Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Nishiyama, Akira ^a,b,c   Dey, Anup ^a   Tamura, Tomohiko ^b   Ko, Minoru ^c   Ozato, Keiko ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CELL PROTEIN; JANUS KINASE; JANUS KINASE INHIBITOR; NOCODAZOLE; PROTEIN BRD4; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; BRD4 PROTEIN, MOUSE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL DIVISION; CELL PROTECTION; CELL STRESS; CHROMOSOME; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; MITOSIS; MITOSIS INHIBITION; MOUSE; NONHUMAN; PROTEIN SECRETION; ANIMAL; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; MOUSE MUTANT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHROMOSOMES; IMMUNOBLOTTING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, MUTANT STRAINS; MITOSIS; NOCODAZOLE; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84860431094     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034719     Document Type: Article

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