메뉴 건너뛰기




Volumn 112, Issue 8, 2003, Pages 1176-1185

Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; DIFFERENTIATION ANTIGEN; HIGH DENSITY LIPOPROTEIN; I KAPPA B; I KAPPA B KINASE; I KAPPA B KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; CHUK PROTEIN, MOUSE; IKBKB PROTEIN, MOUSE; IKBKE PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; PROTEIN SERINE THREONINE KINASE;

EID: 0346727295     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200318580     Document Type: Article
Times cited : (291)

References (33)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A.J. 2000. Atherosclerosis. Nature. 407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 2
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 3
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. 2002. Inflammation in atherosclerosis. Nature. 420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 4
    • 0034746311 scopus 로고    scopus 로고
    • NF-kappaB: Pivotal mediator or innocent bystander in acherogenesis?
    • Collins, T., and Cybulsky, M.I. 2001. NF-kappaB: pivotal mediator or innocent bystander in acherogenesis? J. Clin. Invest. 107:255-264.
    • (2001) J. Clin. Invest. , vol.107 , pp. 255-264
    • Collins, T.1    Cybulsky, M.I.2
  • 5
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor-kappa B is present in the athetosclerotic lesion
    • Brand, K., et al. 1996. Activated transcription factor nuclear factor-kappa B is present in the athetosclerotic lesion. J. Clin. Invest. 97:1715-1722.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1715-1722
    • Brand, K.1
  • 6
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • Karin, M., and Ben-Neriah, Y. 2000. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 18:621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 7
    • 0033537739 scopus 로고    scopus 로고
    • Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
    • Li, Q., Van Antwerp, D., Mercurio, F., Lee, K.F., and Verma, I.M. 1999. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science. 284:321-325.
    • (1999) Science , vol.284 , pp. 321-325
    • Li, Q.1    Van Antwerp, D.2    Mercurio, F.3    Lee, K.F.4    Verma, I.M.5
  • 8
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li, Z.W., et al. 1999. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J. Exp. Med. 189:1839-1845.
    • (1999) J. Exp. Med. , vol.189 , pp. 1839-1845
    • Li, Z.W.1
  • 9
    • 0037142027 scopus 로고    scopus 로고
    • TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
    • Pasparakis, M., et al. 2002. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature. 417:861-866.
    • (2002) Nature , vol.417 , pp. 861-866
    • Pasparakis, M.1
  • 10
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • Clausen, B.E., Burkhardt, C., Reith, W., Renkawitz, R., and Forster, I. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8:265-277.
    • (1999) Transgenic Res. , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 11
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S., et al. 1993. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92:883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1
  • 12
    • 0032977440 scopus 로고    scopus 로고
    • Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
    • de Winther, M.P., et al. 1999. Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice. Atherosclerosis. 144:315-321.
    • (1999) Atherosclerosis , vol.144 , pp. 315-321
    • De Winther, M.P.1
  • 13
    • 0033030088 scopus 로고    scopus 로고
    • Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: An immunohistochemical study
    • Gijbels, M.J., et al. 1999. Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: an immunohistochemical study. Atherosclerosis. 143:15-25.
    • (1999) Atherosclerosis , vol.143 , pp. 15-25
    • Gijbels, M.J.1
  • 14
    • 0031922432 scopus 로고    scopus 로고
    • RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis
    • Kockx, M.M., Muhring, J., Knaapen, M.W., and de Meyer, G.R. 1998. RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis. Am. J. Pathol. 152:885-888.
    • (1998) Am. J. Pathol. , vol.152 , pp. 885-888
    • Kockx, M.M.1    Muhring, J.2    Knaapen, M.W.3    De Meyer, G.R.4
  • 15
    • 0034018021 scopus 로고    scopus 로고
    • Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: Role of cell heterogeneity, microbial strain, and culture conditions in vitro
    • Peiser, L., Gough, P.J., Kodama, T., and Gordon, S. 2000. Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: role of cell heterogeneity, microbial strain, and culture conditions in vitro. Infect. Immun. 68:1953-1963.
    • (2000) Infect. Immun. , vol.68 , pp. 1953-1963
    • Peiser, L.1    Gough, P.J.2    Kodama, T.3    Gordon, S.4
  • 16
    • 0021044136 scopus 로고
    • Optimal conditions for proliferation of bone marrow-derived mouse macrophages in culture: The roles of CSF-1, serum, Ca2+, and adherence
    • Hume, D.A., and Gordon, S. 1983. Optimal conditions for proliferation of bone marrow-derived mouse macrophages in culture: the roles of CSF-1, serum, Ca2+, and adherence. J. Cell Physiol. 117:189-194.
    • (1983) J. Cell Physiol. , vol.117 , pp. 189-194
    • Hume, D.A.1    Gordon, S.2
  • 17
    • 0033638970 scopus 로고    scopus 로고
    • NEMO/IKK gamma-deficient mice model incontinentia pigmenti
    • Schmidt-Supprian, M., et al. 2000. NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol. Cell. 5:981-992.
    • (2000) Mol. Cell , vol.5 , pp. 981-992
    • Schmidt-Supprian, M.1
  • 18
    • 0029991139 scopus 로고    scopus 로고
    • Lipoprotein lipase stimulates the binding and uptake of moderately oxidized low-density lipoprotein by J774 macrophages
    • Hendriks, W.L., van der Boom, H., van Vark, L.C., and Havekes, L.M. 1996. Lipoprotein lipase stimulates the binding and uptake of moderately oxidized low-density lipoprotein by J774 macrophages. Biochem. J. 314:563-568.
    • (1996) Biochem. J. , vol.314 , pp. 563-568
    • Hendriks, W.L.1    Van Der Boom, H.2    Van Vark, L.C.3    Havekes, L.M.4
  • 19
    • 0023213632 scopus 로고
    • Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism
    • Steinbrecher, U.P., Witztum, J.L., Parthasarathy, S., and Steinberg, D. 1987. Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism. Arteriosclerosis. 7:135-143.
    • (1987) Arteriosclerosis , vol.7 , pp. 135-143
    • Steinbrecher, U.P.1    Witztum, J.L.2    Parthasarathy, S.3    Steinberg, D.4
  • 20
    • 0033592748 scopus 로고    scopus 로고
    • The toll-like receptor 2 is recruited to macrophage phagosomes mad discriminates between pathogens
    • Underhill, D.M., et al. 1999. The toll-like receptor 2 is recruited to macrophage phagosomes mad discriminates between pathogens. Nature. 401:811-815.
    • (1999) Nature , vol.401 , pp. 811-815
    • Underhill, D.M.1
  • 21
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
    • Beg, A.A., Sha, W.C., Bronson, R.T., Ghosh, S., and Baltimore, D. 1995. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 376:167-170.
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 22
    • 0033119952 scopus 로고    scopus 로고
    • Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
    • Tanaka, M., et al. 1999. Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. Immunity. 10:421-429.
    • (1999) Immunity , vol.10 , pp. 421-429
    • Tanaka, M.1
  • 23
    • 0028215636 scopus 로고
    • Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice
    • van Vlijmen, B.J., et al. 1994. Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice. J. Clin. Invest. 93:1403-1410.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1403-1410
    • Van Vlijmen, B.J.1
  • 24
    • 0037119628 scopus 로고    scopus 로고
    • IkappaB kinase signaling is essential for maintenance of mature B cells
    • Pasparakis, M., Schmidt-Supprian, M., and Rajewsky, K. 2002. IkappaB kinase signaling is essential for maintenance of mature B cells. J. Exp. Med. 196:743-752.
    • (2002) J. Exp. Med. , vol.196 , pp. 743-752
    • Pasparakis, M.1    Schmidt-Supprian, M.2    Rajewsky, K.3
  • 25
    • 0032991052 scopus 로고    scopus 로고
    • Detection of B cells and proinflammatory cytokines in atherosclerotic plaques of hypercholesterolaemic apolipoprotein E knockout mice
    • Zhou, X., and Hansson, G.K. 1999. Detection of B cells and proinflammatory cytokines in atherosclerotic plaques of hypercholesterolaemic apolipoprotein E knockout mice. Scand. J. Immunol. 50:25-30.
    • (1999) Scand. J. Immunol. , vol.50 , pp. 25-30
    • Zhou, X.1    Hansson, G.K.2
  • 26
    • 0037066041 scopus 로고    scopus 로고
    • Expressien of toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation
    • Edfeldt, K., Swedenborg, J., Hansson, G.K., and Yan, Z.Q. 2002. Expressien of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation. 105:1158-1161.
    • (2002) Circulation , vol.105 , pp. 1158-1161
    • Edfeldt, K.1    Swedenborg, J.2    Hansson, G.K.3    Yan, Z.Q.4
  • 27
    • 0035005368 scopus 로고    scopus 로고
    • Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice
    • Elhage, R., et al. 2001. Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice. Atherosclerosis. 156:315-320.
    • (2001) Atherosclerosis , vol.156 , pp. 315-320
    • Elhage, R.1
  • 28
    • 0037023783 scopus 로고    scopus 로고
    • Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice
    • Schreyer, S.A., Vick, C.M., and LeBoeuf, R.C. 2002. Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice. J. Biol. Chem. 277:12364-12368.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12364-12368
    • Schreyer, S.A.1    Vick, C.M.2    LeBoeuf, R.C.3
  • 29
    • 0029955427 scopus 로고    scopus 로고
    • Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55
    • Schreyer, S.A., Peschon, J.J., and LeBoeuf, R.C. 1996. Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55. J. Biol. Chem. 271:26174-26178.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26174-26178
    • Schreyer, S.A.1    Peschon, J.J.2    LeBoeuf, R.C.3
  • 30
    • 0033569130 scopus 로고    scopus 로고
    • Protective role of interleukin-10 in atherosclerosis
    • Mallat, Z., et al. 1999. Protective role of interleukin-10 in atherosclerosis. Circ. Res. 85:e17-e24.
    • (1999) Circ. Res. , vol.85
    • Mallat, Z.1
  • 31
    • 0036533577 scopus 로고    scopus 로고
    • Autocrine deactivation of macrophages in transgenic mice constitutively overexpressing IL-10 under control of the human CD68 promoter
    • Lang, R., Rutschman, R.L., Greaves, D.R., and Murray, P.J. 2002. Autocrine deactivation of macrophages in transgenic mice constitutively overexpressing IL-10 under control of the human CD68 promoter. J. Immunol. 168:3402-3411.
    • (2002) J. Immunol. , vol.168 , pp. 3402-3411
    • Lang, R.1    Rutschman, R.L.2    Greaves, D.R.3    Murray, P.J.4
  • 32
    • 0036127058 scopus 로고    scopus 로고
    • Autocrine and exocrine regulation of interleukin-10 production in THP-1 cells stimulated with Borrelia burgdorferi lipoproteins
    • Giambartolomei, G.H., Dennis, V.A., Lasater, B.L., Murthy, P.K., and Philipp, M.T. 2002. Autocrine and exocrine regulation of interleukin-10 production in THP-1 cells stimulated with Borrelia burgdorferi lipoproteins. Infect. Immun. 70:1881-1888.
    • (2002) Infect. Immun. , vol.70 , pp. 1881-1888
    • Giambartolomei, G.H.1    Dennis, V.A.2    Lasater, B.L.3    Murthy, P.K.4    Philipp, M.T.5
  • 33
    • 0035665020 scopus 로고    scopus 로고
    • Possible new role for NF-kappaB in the resolution of inflammation
    • Lawrence, T., Gilroy, D.W., Colville-Nash, P.R., and Willoughby, D.A. 2001. Possible new role for NF-kappaB in the resolution of inflammation. Nat. Med. 7:1291-1297.
    • (2001) Nat. Med. , vol.7 , pp. 1291-1297
    • Lawrence, T.1    Gilroy, D.W.2    Colville-Nash, P.R.3    Willoughby, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.