An Overview of Lactic Acid Bacteria Applications for Healthful Soy Foods Development

Biotechnology of Lactic Acid Bacteria: Novel Applications

Volumn , Issue , 2010, Pages 289-300

  Savoy de Giori, Graciela ^a,b   Aguirre, Laura ^a,b   Marazza, José ^a   Garro, Marisa S ^a  

^a CENTRO DE REFERENCIA PARA LACTOBACILOS CERELA CONICET   (Argentina)

^b UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

Author keywords

An Overview of Lactic Acid bacteria applications for Healthful Soy Foods Development; Engineered LAB have been constructed to degrade GOS; Isoflavones Transformation by LAB; Several LAB are known to produce Gal; Soy Carbohydrates Metabolism by LAB; Soybean Nutritional Components; Structural gene from Lact. plantarum ATCC

Indexed keywords

EID: 84860994458     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780813820866.ch16     Document Type: Chapter

References (105)

1. Aguirre, L., Garro, M., and Savoy de Giori, G. (2008) Enzymatic hydrolysis of soybean protein using lactic acid bacteria. Food Chem 111, 976-982.
2. Angeles, A.G., and Marth, E.H. (1971) Growth and activity of lactic acid bacteria in soymilk. I: Growth and acid production. J Milk Food Technol 34, 30-36.
3. Beardslee, T.A., Zeece, M.G., Sarath, G., and Markwell, J.P. (2000) Soybean glycinin G1 acidic chain shares IgE epitopes with peanut allergen Ara h 3. Int Arch Allergy Immunol 123, 299-307.
4. Boucher, I., Vadeboncoeur, C., and Moineau, S. (2003) Characterization of genes involved in the metabolism of alpha-galactosides by Lactococcus raffinolactis. Appl Environ Microbiol 69, 4049-4056.
5. Cadenas, E., and Parker, L. (2001) Handbook of Antioxidants. 2nd ed. New York: Marcel Dekker.
6. Carrera-Silva, A., Silvestroni, A., LeBlanc, J.G., Piard, J.C., Savoy de Giori, G., and Sesma, F. (2006) A thermostable alpha-galactosidase from Lactobacillus fermentum CRL 722: Genetic characterization and main properties. Curr Microbiol 53, 374-378.
7. Chang, Y.C., and Nair, M.G. (1995) Metabolism of daidzein and genistein by intestinal bacteria. J Nat Prod 58, 1892-1896.
8. Chen, H.M., Muramoto, K., Yamauchi, F., Fujimoto, K., and Nokihara, K. (1998) Antioxidative properties of histidine-containing peptides designed from peptide fragments found in the digests of a soybean protein. J Agric Food Chem 46, 49-53.
9. Chen, J., Okada, T., Muramoto, K., Suetsuna, K., and Yang, S. (2003) Identification of angiotensin I-converting enzyme inhibitory peptides derived from the peptic digest of soybean protein. J Food Biochem 26, 543-554.
10. Chen, J.R., Yang, S.C., Suetsuna, K., and Chao, J.C.J. (2004) Soybean protein-derived hydrolysate affects blood pressure in spontaneously hypertensive rats. J Food Biochem 28, 61-73.
11. Chun, J., Kim, J.S., and Kim, J.H. (2008) Enrichment of isoflavone aglycones in soymilk by fermentation with single and mixed cultures of Streptococcus infantarius 12 and Weissella sp. 4. Food Chem 109, 278-284.
12. Codina, R., Ardusso, L., Lockey, R.F., Crisci, C.D., Jaen, C., and Bertoya, N.H. (2002) Identification of the soybean hull allergens involved in sensitization to soybean dust in a rural population from Argentina and N-terminal sequence of a major 50 kD allergen. Clin Exp Allergy 32, 1059-1063.
13. Connes, C., Silvestroni, A., LeBlanc, J.G., Juillard, V., Savoy de Giori, G., Sesma, F., and Piard, J.C. (2004) Towards probiotic lactic acid bacteria strains to remove raffinose-type sugars present in soy derived products. Lait 84, 207-214.
14. Coward, L., Barnes, N.C., Setchell, K.D.R., and Barnes, S. (1993) Genistein, daidzein and theirâ-glycoside conjugates: Antitumor isoflavones in soybean foods from American and Asian diets. J Agric Food Chem 41, 1961-1967.
15. Coward, L., Smith, M., Kirk, M., and Barnes, S. (1998) Chemical modification of isoflavones in soyfoods during cooking and processing. A m J Clin Nutr 68, 1486S-1491S.
16. Cruz, R., Bastistela, J.C., and Wosiacki, G. (1981) Microbialá-galactosidase for soybean processing. J Food Sci 46, 1196-1200.
17. De Boever, P., Wouters, R., and Verstraete, W. (2001) Combined used of Lactobacillus reuteri and soygerm powder as food supplement. L ett Appl Microbiol 33, 420-424.
18. Donkor, O.N., Henriksson, A., Vasiljevic, T., and Shah, N.P. (2005) Probiotic strains as starter cultures improve angiotensin-converting enzyme inhibitory activity in soy yogurt. J Food Sci 70, M375-M381.
19. Frias, J., Soo Song, Y., Martínez-Villaluenga, C., González de Mejia, E., and Vidal-Valverde, C. (2008) Immunoreactivity and amino acid content of fermented soybean products. J Agric Food Chem 56, 99-105.
20. Ganiats, T.G., Norcross, W.A., Halverson, A.L., Burford, P.A., and Palinkas, L.A. (1994) Does Beano prevent gas? A double-blind crossover study of oral alpha-galactosidase to treat dietary oligosaccharide intolerance. J Fam Pract 39, 441-445.
21. Garro, M.S., de Valdez, G.F., Oliver, G., and Savoy de Giori, G. (1996) Purification ofá-galactosidase from Lactobacillus fermentum. J Biotechnol 45, 103-109.
22. Garro, M.S., De Valdez, G.F., and Savoy de Giori, G. (2004) Temperature effect on the biological activity of Bifidobacterium longum CRL 849 and Lactobacillus fermentum CRL 251 in pure and mixed cultures grown in soymilk. Food Microbiol 21, 511-518.
23. Gibbs, B.F., Zougman, A., Masse, R., and Mulligan, C. (2004) Production and characterization of bioactive peptides from soy hydrolyzes and soy-fermented foods. Food Res Int 37, 123-131.
24. González de Mejia, E., and de Lumen, B.O. (2006) Soybean bioactive peptides: A new horizon in preventing chronic diseases. Sex Reprod Menopause 4, 91-95.
25. González, R., Polo, F., Zapatero, L., Caravaca, F., and Carreira, J. (1992) Purification and characterization of major inhalant allergens from soybean hulls. Clin Exp Allergy 22, 748-755.
26. Gopal, P.K., Sullivan, P.A., and Smart, J.B. (2001) Utilization of galacto-oligosaccahrides as selective substrates for growth by lactic aid bacteria including Bifidobacterium lactis DR10 and Lactobacillus rhamnosus DR20. Int Dairy J 11, 19-25.
27. Gote, M., Umalkar, H., Khan, I., and Khire, J. (2004) Thermostableá-galactosidase from Bacillus stearothermophilus (NCIM 5146) and its application in the removal of flatulence causing factors from soymilk. Process Biochem 39, 1723-1729.
28. Gouda, K.G.M., Gowda, L.R., Appu Rao, A.G., and Prakash, V. (2006) Angiotensin I-converting enzyme inhibitory peptide derived from glycinin, the 11s globulin of soybean (Glycine max). J Agric Food Chem 54, 4568-4573.
29. Helm, R.M., Cockrell, G., Connaughton, C., Sampson, H.A., Bannon, G.A., Beilinson, V., Livingstone, D., Nielsen, N.C., and Burks, A.W. (2000a) A soybean G2 glycinin allergen 1. Identification and characterization. Int Arch Allergy Immunol 123, 205-212.
30. Helm, R.M., Cockrell, G., Connaughton, C., Sampson, H.A., Bannon, G.A., Beilinson, V., Nielsen, N.C., and Burks, A.W.
31. Helm R.M., Cockrell, G., Connaughton, C., Sampson, H.A., Bannon, G.A., Beilinson, V., Nielsen, N.C., and Burks, A.W. (2000b) A soybean G2 glycinin allergen 2. Epitope mapping and three-dimensional modeling. Int Arch Allergy Immunol 123, 213-219.
32. Hendrich, S., Wang, G.J., and Lin, H.K. (1999) Isoflavone metabolism and bioavailability. In Antioxidant Status, Diet, Nutrition and Health, ed. A.M. Papas, 211-230. Boca Raton FL: CRC Press.
33. Hiemori, M., Bando, N., Ogawa, T., Shimada, H., Tsuji, H., Yamanishi, R., and Terao, J. (2000) Occurrence of IgE antibody-recognizing N linked glycan moiety of a soybean allergen, Gly m Bd 28 K. Int Arch Allergy Immunol 144, 238-245.
34. Hiemori, M., Ito, H., Kimoto, M., Yamashita, H., Nishizawa, K., Maruyama, N., Utsumi, S., and Tsuji, H. (2004) Identification of the 23-kDa peptide derived from the precursor of Gly m Bd 28K, a major soybean allergen, as a new allergen. Biochim Biophys Acta 1675, 174-183.
35. Hou, H.J., and Chang, K.C. (2004a) Structural characteristics of purified glycinin from soybeans stored under various conditions. J Agric Food Chem 52, 3792-3800.
36. Hou, H.J., and Chang, K.C. (2004b) Structural characteristics of purifiedâ-conglycinin from soybeans stored under four conditions. J Agric Food Chem 52, 7931-7937.
37. Hung, Y.H., Huang, H.Y., and Chou, C.C. (2007) Mutagenic and antimutagenic effects of methanol extracts of unfermented and fermented black soybeans. Int J Food Microbiol 118, 62-68.
38. Ibrahim, S.S., Habiba, R.A., Shatta, A.A., and Embaby, H.E. (2002) Effect of soaking, germination, cooking and fermentation on antinutritional factors in cowpeas. Nahrung 46, 92-95.
39. Kao, T.H., Lu, Y.F., Hsieh, H.C., and Chen, B.H. (2004) Stability of isoflavone glucosides during processing of soymilk and tofu. Food Res Int 37, 891-900.
40. Kim, S.E., Kim, H.H., Kim, J.Y., Kang, Y.I., Woo, H.J., and Lee, H.J. (2000) Anticancer activity of hydrophobic peptides from soy proteins. BioFactors 12, 151-155.
41. Kim, J.H., Park, J.Y., Jeong, S.J., Chun, J.Y., Lee, J.H., Chung, D.K., and Kim, J.H. (2005) Characterization of theá- galactosidase gene from Leuconostoc mesenteroides SY1. J Microbiol Biotechnol 14, 509-512.
42. Kitts, D.D., and Weiler, K. (2003) Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery. Curr Pharm Des 9, 1309-1323.
43. Kobayashi, M. (2005) Immunological functions of soy sauce: Hypoallergenicity and antiallergenic activity of soy sauce. J Biosci Bioeng 100, 144-151.
44. Kodera, T., and Nio, N. (2006) Identification of an angiotensin I-converting enzyme inhibitory peptides from protein hydrolysates by a soybean protease and the antihypertensive effects of hydrolysates in spontaneously hypertensive model rats. J Food Sci 71, C164-C173.
45. Korhonen, H., and Pihlanto, A. (2003) Food-derived bioactive peptides. Opportunities for designing future foods. Curr Pharm Design 9, 1297-1308.
46. Kotwal, S.M., Gote, M.M., Sainkar, S.R., Khan, M.I., and Khire, J.M. (1998) Production ofá-galactosidase by thermophilic fungus Humicola sp. in solid-state fermentation and its application in soymilk hydrolysis. Process Biochem 33, 337-343.
47. Kuba, M., Tanaka, K., Tawata, S., Takeda, Y., and Yasuda, M. (2003) Angiotensin I-converting enzyme inhibitory peptides isolated from tofuyo fermented soybean food. Biosci Biotechnol Biochem 67, 1278-1283.
48. LeBlanc, J.G., Garro, M.S., Silvestroni, A., Connes, C., Piard, J.C., Sesma, F., and Savoy de Giori, G. (2004) Reduction of alpha-galactooligosaccharides in soyamilk by Lactobacillus fermentum CRL 722: In vitro and in vivo evaluation of fermented soyamilk. J Appl Microbiol 97, 876-881.
49. LeBlanc, J.G., Piard, J.C., Sesma, F., and Savoy de Giori, G. (2005) Lactobacillus fermentum CRL 722 is able to deliver active alpha-galactosidase activity in the small intestine of rats. FEMS Microbiol Lett 248, 177-182.
50. LeBlanc, J., Clier, F., Bensaada, M., Savoy de Giori, G., Guerekobaya, T., Sesma, F., Juillard, V., Rabot, S., and Piard, J.C. (2008) Ability of Lactobacillus fermentum to overcome host alpha-galactosidase deficiency, as evidenced by reduction of hydrogen excretion in rats consuming soya alpha-galacto-oligosaccharides. BMC Microbiol 29, 22-31.
51. Liener, I. (1994) Implications of antinutritional components in soybean foods. Crit Rev Food Sci Nutr 34, 31-67.
52. Lori, C., Michelle, S., Marion, K., and Stephen, B. (1998) Chemical modification of isoflavones in soyfoods during cooking and processing. Am J Clin Nutr 68, 1486S-1491S.
53. Lovati, M.R., Manzoni, C., Gianazza, E., Arnoldi, A., Kurowska, E., and Carroll, K.K. (2000) Soy protein peptides regulate cholesterol homeostasis in Hep G2 cells. J Nutr 130, 2543-2549.
54. Mahungu, S.M., Diaz-Mercado, S., Li, J., Schwenk, M., Singeltary, K., and Faller, J. (1999) Stability of isoflavones during extrusion processing of corn/soy mixture. J Agric Food Chem 47, 279-284.
55. Manzoni, C., Duranti, M., Eberini, I., Scharnag, H., Marz, W., and Castiglioni, S. (2003) Subcellular localization of soybean 7S globulin in HepG2 cells and LDL receptor up-regulation by its alphaV constituent subunit. J Nutr 133, 2149-2155.
56. Marazza, J., Garro, M., and Savoy de Giori, G. (2009) Aglycone production by Lactobacillus rhamnosus CRL 981 during soymilk fermentation. Food Microbiol 26, 333-339.
57. Middleton, E., Kandaswamy, C., and Theoharides, T.C. (2000) The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer. Pharmacol Rev 52, 673-751.
58. Mittag, D., Vieths, S., Vogel, L., Becker, W-M., Rihs, H-P., Helbling, A., Wüthrich, B., and Ballmer-Weber, B.K. (2004) Soybean allergy in patients allergic to birch pollen: Clinical investigation and molecular characterization of allergens. J Allergy Clin Immunol 113, 148-154.
59. Murti, T.W., Bouillanne, C., Landon, M., and Desmazeaud, M.J. (1993) Bacterial growth and volatile compounds in yoghurt-type products from soymilk containing Bifidobacterium ssp. J Food Sci 58, 153-157.
60. Ogawa, T. (2006) Soy allergy. In Soy in Health and Disease Prevention, ed. M. Sugano, 123-138. Boca Raton FL: CRC Press Taylor & Francis Group.
61. Boca Raton, FL: CRC Press Taylor & Francis Group. Ogawa, T., Bando, N., Tsuji, H., Okajima, H., Nishikawa, K., and Sasaoka, K. (1991) Investigation of the IgE-binding proteins in soybeans by immunoblotting with the sera of soybean-sensitive patients with atopic dermatitis. J Nutr Sci Vitaminol 37, 555-565.
62. Otieno, D.O., and Shah, P. (2007) A comparison of changes in the transformation of isoflavones in soymilk using varying concentrations of exogenous and probiotic-derived endogenous b-glucosidases. J Appl Microbiol 103, 601-612.
63. Otieno, D.O., Ashton, J.F., and Shah, N.P. (2006) Evaluation of enzymic potential for biotransformation of isoflavone phytoestrogen in soymilk by Bifidobacterium animalis, Lactobacillus acidophilus and Lactobacillus casei. Food Res Int 39, 394-407.
64. Park, Y.K., Aguiar, C.L., Alencar, S.M., Mascrenhas, H.A.A., and Scamparini, A.R.P. (2002) Conversion of malonyl ß-glucoside isoflavones into glycoside isoflavones found in some cultivars of Brazilian soybeans. Cienc Tecnol Aliment 22, 130-135.
65. Peña-Ramos, E.A., and Xiong, Y.L. (2002) Antioxidant activity of soy protein hydrolysates in a liposomal system. J Food Sci 67, 2952-2956.
66. Rackis, J.J. (1981) Flatulence caused by soya and its control through processing. J Am Oil Chem Soc 58, 503-510.
67. Rehms, H., and Barz, W. (1995) Degradation of stachyose, raffinose, melibiose and sucrose by different tempe-producing Rhizopus fungi. Appl Microbiol Biotechnol 44, 47-52.
68. Rihs, H.P., Chen, Z., and Rueff, F. (1999) IgE binding of the recombinant allergen soybean profilin (rGly m 3) is mediated by conformational epitopes. J Allergy Clin Immunol 104, 1293-1301.
69. Rodrigo, M.J., Morell, F., and Helm, R.M. (1990) Identification and partial characterization of the soybean-dust allergen involved in the Barcelona asthma epidemic. J Allergy Clin Immunol 85, 778-784.
70. Saito, K., Jin, D.H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T., and Nokihara, K. (2003) Antioxidative properties of tripeptide libraries prepared by the combinatorial chemistry. J Agric Food Chem 51, 3668-3674.
71. Schuler, R., Mudgett, R., and Mahoney, R.R. (1985) Kinetic properties ofá-D-galactosidase from Lactobacillus fermenti. Enzyme Microb Technol 7, 207-211.
72. Setchell, K.D.R. (2000) Absorption and metabolism of soy isoflavones from food to dietary supplements and adults to infants. J Nutr 130, 654S-655S.
73. Shelef, L.A., Bahnmiller, K.R., Zemel, M.B., and Monte, L.M. (1998) Fermentation of soymilk with commercial freeze-dried starter lactic cultures. J Food Process Preserv 12, 187-195.
74. Shimoni, E. (2004) Stability and shelf life of bioactive compounds during food processing and storage: Soy isoflavones. J Food Sci 69, 160-166.
75. Shin, Z.I., Yu, R., Park, S.A., Chung, D.K., Ahn, C.W., Nam, H.S., Kim, K.S., and Lee, H.J. (2001) His-His-Leu, an angiotensin I converting enzyme inhibitory peptide derived from Korean soybean paste, exerts antihypertensive activity in vivo. J Agric Food Chem 49, 3004-3009.
76. Silvestroni, A., Connes, C., Sesma, F., Savoy de Giori, G., and Piard, J.C. (2002) Characterization of the mel A locus for alpha-galactosidase in Lactobacillus plantarum. Appl Environ Microbiol 68, 5464-5471.
77. Slominski, B.A. (1994) Hydrolysis of galactooligosaccharides by commercial preparations ofá-galactosidase and a fructofuranosidase: Potential for use as dietary additives. J Sci Food Agric 65, 323-330.
78. Song, T., Barua, K., Buseman, G., and Murphy, P.A. (1998) Soy isoflavone analysis: Quality control and a new internal standard. Am J Clin Nutr 68, 1474S-1479S.
79. Sripuan, T., Aoki, K., Yamamoto, K., Tongkao, D., and Kumagai, H. (2003) Purification and characterization of thermostableá-galactosidase from Ganoderma lucidum. Biosci Biotechnol Biochem 67, 1485-1491.
80. Steggerda, F.R., Richards, E.A., and Rackis, J.J. (1996) Effects of various soybean products on flatulence in the adult man. Proc Soc Exp Biol Med 121, 1235-1239.
81. Thomas, K., Herouet-Guicheney, C., Ladics, G., Bannon, G., Cockburn, A., Crevel, R., Fitzpatrick, J., Mills, C., Privalle, L., and Vieths, S. (2007) Evaluating the effect of food processing on the potential human allergenicity of novel proteins: International workshop report. Food Chem Toxicol 45, 1116-1122.
82. Torres, N., Torre-Villalvazo, I., and Tovar, A.R. (2006) Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders. J Nutr Biochem 17, 365-373.
83. Tsai, J.S., Lin, Y.S., Pan, B.S., and Chen, T.J. (2006) Antihypertensive peptides and ã-aminobutyric acid from prozyme 6 facilitated lactic acid bacteria fermentation of soymilk. Process Biochem 41, 1282-1288.
84. Tsangalis, D., Wilcox, G., Shah, N.P., and Stojanovska, L. (2005) Bioavailability of isoflavone phytoestrogens in postmenopausal women consuming soya milk fermented with probiotic bifidobacteria. Br J Nutr 93, 867-877.
85. Tsuji, H., Bando, N., Hiemori, M., Yamanishi, R., Kimoto, M., Nishikawa, K., and Ogawa, T. (1997) Purification of characterization of soybean allergen Gly m Bd 28 K. Biosci Biotech Biochem 61, 942-947.
86. Tsuji, H., Hiemori, M., Kimoto, M., Yamashita, H., Kobatake, R., Adachi, M., Fukuda, T., Bando, N., Okita, M., and Utsumi, S. (2001) Cloning of cDNA encoding a soybean allergen, Gly m Bd 28 K. Biochim Biophys Acta 1518, 178-182.
87. Tzortzis, G., Goulas, A.K., Baillon, M.L.A., Gibson, G.R., and Rastall, R.A. (2004) In vitro evaluation of the fermentation properties of galactooligosaccharides synthesized byá- galactosidase from Lactobacillus reuteri. Appl Microbiol Biotechnol 64, 106-111.
88. Ungar, Y., Osundahunsi, O.F., and Shimoni, E. (2003) Thermal stability of genistein and daidzein and its effect on their antioxidant activity. J Agric Food Chem 51, 4394-4399.
89. U.S. Department of Agriculture, Agricultural Research Service. (2002) USDA-Iowa State University Database on the isoflavone content of foods, release 1.3-2002. Nutrient Data Laboratory. http://www.nal.usda.gov/fnic/foodcomp/Data/isoflav/isoflav.html. (accessed October 25, 2004).
90. Viana, P.A., De Rezende, S., Marques, V., Trevizano, L.M., Passos, F., Oliveira, M., Bemquerer, M., Oliveira, J., and Guimar ães, V. (2006) Extracellulará-galactosidase from Debaryomyces hansenii UFV-1 and its use in the hydrolysis of raffinose oligosaccharides. J Agric Food Chem 54, 2385-2391.
91. Wang, H.J., and Murphy, P.A. (1994) Isoflavone content in commercial soybean foods. J Agric Food Chem 42, 1666-1673.
92. Wang, G., Kuan, S.S., Francis, O.J., Ware, G.M., and Carman, A.S. (1990) A simplified HPLC method for the determination of phytoestrogens in soybean and its processed products. J Agric Food Chem 38, 185-190.
93. Wang, Y.C., Yu, R.C., and Chou, C.C. (2002) Growth and survival of bifidobacteria and lactic acid bacteria during the fermentation and storage of cultured soymilk drinks. Food Microbiol 19, 501-508.
94. Wang, Y.C., Yu, R.C., and Chou, C.C. (2006) Antioxidative activities of soymilk fermented with lactic acid bacteria and bifidobacteria. Food Microbiol 23, 128-135.
95. Wang, Y.C., Yu, R.C., Yang, H.Y., and Chou, C.C. (2003) Sugar and acid content in soymilk fermented with lactic acid bacteria alone or simultaneously with bifidobacteria. Food Microbiol 20, 333-338.
96. Wang, W., and Gonzalez de Mejia, E. (2005) A new frontier in soy bioactive peptides that may prevent age-related chronic diseases. Compr Rev Food Sci Food Safety 4, 63-78.
97. Wei, Q.K., Chen, T.R., and Chen, J.T. (2007) Using of Lactobacillus and Bifidobacterium to product the isoflavone aglycones in fermented soymilk. Int J Food Microbiol 117, 120-124.
98. Wilson, S., Blaschek, K., and González de Mejia, E. (2005) Allergenic proteins in soybean: Processing and reduction of P34 allergenicity. Nutr Rev 63, 47-58.
99. Wu, J., and Ding, X. (2001) Enzyme inhibitory peptides derived from soy protein on spontaneously hypertensive rats. J Agric Food Chem 49, 501-506.
100. Xiang, P., Beardslee, T.A., Zeece, M.G., Markwell, J., and Sarath, G. (2002) Identification and analysis of a conserved immunoglobulin E binding epitope in soybean G1a and G2a and peanut Ara h 3 glycinins. Arch Biochem Biophys 408, 51-57.
101. Xiang, P., Haas, E.J., Zeece, M.G., Markwell, J., and Sarath, G. (2004) C-Terminal 23 kDa polypeptide of soybean Gly m Bd 28 K is a potential allergen. Planta 220, 56-63.
102. Xiang, P., Baird, L.M., Jung, R., Zeece, M.G., Markwell, J., and Sarath, G. (2008) P39, a novel soybean protein allergen, belongs to a plant-specific protein family and is present in protein storage vacuoles. J Agric Food Chem 56, 2266-2272.
103. Yoon, M.Y., and Hwang, H.J. (2008) Reduction of soybean oligosaccharides and properties of a-D-galactosidase from Lactobacillus curvatus R08 and Leuconostoc mesenteriodes JK55. Food Microbiol 25, 815-823.
104. Yoshikawa, M., Fujita, H., Matoba, N., Takenaka, Y., Yamamoto, T., Yamauchi, R., Tsuruki, H., and Takahata, K. (2000) Bioactive peptides derived from food proteins preventing lifestyle-related diseases. Biofactors 12, 143-146.
105. Zhong, F., Zhang, X., Ma, J., and Shoemaker, C.F. (2007) Fractionation and identification of a novel hypocholesterolemic peptide derived from soy protein Alcalase hydrolysates. Food Res Int 40, 756-762.