Coordinated activation of Notch, Wnt, and transforming growth factor-β signaling pathways in bone morphogenic protein 2-induced osteogenesis: Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

Journal of Biological Chemistry

Volumn 279, Issue 36, 2004, Pages 37704-37715

  Zamurovic, Natasa ^a   Cappellen, David ^a   Rohner, Daisy ^a   Susa, Mira ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MICROARRAYS; OSTEOBLAST DIFFERENTIATION;

BONE; GENES; TARGETS;

BIOCHEMISTRY;

BONE MORPHOGENETIC PROTEIN 2; GENE PRODUCT; GROWTH FACTOR; HEY1 PROTEIN; NOTCH RECEPTOR; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; CYTOCHEMISTRY; DNA MICROARRAY; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BONE MORPHOGENETIC PROTEINS; CALCIFICATION, PHYSIOLOGIC; CELL CYCLE PROTEINS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA PRIMERS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOGENESIS; PROTO-ONCOGENE PROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

ANIMALIA; MURINAE;

EID: 4444246433     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403813200     Document Type: Article

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