-regulated glucose metabolism. A key to apoptosis resistance? Cell Cycle. 2007; 6:790-792.
-
(2007)
Cell Cycle
, vol.6
, pp. 790-792
-
-
Fulds, S.1
Debatin, K.-M.2
-
44
-
-
77953184918
-
HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase
-
Sendoel A, Kohler I, Fellmann C, Lowe SW, Hengsrtner MO. HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase. Nature. 2010; 465:577-583.
-
(2010)
Nature
, vol.465
, pp. 577-583
-
-
Sendoel, A.1
Kohler, I.2
Fellmann, C.3
Lowe, S.W.4
Hengsrtner, M.O.5
-
45
-
-
79958289721
-
HIF-1a antagonizes p53-mediated apoptosis by triggering HIPK2 degradation
-
Nardinocchi L, Puca R, D'Orazi G. HIF-1a antagonizes p53-mediated apoptosis by triggering HIPK2 degradation. Aging (Albany NY). 2011; 3:33-43.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 33-43
-
-
Nardinocchi, L.1
Puca, R.2
D'Orazi, G.3
-
47
-
-
77957148038
-
Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/ p53 apoptotic signaling in cancer cells
-
Nardinocchi L, Puca R, Givol D, D'Orazi G. Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/ p53 apoptotic signaling in cancer cells. FEBS Lett. 2010; 584:4253-4258.
-
(2010)
FEBS Lett
, vol.584
, pp. 4253-4258
-
-
Nardinocchi, L.1
Puca, R.2
Givol, D.3
D'Orazi, G.4
-
48
-
-
85039674862
-
-
Affymetrix. Guide to probe logarithmic intensity error (PLIER) estimation. available at
-
Affymetrix. Guide to probe logarithmic intensity error (PLIER) estimation. available at http://www.affymetrix.com/support/technical/technotes/plier_technote.pdf. 2005.
-
(2005)
-
-
-
50
-
-
77954871394
-
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
-
Zeisel A, Amir A, Kostler WJ, Domany E. Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes. BMC Bioinformatics. 2010; 11:400-407.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 400-407
-
-
Zeisel, A.1
Amir, A.2
Kostler, W.J.3
Domany, E.4
-
51
-
-
19544387813
-
Sorting points into neighborhoods (SPIN): data analysis and visualization by ordering distance matrices
-
Tsafrir D, Tsafrir I, Ein-Dor L, Zuk O, Notterman DA, Domany E. Sorting points into neighborhoods (SPIN): data analysis and visualization by ordering distance matrices. Bioinformatics. 2005; 21:2301-2308.
-
(2005)
Bioinformatics
, vol.21
, pp. 2301-2308
-
-
Tsafrir, D.1
Tsafrir, I.2
Ein-Dor, L.3
Zuk, O.4
Notterman, D.A.5
Domany, E.6
|