Identification of chemical compounds that induce HIF-1α activity

Toxicological Sciences

Volumn 112, Issue 1, 2009, Pages 153-163

  Xia, Menghang ^a   Huang, Ruili ^a   Sun, Yi ^b   Semenza, Gregg L ^c   Aldred, Shelley Force ^d   Witt, Kristine L ^e   Inglese, James ^a   Tice, Raymond R ^e   Austin, Christopher P ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d SwitchGear Genomics   (United States)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

7,12 dimethylbenz(a)anthracence; 7 diethylamino 4 methylcoumarin; Cobalt sulfate heptahydrate; HIF 1 ; Inducers; Iodochlorohydroxyquinoline; NTP 1408 compound library; o phenanthroline; qHTS

Indexed keywords

7 DIETHYLAMINO 4 METHYLCOUMARIN; 7,12 DIMETHYLBENZ ANTHRACENE; ANTHRACENE DERIVATIVE; BETA LACTAMASE; CLIOQUINOL; COBALT SULFATE; COUMARIN DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHENANTHROLINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; CELL ASSAY; CELL HYPOXIA; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

BETA-LACTAMASES; CELL LINE; CLIOQUINOL; COBALT; DRUG EVALUATION, PRECLINICAL; GENES, REPORTER; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PHENANTHROLINES; SIGNAL TRANSDUCTION;

EID: 71049171143     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp123     Document Type: Article

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