Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes

Journal of Lipid Research

Volumn 53, Issue 7, 2012, Pages 1359-1368

  Engelking, Luke J ^a   McFarlane, Matthew R ^a   Li, Christina K ^a   Liang, Guosheng ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cholesterol absorption; Cholesterol biosynthesis; HMG CoA reductase; LDL metabolism; Lipoproteins receptors; Nuclear receptors

Indexed keywords

CHOLESTEROL; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; KEXIN; KEXIN TYPE 9; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; STEROL REGULATORY ELEMENT BINDING PROTEIN; SUBTILISIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CHOLESTEROL HOMEOSTASIS; CHOLESTEROL SYNTHESIS; CONCENTRATION (PARAMETERS); GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HOMEOSTASIS; INDUCIBLE DEGRADER OF LOW DENSITY LIPOPROTEIN RECEPTOR GENE; INTESTINE; INTESTINE CELL; LIPID ABSORPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; RECEPTOR UPREGULATION; STEROL SYNTHESIS;

ANIMALS; AZETIDINES; CHOLESTEROL; ENTEROCYTES; HOMEOSTASIS; INTESTINAL ABSORPTION; INTESTINES; MICE; MICE, INBRED C57BL; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UP-REGULATION;

EID: 84862337034     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M027599     Document Type: Article

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