Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 295, Issue 4, 2008, Pages

  Valasek, Mark A ^a   Repa, Joyce J ^a   Quan, Gang ^a   Dietschy, John M ^a   Turley, Stephen D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cholesterol absorption; Cholesterol gallstone disease; Enterocyte; Gallbladder bile; Liver

Indexed keywords

EZETIMIBE; MESSENGER RNA; NIEMANN PICK DISEASE TYPE C1 LIKE L1 PROTEIN; PROTEIN DERIVATIVE; SAFFLOWER OIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG DOSE ESCALATION; FEMALE; GALLBLADDER; GASTROINTESTINAL TRACT; GOLDEN SYRIAN HAMSTER; HAMSTER; HOMEOSTASIS; INTESTINE ABSORPTION; INTESTINE CELL; LIPID COMPOSITION; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SINGLE DRUG DOSE; SMALL INTESTINE; STEROL EXCRETION; STEROL SYNTHESIS;

ANIMALS; AZETIDINES; BILE; CHOLESTEROL; CHOLESTEROL, DIETARY; CRICETINAE; DIETARY FATS; FECES; FEMALE; INTESTINAL ABSORPTION; INTESTINE, SMALL; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; MESOCRICETUS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 57349162139     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90372.2008     Document Type: Article

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