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Volumn 53, Issue 3, 2012, Pages 1362-1371

Expression and role of p53 in the retina

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P21; PROTEIN P53; PROTEIN P63; PROTEIN P73; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR YY1; RETINOBLASTOMA PROTEIN;

EID: 84860575052     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8909     Document Type: Article
Times cited : (35)

References (147)
  • 1
    • 0018616778 scopus 로고
    • The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen
    • Linzer DI, Maltzman W, Levine AJ. The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen. Virology. 1979;98(2):308-318.
    • (1979) Virology , vol.98 , Issue.2 , pp. 308-318
    • Linzer, D.I.1    Maltzman, W.2    Levine, A.J.3
  • 2
    • 0021692341 scopus 로고
    • Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences
    • Wolf D, Rotter V. Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences. Mol Cell Biol. 1984;4(7):1402-1410.
    • (1984) Mol Cell Biol , vol.4 , Issue.7 , pp. 1402-1410
    • Wolf, D.1    Rotter, V.2
  • 3
    • 0023813658 scopus 로고
    • Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus
    • Ben DY, Prideaux VR, Chow V, Benchimol S, Bernstein A. Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus. Oncogene. 1988;3(2):179-185.
    • (1988) Oncogene , vol.3 , Issue.2 , pp. 179-185
    • Ben, D.Y.1    Prideaux, V.R.2    Chow, V.3    Benchimol, S.4    Bernstein, A.5
  • 4
    • 0021835959 scopus 로고
    • Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus
    • Mowat M, Cheng A, Kimura N, Bernstein A, Benchimol S. Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus. Nature. 1985;314(6012):633-636.
    • (1985) Nature , vol.314 , Issue.6012 , pp. 633-636
    • Mowat, M.1    Cheng, A.2    Kimura, N.3    Bernstein, A.4    Benchimol, S.5
  • 5
    • 0001606206 scopus 로고
    • Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells
    • Wolf D, Rotter V. Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci U S A. 1985;82(3):790-794.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , Issue.3 , pp. 790-794
    • Wolf, D.1    Rotter, V.2
  • 6
    • 0023764396 scopus 로고
    • Meth A fibrosarcoma cells express two transforming mutant p53 species
    • Eliyahu D, Goldfinger N, Pinhasi-Kimhi O, et al. Meth A fibrosarcoma cells express two transforming mutant p53 species. Oncogene. 1988;3(3):313-321.
    • (1988) Oncogene , vol.3 , Issue.3 , pp. 313-321
    • Eliyahu, D.1    Goldfinger, N.2    Pinhasi-Kimhi, O.3
  • 7
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered halflife
    • Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered halflife. Mol Cell Biol. 1988;8(2):531-539.
    • (1988) Mol Cell Biol , vol.8 , Issue.2 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine, A.J.6
  • 9
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay CA, Hinds PW, Levine AJ. The p53 proto-oncogene can act as a suppressor of transformation. Cell. 1989;57(7):1083-1093.
    • (1989) Cell , vol.57 , Issue.7 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 10
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz D, Halevy O, Oren M. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell. 1990;62(4):671-680.
    • (1990) Cell , vol.62 , Issue.4 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 11
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower LA, Harvey M, Slagle BL, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature. 1992;356(6366):215-221.
    • (1992) Nature , vol.356 , Issue.6366 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3
  • 12
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science. 1990;250(4985):1233-1238.
    • (1990) Science , vol.250 , Issue.4985 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3
  • 13
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature. 1990;348(6303):747-749.
    • (1990) Nature , vol.348 , Issue.6303 , pp. 747-749
    • Srivastava, S.1    Zou, Z.Q.2    Pirollo, K.3    Blattner, W.4    Chang, E.H.5
  • 14
    • 0034003005 scopus 로고    scopus 로고
    • Stress signals utilize multiple pathways to stabilize p53
    • Ashcroft M, Taya Y, Vousden KH. Stress signals utilize multiple pathways to stabilize p53. Mol Cell Biol. 2000;20(9):3224-3233.
    • (2000) Mol Cell Biol , vol.20 , Issue.9 , pp. 3224-3233
    • Ashcroft, M.1    Taya, Y.2    Vousden, K.H.3
  • 15
    • 0034823780 scopus 로고    scopus 로고
    • Regulation of p53 localization
    • Liang SH, Clarke MF. Regulation of p53 localization. Eur J Biochem. 2001;268(10):2779-2783.
    • (2001) Eur J Biochem , vol.268 , Issue.10 , pp. 2779-2783
    • Liang, S.H.1    Clarke, M.F.2
  • 16
    • 0033027346 scopus 로고    scopus 로고
    • Covalent and noncovalent modifiers of the p53 protein
    • Jayaraman L, Prives C. Covalent and noncovalent modifiers of the p53 protein. Cell Mol Life Sci. 1999;55(1):76-87.
    • (1999) Cell Mol Life Sci , vol.55 , Issue.1 , pp. 76-87
    • Jayaraman, L.1    Prives, C.2
  • 17
    • 70450235184 scopus 로고    scopus 로고
    • Regulation of p53-insights into a complex process
    • Boehme KA, Blattner C. Regulation of p53-insights into a complex process. Crit Rev Biochem Mol Biol. 2009;44(6):367-392.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , Issue.6 , pp. 367-392
    • Boehme, K.A.1    Blattner, C.2
  • 18
    • 77955858336 scopus 로고    scopus 로고
    • Posttranslational modification of p53: Cooperative integrators of function
    • Meek DW, Anderson CW. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb Perspect Biol. 2009;1(6):a000950.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. 6
    • Meek, D.W.1    Anderson, C.W.2
  • 19
    • 0842269247 scopus 로고    scopus 로고
    • The importance of p53 location: Nuclear or cytoplasmic zip code?
    • O'Brate A, Giannakakou P. The importance of p53 location: nuclear or cytoplasmic zip code? Drug Resist Updat. 2003;6(6): 313-322.
    • (2003) Drug Resist Updat , vol.6 , Issue.6 , pp. 313-322
    • O'Brate, A.1    Giannakakou, P.2
  • 20
    • 0027990725 scopus 로고
    • p53 domains: Structure, oligomerization, and transformation
    • Wang P, Reed M, Wang Y, et al. p53 domains: structure, oligomerization, and transformation. Mol Cell Biol. 1994;14(8):5182-5191.
    • (1994) Mol Cell Biol , vol.14 , Issue.8 , pp. 5182-5191
    • Wang, P.1    Reed, M.2    Wang, Y.3
  • 22
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 1991;51(23 Pt 1):6304-6311.
    • (1991) Cancer Res , vol.51 , Issue.23 PART 1 , pp. 6304-6311
    • Kastan, M.B.1    Onyekwere, O.2    Sidransky, D.3    Vogelstein, B.4    Craig, R.W.5
  • 23
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane DP. Cancer. p53, guardian of the genome. Nature. 1992; 358(6381):15-16.
    • (1992) Nature , vol.358 , Issue.6381 , pp. 15-16
    • Lane, D.P.1
  • 24
    • 0035810054 scopus 로고    scopus 로고
    • Regulation of the G2/M transition by p53
    • Taylor WR, Stark GR. Regulation of the G2/M transition by p53. Oncogene. 2001;20(15):1803-1815.
    • (2001) Oncogene , vol.20 , Issue.15 , pp. 1803-1815
    • Taylor, W.R.1    Stark, G.R.2
  • 25
    • 0028980494 scopus 로고
    • p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
    • Agarwal ML, Agarwal A, Taylor WR, Stark GR. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci U S A. 1995;92(18):8493-8497.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.18 , pp. 8493-8497
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Stark, G.R.4
  • 26
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 1993;75(4):817-825.
    • (1993) Cell , vol.75 , Issue.4 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 28
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther. 2002;1(8):639-649.
    • (2002) Mol Cancer Ther , vol.1 , Issue.8 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 29
    • 0031961995 scopus 로고    scopus 로고
    • Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: PRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • Niculescu AB, III, Chen X, Smeets M, Hengst L, Prives C, Reed SI. Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol. 1998;18(1):629-643.
    • (1998) Mol Cell Biol , vol.18 , Issue.1 , pp. 629-643
    • Niculescu III, A.B.1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 30
    • 0030743399 scopus 로고    scopus 로고
    • WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases
    • Ogryzko VV, Wong P, Howard BH. WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol Cell Biol. 1997;17(8):4877-4882.
    • (1997) Mol Cell Biol , vol.17 , Issue.8 , pp. 4877-4882
    • Ogryzko, V.V.1    Wong, P.2    Howard, B.H.3
  • 31
    • 0028220204 scopus 로고
    • p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • Dulic V, Kaufmann WK, Wilson SJ, et al. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell. 1994;76(6):1013-1023.
    • (1994) Cell , vol.76 , Issue.6 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3
  • 32
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell. 1995;82(4):675-684.
    • (1995) Cell , vol.82 , Issue.4 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 34
    • 0033711708 scopus 로고    scopus 로고
    • Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle
    • Ekholm SV, Reed SI. Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle. Curr Opin Cell Biol. 2000;12(6): 676-684.
    • (2000) Curr Opin Cell Biol , vol.12 , Issue.6 , pp. 676-684
    • Ekholm, S.V.1    Reed, S.I.2
  • 35
    • 44349136891 scopus 로고    scopus 로고
    • Telomere dysfunction and tumour suppression: The senescence connection
    • Deng Y, Chan SS, Chang S. Telomere dysfunction and tumour suppression: the senescence connection. Nat Rev Cancer. 2008; 8(6):450-458.
    • (2008) Nat Rev Cancer , vol.8 , Issue.6 , pp. 450-458
    • Deng, Y.1    Chan, S.S.2    Chang, S.3
  • 36
    • 84855888094 scopus 로고    scopus 로고
    • Regulation of senescence in cancer and aging
    • Kong Y, Cui H, Ramkumar C, Zhang H. Regulation of senescence in cancer and aging. J Aging Res. 2011;2011:963172.
    • (2011) J Aging Res , vol.2011 , pp. 963172
    • Kong, Y.1    Cui, H.2    Ramkumar, C.3    Zhang, H.4
  • 37
    • 55449119244 scopus 로고    scopus 로고
    • p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
    • Soria G, Speroni J, Podhajcer OL, Prives C, Gottifredi V. p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. J Cell Sci. 2008;121(Pt 19): 3271-3282.
    • (2008) J Cell Sci , vol.121 , Issue.PART 19 , pp. 3271-3282
    • Soria, G.1    Speroni, J.2    Podhajcer, O.L.3    Prives, C.4    Gottifredi, V.5
  • 38
    • 1242294418 scopus 로고    scopus 로고
    • Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block
    • Gottifredi V, McKinney K, Poyurovsky MV, Prives C. Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block. J Biol Chem. 2004;279(7):5802-5810.
    • (2004) J Biol Chem , vol.279 , Issue.7 , pp. 5802-5810
    • Gottifredi, V.1    McKinney, K.2    Poyurovsky, M.V.3    Prives, C.4
  • 40
    • 0031865131 scopus 로고    scopus 로고
    • Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C
    • Oku T, Ikeda S, Sasaki H, et al. Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C. Genes Cells. 1998;3(6):357-369.
    • (1998) Genes Cells , vol.3 , Issue.6 , pp. 357-369
    • Oku, T.1    Ikeda, S.2    Sasaki, H.3
  • 41
    • 0029016275 scopus 로고
    • Mechanism of inhibition of proliferating cell nuclear antigendependent DNA synthesis by the cyclin-dependent kinase inhibitor p21
    • Podust VN, Podust LM, Goubin F, Ducommun B, Hubscher U. Mechanism of inhibition of proliferating cell nuclear antigendependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. Biochemistry. 1995;34(27):8869-8875.
    • (1995) Biochemistry , vol.34 , Issue.27 , pp. 8869-8875
    • Podust, V.N.1    Podust, L.M.2    Goubin, F.3    Ducommun, B.4    Hubscher, U.5
  • 42
    • 0030587930 scopus 로고    scopus 로고
    • p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex
    • Chen U, Chen S, Saha P, Dutta A. p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex. Proc Natl Acad Sci U S A. 1996;93(21):11597-11602.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.21 , pp. 11597-11602
    • Chen, U.1    Chen, S.2    Saha, P.3    Dutta, A.4
  • 43
    • 0028899480 scopus 로고
    • Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
    • Chen J, Jackson PK, Kirschner MW, Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 1995;374(6520):386-388.
    • (1995) Nature , vol.374 , Issue.6520 , pp. 386-388
    • Chen, J.1    Jackson, P.K.2    Kirschner, M.W.3    Dutta, A.4
  • 44
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature. 1991;352(6333):345-347.
    • (1991) Nature , vol.352 , Issue.6333 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 45
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer. 2002;2(8):594-604.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 46
    • 21444432928 scopus 로고    scopus 로고
    • Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria
    • Arima Y, Nitta M, Kuninaka S, et al. Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria. J Biol Chem. 2005;280(19):19166-19176.
    • (2005) J Biol Chem , vol.280 , Issue.19 , pp. 19166-19176
    • Arima, Y.1    Nitta, M.2    Kuninaka, S.3
  • 47
    • 33745961862 scopus 로고    scopus 로고
    • The p53-Bcl-2 connection
    • Hemann MT, Lowe SW. The p53-Bcl-2 connection. Cell Death Differ. 2006;13(8):1256-1259.
    • (2006) Cell Death Differ , vol.13 , Issue.8 , pp. 1256-1259
    • Hemann, M.T.1    Lowe, S.W.2
  • 48
    • 0034717014 scopus 로고    scopus 로고
    • Death signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signaling
    • Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria: a potential role in apoptotic signaling. J Biol Chem. 2000;275(21):16202-16212.
    • (2000) J Biol Chem , vol.275 , Issue.21 , pp. 16202-16212
    • Marchenko, N.D.1    Zaika, A.2    Moll, U.M.3
  • 49
    • 38949105226 scopus 로고    scopus 로고
    • The hypoxic transcriptome of the retina: Identification of factors with potential neuroprotective activity
    • Thiersch M, Raffelsberger W, Frigg E, et al. The hypoxic transcriptome of the retina: identification of factors with potential neuroprotective activity. Adv Exp Med Biol. 2008;613:75-85.
    • (2008) Adv Exp Med Biol , vol.613 , pp. 75-85
    • Thiersch, M.1    Raffelsberger, W.2    Frigg, E.3
  • 50
    • 0038795317 scopus 로고    scopus 로고
    • Hypoxia attenuates the p53 response to cellular damage
    • Achison M, Hupp TR. Hypoxia attenuates the p53 response to cellular damage. Oncogene. 2003;22(22):3431-3440.
    • (2003) Oncogene , vol.22 , Issue.22 , pp. 3431-3440
    • Achison, M.1    Hupp, T.R.2
  • 51
    • 73649143160 scopus 로고    scopus 로고
    • A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages
    • Pearson BJ, Sanchez AA. A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages. Development. 2010;137(2):213-221.
    • (2010) Development , vol.137 , Issue.2 , pp. 213-221
    • Pearson, B.J.1    Sanchez, A.A.2
  • 52
    • 70349123829 scopus 로고    scopus 로고
    • The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
    • Cicalese A, Bonizzi G, Pasi CE, et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell. 2009;138(6):1083-1095.
    • (2009) Cell , vol.138 , Issue.6 , pp. 1083-1095
    • Cicalese, A.1    Bonizzi, G.2    Pasi, C.E.3
  • 53
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell. 2007;129(3):523-536.
    • (2007) Cell , vol.129 , Issue.3 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 54
    • 58049216794 scopus 로고    scopus 로고
    • p53 regulates hematopoietic stem cell quiescence
    • Liu Y, Elf SE, Miyata Y, et al. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell. 2009;4(1):37-48.
    • (2009) Cell Stem Cell , vol.4 , Issue.1 , pp. 37-48
    • Liu, Y.1    Elf, S.E.2    Miyata, Y.3
  • 55
    • 77955428416 scopus 로고    scopus 로고
    • NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
    • Zbinden M, Duquet A, Lorente-Trigos A, Ngwabyt SN, Borges I, Altaba A. NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J. 2010;29(15):2659-2674.
    • (2010) EMBO J , vol.29 , Issue.15 , pp. 2659-2674
    • Zbinden, M.1    Duquet, A.2    Lorente-Trigos, A.3    Ngwabyt, S.N.4    Borges, I.5    Altaba, A.6
  • 56
    • 77954464666 scopus 로고    scopus 로고
    • p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
    • Zhao Z, Zuber J, Diaz-Flores E, et al. p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal. Genes Dev. 2010;24(13):1389-1402.
    • (2010) Genes Dev , vol.24 , Issue.13 , pp. 1389-1402
    • Zhao, Z.1    Zuber, J.2    Diaz-Flores, E.3
  • 57
    • 79960022026 scopus 로고    scopus 로고
    • Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity
    • Wang YV, Leblanc M, Fox N, et al. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes Dev. 2011;25(13): 1426-1438.
    • (2011) Genes Dev , vol.25 , Issue.13 , pp. 1426-1438
    • Wang, Y.V.1    Leblanc, M.2    Fox, N.3
  • 58
    • 77949907107 scopus 로고    scopus 로고
    • p53-mediated hematopoietic stem and progenitor cell competition
    • Bondar T, Medzhitov R. p53-mediated hematopoietic stem and progenitor cell competition. Cell Stem Cell. 2010;6(4):309-322.
    • (2010) Cell Stem Cell , vol.6 , Issue.4 , pp. 309-322
    • Bondar, T.1    Medzhitov, R.2
  • 59
    • 77950563135 scopus 로고    scopus 로고
    • Irradiation selects for p53-deficient hematopoietic progenitors
    • Marusyk A, Porter CC, Zaberezhnyy V, DeGregori J. Irradiation selects for p53-deficient hematopoietic progenitors. PLoS Biol. 2010;8(3):e1000324.
    • (2010) PLoS Biol , vol.8 , Issue.3
    • Marusyk, A.1    Porter, C.C.2    Zaberezhnyy, V.3    Degregori, J.4
  • 60
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003;113(5):631-642.
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3
  • 61
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell. 1992;69(7):1237-1245.
    • (1992) Cell , vol.69 , Issue.7 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 62
    • 0023339504 scopus 로고
    • Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
    • Cahilly-Snyder L, Yang-Feng T, Francke U, George DL. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat Cell Mol Genet. 1987;13(3):235-244.
    • (1987) Somat Cell Mol Genet , vol.13 , Issue.3 , pp. 235-244
    • Cahilly-Snyder, L.1    Yang-Feng, T.2    Francke, U.3    George, D.L.4
  • 63
    • 0025853776 scopus 로고
    • Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
    • Fakharzadeh SS, Trusko SP, George DL. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J. 1991;10(6):1565-1569.
    • (1991) EMBO J , vol.10 , Issue.6 , pp. 1565-1569
    • Fakharzadeh, S.S.1    Trusko, S.P.2    George, D.L.3
  • 64
    • 0033523015 scopus 로고    scopus 로고
    • Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2
    • Maki CG. Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2. J Biol Chem. 1999;274(23):16531-16535.
    • (1999) J Biol Chem , vol.274 , Issue.23 , pp. 16531-16535
    • Maki, C.G.1
  • 65
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 1997;420(1): 25-27.
    • (1997) FEBS Lett , vol.420 , Issue.1 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 68
    • 10144259344 scopus 로고    scopus 로고
    • MDMX: A novel p53-binding protein with some functional properties of MDM2
    • Shvarts A, Steegenga WT, Riteco N, et al. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 1996;15(19):5349-5357.
    • (1996) EMBO J , vol.15 , Issue.19 , pp. 5349-5357
    • Shvarts, A.1    Steegenga, W.T.2    Riteco, N.3
  • 69
    • 0033621415 scopus 로고    scopus 로고
    • Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein
    • Sharp DA, Kratowicz SA, Sank MJ, George DL. Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein. J Biol Chem. 1999;274(53):38189-38196.
    • (1999) J Biol Chem , vol.274 , Issue.53 , pp. 38189-38196
    • Sharp, D.A.1    Kratowicz, S.A.2    Sank, M.J.3    George, D.L.4
  • 71
    • 0037205454 scopus 로고    scopus 로고
    • Mutual dependence of MDM2 and MDMX in their functional inactivation of p53
    • Gu J, Kawai H, Nie L, et al. Mutual dependence of MDM2 and MDMX in their functional inactivation of p53. J Biol Chem. 2002;277(22):19251-19254.
    • (2002) J Biol Chem , vol.277 , Issue.22 , pp. 19251-19254
    • Gu, J.1    Kawai, H.2    Nie, L.3
  • 72
    • 67650501132 scopus 로고    scopus 로고
    • MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway
    • Mancini F, Di CG, Pellegrino M, et al. MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway. EMBO J. 2009;28(13):1926-1939.
    • (2009) EMBO J , vol.28 , Issue.13 , pp. 1926-1939
    • Mancini, F.1    Di, C.G.2    Pellegrino, M.3
  • 73
    • 43049163953 scopus 로고    scopus 로고
    • Acetylation is indispensable for p53 activation
    • Tang Y, Zhao W, Chen Y, Zhao Y, Gu W. Acetylation is indispensable for p53 activation. Cell. 2008;133(4):612-626.
    • (2008) Cell , vol.133 , Issue.4 , pp. 612-626
    • Tang, Y.1    Zhao, W.2    Chen, Y.3    Zhao, Y.4    Gu, W.5
  • 74
    • 0025943945 scopus 로고
    • Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein
    • Shi Y, Seto E, Chang LS, Shenk T. Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein. Cell. 1991;67(2):377-388.
    • (1991) Cell , vol.67 , Issue.2 , pp. 377-388
    • Shi, Y.1    Seto, E.2    Chang, L.S.3    Shenk, T.4
  • 75
    • 0030941901 scopus 로고    scopus 로고
    • Everything you have ever wanted to know about Yin Yang 1
    • Shi Y, Lee JS, Galvin KM. Everything you have ever wanted to know about Yin Yang 1. Biochim Biophys Acta. 1997;1332(2): F49-F66.
    • (1997) Biochim Biophys Acta , vol.1332 , Issue.2
    • Shi, Y.1    Lee, J.S.2    Galvin, K.M.3
  • 76
    • 17644367515 scopus 로고    scopus 로고
    • Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis
    • Krippner-Heidenreich A, Walsemann G, Beyrouthy MJ, et al. Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis. Mol Cell Biol. 2005;25(9):3704-3714.
    • (2005) Mol Cell Biol , vol.25 , Issue.9 , pp. 3704-3714
    • Krippner-Heidenreich, A.1    Walsemann, G.2    Beyrouthy, M.J.3
  • 77
    • 0029850458 scopus 로고    scopus 로고
    • Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
    • Yang WM, Inouye C, Zeng Y, Bearss D, Seto E. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc Natl Acad Sci U S A. 1996;93(23):12845-12850.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.23 , pp. 12845-12850
    • Yang, W.M.1    Inouye, C.2    Zeng, Y.3    Bearss, D.4    Seto, E.5
  • 78
    • 4344601100 scopus 로고    scopus 로고
    • YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress
    • Gronroos E, Terentiev AA, Punga T, Ericsson J. YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress. Proc Natl Acad Sci U S A. 2004;101(33):12165-12170.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.33 , pp. 12165-12170
    • Gronroos, E.1    Terentiev, A.A.2    Punga, T.3    Ericsson, J.4
  • 79
    • 2442548716 scopus 로고    scopus 로고
    • p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels
    • Iyer NG, Chin SF, Ozdag H, et al. p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels. Proc Natl Acad Sci U S A. 2004; 101(19):7386-7391.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.19 , pp. 7386-7391
    • Iyer, N.G.1    Chin, S.F.2    Ozdag, H.3
  • 81
    • 0032185124 scopus 로고    scopus 로고
    • p300/MDM2 complexes participate in MDM2-mediated p53 degradation
    • Grossman SR, Perez M, Kung AL, et al. p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell. 1998; 2(4):405-415.
    • (1998) Mol Cell , vol.2 , Issue.4 , pp. 405-415
    • Grossman, S.R.1    Perez, M.2    Kung, A.L.3
  • 82
    • 2942702012 scopus 로고    scopus 로고
    • Yin Yang 1 is a negative regulator of p53
    • Sui G, Affar EB, Shi Y, et al. Yin Yang 1 is a negative regulator of p53. Cell. 2004;117(7):859-872.
    • (2004) Cell , vol.117 , Issue.7 , pp. 859-872
    • Sui, G.1    Affar, E.B.2    Shi, Y.3
  • 83
    • 77955904320 scopus 로고    scopus 로고
    • Retinoblastoma
    • Lohmann D. Retinoblastoma. Adv Exp Med Biol. 2010;685:220-227.
    • (2010) Adv Exp Med Biol , vol.685 , pp. 220-227
    • Lohmann, D.1
  • 84
    • 33750596704 scopus 로고    scopus 로고
    • Cancer biology: Second step to retinal tumours
    • Wallace VA. Cancer biology: second step to retinal tumours. Nature. 2006;444(7115):45-46.
    • (2006) Nature , vol.444 , Issue.7115 , pp. 45-46
    • Wallace, V.A.1
  • 85
    • 0029908550 scopus 로고    scopus 로고
    • Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation
    • Sidle A, Palaty C, Dirks P, et al. Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation. Crit Rev Biochem Mol Biol. 1996;31(3): 237-271.
    • (1996) Crit Rev Biochem Mol Biol , vol.31 , Issue.3 , pp. 237-271
    • Sidle, A.1    Palaty, C.2    Dirks, P.3
  • 86
    • 13444249786 scopus 로고    scopus 로고
    • The search for the retinoblastoma cell of origin
    • Dyer MA, Bremner R. The search for the retinoblastoma cell of origin. Nat Rev Cancer. 2005;5(2):91-101.
    • (2005) Nat Rev Cancer , vol.5 , Issue.2 , pp. 91-101
    • Dyer, M.A.1    Bremner, R.2
  • 87
    • 55249118800 scopus 로고    scopus 로고
    • A dynamic reciprocal RBR-PRC2 regulatory circuit controls Arabidopsis gametophyte development
    • Johnston AJ, Matveeva E, Kirioukhova O, Grossniklaus U, Gruissem W. A dynamic reciprocal RBR-PRC2 regulatory circuit controls Arabidopsis gametophyte development. Curr Biol. 2008; 18(21):1680-1686.
    • (2008) Curr Biol , vol.18 , Issue.21 , pp. 1680-1686
    • Johnston, A.J.1    Matveeva, E.2    Kirioukhova, O.3    Grossniklaus, U.4    Gruissem, W.5
  • 88
    • 29244464678 scopus 로고    scopus 로고
    • The retinoblastoma-related gene regulates stem cell maintenance in Arabidopsis roots
    • Wildwater M, Campilho A, Perez-Perez JM, et al. The retinoblastoma-related gene regulates stem cell maintenance in Arabidopsis roots. Cell. 2005;123(7):1337-1349.
    • (2005) Cell , vol.123 , Issue.7 , pp. 1337-1349
    • Wildwater, M.1    Campilho, A.2    Perez-Perez, J.M.3
  • 89
    • 70349437076 scopus 로고    scopus 로고
    • p53 and E2f: Partners in life and death
    • Polager S, Ginsberg D. p53 and E2f: partners in life and death. Nat Rev Cancer. 2009;9(10):738-748.
    • (2009) Nat Rev Cancer , vol.9 , Issue.10 , pp. 738-748
    • Polager, S.1    Ginsberg, D.2
  • 90
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson DG, Schwarz JK, Cress WD, Nevins JR. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature. 1993;365(6444):349-352.
    • (1993) Nature , vol.365 , Issue.6444 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 91
    • 33750590095 scopus 로고    scopus 로고
    • Inactivation of the p53 pathway in retinoblastoma
    • Laurie NA, Donovan SL, Shih CS, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444(7115):61-66.
    • (2006) Nature , vol.444 , Issue.7115 , pp. 61-66
    • Laurie, N.A.1    Donovan, S.L.2    Shih, C.S.3
  • 92
    • 0036898541 scopus 로고    scopus 로고
    • Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling
    • Langheinrich U, Hennen E, Stott G, Vacun G. Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling. Curr Biol. 2002;12(23):2023-2028.
    • (2002) Curr Biol , vol.12 , Issue.23 , pp. 2023-2028
    • Langheinrich, U.1    Hennen, E.2    Stott, G.3    Vacun, G.4
  • 93
    • 19944426854 scopus 로고    scopus 로고
    • tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors
    • Berghmans S, Murphey RD, Wienholds E, et al. tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proc Natl Acad Sci U S A. 2005;102(2):407-412.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.2 , pp. 407-412
    • Berghmans, S.1    Murphey, R.D.2    Wienholds, E.3
  • 94
    • 0029347164 scopus 로고
    • High-frequency developmental abnormalities in p53-deficient mice
    • Armstrong JF, Kaufman MH, Harrison DJ, Clarke AR. High-frequency developmental abnormalities in p53-deficient mice. Curr Biol. 1995;5(8):931-936.
    • (1995) Curr Biol , vol.5 , Issue.8 , pp. 931-936
    • Armstrong, J.F.1    Kaufman, M.H.2    Harrison, D.J.3    Clarke, A.R.4
  • 96
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 1999;398(6729):708-713.
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 97
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature. 1999;398(6729):714-718.
    • (1999) Nature , vol.398 , Issue.6729 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3
  • 98
    • 0036001336 scopus 로고    scopus 로고
    • Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm
    • Bakkers J, Hild M, Kramer C, Furutani-Seiki M, Hammerschmidt M. Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm. Dev Cell. 2002;2(5):617-627.
    • (2002) Dev Cell , vol.2 , Issue.5 , pp. 617-627
    • Bakkers, J.1    Hild, M.2    Kramer, C.3    Furutani-Seiki, M.4    Hammerschmidt, M.5
  • 99
    • 0036114018 scopus 로고    scopus 로고
    • A dominant-negative form of p63 is required for epidermal proliferation in zebrafish
    • Lee H, Kimelman D. A dominant-negative form of p63 is required for epidermal proliferation in zebrafish. Dev Cell. 2002;2(5):607-616.
    • (2002) Dev Cell , vol.2 , Issue.5 , pp. 607-616
    • Lee, H.1    Kimelman, D.2
  • 100
    • 17544363909 scopus 로고    scopus 로고
    • p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
    • Yang A, Walker N, Bronson R, et al. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature. 2000;404(6773):99-103.
    • (2000) Nature , vol.404 , Issue.6773 , pp. 99-103
    • Yang, A.1    Walker, N.2    Bronson, R.3
  • 101
    • 0344196811 scopus 로고    scopus 로고
    • Specific and conserved roles of TAp73 during zebrafish development
    • Rentzsch F, Kramer C, Hammerschmidt M. Specific and conserved roles of TAp73 during zebrafish development. Gene. 2003; 323:19-30.
    • (2003) Gene , vol.323 , pp. 19-30
    • Rentzsch, F.1    Kramer, C.2    Hammerschmidt, M.3
  • 102
  • 103
    • 0029767029 scopus 로고    scopus 로고
    • p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells
    • Eizenberg O, Faber-Elman A, Gottlieb E, Oren M, Rotter V, Schwartz M. p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol Cell Biol. 1996;16(9):5178-5185.
    • (1996) Mol Cell Biol , vol.16 , Issue.9 , pp. 5178-5185
    • Eizenberg, O.1    Faber-Elman, A.2    Gottlieb, E.3    Oren, M.4    Rotter, V.5    Schwartz, M.6
  • 104
    • 0028118111 scopus 로고
    • Tumor spectrum analysis in p53-mutant mice
    • Jacks T, Remington L, Williams BO, et al. Tumor spectrum analysis in p53-mutant mice. Curr Biol. 1994;4(1):1-7.
    • (1994) Curr Biol , vol.4 , Issue.1 , pp. 1-7
    • Jacks, T.1    Remington, L.2    Williams, B.O.3
  • 105
    • 0031847947 scopus 로고    scopus 로고
    • High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice
    • Reichel MB, Ali RR, D'Esposito F, et al. High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. Cell Death Differ. 1998;5(2):156-162.
    • (1998) Cell Death Differ , vol.5 , Issue.2 , pp. 156-162
    • Reichel, M.B.1    Ali, R.R.2    D'Esposito, F.3
  • 107
    • 0034111311 scopus 로고    scopus 로고
    • Degeneration of cone photoreceptors induced by expression of the Mas1 protooncogene
    • Xu X, Quiambao AB, Roveri L, et al. Degeneration of cone photoreceptors induced by expression of the Mas1 protooncogene. Exp Neurol. 2000;163(1):207-219.
    • (2000) Exp Neurol , vol.163 , Issue.1 , pp. 207-219
    • Xu, X.1    Quiambao, A.B.2    Roveri, L.3
  • 109
    • 0021830601 scopus 로고
    • Cell differentiation in the retina of the mouse
    • Young RW. Cell differentiation in the retina of the mouse. Anat Rec. 1985;212(2):199-205.
    • (1985) Anat Rec , vol.212 , Issue.2 , pp. 199-205
    • Young, R.W.1
  • 110
    • 0021679078 scopus 로고
    • Cell death during differentiation of the retina in the mouse
    • Young RW. Cell death during differentiation of the retina in the mouse. J Comp Neurol. 1984;229(3):362-373.
    • (1984) J Comp Neurol , vol.229 , Issue.3 , pp. 362-373
    • Young, R.W.1
  • 111
    • 0032828720 scopus 로고    scopus 로고
    • Tissue-specific p53 expression in the nervous system
    • Tendler Y, Weisinger G, Coleman R, et al. Tissue-specific p53 expression in the nervous system. Brain Res Mol Brain Res. 1999;72(1):40-46.
    • (1999) Brain Res Mol Brain Res , vol.72 , Issue.1 , pp. 40-46
    • Tendler, Y.1    Weisinger, G.2    Coleman, R.3
  • 112
    • 0033551564 scopus 로고    scopus 로고
    • In situ localization of p53, bcl-2 and bax mRNAs in rat ocular tissue
    • Shin DH, Lee HY, Lee HW, et al. In situ localization of p53, bcl-2 and bax mRNAs in rat ocular tissue. Neuroreport. 1999;10(10): 2165-2167.
    • (1999) Neuroreport , vol.10 , Issue.10 , pp. 2165-2167
    • Shin, D.H.1    Lee, H.Y.2    Lee, H.W.3
  • 114
    • 0015151632 scopus 로고
    • A histochemical study of cellular reactions in rat retina transiently damaged by visible light
    • Hansson HA. A histochemical study of cellular reactions in rat retina transiently damaged by visible light. Exp Eye Res. 1971; 12(3):270-274.
    • (1971) Exp Eye Res , vol.12 , Issue.3 , pp. 270-274
    • Hansson, H.A.1
  • 115
    • 58949091294 scopus 로고    scopus 로고
    • Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light
    • Westlund BS, Cai B, Zhou J, Sparrow JR. Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light. Apoptosis. 2009;14(1):31-41.
    • (2009) Apoptosis , vol.14 , Issue.1 , pp. 31-41
    • Westlund, B.S.1    Cai, B.2    Zhou, J.3    Sparrow, J.R.4
  • 116
    • 0031967933 scopus 로고    scopus 로고
    • Light-induced cell death of retinal photoreceptors in the absence of p53
    • Marti A, Hafezi F, Lansel N, et al. Light-induced cell death of retinal photoreceptors in the absence of p53. Invest Ophthalmol Vis Sci. 1998;39(5):846-849.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.5 , pp. 846-849
    • Marti, A.1    Hafezi, F.2    Lansel, N.3
  • 117
  • 118
    • 33751103471 scopus 로고    scopus 로고
    • Age-related macular degeneration-emerging pathogenetic and therapeutic concepts
    • Gehrs KM, Anderson DH, Johnson LV, Hageman GS. Age-related macular degeneration-emerging pathogenetic and therapeutic concepts. Ann Med. 2006;38(7):450-471.
    • (2006) Ann Med , vol.38 , Issue.7 , pp. 450-471
    • Gehrs, K.M.1    Anderson, D.H.2    Johnson, L.V.3    Hageman, G.S.4
  • 119
    • 0035069027 scopus 로고    scopus 로고
    • Fundus autofluorescence and development of geographic atrophy in agerelated macular degeneration
    • Holz FG, Bellman C, Staudt S, Schutt F, Volcker HE. Fundus autofluorescence and development of geographic atrophy in agerelated macular degeneration. Invest Ophthalmol Vis Sci. 2001; 42(5):1051-1056.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.5 , pp. 1051-1056
    • Holz, F.G.1    Bellman, C.2    Staudt, S.3    Schutt, F.4    Volcker, H.E.5
  • 120
    • 0344830731 scopus 로고    scopus 로고
    • Fundus autofluorescence in agerelated macular disease imaged with a laser scanning ophthalmoscope
    • von RA, Fitzke FW, Bird AC. Fundus autofluorescence in agerelated macular disease imaged with a laser scanning ophthalmoscope. Invest Ophthalmol Vis Sci. 1997;38(2):478-486.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , Issue.2 , pp. 478-486
    • Von, R.A.1    Fitzke, F.W.2    Bird, A.C.3
  • 122
    • 2442660386 scopus 로고    scopus 로고
    • Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53
    • Borges HL, Chao C, Xu Y, Linden R, Wang JY. Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53. Cell Death Differ. 2004;11(5):494-502.
    • (2004) Cell Death Differ , vol.11 , Issue.5 , pp. 494-502
    • Borges, H.L.1    Chao, C.2    Xu, Y.3    Linden, R.4    Wang, J.Y.5
  • 123
    • 0030910037 scopus 로고    scopus 로고
    • p53 and ATM: Cell cycle, cell death, and cancer
    • Morgan SE, Kastan MB. p53 and ATM: cell cycle, cell death, and cancer. Adv Cancer Res. 1997;71:1-25.
    • (1997) Adv Cancer Res , vol.71 , pp. 1-25
    • Morgan, S.E.1    Kastan, M.B.2
  • 124
    • 0033490280 scopus 로고    scopus 로고
    • Gamma irradiation leads to two waves of apoptosis in distinct cell populations of the retina of newborn rats
    • Borges HL, Linden R. Gamma irradiation leads to two waves of apoptosis in distinct cell populations of the retina of newborn rats. J Cell Sci. 1999;112 (Pt 23):4315-4324.
    • (1999) J Cell Sci , vol.112 , Issue.PART 23 , pp. 4315-4324
    • Borges, H.L.1    Linden, R.2
  • 125
    • 0020525981 scopus 로고
    • Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina
    • Wiegand RD, Giusto NM, Rapp LM, Anderson RE. Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina. Invest Ophthalmol Vis Sci. 1983;24(10): 1433-1435.
    • (1983) Invest Ophthalmol Vis Sci , vol.24 , Issue.10 , pp. 1433-1435
    • Wiegand, R.D.1    Giusto, N.M.2    Rapp, L.M.3    Anderson, R.E.4
  • 126
    • 0031807228 scopus 로고    scopus 로고
    • Light history and age-related changes in retinal light damage
    • Organisciak DT, Darrow RM, Barsalou L, et al. Light history and age-related changes in retinal light damage. Invest Ophthalmol Vis Sci. 1998;39(7):1107-1116.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.7 , pp. 1107-1116
    • Organisciak, D.T.1    Darrow, R.M.2    Barsalou, L.3
  • 127
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol. 2000;45(2):115-134.
    • (2000) Surv Ophthalmol , vol.45 , Issue.2 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3    Henson, D.4    Boulton, M.5
  • 128
    • 19044370231 scopus 로고    scopus 로고
    • Role of oxidative stress enzymes in open-angle glaucoma
    • Yildirim O, Ates NA, Ercan B, et al. Role of oxidative stress enzymes in open-angle glaucoma. Eye (Lond). 2005;19(5):580-3.
    • (2005) Eye (Lond) , vol.19 , Issue.5 , pp. 580-583
    • Yildirim, O.1    Ates, N.A.2    Ercan, B.3
  • 129
    • 0021344066 scopus 로고
    • Molecular mechanism of cataractogenesis: III. Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract
    • Bhuyan KC, Bhuyan DK. Molecular mechanism of cataractogenesis: III. Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract. Curr Eye Res. 1984;3(1):67-81.
    • (1984) Curr Eye Res , vol.3 , Issue.1 , pp. 67-81
    • Bhuyan, K.C.1    Bhuyan, D.K.2
  • 130
    • 27144478049 scopus 로고    scopus 로고
    • Oxidative stress in ocular disease: Does lutein play a protective role?
    • Santosa S, Jones PJ. Oxidative stress in ocular disease: does lutein play a protective role? CMAJ. 2005;173(8):861-862.
    • (2005) CMAJ , vol.173 , Issue.8 , pp. 861-862
    • Santosa, S.1    Jones, P.J.2
  • 131
    • 0031691249 scopus 로고    scopus 로고
    • Nitro-imidazole radiosensitizer-induced toxicity in cynomolgus monkeys
    • Breider MA, Ulloa HM, Pegg DG, Gough AW. Nitro-imidazole radiosensitizer-induced toxicity in cynomolgus monkeys. Toxicol Pathol. 1998;26(5):651-656.
    • (1998) Toxicol Pathol , vol.26 , Issue.5 , pp. 651-656
    • Breider, M.A.1    Ulloa, H.M.2    Pegg, D.G.3    Gough, A.W.4
  • 132
    • 0034652379 scopus 로고    scopus 로고
    • Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice
    • Lee AE, Wilson WR. Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice. Toxicol Appl Pharmacol. 2000;163(1):50-59.
    • (2000) Toxicol Appl Pharmacol , vol.163 , Issue.1 , pp. 50-59
    • Lee, A.E.1    Wilson, W.R.2
  • 133
    • 28544433163 scopus 로고    scopus 로고
    • Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3
    • Miller TJ, Schneider RJ, Miller JA, et al. Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3. Neurotoxicology. 2006;27(1):44-59.
    • (2006) Neurotoxicology , vol.27 , Issue.1 , pp. 44-59
    • Miller, T.J.1    Schneider, R.J.2    Miller, J.A.3
  • 134
    • 53449086160 scopus 로고    scopus 로고
    • A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell
    • O'Connor JC, Wallace DM, O'Brien CJ, Cotter TG. A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell. Invest Ophthalmol Vis Sci. 2008;49(10):4237-4244.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.10 , pp. 4237-4244
    • O'Connor, J.C.1    Wallace, D.M.2    O'Brien, C.J.3    Cotter, T.G.4
  • 135
    • 0033052291 scopus 로고    scopus 로고
    • Necrosis and apoptosis after retinal ischemia: Involvement of NMDA-mediated excitotoxicity and p53
    • Joo CK, Choi JS, Ko HW, et al. Necrosis and apoptosis after retinal ischemia: involvement of NMDA-mediated excitotoxicity and p53. Invest Ophthalmol Vis Sci. 1999;40(3):713-720.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.3 , pp. 713-720
    • Joo, C.K.1    Choi, J.S.2    Ko, H.W.3
  • 136
    • 0031708027 scopus 로고    scopus 로고
    • The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia
    • Rosenbaum DM, Rosenbaum PS, Gupta H, et al. The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia. Invest Ophthalmol Vis Sci. 1998;39(11): 2132-2139.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.11 , pp. 2132-2139
    • Rosenbaum, D.M.1    Rosenbaum, P.S.2    Gupta, H.3
  • 137
    • 77952484413 scopus 로고    scopus 로고
    • Hypoxia-ischemia and retinal ganglion cell damage
    • Kaur C, Foulds WS, Ling EA. Hypoxia-ischemia and retinal ganglion cell damage. Clin Ophthalmol. 2008;2(4):879-889.
    • (2008) Clin Ophthalmol , vol.2 , Issue.4 , pp. 879-889
    • Kaur, C.1    Foulds, W.S.2    Ling, E.A.3
  • 139
    • 84927571602 scopus 로고
    • Retinitis pigmentosa overview
    • In: Pagon RS, Bird TD, Dolan CR, Stephens K, eds, Seattle, WA: University of Washington, Seattle, [updated September 16, 2005]
    • Pagon RA, Daiger SP. Retinitis pigmentosa overview. In: Pagon RS, Bird TD, Dolan CR, Stephens K, eds. GeneReviews. Seattle, WA: University of Washington, Seattle; 1993-2002 [updated September 16, 2005].
    • (1993) GeneReviews
    • Pagon, R.A.1    Daiger, S.P.2
  • 140
    • 34147097300 scopus 로고    scopus 로고
    • Retinitis pigmentosa
    • Hamel C. Retinitis pigmentosa. Orphanet J Rare Dis. 2006;1:40.
    • (2006) Orphanet J Rare Dis , vol.1 , pp. 40
    • Hamel, C.1
  • 141
    • 77954621518 scopus 로고    scopus 로고
    • The molecular basis of human retinal and vitreoretinal diseases
    • Berger W, Kloeckener-Gruissem B, Neidhardt J. The molecular basis of human retinal and vitreoretinal diseases. Prog Retin Eye Res. 2010;29(5):335-375.
    • (2010) Prog Retin Eye Res , vol.29 , Issue.5 , pp. 335-375
    • Berger, W.1    Kloeckener-Gruissem, B.2    Neidhardt, J.3
  • 142
    • 0026072333 scopus 로고
    • Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse
    • Pittler SJ, Baehr W. Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse. Proc Natl Acad Sci U S A. 1991;88(19): 8322-8326.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.19 , pp. 8322-8326
    • Pittler, S.J.1    Baehr, W.2
  • 144
    • 0035789540 scopus 로고    scopus 로고
    • Rod and cone degeneration in the rd mouse is p53 independent
    • Wu J, Trogadis J, Bremner R. Rod and cone degeneration in the rd mouse is p53 independent. Mol Vis. 2001;7:101-106.
    • (2001) Mol Vis , vol.7 , pp. 101-106
    • Wu, J.1    Trogadis, J.2    Bremner, R.3
  • 145
    • 77649248174 scopus 로고    scopus 로고
    • N-methyl-N-nitrosourea-induced retinal degeneration in mice is independent of the p53 gene
    • Yoshizawa K, Kuwata M, Kawanaka A, Uehara N, Yuri T, Tsubura A. N-methyl-N-nitrosourea-induced retinal degeneration in mice is independent of the p53 gene. Mol Vis. 2009;15:2919-2925.
    • (2009) Mol Vis , vol.15 , pp. 2919-2925
    • Yoshizawa, K.1    Kuwata, M.2    Kawanaka, A.3    Uehara, N.4    Yuri, T.5    Tsubura, A.6
  • 146
    • 0031679636 scopus 로고    scopus 로고
    • Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse
    • Ali RR, Reichel MB, Kanuga N, et al. Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse. Curr Eye Res. 1998;17(9):917-923.
    • (1998) Curr Eye Res , vol.17 , Issue.9 , pp. 917-923
    • Ali, R.R.1    Reichel, M.B.2    Kanuga, N.3
  • 147
    • 0018582251 scopus 로고
    • Rods and cones in the mouse retina. II. Autoradiographic analysis of cell generation using tritiated thymidine
    • Carter-Dawson LD, LaVail MM. Rods and cones in the mouse retina. II. Autoradiographic analysis of cell generation using tritiated thymidine. J Comp Neurol. 1979;188(2):263-272.
    • (1979) J Comp Neurol , vol.188 , Issue.2 , pp. 263-272
    • Carter-Dawson, L.D.1    Lavail, M.M.2


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