Recent trends in oral transmucosal drug delivery systems: An emphasis on the soft palatal route

Expert Opinion on Drug Delivery

Volumn 9, Issue 6, 2012, Pages 629-647

  Satheesh Madhav, Nookala Venkala ^a   Semwal, Ravindra ^a   Semwal, Deepak Kumar ^b   Semwal, Ruchi B ^b  

^a DIT UNIVERSITY   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Bio polymer; Buccal route; Drug delivery; Soft palates; Sublingual route; Transmucosa

Indexed keywords

ACICLOVIR; ACT FLUORIDE RINSE; AMANTADINE; ANDROGEN; ASENAPINE; BEMA; BENZYDAMINE; BIOPOLYMER; BUPRENORPHINE; BUPRENORPHINE HCL; CALCITONIN; CARVEDILOL; FENTANYL; FENTANYL CITRATE; FLUORIDE; GEL KAM; GELCLAIR; GLYCERYL TRINITRATE; GLYCOPROTEIN; GLYCYRRHETINIC ACID; HYALURONIC ACID; INSULIN; LAURIAD; LORAMYC; MICONAZOLE; MICROSPHERE; MUCIN; NANOCARRIER; NICOTINE; OXYMETHOLONE; PARATHYROID HORMONE[1-34]; PENETRATION ENHANCING AGENT; POLYMER; POVIDONE; PROGESTERONE; PROPRANOLOL; RAPAMYCIN; TIZANIDINE; UNCLASSIFIED DRUG; VALDECOXIB;

ANGINA PECTORIS; AQUEOUS SOLUTION; BACTERIUM ADHERENCE; BIOPLATE; BUCCAL DRUG ADMINISTRATION; CHEEK MUCOSA; CHEWING GUM; DENTAL CARIES; DRUG ABSORPTION; DRUG ADMINISTRATION; DRUG BIOAVAILABILITY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG MECHANISM; DRUG METABOLISM; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; FLEXIPLATE; GEL; GLYCOSYLATION; HERPES LABIALIS; HUMAN; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; LAMINA PROPRIA; LIVER DISEASE; LOZENGE; MEMBRANE PERMEABILITY; MOUTH DISEASE; MOUTH IRRITATION; MOUTH PAIN; MUCOSAL ADMINISTRATION; NONHUMAN; OROPHARYNX CANDIDIASIS; PAIN; PATENT; PATIENT COMPLIANCE; PHYSIOLOGY; PROTEIN STRUCTURE; REVIEW; SOFT PALATAL DRUG ADMINISTRATION; SUBLINGUAL DRUG ADMINISTRATION; TABLET; TABLET DISINTEGRATION; TRANSDERMAL PATCH; TREND STUDY; VIRUS INFECTION;

ADMINISTRATION, MUCOSAL; ANIMALS; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; HUMANS; MOUTH MUCOSA; PALATE, SOFT; PHARMACEUTICAL PREPARATIONS;

EID: 84862078161     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2012.679260     Document Type: Review

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142. Park CR, Munday DL. Evaluation of selected polysaccharide excipients in buccoadhesive tablets for sustained release of nicotine. Drug Dev Ind Pharm 2004;30:609-17 (Pubitemid 38924631)
143. Perioli L, Ambrogi V, Rubini D, et al. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease. J Control Release 2004;95:521-33 (Pubitemid 38340502)
144. Nafee NA, Boraie MA, Ismail FA, et al. Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride. Acta Pharm 2003;53:199-212 (Pubitemid 37314581)
145. Jug M, Becirevic-Lacan M. Influence of hydroxypropyl-beta-cyclodextrin complexation on piroxicam release from buccoadhesive tablets. Eur J Pharm Sci 2004;21:251-60 (Pubitemid 38156162)
146. Nafee NA, Ismail FA, Boraie NA, et al. Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing. Int J Pharm 2003;264:1-14 (Pubitemid 37297629)
147. Jain AC, Aungst BJ, Adeyeye MC. Development and in vivo evaluation of buccal tablets prepared using danazol-sulfobutylether 7 beta-cyclodextrin (SBE 7) complexes. J Pharm Sci 2002;91:1659-68 (Pubitemid 34680228)
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150. Alur HH, Pather SI, Mitra AK., et al. Transmucosal sustained-delivery of chlorpheniramine maleate in rabbits using a novel, natural mucoadhesive gum as an excipient in buccal tablets. Int J Pharm 1999;188:1-10 (Pubitemid 29472454)
151. Vyas SP, Jain CP. Bioadhesive polymer-grafted starch microspheres bearing isosorbide dinitrate for buccal administration. J Microencapsul 1992;9:457-64
152. Satheesh Madhav NV, Uma Shankar MS. A novel smart gentamicin loaded bioplates using Cordia dichotoma fruit pulp. Proceedings of Indian pharmaceutical Congress; 23 - 25 December 2007; BHU
153. Semwal R, Semwal DK, Badoni R, et al. Targeted drug nanoparticles: an emphasis on self assembled polymeric system. J Med Sci 2010;10:130-7
154. Satheesh Madhav NV, Uma Shankar MS, Hossain E. Isolation and characterization of novel polymer from Sesamum Indicum seeds. Proceedings of emerging applications of surface science at Department of Chemical Engineering IIT; 15 November 2005; Delhi
155. Satheesh Madhav NV, Uma Shankar MS, Hossain E, et al. Formulation and evaluation of ofloxacin tablets using a novel processing agent from gaujava. Proceedings of 16th conference of Society for Biomaterial and Artificial Organs, held at Centre for Biomedical Engineering, IIT; 24 - 26 February 2006; Delhi
156. Satheesh Madhav NV, Uma Shankar MS, Hossain E. Preparation and Characterization of Sodium salt of usa paradisiacal Polymer. Proceedings of 10th International Conference of ISCB on Drug Discovery: Perspectives and Challenges held at Central Drug Research Institute; 24 - 25 February 2006; Lucknow
157. Satheesh Madhav NV, Uma Shankar MS, Hossain E. Characterization of novel surfactabality of a biopolymer isolated from Cocos nucifera. Proceedings of 10th international conference of ISCB on drug discovery: perspectives and challenges held at Central Drug Research Institute; 24 - 25 February 2006; Lucknow
158. Satheesh Madhav NV, Uma Shankar MS, Hossain E. A novel gum from the leaves of Bombax malabaricum. Proceedings of 10th international conference of ISCB on drug discovery: perspectives and challenges held at Central Drug Research Institute; 24 - 25 February 2006; Lucknow
159. Satheesh Madhav NV, Uma Shankar MS, Hossain E. A novel biomaterial from kernels of Helianthus annus. Proceedings of 4th International TRI/Princeton Workshop on Characterization of Porous Material from Angstroms to Millimeter; 21 - 23 June 2006; Princeton, NJ, USA
160. Satheesh Madhav NV,Uma Shankar MS. A novel biomaterial from Mangifera indica and its pharmaceutical applications. Proceedings of international conference on drug discovery research ISCBC-2007; 24 - 26 February 2007; Aurangabad
161. Satheesh Madhav NV, Uma Shankar MS. Isolation and characterization of a novel biomaterial from Lotus corniculatus. Proceedings of international conference on drug discovery research ISCBC-2007; 24 - 26 February 2007; Aurangabad
162. Satheesh Madhav NV, Uma Shankar MS. Isolation and characterization of novel biomaterial from Cajanus indicus. Proceedings of international conference on drug discovery research ISCBC-2007; 24 - 26 February 2007; Aurangabad
163. Satheesh Madhav NV, Uma Shankar MS. A novel bioadhesive material from Logelaria siceraria. Proceedings of international conference on drug discovery research ISCBC-2007; 24 - 26 February 2007; Aurangabad
164. Satheesh Madhav NV, Uma Shankar MS. Drug loaded biomicrodwarfs using a novel biopolymeric material from Arahcis hypogea seeds. Proceedings of International conference on Processing Pharmaceutical at Polymers Rapra Technology's Pharmaceutical Polymers Conference; 20 - 21 June 2007; Switzerland
165. Satheesh NV, Uma Shankar MS, Maurya A. A smart bioplate from Lallimantia royalena seeds fro trans-soft palatal delivery. Proceedings of International Conference on Innovations in Drug Delivery from Biomaterial to Devices; September 30 - October 3 2008; Naples, Italy
166. Satheesh Madhav NV, Ojha A. A novel potential bio-binder from Annona squamosa fruit pulp. Proceedings of Indian Pharmaceutical congress; 12 - 14 December 2008;; Delhi
167. Satheesh Madhav NV, Ojha A. Formulation of novel bio-dispersible film using Gravia oppositifolia bio-material. Proceedings of Indian Pharmaceutical congress; 12 - 14 December 2008; Delhi
168. Satheesh Madhav NV, Ojha A. A novel bio-mucoadhesant from Cucurbita maxima fruit pulp. Proceedings of Indian Pharmaceutical congress; 12 - 14 December 2008; Delhi
169. Satheesh Madhav NV, Ojha A. Development of a novel mucoadhesive bioplate using Psidium guajava biomaterial from trans-soft palatal. Proceedings of Indian Pharmaceutical congress; 12 - 14 December 2008; Delhi
170. Satheesh Madhav NV, Tangri P, Khurana S. Formulation and evaluation of zidovudine bio-micro dwarfs using anovel bio-muco resident from Artocarpus heterophyllus. 61st I.P.C; 2009. Ahmedabad
171. Manganaro AM, Wertz PW. The effects of permeabilizers on the in vitro penetration of propranolol through porcine buccal epithelium. Mil Med 1996;161:669-72 (Pubitemid 26386771)
172. Hoogstraate AJ, Senel S, Cullander C, et al. Effects of bile salts on transport rates and routes of FTIC-labelled compounds across porcine buccal epithelium in vitro. J Control Release 1996;40:211-21 (Pubitemid 26238373)
173. Wolany GJM, Munzer J, Rummelt A, et al. Buccal absorption of Sandostatin (octreotide) in conscious beagle dogs. Proc Int Symp Control Release Bioact Mater 1990;17:224-5
174. Nakane S, Kakumoto M, Yulimatsu K, et al. Oramucosal delivery of LHRH: Pharmacokinetic studies of controlled and enhanced transmucosal permeation. Pharm Dev Technol 1996;1:251-9
175. Steward A, Bayley DL, Howes C. The effect of enhancers on the buccal absorption of hybrid (BDBB) alpha-interferon. Int J Pharm 1994;104:145-9 (Pubitemid 24073698)
176. Gandhi R, Robinson J. Mechanisms of penetration enhancement for transbuccal delivery of salicylic acid. Int J Pharm 1992;85:129-40
177. Aungst BJ, Rogers NJ, Shefter E. Comparison of nasal, rectal, buccal, sublingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter. J Pharmacol Exp Ther 1988;244:23-7 (Pubitemid 18042357)