Rod and cone degeneration in the rd mouse is p53 independent

Molecular Vision

Volumn 7, Issue , 2001, Pages 101-106

  Wu, Jie ^a,b   Trogadis, Judy ^a,b   Bremmer, Rod ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PEANUT AGGLUTININ; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CELL KINETICS; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; MEDICAL ASSESSMENT; MOUSE; MOUSE STRAIN; MUELLER CELL; NICK END LABELING; NONHUMAN; PERINATAL PERIOD; PHOTORECEPTOR CELL; PROTEIN DEFICIENCY; PROTEIN LOCALIZATION; RETINA BIPOLAR GANGLION CELL; RETINA CONE; RETINA DEGENERATION; RETINA DEVELOPMENT; RETINA ROD; RETINITIS PIGMENTOSA;

ANIMALS; APOPTOSIS; CELL COUNT; CELL SURVIVAL; DNA PRIMERS; GENOTYPE; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PEANUT AGGLUTININ; PHOTORECEPTORS, VERTEBRATE; RETINA; RETINITIS PIGMENTOSA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035789540     PISSN: 10900535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Phelan JK, Bok D. A brief review of retinitis pigmentosa and the identified retinitis pigmentosa genes. Mol Vis 2000; 6:116-24 .
2. van Soest S, Westerveld A, de Jong PT, Bleeker-Wagemakers EM, Bergen AA. Retinitis pigmentosa: defined from a molecular point of view. Surv Ophthalmol 1999; 43:321-34.
3. Pittler SJ, Baehr W. Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse. Proc Natl Acad Sci U S A 1991; 88:8322-6.
4. Bowes C, Li T, Frankel WN, Danciger M, Coffin JM, Applebury ML, Farber DB. Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. Proc Natl Acad Sci U S A 1993; 90:2955-9.
5. Carter-Dawson LD, La Vail MM, Sidman RL. Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci 1978; 17:489-98.
6. Jimenez AJ, Garcia-Fernandez JM, Gonzalez B, Foster RG. The spatio-temporal pattern of photoreceptor degeneration in the aged rd/rd mouse retina. Cell Tissue Res 1996; 284:193-202.
7. La Vail MM, Matthes MT, Yasumura D, Steinberg RH. Variability in rate of cone degeneration in the retinal degeneration (rd/rd) mouse. Exp Eye Res 1997; 65:45-50.
8. Ogilvie JM, Tenkova T, Lett JM, Speck J, Landgraf M, Silverman MS. Age-related distribution of cones and ON-bipolar cells in the rd mouse retina. Curr Eye Res 1997; 16:244-51.
9. Chang GQ, Hao Y, Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 1993; 11:595-605.
10. Portera-Cailliau C, Sung CH, Nathans J, Adler R. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci U S A 1994; 91:974-8.
11. Lolley RN, Rong H, Craft CM. Linkage of photoreceptor degeneration by apoptosis with inherited defect in phototransduction. Invest Ophthalmol Vis Sci 1994; 35:358-62.
12. Chen J, Flannery JG, La Vail MM, Steinberg RH, Xu J, Simon MI. bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proc Natl Acad Sci U S A 1996; 93:7042-7.
13. Joseph RM, Li T. Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration. Invest Ophthalmol Vis Sci 1996; 37:2434-46.
14. Tsang SH, Chen J, Kjeldbye H, Li WS, Simon MI, Gouras P, Goff SP. Retarding photoreceptor degeneration in Pdegtm1/Pdegtml mice by an apoptosis suppressor gene. Invest Ophthalmol Vis Sci 1997; 38:943-50.
15. Ali RR, Reichel MB, Kanuga N, Munro PM, Alexander RA, Clarke AR, Luthert PJ, Bhattacharya SS, Hunt DM. Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse. Curr Eye Res 1998; 17:917-23.
16. Hafezi F, Abegg M, Grimm C, Wenzel A, Munz K, Sturmer J, Farber DB, Reme CE. Retinal degeneration in the rd mouse in the absence of c-fos. Invest Ophthalmol Vis Sci 1998; 39:2239-44.
17. Mosinger Ogilvie J, Deckwerth TL, Knudson CM, Korsmeyer SJ. Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice [published erratum appears in Invest Ophthalmol Vis Sci 1998; 39:2244]. Invest Ophthalmol Vis Sci 1998; 39:1713-20.
18. Nir I, Kedzierski W, Chen J, Travis GH. Expression of Bcl-2 protects against photoreceptor degeneration in retinal degeneration slow (rds) mice. J Neurosci 2000; 20:2150-4.
19. Sheikh MS, Fornace AJ Jr. Role of p53 family members in apoptosis. J Cell Physiol 2000; 182:171-81.
20. Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 1995; 10:175-80.
21. Armstrong JF, Kaufman MH, Harrison DJ, Clarke AR. High-frequency developmental abnormalities in p53-deficient mice. Curr Biol 1995; 5:931-6.
22. Pan H, Griep AE. Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev 1995; 9:2157-69.
23. Reichel MB, Ali RR, D'Esposito F, Clarke AR, Luthert PJ, Bhattacharya SS, Hunt DM. High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. Cell Death Differ 1998; 5:156-62.
24. Herzog KH, Chong MJ, Kapsetaki M, Morgan JI, McKinnon PJ. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 1998; 280:1089-91.
25. Mills MD, Windle JJ, Albert DM. Retinoblastoma in transgenic mice: models of hereditary retinoblastoma. Surv Ophthalmol 1999; 43:508-18.
26. Hopp RM, Ransom N, Hilsenbeck SG, Papermaster DS, Windle JJ. Apoptosis in the murine rd1 retinal degeneration is predominantly p53-independent. Mol Vis 1998; 4:5 .
27. Jacks T, Remington L, Williams BO, Scmitt EM, Halachmi S, Bronson RT, Weinberg RA. Tumor spectrum analysis in p53-mutant mice. Curr Biol 1994; 4:1-7.
28. Blanks JC, Johnson LV. Specific binding of peanut lectin to a class of retinal photoreceptor cells. A species comparison. Invest Ophthalmol Vis Sci 1984; 25:546-57.
29. Young RW. Cell death during differentiation of the retina in the mouse. J Comp Neurol 1984; 229:362-73.
30. Garcia-Fernandez JM, Jimenez AJ, Foster RG. The persistence of cone photoreceptors within the dorsal retina of aged retinally degenerate mice (rd/rd): implications for circadian organization. Neurosci Lett 1995; 187:33-6.