메뉴 건너뛰기




Volumn 375, Issue 3, 2003, Pages 777-783

Interferon-γ regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways

Author keywords

Interferon ; Macrophage; Nucleoside transporter; Signal transduction

Indexed keywords

BIOSYNTHESIS; DNA; GENES; INTERFERONS; NITROGEN OXIDES; RNA;

EID: 10744230385     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030260     Document Type: Article
Times cited : (42)

References (55)
  • 1
    • 0030606020 scopus 로고    scopus 로고
    • Nucleoside and nucleobase transport systems of mammalian cells
    • Griffith, D. A. and Jarvis, S. M. (1996) Nucleoside and nucleobase transport systems of mammalian cells. Biochim. Biophys. Acta 1286, 153-181
    • (1996) Biochim. Biophys. Acta , vol.1286 , pp. 153-181
    • Griffith, D.A.1    Jarvis, S.M.2
  • 2
    • 0033136943 scopus 로고    scopus 로고
    • Nucleoside transporters: Molecular biology and implications for therapeutic development
    • Baldwin, S. A., Mackey, J. R., Cass, C. E. and Young, J. D. (1999) Nucleoside transporters: molecular biology and implications for therapeutic development. Mol. Med. Today 5, 216-224
    • (1999) Mol. Med. Today , vol.5 , pp. 216-224
    • Baldwin, S.A.1    Mackey, J.R.2    Cass, C.E.3    Young, J.D.4
  • 3
    • 0035042673 scopus 로고    scopus 로고
    • Recent advances in the molecular biology and physiology of nucleoside and nucleobase transporters
    • Pastor-Anglada, M. and Baldwin, S. A. (2001) Recent advances in the molecular biology and physiology of nucleoside and nucleobase transporters. Drug Dev. Res. 52, 431-437
    • (2001) Drug Dev. Res. , vol.52 , pp. 431-437
    • Pastor-Anglada, M.1    Baldwin, S.A.2
  • 4
    • 0034995844 scopus 로고    scopus 로고
    • The ENT family of eukaryote nucleoside and nucleobase transporters: Recent advances in the investigation of structure/function relationships and the identification of novel isoforms
    • Hyde, R. J., Cass, C. E., Young, J. D. and Baldwin, S. A. (2001) The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol. Membr. Biol. 18, 53-63
    • (2001) Mol. Membr. Biol. , vol.18 , pp. 53-63
    • Hyde, R.J.1    Cass, C.E.2    Young, J.D.3    Baldwin, S.A.4
  • 5
    • 0032192444 scopus 로고    scopus 로고
    • Transport and mode of action of nucleoside derivatives used in chemical and antiviral therapies
    • Pastor-Anglada, M., Felipe, A. and Casado, F. J. (1998) Transport and mode of action of nucleoside derivatives used in chemical and antiviral therapies. Trends Pharmacol. Sci. 19, 424-430
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 424-430
    • Pastor-Anglada, M.1    Felipe, A.2    Casado, F.J.3
  • 6
    • 0034666069 scopus 로고    scopus 로고
    • Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes
    • Lostao, M. P., Mata, J. F., Larrayoz, I. M., Inzillo, S. M., Casado, F. J. and Pastor-Anglada, M. (2000) Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes. FEBS Lett. 481, 137-140
    • (2000) FEBS Lett. , vol.481 , pp. 137-140
    • Lostao, M.P.1    Mata, J.F.2    Larrayoz, I.M.3    Inzillo, S.M.4    Casado, F.J.5    Pastor-Anglada, M.6
  • 8
    • 0035976921 scopus 로고    scopus 로고
    • Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs
    • Sundaram, M., Yao, S. Y. M., Ingram, J. C., Berry, Z. A., Abidi, F, Cass, C. E., Baldwin, S.A. and Young, J. D. (2001) Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs. J. Biol. Chem. 276, 45270-45275
    • (2001) J. Biol. Chem. , vol.276 , pp. 45270-45275
    • Sundaram, M.1    Yao, S.Y.M.2    Ingram, J.C.3    Berry, Z.A.4    Abidi, F.5    Cass, C.E.6    Baldwin, S.A.7    Young, J.D.8
  • 9
    • 0032570584 scopus 로고    scopus 로고
    • Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line
    • Crawford, C. R., Patel, D. H., Naeve, C. and Belt, J. A. (1998) Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line. J. Biol. Chem. 273, 5288-5293
    • (1998) J. Biol. Chem. , vol.273 , pp. 5288-5293
    • Crawford, C.R.1    Patel, D.H.2    Naeve, C.3    Belt, J.A.4
  • 10
    • 0028362987 scopus 로고
    • Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
    • Huang, Q. Q., Yao, S. Y., Ritzel, M. W., Paterson, A. R., Cass, C. E. and Young, J. D. (1994) Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J. Biol. Chem, 269, 17757-17760
    • (1994) J. Biol. Chem , vol.269 , pp. 17757-17760
    • Huang, Q.Q.1    Yao, S.Y.2    Ritzel, M.W.3    Paterson, A.R.4    Cass, C.E.5    Young, J.D.6
  • 15
    • 0008817735 scopus 로고    scopus 로고
    • Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells
    • Del Santo, B., Valdés, R., Mata, J., Felipe, A., Casado, F. J. and Pastor-Anglada, M. (1998) Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells. Hepatology 28, 1504-1511
    • (1998) Hepatology , vol.28 , pp. 1504-1511
    • Del Santo, B.1    Valdés, R.2    Mata, J.3    Felipe, A.4    Casado, F.J.5    Pastor-Anglada, M.6
  • 16
    • 0034948487 scopus 로고    scopus 로고
    • Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver
    • Del Santo, B., Tarafa, G., Felipe, A., Casado, F. J. and Pastor-Anglada, M. (2001) Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver. J. Hepatol. 34, 873-880
    • (2001) J. Hepatol. , vol.34 , pp. 873-880
    • Del Santo, B.1    Tarafa, G.2    Felipe, A.3    Casado, F.J.4    Pastor-Anglada, M.5
  • 18
    • 0033966609 scopus 로고    scopus 로고
    • CD3 activation induces concentrative nucleoside transport in human T lymphocytes
    • Kichenin, K., Pignede, G., Fudajed, F. and Seman, M. (2000) CD3 activation induces concentrative nucleoside transport in human T lymphocytes. Eur. J. Immunol. 30, 366-370
    • (2000) Eur. J. Immunol. , vol.30 , pp. 366-370
    • Kichenin, K.1    Pignede, G.2    Fudajed, F.3    Seman, M.4
  • 19
    • 0032500532 scopus 로고    scopus 로고
    • Regulation of nucleoside transport by lipopolysaccharide, phorbol esters, and tumor necrosis factor-α in human B-lymphocytes
    • Soler, C., Felipe, A., Casado, F. J., Celada, A. and Pastor-Anglada, M. (1998) Regulation of nucleoside transport by lipopolysaccharide, phorbol esters, and tumor necrosis factor-α in human B-lymphocytes. J. Biol. Chem. 273, 26939-26945
    • (1998) J. Biol. Chem. , vol.273 , pp. 26939-26945
    • Soler, C.1    Felipe, A.2    Casado, F.J.3    Celada, A.4    Pastor-Anglada, M.5
  • 20
    • 0036384221 scopus 로고    scopus 로고
    • Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs
    • Valdés, R., Casado, F. J. and Pastor-Anglada, M. (2002) Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs. Biochem. Biophys. Res. Commun. 296, 575-579
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 575-579
    • Valdés, R.1    Casado, F.J.2    Pastor-Anglada, M.3
  • 22
    • 0035839490 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced apoptosis of macrophages determines the up-regulation of concentrative nucleoside transporters Cnt1 and Cnt2 through tumor necrosis factor-α-dependent and -independent mechanisms
    • Soler, C., Valdés, R., García-Manteiga, J., Xaus, J., Comalada, M., Casado, J. J., Modolell, M., Nicholson, B., MacLeod, C., Felipe, A. et al. (2001) Lipopolysaccharide-induced apoptosis of macrophages determines the up-regulation of concentrative nucleoside transporters Cnt1 and Cnt2 through tumor necrosis factor-α-dependent and -independent mechanisms. J. Biol. Chem. 276, 30043-30049
    • (2001) J. Biol. Chem. , vol.276 , pp. 30043-30049
    • Soler, C.1    Valdés, R.2    García-Manteiga, J.3    Xaus, J.4    Comalada, M.5    Casado, J.J.6    Modolell, M.7    Nicholson, B.8    MacLeod, C.9    Felipe, A.10
  • 23
    • 0030889207 scopus 로고    scopus 로고
    • The IFN γ receptor: A paradigm for cytokine receptor signaling
    • Bach, E. A., Aguet, M. and Schreiber, R. D. (1997) The IFN γ receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol. 15, 563-591
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 25
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • Cambridge, Mass.
    • O'Shea, J. J., Massimo, G. and Schreiber, R. D. (2002) Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell (Cambridge, Mass.) 109, S121-S131
    • (2002) Cell , vol.109
    • O'Shea, J.J.1    Massimo, G.2    Schreiber, R.D.3
  • 29
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and -independent pathways in IFN-γ-dependent signaling
    • Ramana, C. V., Gil, M. P., Schreiber, R. D. and Stark, G. R. (2002) Stat1-dependent and -independent pathways in IFN-γ-dependent signaling. Trends Immunol. 23, 96-101
    • (2002) Trends Immunol. , vol.23 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 32
    • 13344282731 scopus 로고    scopus 로고
    • Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
    • Cambridge, Mass.
    • Meraz, M. A., White, J. M., Sheehan, K. C. F., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D. et al. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell (Cambridge, Mass.) 84, 431-442
    • (1996) Cell , vol.84 , pp. 431-442
    • Meraz, M.A.1    White, J.M.2    Sheehan, K.C.F.3    Bach, E.A.4    Rodig, S.J.5    Dighe, A.S.6    Kaplan, D.H.7    Riley, J.K.8    Greenlund, A.C.9    Campbell, D.10
  • 33
    • 0021183978 scopus 로고
    • Evidence for a γ-interferon receptor that regulates macrophage tumoricidal activity
    • Celada, A., Gray, P. W., Rinderknecht, E. and Schreiber, R. D. (1984) Evidence for a γ-interferon receptor that regulates macrophage tumoricidal activity. J. Exp. Med. 160, 55-74
    • (1984) J. Exp. Med. , vol.160 , pp. 55-74
    • Celada, A.1    Gray, P.W.2    Rinderknecht, E.3    Schreiber, R.D.4
  • 34
    • 0033214545 scopus 로고    scopus 로고
    • Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells
    • Munder, M., Eichmann, K., Moran, J. M., Centeno, F., Soler, G. and Modolell, M. (1999) Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. J. Immunol. 163, 3771-3777
    • (1999) J. Immunol. , vol.163 , pp. 3771-3777
    • Munder, M.1    Eichmann, K.2    Moran, J.M.3    Centeno, F.4    Soler, G.5    Modolell, M.6
  • 35
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Cambridge, Mass.
    • Durbin, J. E., Hackenmiller, R., Simon, M. C. and Levy, D. E. (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell (Cambridge, Mass.) 84, 443-450
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 38
    • 0033166302 scopus 로고    scopus 로고
    • Interferon γ induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
    • Xaus, J., Cardó, M., Valledor, A. F., Soler, C., Lloberas, J. and Celada, A. (1999) Interferon γ induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity 11, 103-113
    • (1999) Immunity , vol.11 , pp. 103-113
    • Xaus, J.1    Cardó, M.2    Valledor, A.F.3    Soler, C.4    Lloberas, J.5    Celada, A.6
  • 39
    • 0029923780 scopus 로고    scopus 로고
    • Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
    • Chin, Y. E., Kitagawa, M., Su, W. C., You, Z. H., Iwamoto, Y. and Fu, X. Y. (1996) Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272, 719-722
    • (1996) Science , vol.272 , pp. 719-722
    • Chin, Y.E.1    Kitagawa, M.2    Su, W.C.3    You, Z.H.4    Iwamoto, Y.5    Fu, X.Y.6
  • 40
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • Kumar, A., Commane, M., Flickinger, T. W., Horvath, C. M. and Stark, G. R. (1997) Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278, 1630-1632
    • (1997) Science , vol.278 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.W.3    Horvath, C.M.4    Stark, G.R.5
  • 41
    • 0034254726 scopus 로고    scopus 로고
    • How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
    • Chatterjee-Kishore, M., Wright, K. L., Ting, J. P.-Y. and Stark, G. R. (2000) How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. EMBO J. 19, 4111-4122
    • (2000) EMBO J. , vol.19 , pp. 4111-4122
    • Chatterjee-Kishore, M.1    Wright, K.L.2    Ting, J.P.-Y.3    Stark, G.R.4
  • 42
    • 0035067108 scopus 로고    scopus 로고
    • Requirement for STAT1 in LPS-induced gene expression in macrophages
    • Ohmori, Y. and Hamilton, T. A. (2001) Requirement for STAT1 in LPS-induced gene expression in macrophages. J. Leukoc. Biol. 69, 598-604
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 598-604
    • Ohmori, Y.1    Hamilton, T.A.2
  • 43
    • 0032521284 scopus 로고    scopus 로고
    • Induction of Jak/STAT signaling by activation of the type 1 TNF receptor
    • Guo, D., Dunbar, J. D., Yang, C. H., Pfeffer, L. M. and Donner, D. B. (1998) Induction of Jak/STAT signaling by activation of the type 1 TNF receptor. J. Immunol. 160, 2742-2750
    • (1998) J. Immunol. , vol.160 , pp. 2742-2750
    • Guo, D.1    Dunbar, J.D.2    Yang, C.H.3    Pfeffer, L.M.4    Donner, D.B.5
  • 44
    • 0034130327 scopus 로고    scopus 로고
    • Stat1 as a component of tumor necrosis factor-α receptor 1-TRADD signaling complex to inhibit NF-κB activation
    • Wang, Y., Wu, T. R., Cai, S., Welte, T. and Chin, Y. E. (2000) Stat1 as a component of tumor necrosis factor-α receptor 1-TRADD signaling complex to inhibit NF-κB activation. Mol. Cell. Biol. 20, 4505-4512
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4505-4512
    • Wang, Y.1    Wu, T.R.2    Cai, S.3    Welte, T.4    Chin, Y.E.5
  • 45
    • 0034649216 scopus 로고    scopus 로고
    • Genomic organization and expression of the mouse equilibrative, nitrobenzylthioinosine-sensitive nucleoside transporter 1 (ENT1) gene
    • Choi, D.-S., Handa, M., Young, H., Gordon, A. S., Diamond, I. and Messing, R. O. (2000) Genomic organization and expression of the mouse equilibrative, nitrobenzylthioinosine-sensitive nucleoside transporter 1 (ENT1) gene. Biochem. Biophys. Res. Commun. 277, 200-208
    • (2000) Biochem. Biophys. Res. Commun. , vol.277 , pp. 200-208
    • Choi, D.-S.1    Handa, M.2    Young, H.3    Gordon, A.S.4    Diamond, I.5    Messing, R.O.6
  • 46
    • 0037192761 scopus 로고    scopus 로고
    • A novel role of Sp1 and Sp3 in the interferon-γ-mediated suppression of macrophage lipoprotein lipase gene transcription
    • Hughes, T. R., Tengku-Muhammad, T. S., Irvine, S. A. and Ramji, D. P. (2002) A novel role of Sp1 and Sp3 in the interferon-γ-mediated suppression of macrophage lipoprotein lipase gene transcription. J. Biol. Chem. 277, 11097-11106
    • (2002) J. Biol. Chem. , vol.277 , pp. 11097-11106
    • Hughes, T.R.1    Tengku-Muhammad, T.S.2    Irvine, S.A.3    Ramji, D.P.4
  • 47
    • 0034725041 scopus 로고    scopus 로고
    • CCAAT/ enhancer-binding protein-β regulates interferon-induced transcription through a novel element
    • Roy, S. K., Wachira, S. J., Weihua, X., Hu, J. and Kalvakolanu, D. V. (2000) CCAAT/ enhancer-binding protein-β regulates interferon-induced transcription through a novel element. J. Biol. Chem. 275, 12626-12632
    • (2000) J. Biol. Chem. , vol.275 , pp. 12626-12632
    • Roy, S.K.1    Wachira, S.J.2    Weihua, X.3    Hu, J.4    Kalvakolanu, D.V.5
  • 49
    • 0027173063 scopus 로고
    • CSF-1 stimulates nucleoside transport in S1 macrophages
    • Meckling-Gill, K. A., Guilbert, L. and Cass, C. E. (1993) CSF-1 stimulates nucleoside transport in S1 macrophages. J. Cell. Physiol. 155, 530-538
    • (1993) J. Cell. Physiol. , vol.155 , pp. 530-538
    • Meckling-Gill, K.A.1    Guilbert, L.2    Cass, C.E.3
  • 51
    • 0028916297 scopus 로고
    • Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines
    • Modolell, M., Corraliza, I. M., Link, F., Soler, G. and Eichmann, K. (1995) Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines. Eur. J. Immunol. 25, 1101-1104
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1101-1104
    • Modolell, M.1    Corraliza, I.M.2    Link, F.3    Soler, G.4    Eichmann, K.5
  • 52
    • 0035844305 scopus 로고    scopus 로고
    • Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
    • Nicholson, B., Manner, K., Kleeman, J. and MacLeod, C. (2001) Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J. Biol. Chem. 276, 15881-15885
    • (2001) J. Biol. Chem. , vol.276 , pp. 15881-15885
    • Nicholson, B.1    Manner, K.2    Kleeman, J.3    MacLeod, C.4
  • 54
    • 0028658374 scopus 로고
    • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
    • Cambridge, Mass.
    • Mannick, J. B., Asano, K., Izumi, K., Kieff, E. and Stamler, J. S. (1994) Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell (Cambridge, Mass.) 79, 1137-1146
    • (1994) Cell , vol.79 , pp. 1137-1146
    • Mannick, J.B.1    Asano, K.2    Izumi, K.3    Kieff, E.4    Stamler, J.S.5
  • 55
    • 0037165658 scopus 로고    scopus 로고
    • PKC regulation of the human equilibrative nucleoside transporter, hENT1
    • Coe, I., Zhang, Y., Mckenzie, T. and Naydenova, Z. (2002) PKC regulation of the human equilibrative nucleoside transporter, hENT1. FEBS Lett. 517, 201-205
    • (2002) FEBS Lett. , vol.517 , pp. 201-205
    • Coe, I.1    Zhang, Y.2    Mckenzie, T.3    Naydenova, Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.