Inhibition of Mdm2 sensitizes human retinal pigment epithelial cells to apoptosis

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 6, 2011, Pages 3368-3380

  Bhattacharya, Sujoy ^a   Ray, Ramesh M ^a   Chaum, Edward ^a   Johnson, Dianna A ^a   Johnson, Leonard R ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE INHIBITOR 1; NUTLIN 3; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN NOXA; PROTEIN P53; PUMA PROTEIN; SMALL INTERFERING RNA; BCL2L1 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; MDM2 PROTEIN, HUMAN; PIPERAZINE DERIVATIVE; PROTEIN BCL X;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; PATHOLOGY;

ADULT; APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL LINE; CELL PROLIFERATION; DNA FRAGMENTATION; HUMANS; IMIDAZOLES; PIPERAZINES; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; RETINAL PIGMENT EPITHELIUM; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79960981176     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6991     Document Type: Article

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