-
1
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
-
DOI 10.1016/S0140-6736(06)68770-9, PII S0140673606687709
-
Lopez AD, Mathers CD, Ezzati M, et al. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet. 2006;367(9524):1747-57. (Pubitemid 43767064)
-
(2006)
Lancet
, vol.367
, Issue.9524
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
2
-
-
77649126524
-
Heart disease and stroke statistics-2010 update: A report from the American heart association
-
Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics-2010 update: a report from the American heart association. Circulation. 2010;121(7):e46-e215.
-
(2010)
Circulation.
, vol.121
, Issue.7
-
-
Lloyd-Jones, D.1
Adams, R.J.2
Brown, T.M.3
-
3
-
-
0037031061
-
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
-
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360(9326):7-22.
-
(2002)
Lancet.
, vol.360
, Issue.9326
, pp. 7-22
-
-
-
4
-
-
26244432388
-
Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
-
Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366(9493):1267-78.
-
(2005)
Lancet.
, vol.366
, Issue.9493
, pp. 1267-1278
-
-
Baigent, C.1
Keech, A.2
Kearney, P.M.3
-
5
-
-
27744522317
-
The forgotten majority: Unfinished business in cardiovascular risk reduction
-
DOI 10.1016/j.jacc.2005.07.006, PII S0735109705015688
-
Libby P. The forgotten majority: unfinished business in cardiovascular risk reduction. J Am Coll Cardiol. 2005;46(7):1225-8. (Pubitemid 41615541)
-
(2005)
Journal of the American College of Cardiology
, vol.46
, Issue.7
, pp. 1225-1228
-
-
Libby, P.1
-
6
-
-
0042195833
-
Major Risk Factors as Antecedents of Fatal and Nonfatal Coronary Heart Disease Events
-
DOI 10.1001/jama.290.7.891
-
Greenland P, Knoll MD, Stamler J, et al. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA. 2003;290(7):891-7. (Pubitemid 37430460)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.7
, pp. 891-897
-
-
Greenland, P.1
Knoll, M.D.2
Stamler, J.3
Neaton, J.D.4
Dyer, A.R.5
Garside, D.B.6
Wilson, P.W.7
-
7
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature. 2000;407(6801):233-41.
-
(2000)
Nature.
, vol.407
, Issue.6801
, pp. 233-241
-
-
Lusis, A.J.1
-
8
-
-
14944358734
-
Cardiovascular death in rheumatoid arthritis: A population-based study
-
DOI 10.1002/art.20878
-
Maradit-Kremers H, Nicola PJ, Crowson CS, et al. Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis Rheum. 2005;52(3):722-32. (Pubitemid 40365093)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.3
, pp. 722-732
-
-
Maradit-Kremers, H.1
Nicola, P.J.2
Crowson, C.S.3
Ballman, K.V.4
Gabriel, S.E.5
-
9
-
-
0347922145
-
Premature coronaryartery atherosclerosis in systemic lupus erythematosus
-
DOI 10.1056/NEJMoa035611
-
Asanuma Y, Oeser A, Shintani AK, et al. Premature coronaryartery atherosclerosis in systemic lupus erythematosus. N Engl J Med. 2003;349(25):2407-15. (Pubitemid 37542989)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.25
, pp. 2407-2415
-
-
Asanuma, Y.1
Oeser, A.2
Shintani, A.K.3
Turner, E.4
Olsen, N.5
Fazio, S.6
Linton, M.F.7
Raggi, P.8
Stein, C.M.9
-
10
-
-
0035955760
-
Novel clinical markers of vascular wall inflammation
-
Blake GJ, Ridker PM. Novel clinical markers of vascular wall inflammation. Circ Res. 2001;89(9):763-71. (Pubitemid 34633846)
-
(2001)
Circulation Research
, vol.89
, Issue.9
, pp. 763-771
-
-
Blake, G.J.1
Ridker, P.M.2
-
11
-
-
73449130797
-
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis
-
Kaptoge S, Di Angelantonio E, Lowe G, et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet. 2010;375(9709):132-40.
-
(2010)
Lancet.
, vol.375
, Issue.9709
, pp. 132-140
-
-
Kaptoge, S.1
Di Angelantonio, E.2
Lowe, G.3
-
12
-
-
46249124299
-
The time for cardiovascular inflammation reduction trials has arrived: How low to go for hsCRP?
-
Ridker PM. The time for cardiovascular inflammation reduction trials has arrived: how low to go for hsCRP? Arterioscler Thromb Vasc Biol. 2008;28(7):1222-4.
-
(2008)
Arterioscler Thromb Vasc Biol.
, vol.28
, Issue.7
, pp. 1222-1224
-
-
Ridker, P.M.1
-
13
-
-
80051765806
-
Association between highsensitivity C-reactive protein and coronary plaque subtypes assessed by 64-slice coronary computed tomography angiography in an asymptomatic population
-
Rubin J, Chang HJ, Nasir K, et al. Association between highsensitivity C-reactive protein and coronary plaque subtypes assessed by 64-slice coronary computed tomography angiography in an asymptomatic population. Circ Cardiovasc Imaging. 2011;4(3):201-9.
-
(2011)
Circ Cardiovasc Imaging.
, vol.4
, Issue.3
, pp. 201-209
-
-
Rubin, J.1
Chang, H.J.2
Nasir, K.3
-
14
-
-
0032169240
-
Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels
-
Ridker PM, Rifai N, Pfeffer MA, et al. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events (CARE) investigators. Circulation. 1998;98(9):839-44. (Pubitemid 28397432)
-
(1998)
Circulation
, vol.98
, Issue.9
, pp. 839-844
-
-
Ridker, P.M.1
Rifai, N.2
Pfeffer, M.A.3
Sacks, F.M.4
Moye, L.A.5
Goldman, S.6
Flaker, G.C.7
Braunwald, E.8
-
15
-
-
11344279659
-
C-reactive protein levels and outcomes after statin therapy
-
DOI 10.1056/NEJMoa042378
-
Ridker PM, Cannon CP, Morrow D, et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med. 2005;352(1):20-8. (Pubitemid 40075677)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.1
, pp. 20-28
-
-
Ridker, P.M.1
Cannon, C.P.2
Morrow, D.3
Rifai, N.4
Rose, L.M.5
McCabe, C.H.6
Pfeffer, M.A.7
Braunwald, E.8
-
16
-
-
0032572086
-
Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS
-
DOI 10.1001/jama.279.20.1615
-
Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas coronary atherosclerosis prevention study. JAMA. 1998;279(20):1615-22. (Pubitemid 28248586)
-
(1998)
Journal of the American Medical Association
, vol.279
, Issue.20
, pp. 1615-1622
-
-
Downs, J.R.1
Clearfield, M.2
Weis, S.3
Whitney, E.4
Shapiro, D.R.5
Beere, P.A.6
Langendorfer, A.7
Stein, E.A.8
Kruyer, W.9
Gotto Jr., A.M.10
-
17
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated Creactive protein
-
Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated Creactive protein. N Engl J Med. 2008;359(21):2195-207.
-
(2008)
N Engl J Med.
, vol.359
, Issue.21
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
-
18
-
-
67949124665
-
Testing the inflammatory hypothesis of atherothrombosis: Scientific rationale for the cardiovascular inflammation reduction trial (CIRT)
-
Ridker PM. Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT). J Thromb Haemost. 2009;7 Suppl 1:332-9. This prospective trial examined the impact of low-dose metothraxate on cardiovascular endpoints.
-
(2009)
J Thromb Haemost.
, vol.7
, Issue.SUPPL. 1
, pp. 332-339
-
-
Ridker, P.M.1
-
19
-
-
80053644777
-
Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: Rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)
-
Ridker PM, Thuren T, Zalewski A, Libby P. Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS). Am Heart J. 2011;162(4):597-605. This prospective trial studied the impact of canakinumab on cardiovascular endpoints.
-
(2011)
Am Heart J.
, vol.162
, Issue.4
, pp. 597-605
-
-
Ridker, P.M.1
Thuren, T.2
Zalewski, A.3
Libby, P.4
-
20
-
-
0029079926
-
Decreased atherosclerosis in mice deficient in bothmacrophage colony-stimulating factor (op) and apolipoprotein e
-
Smith JD, Trogan E, Ginsberg M, et al. Decreased atherosclerosis in mice deficient in bothmacrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci U S A. 1995;92(18):8264-8.
-
(1995)
Proc Natl Acad Sci U S A.
, vol.92
, Issue.18
, pp. 8264-8268
-
-
Smith, J.D.1
Trogan, E.2
Ginsberg, M.3
-
21
-
-
0032525907
-
Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor-deficient mice
-
Rajavashisth T, Qiao JH, Tripathi S, et al. Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptordeficient mice. J Clin Invest. 1998;101(12):2702-10. (Pubitemid 28294579)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.12
, pp. 2702-2710
-
-
Rajavashisth, T.1
Qiao, J.-H.2
Tripathi, S.3
Tripathi, J.4
Mishra, N.5
Hua, M.6
Wang, X.-P.7
Loussararian, A.8
Clinton, S.9
Libby, P.10
Lusis, A.11
-
22
-
-
33845989083
-
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
-
DOI 10.1172/JCI28549
-
Tacke F, Alvarez D, Kaplan TJ, et al. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest. 2007;117(1):185-94. (Pubitemid 46048465)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 185-194
-
-
Tacke, F.1
Alvarez, D.2
Kaplan, T.J.3
Jakubzick, C.4
Spanbroek, R.5
Llodra, J.6
Garin, A.7
Liu, J.8
Mack, M.9
Van Rooijen, N.10
Lira, S.A.11
Habenicht, A.J.12
Randolph, G.J.13
-
23
-
-
33645891172
-
Cytokines in atherosclerosis: Pathogenic and regulatory pathways
-
Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev. 2006;86(2):515-81.
-
(2006)
Physiol Rev.
, vol.86
, Issue.2
, pp. 515-581
-
-
Tedgui, A.1
Mallat, Z.2
-
24
-
-
0035957575
-
Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-leiden transgenic mice
-
van Vlijmen BJ, Gerritsen G, Franken AL, et al. Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-leiden transgenic mice. Circ Res. 2001;88(8):780-6. (Pubitemid 32429973)
-
(2001)
Circulation Research
, vol.88
, Issue.8
, pp. 780-786
-
-
Van Vlijmen, B.J.M.1
Gerritsen, G.2
Franken, A.L.3
Boesten, L.S.M.4
Kockx, M.M.5
Gijbels, M.J.6
Vierboom, M.P.7
Van Eck, M.8
Van De Water, B.9
Van Berkel, T.J.C.10
Havekes, L.M.11
-
25
-
-
0028946245
-
Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma
-
Ball RY, Stowers EC, Burton JH, et al. Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. Atherosclerosis. 1995;114(1):45-54.
-
(1995)
Atherosclerosis.
, vol.114
, Issue.1
, pp. 45-54
-
-
Ball, R.Y.1
Stowers, E.C.2
Burton, J.H.3
-
26
-
-
66349092815
-
Mechanisms and consequences of macrophage apoptosis in atherosclerosis
-
Seimon T, Tabas I. Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J Lipid Res. 2009;50(Suppl): S382-7.
-
(2009)
J Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Seimon, T.1
Tabas, I.2
-
27
-
-
0032560637
-
Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: A potential mechanism of lesion stabilization
-
Aikawa M, Rabkin E, Okada Y, et al. Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation. 1998;97(24):2433-44. (Pubitemid 28278188)
-
(1998)
Circulation
, vol.97
, Issue.24
, pp. 2433-2444
-
-
Aikawa, M.1
Rabkin, E.2
Okada, Y.3
Voglic, S.J.4
Clinton, S.K.5
Brinckerhoff, C.E.6
Sukhova, G.K.7
Libby, P.8
-
28
-
-
51649101109
-
Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages
-
Johnson JL, Sala-Newby GB, Ismail Y, et al. Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages. Arterioscler Thromb Vasc Biol. 2008;28(9):1647-53.
-
(2008)
Arterioscler Thromb Vasc Biol.
, vol.28
, Issue.9
, pp. 1647-1653
-
-
Johnson, J.L.1
Sala-Newby, G.B.2
Ismail, Y.3
-
29
-
-
77951079412
-
Gene expression and 18FDG uptake in atherosclerotic carotid plaques
-
Pedersen SF, Graebe M, Fisker Hag AM, et al. Gene expression and 18FDG uptake in atherosclerotic carotid plaques. Nucl Med Commun. 2010;31(5):423-9.
-
(2010)
Nucl Med Commun.
, vol.31
, Issue.5
, pp. 423-429
-
-
Pedersen, S.F.1
Graebe, M.2
Fisker Hag, A.M.3
-
31
-
-
0026643681
-
Macrophage differentiation in atherosclerosis. An in situ immunohistochemical analysis in humans
-
van der Wal AC, Das PK, Tigges AJ, Becker AE. Macrophage differentiation in atherosclerosis. An in situ immunohistochemical analysis in humans. Am J Pathol. 1992;141(1):161-8.
-
(1992)
Am J Pathol.
, vol.141
, Issue.1
, pp. 161-168
-
-
Van Der Wal, A.C.1
Das, P.K.2
Tigges, A.J.3
Becker, A.E.4
-
32
-
-
0037265240
-
Alternative activation of macrophages
-
DOI 10.1038/nri978
-
Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3(1):23-35. (Pubitemid 37328697)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.1
, pp. 23-35
-
-
Gordon, S.1
-
33
-
-
38449102676
-
Macrophage activation and polarization
-
DOI 10.2741/2692
-
Martinez FO, Sica A, Mantovani A, Locati M. Macrophage activation and polarization. Front Biosci. 2008;13:453-61. (Pubitemid 351599757)
-
(2008)
Frontiers in Bioscience
, vol.13
, Issue.2
, pp. 453-461
-
-
Martinez, F.O.1
Sica, A.2
Mantovani, A.3
Locati, M.4
-
34
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8(12):958-69.
-
(2008)
Nat Rev Immunol.
, vol.8
, Issue.12
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
35
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol. 2011;11(11):723-37.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
36
-
-
35748964164
-
Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection
-
Loke P, Gallagher I, Nair MG, et al. Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection. J Immunol. 2007;179(6):3926-36.
-
(2007)
J Immunol.
, vol.179
, Issue.6
, pp. 3926-3936
-
-
Loke, P.1
Gallagher, I.2
Nair, M.G.3
-
37
-
-
34247626970
-
Chitin induces accumulation in tissue of innate immune cells associated with allergy
-
DOI 10.1038/nature05746, PII NATURE05746
-
Reese TA, Liang HE, Tager AM, et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. 2007;447(7140):92-6. (Pubitemid 46685837)
-
(2007)
Nature
, vol.447
, Issue.7140
, pp. 92-96
-
-
Reese, T.A.1
Liang, H.-E.2
Tager, A.M.3
Luster, A.D.4
Van Rooijen, N.5
Voehringer, D.6
Locksley, R.M.7
-
38
-
-
0035576207
-
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
-
HesseM, ModolellM, La Flamme AC, et al. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of Larginine metabolism. J Immunol. 2001;167(11):6533-44. (Pubitemid 33081589)
-
(2001)
Journal of Immunology
, vol.167
, Issue.11
, pp. 6533-6544
-
-
Hesse, M.1
Modolell, M.2
La Flamme, A.C.3
Schito, M.4
Fuentes, J.M.5
Cheever, A.W.6
Pearce, E.J.7
Wynn, T.A.8
-
39
-
-
44449096726
-
IL-10: The master regulator of immunity to infection
-
Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol. 2008;180(9):5771-7.
-
(2008)
J Immunol.
, vol.180
, Issue.9
, pp. 5771-5777
-
-
Couper, K.N.1
Blount, D.G.2
Riley, E.M.3
-
40
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity. 2010;32(5):593-604.
-
(2010)
Immunity.
, vol.32
, Issue.5
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
41
-
-
69449085100
-
GM-CSF- and MCSF- dependent macrophage phenotypes display differential dependence on type i interferon signaling
-
Fleetwood AJ, Dinh H, Cook AD, et al. GM-CSF- and MCSF- dependent macrophage phenotypes display differential dependence on type I interferon signaling. J Leukoc Biol. 2009;86(2):411-21.
-
(2009)
J Leukoc Biol.
, vol.86
, Issue.2
, pp. 411-421
-
-
Fleetwood, A.J.1
Dinh, H.2
Cook, A.D.3
-
42
-
-
34247124840
-
Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: Implications for CSF blockade in inflammation
-
Fleetwood AJ, Lawrence T, Hamilton JA, Cook AD. Granulocytemacrophage colony-stimulating factor (CSF) and macrophage CSFdependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation. J Immunol. 2007;178(8):5245-52. (Pubitemid 46595309)
-
(2007)
Journal of Immunology
, vol.178
, Issue.8
, pp. 5245-5252
-
-
Fleetwood, A.J.1
Lawrence, T.2
Hamilton, J.A.3
Cook, A.D.4
-
43
-
-
77954507872
-
CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages
-
Gleissner CA, Shaked I, Little KM, Ley K. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. J Immunol. 2010;184(9):4810-8.
-
(2010)
J Immunol.
, vol.184
, Issue.9
, pp. 4810-4818
-
-
Gleissner, C.A.1
Shaked, I.2
Little, K.M.3
Ley, K.4
-
44
-
-
77957260181
-
Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2
-
Kadl A, Meher AK, Sharma PR, et al. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res. 2010;107(6):737-46.
-
(2010)
Circ Res.
, vol.107
, Issue.6
, pp. 737-746
-
-
Kadl, A.1
Meher, A.K.2
Sharma, P.R.3
-
45
-
-
79551654684
-
Distinct macrophage phenotypes contribute to kidney injury and repair
-
Lee S, Huen S, Nishio H, et al. Distinct macrophage phenotypes contribute to kidney injury and repair. J Am Soc Nephrol. 2011;22(2):317-26. This article shows macrophage plasticity in a transient in vivo model of inflammation.
-
(2011)
J Am Soc Nephrol.
, vol.22
, Issue.2
, pp. 317-326
-
-
Lee, S.1
Huen, S.2
Nishio, H.3
-
46
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
DOI 10.1172/JCI29881
-
Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest. 2007;117(1):175-84. (Pubitemid 46048464)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
47
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
Stienstra R, van Diepen JA, Tack CJ, et al. Inflammasome is a central player in the induction of obesity and insulin resistance. Proc Natl Acad Sci U S A. 2011;108(37):15324-9.
-
(2011)
Proc Natl Acad Sci U S A.
, vol.108
, Issue.37
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
-
48
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol. 2011;11 (11):738-49.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.3
-
49
-
-
77949499329
-
Macrophage heterogeneity: Relevance and functional implications in atherosclerosis
-
Stoger JL, Goossens P, deWinther MP. Macrophage heterogeneity: relevance and functional implications in atherosclerosis. Curr Vasc Pharmacol. 2010;8(2):233-48.
-
(2010)
Curr Vasc Pharmacol.
, vol.8
, Issue.2
, pp. 233-248
-
-
Stoger, J.L.1
Goossens, P.2
Dewinther, M.P.3
-
50
-
-
70349581878
-
Macrophage diversity and polarization in atherosclerosis: A question of balance
-
Mantovani A, Garlanda C, Locati M. Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol. 2009;29(10):1419-23.
-
(2009)
Arterioscler Thromb Vasc Biol.
, vol.29
, Issue.10
, pp. 1419-1423
-
-
Mantovani, A.1
Garlanda, C.2
Locati, M.3
-
51
-
-
80155214124
-
Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation
-
Wolfs IM, Donners MM, de Winther MP. Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation. Thromb Haemost. 2011;106(5):763-71.
-
(2011)
Thromb Haemost.
, vol.106
, Issue.5
, pp. 763-771
-
-
Wolfs, I.M.1
Donners, M.M.2
De Winther, M.P.3
-
52
-
-
77952532171
-
Macrophage plasticity in experimental atherosclerosis
-
Khallou-Laschet J, Varthaman A, Fornasa G, et al. Macrophage plasticity in experimental atherosclerosis. PLoS One. 2010;5(1): e8852.
-
(2010)
PLoS One.
, vol.5
, Issue.1
-
-
Khallou-Laschet, J.1
Varthaman, A.2
Fornasa, G.3
-
53
-
-
79952736069
-
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques
-
Feig JE, Parathath S, Rong JX, et al. Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques. Circulation. 2011;123(9):989-98. This article very elegantly shows that induction of atherosclerosis regression by reversal of hyperlipidemia leads to a shift from CAM macrophages to an AAM phenotype in atherosclerotic lesions.
-
(2011)
Circulation.
, vol.123
, Issue.9
, pp. 989-998
-
-
Feig, J.E.1
Parathath, S.2
Rong, J.X.3
-
54
-
-
84861229760
-
Cytokine profiling in culture reveals a predominance of M1 macrophage polarisation in symptomatic carotid plaques
-
Shalhoub J, Cross A, Allin D, et al. Cytokine profiling in culture reveals a predominance of M1 macrophage polarisation in symptomatic carotid plaques. Presented on the BSCR Spring Meeting. 2010;96(17):e23-e23.
-
(2010)
Presented on the BSCR Spring Meeting.
, vol.96
, Issue.17
-
-
Shalhoub, J.1
Cross, A.2
Allin, D.3
-
55
-
-
79960065980
-
Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue
-
Hirata Y, Tabata M, Kurobe H, et al. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol. 2011;58(3):248-55.
-
(2011)
J Am Coll Cardiol.
, vol.58
, Issue.3
, pp. 248-255
-
-
Hirata, Y.1
Tabata, M.2
Kurobe, H.3
-
56
-
-
79955144904
-
Innate immunity and monocyte-macrophage activation in atherosclerosis
-
(Lond).
-
Shalhoub J, Falck-Hansen MA, Davies AH, Monaco C. Innate immunity and monocyte-macrophage activation in atherosclerosis. J Inflamm (Lond). 2011;8:9.
-
(2011)
J Inflamm
, vol.8
, pp. 9
-
-
Shalhoub, J.1
Falck-Hansen, M.A.2
Davies, A.H.3
Monaco, C.4
-
57
-
-
79953678939
-
Obstacles and opportunities for understanding macrophage polarization
-
Murray PJ, Wynn TA. Obstacles and opportunities for understanding macrophage polarization. J Leukoc Biol. 2011;89(4):557-63.
-
(2011)
J Leukoc Biol.
, vol.89
, Issue.4
, pp. 557-563
-
-
Murray, P.J.1
Wynn, T.A.2
-
58
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol. 2011;11(11):750-61.
-
(2011)
Nat Rev Immunol.
, vol.11
, Issue.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
59
-
-
10744230385
-
Interferon-γ regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways
-
DOI 10.1042/BJ20030260
-
Soler C, Felipe A, Garcia-Manteiga J, et al. Interferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways. Biochem J. 2003;375(Pt 3):777-83. (Pubitemid 37433528)
-
(2003)
Biochemical Journal
, vol.375
, Issue.3
, pp. 777-783
-
-
Soler, C.1
Felipe, A.2
Garcia-Manteiga, J.3
Serra, M.4
Guillen-Gomez, E.5
Casado, F.J.6
MacLeod, C.7
Modolell, M.8
Pastor-Anglada, M.9
Celada, A.10
-
60
-
-
34250316051
-
Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development
-
DOI 10.1161/CIRCULATIONAHA.107.696922
-
Agrawal S, Febbraio M, Podrez E, et al. Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development. Circulation. 2007;115(23):2939-47. (Pubitemid 46912097)
-
(2007)
Circulation
, vol.115
, Issue.23
, pp. 2939-2947
-
-
Agrawal, S.1
Febbraio, M.2
Podrez, E.3
Cathcart, M.K.4
Stark, G.R.5
Chisolm, G.M.6
-
61
-
-
39449103260
-
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo
-
DOI 10.1161/CIRCULATIONAHA.107.711275
-
Lim WS, Timmins JM, Seimon TA, et al. Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. Circulation. 2008;117(7):940-51. (Pubitemid 351272592)
-
(2008)
Circulation
, vol.117
, Issue.7
, pp. 940-951
-
-
Lim, W.-S.1
Timmins, J.M.2
Seimon, T.A.3
Sadler, A.4
Kolodgie, F.D.5
Virmani, R.6
Tabas, I.7
-
62
-
-
70350435962
-
Epigenetic regulation of the alternatively activated macrophage phenotype
-
Ishii M, Wen H, Corsa CA, et al. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood. 2009;114 (15):3244-54.
-
(2009)
Blood.
, vol.114
, Issue.15
, pp. 3244-3254
-
-
Ishii, M.1
Wen, H.2
Corsa, C.A.3
-
63
-
-
0035665020
-
Possible new role for NF-κB in the resolution of inflammation
-
DOI 10.1038/nm1201-1291
-
Lawrence T, Gilroy DW, Colville-Nash PR, Willoughby DA. Possible new role for NF-kappaB in the resolution of inflammation. Nat Med. 2001;7(12):1291-7. (Pubitemid 34007932)
-
(2001)
Nature Medicine
, vol.7
, Issue.12
, pp. 1291-1297
-
-
Lawrence, T.1
Gilroy, D.W.2
Colville-Nash, P.R.3
Willoughby, D.A.4
-
64
-
-
13344261982
-
Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion
-
Brand K, Page S, Rogler G, et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest. 1996;97(7):1715-22. (Pubitemid 26105480)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.7
, pp. 1715-1722
-
-
Brand, K.1
Page, S.2
Rogler, G.3
Bartsch, A.4
Brandl, R.5
Knuechel, R.6
Page, M.7
Kaltschmidt, C.8
Baeuerle, P.A.9
Neumeier, D.10
-
65
-
-
45149087674
-
An antiinflammatory role for IKKβ through the inhibition of "classical" macrophage activation
-
DOI 10.1084/jem.20080124
-
Fong CH, Bebien M, Didierlaurent A, et al. An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. J Exp Med. 2008;205(6):1269-76. (Pubitemid 351831484)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1269-1276
-
-
Fong, C.H.Y.1
Bebien, M.2
Didierlaurent, A.3
Nebauer, R.4
Hussell, T.5
Broide, D.6
Karin, M.7
Lawrence, T.8
-
66
-
-
0346727295
-
Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice
-
DOI 10.1172/JCI200318580
-
Kanters E, Pasparakis M, Gijbels MJ, et al. Inhibition of NFkappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2003;112 (8):1176-85. (Pubitemid 38056294)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.8
, pp. 1176-1185
-
-
Kanters, E.1
Pasparakis, M.2
Gijbels, M.J.J.3
Vergouwe, M.N.4
Partouns-Hendriks, I.5
Fijneman, R.J.A.6
Clausen, B.E.7
Forster, I.8
Kockx, M.M.9
Rajewsky, K.10
Kraal, G.11
Hofker, M.H.12
De Winther, M.P.J.13
-
67
-
-
70349275277
-
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB
-
Porta C, Rimoldi M, Raes G, et al. Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A. 2009;106(35):14978-83.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, Issue.35
, pp. 14978-14983
-
-
Porta, C.1
Rimoldi, M.2
Raes, G.3
-
68
-
-
1442327145
-
Hematopoietic NF-κB1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype
-
DOI 10.1182/blood-2003-05-1450
-
Kanters E, Gijbels MJ, van der Made I, et al. Hematopoietic NFkappaB1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype. Blood. 2004;103(3):934-40. (Pubitemid 38129553)
-
(2004)
Blood
, vol.103
, Issue.3
, pp. 934-940
-
-
Kanters, E.1
Gijbels, M.J.J.2
Van Der Made, I.3
Vergouwe, M.N.4
Heeringa, P.5
Kraal, G.6
Hofker, M.H.7
De Winther, M.P.J.8
-
69
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh T, Takeuchi O, Vandenbon A, et al. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol. 2010;11(10):936-44.
-
(2010)
Nat Immunol.
, vol.11
, Issue.10
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
-
70
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
DOI 10.1038/nature03308
-
Takaoka A, Yanai H, Kondo S, et al. Integral role of IRF-5 in the gene induction programme activated by toll-like receptors. Nature. 2005;434(7030):243-9. (Pubitemid 40388058)
-
(2005)
Nature
, vol.434
, Issue.7030
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
Mizutani, T.6
Kano, S.-I.7
Honda, K.8
Ohba, Y.9
Mak, T.W.10
Taniguchi, T.11
-
71
-
-
79951671510
-
IRF5 Promotes inflammatory macrophage polarization and TH1-TH17 responses
-
Krausgruber T, Blazek K, Smallie T, et al. IRF5 Promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol. 2011;12(3):231-8.
-
(2011)
Nat Immunol.
, vol.12
, Issue.3
, pp. 231-238
-
-
Krausgruber, T.1
Blazek, K.2
Smallie, T.3
-
72
-
-
0142156744
-
Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ-primed IL-12 Production by IFN Regulatory Factor 1
-
DOI 10.1084/jem.20030026
-
Liu J, Cao S, Herman LM, Ma X. Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1. J Exp Med. 2003;198(8):1265-76. (Pubitemid 37323391)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.8
, pp. 1265-1276
-
-
Liu, J.1
Cao, S.2
Herman, L.M.3
Ma, X.4
-
73
-
-
27744524477
-
Active repression of IFN regulatory factor-1-mediated transactivation by IFN regulatory factor-4
-
DOI 10.1093/intimm/dxh324
-
Yoshida K, Yamamoto K, Kohno T, et al. Active repression of IFN regulatory factor-1-mediated transactivation by IFN regulatory factor-4. Int Immunol. 2005;17(11):1463-71. (Pubitemid 41631322)
-
(2005)
International Immunology
, vol.17
, Issue.11
, pp. 1463-1471
-
-
Yoshida, K.1
Yamamoto, K.2
Kohno, T.3
Hironaka, N.4
Yasui, K.5
Kojima, C.6
Mukae, H.7
Kadota, J.-I.8
Suzuki, S.9
Honma, K.10
Kohno, S.11
Matsuyama, T.12
-
74
-
-
77953540057
-
Inhibition of IFN regulatory factor-1 down-regulate Th1 cell function in patients with acute coronary syndrome
-
Guo M, Mao X, Ji Q, et al. Inhibition of IFN regulatory factor-1 down-regulate Th1 cell function in patients with acute coronary syndrome. J Clin Immunol. 2010;30(2):241-52.
-
(2010)
J Clin Immunol.
, vol.30
, Issue.2
, pp. 241-252
-
-
Guo, M.1
Mao, X.2
Ji, Q.3
-
75
-
-
34347354309
-
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 2007;447(7148):1116-20. (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
76
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
DOI 10.1016/j.cmet.2007.06.010, PII S1550413107001660
-
Bouhlel MA, Derudas B, Rigamonti E, et al. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab. 2007;6 (2):137-43. (Pubitemid 47189091)
-
(2007)
Cell Metabolism
, vol.6
, Issue.2
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dievart, R.4
Brozek, J.5
Haulon, S.6
Zawadzki, C.7
Jude, B.8
Torpier, G.9
Marx, N.10
Staels, B.11
Chinetti-Gbaguidi, G.12
-
77
-
-
80052150672
-
LXRalpha regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8
-
Pourcet B, Feig JE, Vengrenyuk Y, et al. LXRalpha regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8. Circ Res. 2011;109(5):492-501.
-
(2011)
Circ Res.
, vol.109
, Issue.5
, pp. 492-501
-
-
Pourcet, B.1
Feig, J.E.2
Vengrenyuk, Y.3
-
78
-
-
23244451031
-
Conditional knockout of macrophage PPARγ increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice
-
DOI 10.1161/01.ATV.0000173413.31789.1a
-
Babaev VR, Yancey PG, Ryzhov SV, et al. Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2005;25(8):1647-53. (Pubitemid 41098935)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.8
, pp. 1647-1653
-
-
Babaev, V.R.1
Yancey, P.G.2
Ryzhov, S.V.3
Kon, V.4
Breyer, M.D.5
Magnuson, M.A.6
Fazio, S.7
Linton, M.F.8
-
79
-
-
80051781844
-
Macrophage LXRalpha gene therapy ameliorates atherosclerosis as well as hypertriglyceridemia in LDLR(-/-) mice
-
Li G, Biju KC, Xu X, et al. Macrophage LXRalpha gene therapy ameliorates atherosclerosis as well as hypertriglyceridemia in LDLR(-/-) mice. Gene Ther. 2011;18(8):835-41.
-
(2011)
Gene Ther.
, vol.18
, Issue.8
, pp. 835-841
-
-
Li, G.1
Biju, K.C.2
Xu, X.3
-
80
-
-
83655167182
-
Disruption of endothelial peroxisome proliferator-activated receptor gamma accelerates diet-induced atherogenesis in LDL receptor-null mice
-
Qu A, Shah YM, Manna SK, Gonzalez FJ. Disruption of endothelial peroxisome proliferator-activated receptor gamma accelerates diet-induced atherogenesis in LDL receptor-null mice. Arterioscler Thromb Vasc Biol. 2012;32(1):65-73.
-
(2012)
Arterioscler Thromb Vasc Biol.
, vol.32
, Issue.1
, pp. 65-73
-
-
Qu, A.1
Shah, Y.M.2
Manna, S.K.3
Gonzalez, F.J.4
-
81
-
-
79954802715
-
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways
-
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, et al. Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways. Circ Res. 2011;108 (8):985-95. This group (also reference 76) was the first to demonstrate CAM and AAM macrophages in human atherosclerosis and identified functional differences in macrophage lipid handling.
-
(2011)
Circ Res.
, vol.108
, Issue.8
, pp. 985-995
-
-
Chinetti-Gbaguidi, G.1
Baron, M.2
Bouhlel, M.A.3
-
82
-
-
84856947469
-
Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5
-
Buxadé M, Lunazzi G, Minguillón J, et al. Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5. JEM. 2012.
-
(2012)
JEM
-
-
Buxadé, M.1
Lunazzi, G.2
Minguillón, J.3
-
83
-
-
80052964665
-
Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation
-
Halterman JA, Kwon HM, Zargham R, et al. Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation. Arterioscler Thromb Vasc Biol. 2011;31 (10):2287-96.
-
(2011)
Arterioscler Thromb Vasc Biol.
, vol.31
, Issue.10
, pp. 2287-2296
-
-
Halterman, J.A.1
Kwon, H.M.2
Zargham, R.3
-
84
-
-
80055096913
-
Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function
-
Whyte CS, Bishop ET, Ruckerl D, et al. Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function. J Leukoc Biol. 2011;90(5):845-54.
-
(2011)
J Leukoc Biol.
, vol.90
, Issue.5
, pp. 845-854
-
-
Whyte, C.S.1
Bishop, E.T.2
Ruckerl, D.3
-
85
-
-
63449106571
-
Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis
-
Ortiz-Munoz G, Martin-Ventura JL, Hernandez-Vargas P, et al. Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(4):525-31.
-
(2009)
Arterioscler Thromb Vasc Biol.
, vol.29
, Issue.4
, pp. 525-531
-
-
Ortiz-Munoz, G.1
Martin-Ventura, J.L.2
Hernandez-Vargas, P.3
-
86
-
-
44449140105
-
Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo
-
Liu Y, Stewart KN, Bishop E, et al. Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol. 2008;180(9):6270-8.
-
(2008)
J Immunol.
, vol.180
, Issue.9
, pp. 6270-6278
-
-
Liu, Y.1
Stewart, K.N.2
Bishop, E.3
-
87
-
-
0346103717
-
Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
-
Williams L, Bradley L, Smith A, Foxwell B. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J Immunol. 2004;172(1):567-76. (Pubitemid 38020514)
-
(2004)
Journal of Immunology
, vol.172
, Issue.1
, pp. 567-576
-
-
Williams, L.1
Bradley, L.2
Smith, A.3
Foxwell, B.4
-
88
-
-
77958484570
-
AAV/hSTAT3-gene delivery lowers aortic inflammatory cell infiltration in LDLR KO mice on high cholesterol
-
Khan JA, Cao M, Kang BY, et al. AAV/hSTAT3-gene delivery lowers aortic inflammatory cell infiltration in LDLR KO mice on high cholesterol. Atherosclerosis. 2010;213(1):59-66.
-
(2010)
Atherosclerosis.
, vol.213
, Issue.1
, pp. 59-66
-
-
Khan, J.A.1
Cao, M.2
Kang, B.Y.3
-
89
-
-
70350445698
-
A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair
-
Ruffell D, Mourkioti F, Gambardella A, et al. A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proc Natl Acad Sci U S A. 2009;106(41):17475-80.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, Issue.41
, pp. 17475-17480
-
-
Ruffell, D.1
Mourkioti, F.2
Gambardella, A.3
-
90
-
-
79151484549
-
Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for kruppel-like factor 2
-
van Tits LJ, Stienstra R, van Lent PL, et al. Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for kruppel-like factor 2. Atherosclerosis. 2011;214(2):345-9.
-
(2011)
Atherosclerosis.
, vol.214
, Issue.2
, pp. 345-349
-
-
Van Tits, L.J.1
Stienstra, R.2
Van Lent, P.L.3
-
91
-
-
54449085767
-
Hemizygous deficiency of kruppel-like factor 2 augments experimental atherosclerosis
-
Atkins GB, Wang Y, Mahabeleshwar GH, et al. Hemizygous deficiency of kruppel-like factor 2 augments experimental atherosclerosis. Circ Res. 2008;103(7):690-3.
-
(2008)
Circ Res.
, vol.103
, Issue.7
, pp. 690-693
-
-
Atkins, G.B.1
Wang, Y.2
Mahabeleshwar, G.H.3
-
92
-
-
79960021457
-
Kruppel-like factor 4 regulates macrophage polarization
-
Liao X, Sharma N, Kapadia F, et al. Kruppel-like factor 4 regulates macrophage polarization. J Clin Invest. 2011;121(7):2736-49.
-
(2011)
J Clin Invest.
, vol.121
, Issue.7
, pp. 2736-2749
-
-
Liao, X.1
Sharma, N.2
Kapadia, F.3
-
93
-
-
80052172565
-
Epigenetic control of macrophage polarization
-
Takeuch O, Akira S. Epigenetic control of macrophage polarization. Eur J Immunol. 2011;41(9):2490-3.
-
(2011)
Eur J Immunol.
, vol.41
, Issue.9
, pp. 2490-2493
-
-
Takeuch, O.1
Akira, S.2
-
94
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
DOI 10.1016/j.cell.2007.08.019, PII S0092867407010823
-
De Santa F, Totaro MG, Prosperini E, et al. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell. 2007;130(6):1083-94. (Pubitemid 47410272)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
95
-
-
70350754328
-
Jmjd3 Contributes to the control of gene expression in LPS-activated macrophages
-
De Santa F, Narang V, Yap ZH, et al. Jmjd3 Contributes to the control of gene expression in LPS-activated macrophages. EMBO J. 2009;28(21):3341-52.
-
(2009)
EMBO J.
, vol.28
, Issue.21
, pp. 3341-3352
-
-
De Santa, F.1
Narang, V.2
Zh, Y.3
-
96
-
-
82955247088
-
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
-
Mullican SE, Gaddis CA, Alenghat T, et al. Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev. 2011;25(23):2480-8.
-
(2011)
Genes Dev.
, vol.25
, Issue.23
, pp. 2480-2488
-
-
Mullican, S.E.1
Gaddis, C.A.2
Alenghat, T.3
-
97
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, Jeffrey KL, Schaefer U, et al. Suppression of inflammation by a synthetic histone mimic. Nature. 2010;468 (7327):1119-23. This article is the first to demonstrate that pharmacologic disruption of chromatin complexes can be used to inhibit inflammatory responses.
-
(2010)
Nature.
, vol.468
, Issue.7327
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
-
98
-
-
76149146414
-
Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature
-
Alkemade FE, van Vliet P, Henneman P, et al. Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature. Am J Pathol. 2010;176(2):542-8.
-
(2010)
Am J Pathol.
, vol.176
, Issue.2
, pp. 542-548
-
-
Alkemade, F.E.1
Van Vliet, P.2
Henneman, P.3
-
99
-
-
77955162230
-
Epigenetics in atherosclerosis and inflammation
-
Wierda RJ, Geutskens SB, Jukema JW, et al. Epigenetics in atherosclerosis and inflammation. J Cell Mol Med. 2010;14 (6A):1225-40.
-
(2010)
J Cell Mol Med.
, vol.14
, Issue.6 A
, pp. 1225-1240
-
-
Wierda, R.J.1
Geutskens, S.B.2
Jukema, J.W.3
-
100
-
-
52949118482
-
The multifaceted contributions of leukocyte subsets to atherosclerosis: Lessons from mouse models
-
Weber C, Zernecke A, Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol. 2008;8(10):802-15.
-
(2008)
Nat Rev Immunol.
, vol.8
, Issue.10
, pp. 802-815
-
-
Weber, C.1
Zernecke, A.2
Libby, P.3
|