-
1
-
-
33751103471
-
Age-related macular degeneration - Emerging pathogenetic and therapeutic concepts
-
DOI 10.1080/07853890600946724, PII P30P0084J262W715
-
Gehrs KM, Anderson DH, Johnson LV et al (2006) Age-related macular degeneration-emerging pathogenetic and therapeutic concepts. Ann Med 38:450-471. doi:10.1080/078538906009 46724 (Pubitemid 44767496)
-
(2006)
Annals of Medicine
, vol.38
, Issue.7
, pp. 450-471
-
-
Gehrs, K.M.1
Anderson, D.H.2
Johnson, L.V.3
Hageman, G.S.4
-
2
-
-
0035069027
-
Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration
-
Holz FG, Bellman C, Staudt S et al (2001) Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci 42:1051-1056 (Pubitemid 32289803)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.5
, pp. 1051-1056
-
-
Holz, F.G.1
Bellman, C.2
Staudt, S.3
Schutt, F.4
Volcker, H.E.5
-
4
-
-
18044366931
-
RPE lipofuscin and its role in retinal pathobiology
-
DOI 10.1016/j.exer.2005.01.007
-
Sparrow JR, Boulton M (2005) RPE lipofuscin and its role in retinal pathobiology. Exp Eye Res 80:595-606. doi:10.1016/j. exer.2005.01.007 (Pubitemid 40602960)
-
(2005)
Experimental Eye Research
, vol.80
, Issue.5
, pp. 595-606
-
-
Sparrow, J.R.1
Boulton, M.2
-
5
-
-
47849116874
-
Rpe lipofuscin: Formation, properties and relevance to retinal degeneration
-
In Tombran-Tink J, Barnstable CJ (eds) Humana Press, Totowa, NJ
-
Sparrow JR (2007) RPE lipofuscin: formation, properties and relevance to retinal degeneration. In: Tombran-Tink J, Barnstable CJ (eds) Retinal degenerations: biology, diagnostics and therapeutics. Humana Press, Totowa, NJ
-
(2007)
Retinal degenerations: biology, diagnostics and therapeutics
-
-
Sparrow, J.R.1
-
6
-
-
0036495230
-
Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement
-
DOI 10.1002/1521-3773(20020301)41:5<814::AID-ANIE814>3.0.CO;2-2
-
Ben-Shabat S, Itagaki Y, Jockusch S et al (2002) Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement. Angew Chem Int Ed Engl 41:814-817. doi:10.1002/1521- 3773(20020301)41:5\814::AID-ANIE814[3.0.CO;2-2 (Pubitemid 34218533)
-
(2002)
Angewandte Chemie - International Edition
, vol.41
, Issue.5
, pp. 814-817
-
-
Ben-Shabat, S.1
Itagaki, Y.2
Jockusch, S.3
Sparrow, J.R.4
Turro, N.J.5
Nakanishi, K.6
-
7
-
-
0036205219
-
Involvement of oxidative mechanisms in blue-light-Induced damage to A2e-laden RPE
-
Sparrow JR, Zhou J, Ben-Shabat S et al (2002) Involvement of oxidative mechanisms in blue-light-induced damage to A2Eladen RPE. Invest Ophthalmol Vis Sci 43:1222-1227 (Pubitemid 34258296)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.4
, pp. 1222-1227
-
-
Sparrow, J.R.1
Zhou, J.2
Ben-Shabat, S.3
Vollmer, H.4
Itagaki, Y.5
Nakanishi, K.6
-
8
-
-
0037408428
-
DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination
-
DOI 10.1167/iovs.02-0746
-
Sparrow JR, Zhou J, Cai B (2003) DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination. Invest Ophthalmol Vis Sci 44:2245-2251. doi: 10.1167/iovs.02-0746 (Pubitemid 36520323)
-
(2003)
Investigative Ophthalmology and Visual Science
, vol.44
, Issue.5
, pp. 2245-2251
-
-
Sparrow, J.R.1
Zhou, J.2
Cai, B.3
-
9
-
-
0037705336
-
A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation
-
DOI 10.1074/jbc.M300457200
-
Sparrow JR, Vollmer-Snarr HR, Zhou J et al (2003) A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J Biol Chem 278:18207-18213. doi:10.1074/jbc.M300457200 (Pubitemid 36799437)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 18207-18213
-
-
Sparrow, J.R.1
Vollmer-Snarr, H.R.2
Zhou, J.3
Jang, Y.P.4
Jockusch, S.5
Itagaki, Y.6
Nakanishi, K.7
-
10
-
-
0035040640
-
Blue light-induced apoptosis of A2E-containing RPE: Involvement of caspase-3 and protection by Bcl-2
-
Sparrow JR, Cai B (2001) Blue light-induced apoptosis of A2Econtaining RPE: involvement of caspase-3 and protection by Bcl- 2. Invest Ophthalmol Vis Sci 42:1356-1362 (Pubitemid 32381981)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.6
, pp. 1356-1362
-
-
Sparrow, J.R.1
Cai, B.2
-
11
-
-
0036391801
-
The abl family kinases: Mechanisms of regulation and signaling
-
doi: 10.1016/S0065-230X(02)85003-5
-
Pendergast AM (2002) The Abl family kinases: mechanisms of regulation and signaling. Adv Cancer Res 85:51-100. doi: 10.1016/S0065-230X(02)85003-5
-
(2002)
Adv Cancer Res
, vol.85
, pp. 51-100
-
-
Pendergast, A.M.1
-
12
-
-
0028233970
-
The nuclear tyrosine kinase c-Abl negatively regulates cell growth
-
DOI 10.1016/0092-8674(94)90240-2
-
Sawyers CL, McLaughlin J, Goga A et al (1994) The nuclear tyrosine kinase c-Abl negatively regulates cell growth. Cell 77:121-131. doi:10.1016/0092- 8674(94)90240-2 (Pubitemid 24184693)
-
(1994)
Cell
, vol.77
, Issue.1
, pp. 121-131
-
-
Sawyers, C.L.1
McLaughlin, J.2
Goga, A.3
Havlik, M.4
Witte, O.5
-
13
-
-
0029024327
-
Deregulation of c-abl mediated cell growth after retroviral transfer and expression of antisense sequences
-
Daniel R, Cai Y, Wong PM et al (1995) Deregulation of c-abl mediated cell growth after retroviral transfer and expression of antisense sequences. Oncogene 10:1607-1614
-
(1995)
Oncogene
, vol.10
, pp. 1607-1614
-
-
Daniel, R.1
Cai, Y.2
Wong, P.M.3
-
14
-
-
0032937828
-
Cycling, stressed-out and nervous: Cellular functions of c-Abl
-
DOI 10.1016/S0962-8924(99)01549-4
-
Van Etten RA (1999) Cycling, stressed-out and nervous: cellular functions of c-Abl. Trends Cell Biol 9:179-186. doi:10.1016/ S0962-8924(99)01549-4 (Pubitemid 29192985)
-
(1999)
Trends in Cell Biology
, vol.9
, Issue.5
, pp. 179-186
-
-
Van Etten, R.A.1
-
15
-
-
0034693878
-
Regulation of cell death by the abl tyrosine kinase
-
doi:10.1038/sj.onc.1203878
-
Wang JY (2000) Regulation of cell death by the Abl tyrosine kinase. Oncogene 19:5643-5650. doi:10.1038/sj.onc.1203878
-
(2000)
Oncogene
, vol.19
, pp. 5643-5650
-
-
Wang, J.Y.1
-
16
-
-
0344626925
-
A myristoyl/phosphotyrosine switch regulates c-Abl
-
DOI 10.1016/S0092-8674(03)00191-0
-
Hantschel O, Nagar B, Guettler S et al (2003) A myristoyl/ phosphotyrosine switch regulates c-Abl. Cell 112:845-857. doi: 10.1016/S0092-8674(03)00191-0 (Pubitemid 36378886)
-
(2003)
Cell
, vol.112
, Issue.6
, pp. 845-857
-
-
Hantschel, O.1
Nagar, B.2
Guettler, S.3
Kretzschmar, J.4
Dorey, K.5
Kuriyan, J.6
Superti-Furga, G.7
-
17
-
-
0344626926
-
Structural basis for the autoinhibition of c-Abl tyrosine kinase
-
DOI 10.1016/S0092-8674(03)00194-6
-
Nagar B, Hantschel O, Young MA et al (2003) Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell 112:859-871. doi:10.1016/S0092- 8674(03)00194-6 (Pubitemid 36378887)
-
(2003)
Cell
, vol.112
, Issue.6
, pp. 859-871
-
-
Nagar, B.1
Hantschel, O.2
Young, M.A.3
Scheffzek, K.4
Veach, D.5
Bornmann, W.6
Clarkson, B.7
Superti-Furga, G.8
Kuriyan, J.9
-
18
-
-
0347132269
-
Regulation of the c-Abl and Bcr-Abl tyrosine kinases
-
DOI 10.1038/nrm1280
-
Hantschel O, Superti-Furga G (2004) Regulation of the c-Abl and Bcr-Abl tyrosine kinases. Nat Rev Mol Cell Biol 5:33-44. doi: 10.1038/nrm1280 (Pubitemid 38089839)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.1
, pp. 33-44
-
-
Hantschel, O.1
Superti-Furga, G.2
-
19
-
-
0034821283
-
Hydrogen peroxide stimulates apoptosis in cultured human retinal pigment epithelial cells
-
DOI 10.1076/ceyr.22.3.165.5517
-
Jin GF, Hurst JS, Godley BF (2001) Hydrogen peroxide stimulates apoptosis in cultured human retinal pigment epithelial cells. Curr Eye Res 22:165-173. doi:10.1076/ceyr.22.3.165.5517 (Pubitemid 32881422)
-
(2001)
Current Eye Research
, vol.22
, Issue.3
, pp. 165-173
-
-
Jin, G.-F.1
Hurst, J.S.2
Godley, B.F.3
-
20
-
-
0032438618
-
The topoisomerase I inhibitors, camptothecin and β-lapachone, induce apoptosis of human retinal pigment epithelial cells
-
DOI 10.1006/exer.1998.0544
-
Hueber A, Esser P, Heimann K et al (1998) The topoisomerase I inhibitors, camptothecin and beta-lapachone, induce apoptosis of human retinal pigment epithelial cells. Exp Eye Res 67:525-530. doi:10.1006/exer.1998.0544 (Pubitemid 29005149)
-
(1998)
Experimental Eye Research
, vol.67
, Issue.5
, pp. 525-530
-
-
Hueber, A.1
Esser, P.2
Heimann, K.3
Kociok, N.4
Winter, S.5
Weller, M.6
-
21
-
-
18144408056
-
C-Abl as a modulator of p53
-
DOI 10.1016/j.bbrc.2005.03.152, Apoptosis Control
-
Levav-Cohen Y, Goldberg Z, Zuckerman V et al (2005) C-Abl as a modulator of p53. Biochem Biophys Res Commun 331:737-749. doi:10.1016/j.bbrc.2005.03.152 (Pubitemid 40615505)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.331
, Issue.3
, pp. 737-749
-
-
Levav-Cohen, Y.1
Goldberg, Z.2
Zuckerman, V.3
Grossman, T.4
Haupt, S.5
Haupt, Y.6
-
22
-
-
0029959878
-
Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53
-
DOI 10.1074/jbc.271.43.26457
-
Yuan ZM, Huang Y, Fan MM et al (1996) Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53. J Biol Chem 271:26457-26460. doi: 10.1074/jbc.271.43.26457 (Pubitemid 26359039)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.43
, pp. 26457-26460
-
-
Yuan, Z.-M.1
Huang, Y.2
Fan, M.-M.3
Sawyers, C.4
Kharbanda, S.5
Kufe, D.6
-
23
-
-
0031020908
-
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase
-
DOI 10.1073/pnas.94.4.1437
-
Yuan ZM, Huang Y, Ishiko T et al (1997) Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci USA 94:1437-1440. doi:10.1073/pnas.94.4.1437 (Pubitemid 27087869)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.4
, pp. 1437-1440
-
-
Yuan, Z.-M.1
Huang, Y.2
Ishiko, T.3
Kharbanda, S.4
Weichselbaum, R.5
Kufe, D.6
-
24
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
doi:10.1016/0092-8674(95)90513-8
-
Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299. doi:10.1016/0092-8674(95)90513-8
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
25
-
-
0035914432
-
Caffeine sensitizes human h358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of bax protein
-
doi:10.1074/jbc.M102683200
-
Dubrez L, Coll JL, HurbinAet al (2001) Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein. J Biol Chem 276:38980-38987. doi:10.1074/jbc.M102683200
-
(2001)
J Biol Chem
, vol.276
, pp. 38980-38987
-
-
Dubrez, L.1
Coll, J.L.2
Hurbin, A.3
-
26
-
-
0035889959
-
Selective activation of p38 mitogen-activated protein kinase cascade in human neutrophils stimulated by IL-1β
-
Suzuki K, Hino M, Kutsuna H et al (2001) Selective activation of p38 mitogen-activated protein kinase cascade in human neutrophils stimulated by IL-1beta. J Immunol 167:5940-5947 (Pubitemid 33062790)
-
(2001)
Journal of Immunology
, vol.167
, Issue.10
, pp. 5940-5947
-
-
Suzuki, K.1
Hino, M.2
Kutsuna, H.3
Hato, F.4
Sakamoto, C.5
Takahashi, T.6
Tatsumi, N.7
Kitagawa, S.8
-
27
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869 (Pubitemid 32267078)
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
28
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
DOI 10.1210/er.22.2.153
-
Pearson G, Robinson F, Beers GT et al (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22:153-183. doi:10.1210/er.22.2.153 (Pubitemid 32458157)
-
(2001)
Endocrine Reviews
, vol.22
, Issue.2
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.B.3
Xu, B.-E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
29
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
DOI 10.1128/MMBR.68.2.320-344.2004
-
Roux PP, Blenis J (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68:320-344. doi:10.1128/ MMBR.68.2.320-344.2004 (Pubitemid 38756868)
-
(2004)
Microbiology and Molecular Biology Reviews
, vol.68
, Issue.2
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
30
-
-
0035413618
-
MAP kinases
-
DOI 10.1021/cr000241p
-
Chen Z, Gibson TB, Robinson F et al (2001) MAP kinases. Chem Rev 101:2449-2476. doi:10.1021/cr000241p (Pubitemid 35373029)
-
(2001)
Chemical Reviews
, vol.101
, Issue.8
, pp. 2449-2476
-
-
Chen, Z.1
Gibson, T.B.2
Robinson, F.3
Silvestro, L.4
Pearson, G.5
Xu, B.-E.6
Wright, A.7
Vanderbilt, C.8
Cobb, M.H.9
-
31
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs L et al (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811. doi:10.1126/science.7914033 (Pubitemid 24266145)
-
(1994)
Science
, vol.265
, Issue.5173
, pp. 808-811
-
-
Man, J.1
Lee, J.-D.2
Bibbs, L.3
Ulevitch, R.J.4
-
32
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
DOI 10.1016/0092-8674(94)90380-8
-
Derijard B, Hibi M, Wu IH et al (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037. doi:10.1016/ 0092-8674(94)90380-8 (Pubitemid 24106383)
-
(1994)
Cell
, vol.76
, Issue.6
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.-H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
33
-
-
0030922083
-
A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion
-
DOI 10.1074/jbc.272.26.16657
-
Mizukami Y, Yoshioka K, Morimoto S et al (1997) A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion. J Biol Chem 272:16657-16662. doi:10.1074/jbc.272.26.16657 (Pubitemid 27276499)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.26
, pp. 16657-16662
-
-
Mizukami, Y.1
Yoshioka, K.2
Morimoto, S.3
Yoshida, K.-I.4
-
34
-
-
0030922032
-
Mitogen-activated protein kinase translocates to the nucleus during ischaemia and is activated during reperfusion
-
Mizukami Y, Yoshida K (1997) Mitogen-activated protein kinase translocates to the nucleus during ischaemia and is activated during reperfusion. Biochem J 323(Pt 3):785-790 (Pubitemid 27202350)
-
(1997)
Biochemical Journal
, vol.323
, Issue.3
, pp. 785-790
-
-
Mizukami, Y.1
Yoshida, K.-I.2
-
35
-
-
31044455375
-
JNK and ERK MAP kinases mediate induction of IL-1β, TNF-α and IL-8 following hyperosmolar stress in human limbal epithelial cells
-
DOI 10.1016/j.exer.2005.08.019, PII S0014483505002654
-
Li DQ, Luo L, Chen Z et al (2006) JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res 82:588-596. doi:10.1016/j.exer.2005.08.019 (Pubitemid 43122089)
-
(2006)
Experimental Eye Research
, vol.82
, Issue.4
, pp. 588-596
-
-
Li, D.-Q.1
Luo, L.2
Chen, Z.3
Kim, H.-S.4
Song, X.J.5
Pflugfelder, S.C.6
-
36
-
-
0032710514
-
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
-
Sparrow JR, Parish CA, Hashimoto M et al (1999) A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. Invest Ophthalmol Vis Sci 40:2988-2995 (Pubitemid 29521615)
-
(1999)
Investigative Ophthalmology and Visual Science
, vol.40
, Issue.12
, pp. 2988-2995
-
-
Sparrow, J.R.1
Parish, C.A.2
Hashimoto, M.3
Nakanishi, K.4
-
37
-
-
0034086115
-
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
-
Sparrow JR, Nakanishi K, Parish CA (2000) The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci 41:1981-1989 (Pubitemid 30354376)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.7
, pp. 1981-1989
-
-
Sparrow, J.R.1
Nakanishi, K.2
Parish, C.A.3
-
38
-
-
0032438193
-
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
-
DOI 10.1073/pnas.95.25.14609
-
Parish CA, Hashimoto M, Nakanishi K et al (1998) Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proc Natl Acad Sci USA 95:14609-14613. doi:10.1073/pnas.95.25.14609 (Pubitemid 29003678)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14609-14613
-
-
Parish, C.A.1
Hashimoto, M.2
Nakanishi, K.3
Dillon, J.4
Sparrow, J.5
-
39
-
-
4544343214
-
A Bcr/Abl-independent, lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2
-
DOI 10.1074/jbc.M402290200
-
Dai Y, Rahmani M, Corey SJ et al (2004) A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2. J Biol Chem 279:34227-34239. doi:10.1074/jbc. M402290200 (Pubitemid 39318046)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34227-34239
-
-
Dai, Y.1
Rahmani, M.2
Corey, S.J.3
Dent, P.4
Grant, S.5
-
40
-
-
3042631208
-
Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression
-
DOI 10.1167/iovs.03-0608
-
Bian ZM, Elner SG, Yoshida A et al (2004) Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression. Invest Ophthalmol Vis Sci 45:1887-1896. JID-7703701 (Pubitemid 38868986)
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, Issue.6
, pp. 1887-1896
-
-
Bian, Z.-M.1
Elner, S.G.2
Yoshida, A.3
Elner, V.M.4
-
41
-
-
0034714334
-
P38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide
-
doi:10.1074/jbc.M001185200
-
Zhuang S, Demirs JT, Kochevar IE (2000) p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem 275:25939-25948. doi:10.1074/jbc.M001185200
-
(2000)
J Biol Chem
, vol.275
, pp. 25939-25948
-
-
Zhuang, S.1
Demirs, J.T.2
Kochevar, I.E.3
-
42
-
-
33744982638
-
Indirect antioxidant protection against photooxidative processes initiated in retinal pigment epithelial cells by a lipofuscin pigment
-
DOI 10.1089/rej.2006.9.256
-
Zhou J, Gao X, Cai B et al (2006) Indirect antioxidant protection against photooxidative processes initiated in retinal pigment epithelial cells by a lipofuscin pigment. Rejuvenation Res 9:256-263. doi:10.1089/rej.2006.9.256 (Pubitemid 43862456)
-
(2006)
Rejuvenation Research
, vol.9
, Issue.2
, pp. 256-263
-
-
Zhou, J.1
Gao, X.2
Cai, B.3
Sparrow, J.R.4
-
43
-
-
0035496905
-
Interleukin-5 inhibits translocation of bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils
-
doi:10.1182/blood.V98.7.2239
-
Dewson G, Cohen GM, Wardlaw AJ (2001) Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils. Blood 98:2239-2247. doi:10.1182/blood.V98.7. 2239
-
(2001)
Blood
, vol.98
, pp. 2239-2247
-
-
Dewson, G.1
Cohen, G.M.2
Wardlaw, A.J.3
-
44
-
-
0034948677
-
Myc potentiates apoptosis by stimulating bax activity at the mitochondria
-
DOI 10.1128/MCB.21.14.4725-4736.2001
-
Soucie EL, Annis MG, Sedivy J et al (2001) Myc potentiates apoptosis by stimulating Bax activity at the mitochondria. Mol Cell Biol 21:4725-4736. doi:10.1128/MCB.21.14.4725-4736.2001 (Pubitemid 32588253)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.14
, pp. 4725-4736
-
-
Soucie, E.L.1
Annis, M.G.2
Sedivy, J.3
Filmus, J.4
Leber, B.5
Andrews, D.W.6
Penn, L.Z.7
-
45
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
DOI 10.1073/pnas.95.9.4997
-
Jurgensmeier JM, Xie Z, Deveraux Q et al (1998) Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA 95:4997-5002. doi:10.1073/pnas.95.9.4997 (Pubitemid 28208539)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.9
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
Ellerby, L.4
Bredesen, D.5
Reed, J.C.6
-
46
-
-
0036754607
-
MItogen-activated protein kinases and their role in regulation of cellular processes
-
Strniskova M, Barancik M, Ravingerova T (2002) Mitogenactivated protein kinases and their role in regulation of cellular processes. Gen Physiol Biophys 21:231-255. JID-8400604 (Pubitemid 35282663)
-
(2002)
General Physiology and Biophysics
, vol.21
, Issue.3
, pp. 231-255
-
-
Strniskova, M.1
Barancik, M.2
Ravingerova, T.3
-
47
-
-
0042734434
-
The true face of jnk activation in apoptosis
-
doi:10.1046/j.1474-9728.2002. 00014.x
-
Lin A, Dibling B (2002) The true face of JNK activation in apoptosis. Aging Cell 1:112-116. doi:10.1046/j.1474-9728.2002. 00014.x
-
(2002)
Aging Cell
, vol.1
, pp. 112-116
-
-
Lin, A.1
Dibling, B.2
-
48
-
-
0000117096
-
Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin
-
Schutt F, Davies S, Kopitz J et al (2000) Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci 41:2303-2308 (Pubitemid 30451007)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.8
, pp. 2303-2308
-
-
Schutt, F.1
Davies, S.2
Kopitz, J.3
Holz, F.G.4
Boulton, M.E.5
-
49
-
-
14744301343
-
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
-
DOI 10.1038/ncb1228
-
Yoshida K, Yamaguchi T, Natsume T et al (2005) JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c- Abl in the apoptotic response to DNA damage. Nat Cell Biol 7:278-285. doi:10.1038/ncb1228 (Pubitemid 40331129)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.3
, pp. 278-285
-
-
Yoshida, K.1
Yamaguchi, T.2
Natsume, T.3
Kufe, D.4
Miki, Y.5
-
50
-
-
0029098225
-
Activation of the c- abl tyrosine kinase in the stress response to dna-damaging agents
-
doi:10.1038/376785a0
-
Kharbanda S, Ren R, Pandey P et al (1995) Activation of the c- Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature 376:785-788. doi:10.1038/376785a0
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandey, P.3
-
51
-
-
0032443366
-
Determination of cell fate by c-Abl activation in the response to DNA damage
-
Kharbanda S, Yuan ZM, Weichselbaum R et al (1998) Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene 17:3309-3318. JID-8711562 (Pubitemid 29043983)
-
(1998)
Oncogene
, vol.17
, Issue.25
, pp. 3309-3318
-
-
Kharbanda, S.1
Yuan, Z.-M.2
Weichselbaum, R.3
Kufe, D.4
-
52
-
-
25444480231
-
C-Abl in oxidative stress, aging and cancer
-
Li B (2005) c-Abl in oxidative stress, aging and cancer. Cell Cycle 4:246-248 (Pubitemid 41365327)
-
(2005)
Cell Cycle
, vol.4
, Issue.2
, pp. 246-248
-
-
Li, B.1
-
53
-
-
15744398903
-
C-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage
-
DOI 10.1074/jbc.M413787200
-
Raina D, Pandey P, Ahmad R et al (2005) c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem 280:11147-11151. doi: 10.1074/jbc.M413787200 (Pubitemid 40418421)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.12
, pp. 11147-11151
-
-
Raina, D.1
Pandey, P.2
Ahmad, R.3
Bharti, A.4
Ren, J.5
Kharbanda, S.6
Weichselbaum, R.7
Kufe, D.8
-
54
-
-
19644387170
-
Role of c-Abl in the DNA damage stress response
-
DOI 10.1038/sj.cr.7290261
-
Shaul Y, Ben-Yehoyada M (2005) Role of c-Abl in the DNA damage stress response. Cell Res 15:33-35. doi:10.1038/sj.cr.72 90261 (Pubitemid 41653962)
-
(2005)
Cell Research
, vol.15
, Issue.1
, pp. 33-35
-
-
Shaul, Y.1
Ben-Yehoyada, M.2
-
55
-
-
0036365079
-
Bax and bh3-domain-only proteins in p53-mediated apoptosis
-
doi: 10.2741/wu1
-
Wu X, Deng Y (2002) Bax and BH3-domain-only proteins in p53-mediated apoptosis. Front Biosci 7:d151-d156. doi: 10.2741/wu1
-
(2002)
Front Biosci
, vol.7
-
-
Wu, X.1
Deng, Y.2
-
56
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
DOI 10.1016/S1097-2765(01)00214-3
-
Nakano K, Vousden KH (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7:683-694. JID-9802571 (Pubitemid 32706359)
-
(2001)
Molecular Cell
, vol.7
, Issue.3
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
57
-
-
33750622313
-
Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells
-
DOI 10.1007/s10495-006-9403-6
-
Ho TC, Yang YC, Cheng HC et al (2006) Activation of mitogenactivated protein kinases is essential for hydrogen peroxideinduced apoptosis in retinal pigment epithelial cells. Apoptosis 11:1899-1908. doi:10.1007/s10495-006-9403-6 (Pubitemid 44691574)
-
(2006)
Apoptosis
, vol.11
, Issue.11
, pp. 1899-1908
-
-
Ho, T.-C.1
Yang, Y.-C.2
Cheng, H.-C.3
Wu, A.-C.4
Chen, S.-L.5
Chen, H.-K.6
Tsao, Y.-P.7
-
58
-
-
34247141914
-
2 by augmenting GSH and activating MAPK
-
DOI 10.1167/iovs.06-0318
-
Qin S, McLaughlin AP, De Vries GW (2006) Protection of RPE cells from oxidative injury by 15-deoxy-delta12, 14-prostaglandin J2 by augmenting GSH and activating MAPK. Invest Ophthalmol Vis Sci 47:5098-5105. doi:10.1167/iovs.06- 0318 (Pubitemid 46586417)
-
(2006)
Investigative Ophthalmology and Visual Science
, vol.47
, Issue.11
, pp. 5098-5105
-
-
Qin, S.1
McLaughlin, A.P.2
De Vries, G.W.3
-
59
-
-
0345257178
-
Transforming growth factor-β induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: Involvement of mitogen-activated protein kinases
-
DOI 10.1002/jcp.10378
-
Nagineni CN, Samuel W, Nagineni S et al (2003) Transforming growth factor-beta induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: involvement of mitogen-activated protein kinases. J Cell Physiol 197:453-462. doi:10.1002/jcp.10378 (Pubitemid 37487044)
-
(2003)
Journal of Cellular Physiology
, vol.197
, Issue.3
, pp. 453-462
-
-
Nagineni, C.N.1
Samuel, W.2
Nagineni, S.3
Pardhasaradhi, K.4
Wiggert, B.5
Detrick, B.6
Hooks, J.J.7
-
60
-
-
0242552020
-
P38 Mitogen-Activated Protein Kinase Is Crucially Involved in Osteoclast Differentiation but Not in Cytokine Production, Phagocytosis, or Dendritic Cell Differentiation of Bone Marrow Macrophages
-
DOI 10.1210/en.2003-0166
-
Li X, Udagawa N, Takami M et al (2003) p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages. Endocrinology 144:4999-5005. doi:10.1210/en.2003-0166 (Pubitemid 37378415)
-
(2003)
Endocrinology
, vol.144
, Issue.11
, pp. 4999-5005
-
-
Li, X.1
Udagawa, N.2
Takami, M.3
Sato, N.4
Kobayashi, Y.5
Takahashi, N.6
-
61
-
-
0037082111
-
Role of p38 mitogen-activated protein kinase in the 4-hydroxy-2-nonenal- induced cyclooxygenase-2 expression
-
DOI 10.1006/abbi.2001.2601
-
Kumagai T, Nakamura Y, Osawa T et al (2002) Role of p38 mitogen-activated protein kinase in the 4-hydroxy-2-nonenalinduced cyclooxygenase-2 expression. Arch Biochem Biophys 397:240-245. doi:10.1006/abbi.2001.2601 (Pubitemid 34852286)
-
(2002)
Archives of Biochemistry and Biophysics
, vol.397
, Issue.2
, pp. 240-245
-
-
Kumagai, T.1
Nakamura, Y.2
Osawa, T.3
Uchida, K.4
-
62
-
-
0033605576
-
C-Abl neutralizes the inhibitory effect of Mdm2 on p53
-
DOI 10.1074/jbc.274.13.8371
-
Sionov RV, Moallem E, Berger M et al (1999) c-Abl neutralizes the inhibitory effect of Mdm2 on p53. J Biol Chem 274:8371-8374. doi:10.1074/jbc.274.13.8371 (Pubitemid 29164623)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.13
, pp. 8371-8374
-
-
Sionov, R.V.1
Moallem, E.2
Berger, M.3
Kazaz, A.4
Gerlitz, O.5
Ben-Neriah, Y.6
Oren, M.7
Haupt, Y.8
-
63
-
-
0034898859
-
C-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination
-
DOI 10.1128/MCB.21.17.5869-5878.2001
-
Sionov RV, Coen S, Goldberg Z et al (2001) c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination. Mol Cell Biol 21:5869-5878. doi:10.1128/MCB.21.17.5869-5878.2001 (Pubitemid 32737804)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.17
, pp. 5869-5878
-
-
Vogt Sionov, R.1
Coen, S.2
Goldberg, Z.3
Berger, M.4
Bercovich, B.5
Ben-Neriah, Y.6
Ciechanover, A.7
Haupt, Y.8
|