메뉴 건너뛰기




Volumn 235, Issue 2, 2012, Pages 427-435

Converging miRNA functions in diverse brain disorders: A case for miR-124 and miR-126

Author keywords

Brain diseases; Cancer; CNS disorders; MiR 124; MiR 126; MiRNAs; Neurodegeneration; Psychiatric; Signaling pathways; Tumor

Indexed keywords

MICRORNA; MICRORNA 124; MICRORNA 126;

EID: 84860387540     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.11.035     Document Type: Review
Times cited : (85)

References (139)
  • 1
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • 2008. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 5
    • 70349247841 scopus 로고    scopus 로고
    • Searching for MIND: microRNAs in neurodegenerative diseases
    • Barbato C., Ruberti F., Cogoni C. Searching for MIND: microRNAs in neurodegenerative diseases. J. Biomed. Biotechnol. 2009, 2009:871313.
    • (2009) J. Biomed. Biotechnol. , vol.2009 , pp. 871313
    • Barbato, C.1    Ruberti, F.2    Cogoni, C.3
  • 8
    • 77953564662 scopus 로고    scopus 로고
    • EGFL7: a new player in homeostasis of the nervous system
    • Bicker F., Schmidt M.H. EGFL7: a new player in homeostasis of the nervous system. Cell Cycle 2010, 9:1263-1269.
    • (2010) Cell Cycle , vol.9 , pp. 1263-1269
    • Bicker, F.1    Schmidt, M.H.2
  • 9
    • 77950229880 scopus 로고    scopus 로고
    • Neural mechanisms of ageing and cognitive decline
    • Bishop N.A., Lu T., Yankner B.A. Neural mechanisms of ageing and cognitive decline. Nature 2010, 464:529-535.
    • (2010) Nature , vol.464 , pp. 529-535
    • Bishop, N.A.1    Lu, T.2    Yankner, B.A.3
  • 12
    • 33947180884 scopus 로고    scopus 로고
    • A functional study of miR-124 in the developing neural tube
    • Cao X., Pfaff S.L., Gage F.H. A functional study of miR-124 in the developing neural tube. Genes Dev. 2007, 21:531-536.
    • (2007) Genes Dev. , vol.21 , pp. 531-536
    • Cao, X.1    Pfaff, S.L.2    Gage, F.H.3
  • 13
    • 70449530430 scopus 로고    scopus 로고
    • MicroRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity
    • Chandrasekar V., Dreyer J.L. microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity. Mol. Cell. Neurosci. 2009, 42:350-362.
    • (2009) Mol. Cell. Neurosci. , vol.42 , pp. 350-362
    • Chandrasekar, V.1    Dreyer, J.L.2
  • 14
    • 79954588293 scopus 로고    scopus 로고
    • Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference
    • Chandrasekar V., Dreyer J.L. Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference. Neuropsychopharmacology 2011, 36:1149-1164.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1149-1164
    • Chandrasekar, V.1    Dreyer, J.L.2
  • 15
    • 63649138643 scopus 로고    scopus 로고
    • MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • Cheng L.C., Pastrana E., Tavazoie M., Doetsch F. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 2009, 12:399-408.
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, F.4
  • 16
    • 67749110060 scopus 로고    scopus 로고
    • Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines
    • Cheung H.C., Hai T., Zhu W., Baggerly K.A., Tsavachidis S., Krahe R., Cote G.J. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain 2009, 132:2277-2288.
    • (2009) Brain , vol.132 , pp. 2277-2288
    • Cheung, H.C.1    Hai, T.2    Zhu, W.3    Baggerly, K.A.4    Tsavachidis, S.5    Krahe, R.6    Cote, G.J.7
  • 17
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi S.W., Zang J.B., Mele A., Darnell R.B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009, 460:479-486.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 19
    • 77954394167 scopus 로고    scopus 로고
    • The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
    • Clark A.M., Goldstein L.D., Tevlin M., Tavare S., Shaham S., Miska E.A. The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans. Nucleic Acids Res. 2010, 38:3780-3793.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 3780-3793
    • Clark, A.M.1    Goldstein, L.D.2    Tevlin, M.3    Tavare, S.4    Shaham, S.5    Miska, E.A.6
  • 21
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco C., Otto S., Han J.J., Mandel G. Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2422-2427.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Mandel, G.4
  • 22
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney D.C., Flesken-Nikitin A., Godwin A.K., Wang W., Nikitin A.Y. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 2007, 67:8433-8438.
    • (2007) Cancer Res. , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 23
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: shared and specific mechanisms
    • Craft S., Watson G.S. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol. 2004, 3:169-178.
    • (2004) Lancet Neurol. , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 25
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • Deo M., Yu J.Y., Chung K.H., Tippens M., Turner D.L. Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn. 2006, 235:2538-2548.
    • (2006) Dev. Dyn. , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3    Tippens, M.4    Turner, D.L.5
  • 26
    • 79958237903 scopus 로고    scopus 로고
    • Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation
    • Du L., Pertsemlidis A. Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation. J. Mol. Cell Biol. 2011, 3:176-180.
    • (2011) J. Mol. Cell Biol. , vol.3 , pp. 176-180
    • Du, L.1    Pertsemlidis, A.2
  • 31
    • 62349138052 scopus 로고    scopus 로고
    • MicroRNAs: opening a new vein in angiogenesis research
    • Fish J.E., Srivastava D. MicroRNAs: opening a new vein in angiogenesis research. Sci. Signal. 2009, 2:pe1.
    • (2009) Sci. Signal. , vol.2
    • Fish, J.E.1    Srivastava, D.2
  • 34
    • 67149139990 scopus 로고    scopus 로고
    • The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease
    • Freude S., Schilbach K., Schubert M. The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease. Curr. Alzheimer Res. 2009, 6:213-223.
    • (2009) Curr. Alzheimer Res. , vol.6 , pp. 213-223
    • Freude, S.1    Schilbach, K.2    Schubert, M.3
  • 35
    • 77952299722 scopus 로고    scopus 로고
    • MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
    • Furuta M., Kozaki K.I., Tanaka S., Arii S., Imoto I., Inazawa J. miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 2010, 31:766-776.
    • (2010) Carcinogenesis , vol.31 , pp. 766-776
    • Furuta, M.1    Kozaki, K.I.2    Tanaka, S.3    Arii, S.4    Imoto, I.5    Inazawa, J.6
  • 36
    • 80655134727 scopus 로고    scopus 로고
    • Context effect: microRNA-10b in cancer cell proliferation, spread and death
    • Gabriely G., Teplyuk N.M., Krichevsky A.M. Context effect: microRNA-10b in cancer cell proliferation, spread and death. Autophagy 2011, 7.
    • (2011) Autophagy , vol.7
    • Gabriely, G.1    Teplyuk, N.M.2    Krichevsky, A.M.3
  • 37
    • 77957194193 scopus 로고    scopus 로고
    • Context-dependent functions of specific microRNAs in neuronal development
    • Gao F.B. Context-dependent functions of specific microRNAs in neuronal development. Neural Dev. 2010, 5:25.
    • (2010) Neural Dev. , vol.5 , pp. 25
    • Gao, F.B.1
  • 38
    • 79956032718 scopus 로고    scopus 로고
    • Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
    • Gaughwin P.M., Ciesla M., Lahiri N., Tabrizi S.J., Brundin P., Bjorkqvist M. Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease. Hum. Mol. Genet. 2011, 20:2225-2237.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 2225-2237
    • Gaughwin, P.M.1    Ciesla, M.2    Lahiri, N.3    Tabrizi, S.J.4    Brundin, P.5    Bjorkqvist, M.6
  • 42
    • 0034708539 scopus 로고    scopus 로고
    • N-terminal tripeptide of IGF-1 (GPE) prevents the loss of TH positive neurons after 6-OHDA induced nigral lesion in rats
    • Guan J., Krishnamurthi R., Waldvogel H.J., Faull R.L., Clark R., Gluckman P. N-terminal tripeptide of IGF-1 (GPE) prevents the loss of TH positive neurons after 6-OHDA induced nigral lesion in rats. Brain Res. 2000, 859:286-292.
    • (2000) Brain Res. , vol.859 , pp. 286-292
    • Guan, J.1    Krishnamurthi, R.2    Waldvogel, H.J.3    Faull, R.L.4    Clark, R.5    Gluckman, P.6
  • 43
    • 52249096359 scopus 로고    scopus 로고
    • The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
    • Guo C., Sah J.F., Beard L., Willson J.K., Markowitz S.D., Guda K. The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 2008, 47:939-946.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 939-946
    • Guo, C.1    Sah, J.F.2    Beard, L.3    Willson, J.K.4    Markowitz, S.D.5    Guda, K.6
  • 44
    • 71049188566 scopus 로고    scopus 로고
    • Haplotype distribution and evolutionary pattern of miR-17 and miR-124 families based on population analysis
    • Guo L., Sun B., Sang F., Wang W., Lu Z. Haplotype distribution and evolutionary pattern of miR-17 and miR-124 families based on population analysis. PLoS One 2009, 4:e7944.
    • (2009) PLoS One , vol.4
    • Guo, L.1    Sun, B.2    Sang, F.3    Wang, W.4    Lu, Z.5
  • 45
    • 77949426688 scopus 로고    scopus 로고
    • A novel microRNA and transcription factor mediated regulatory network in schizophrenia
    • Guo A.Y., Sun J., Jia P., Zhao Z. A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC Syst. Biol. 2010, 4:10.
    • (2010) BMC Syst. Biol. , vol.4 , pp. 10
    • Guo, A.Y.1    Sun, J.2    Jia, P.3    Zhao, Z.4
  • 47
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • Hebert S.S., De Strooper B. Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci. 2009, 32:199-206.
    • (2009) Trends Neurosci. , vol.32 , pp. 199-206
    • Hebert, S.S.1    De Strooper, B.2
  • 50
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 2010, 17:193-199.
    • (2010) Cell Death Differ. , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 52
    • 79951832466 scopus 로고    scopus 로고
    • Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells
    • Huang X., Gschweng E., Van Handel B., Cheng D., Mikkola H.K., Witte O.N. Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells. Blood 2011, 117:2157-2165.
    • (2011) Blood , vol.117 , pp. 2157-2165
    • Huang, X.1    Gschweng, E.2    Van Handel, B.3    Cheng, D.4    Mikkola, H.K.5    Witte, O.N.6
  • 54
    • 70350142444 scopus 로고    scopus 로고
    • Gene dysregulation in Huntington's disease: REST, microRNAs and beyond
    • Johnson R., Buckley N.J. Gene dysregulation in Huntington's disease: REST, microRNAs and beyond. Neuromolecular Med. 2009, 11:183-199.
    • (2009) Neuromolecular Med. , vol.11 , pp. 183-199
    • Johnson, R.1    Buckley, N.J.2
  • 56
    • 35248886076 scopus 로고    scopus 로고
    • Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin
    • Kawataki T., Yamane T., Naganuma H., Rousselle P., Anduren I., Tryggvason K., Patarroyo M. Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin. Exp. Cell Res. 2007, 313:3819-3831.
    • (2007) Exp. Cell Res. , vol.313 , pp. 3819-3831
    • Kawataki, T.1    Yamane, T.2    Naganuma, H.3    Rousselle, P.4    Anduren, I.5    Tryggvason, K.6    Patarroyo, M.7
  • 59
    • 37249042389 scopus 로고    scopus 로고
    • MicroRNA profiling: from dark matter to white matter, or identifying new players in neurobiology
    • Krichevsky A.M. MicroRNA profiling: from dark matter to white matter, or identifying new players in neurobiology. ScientificWorldJournal 2007, 7:155-166.
    • (2007) ScientificWorldJournal , vol.7 , pp. 155-166
    • Krichevsky, A.M.1
  • 60
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky A.M., King K.S., Donahue C.P., Khrapko K., Kosik K.S. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 2003, 9:1274-1281.
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 61
    • 33745480963 scopus 로고    scopus 로고
    • Specific microRNAs modulate embryonic stem cell-derived neurogenesis
    • Krichevsky A.M., Sonntag K.C., Isacson O., Kosik K.S. Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 2006, 24:857-864.
    • (2006) Stem Cells , vol.24 , pp. 857-864
    • Krichevsky, A.M.1    Sonntag, K.C.2    Isacson, O.3    Kosik, K.S.4
  • 67
    • 77958117982 scopus 로고    scopus 로고
    • MiR-124a is important for migratory cell fate transition during gastrulation of human embryonic stem cells
    • Lee M.R., Kim J.S., Kim K.S. miR-124a is important for migratory cell fate transition during gastrulation of human embryonic stem cells. Stem Cells 2010, 28:1550-1559.
    • (2010) Stem Cells , vol.28 , pp. 1550-1559
    • Lee, M.R.1    Kim, J.S.2    Kim, K.S.3
  • 69
    • 67349155172 scopus 로고    scopus 로고
    • MiR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1
    • Li K.K., Pang J.C., Ching A.K., Wong C.K., Kong X., Wang Y., Zhou L., Chen Z., Ng H.K. miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1. Hum. Pathol. 2009, 40:1234-1243.
    • (2009) Hum. Pathol. , vol.40 , pp. 1234-1243
    • Li, K.K.1    Pang, J.C.2    Ching, A.K.3    Wong, C.K.4    Kong, X.5    Wang, Y.6    Zhou, L.7    Chen, Z.8    Ng, H.K.9
  • 70
    • 71349087632 scopus 로고    scopus 로고
    • Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration
    • Li X., Shen Y., Ichikawa H., Antes T., Goldberg G.S. Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration. Oncogene 2009, 28:4272-4283.
    • (2009) Oncogene , vol.28 , pp. 4272-4283
    • Li, X.1    Shen, Y.2    Ichikawa, H.3    Antes, T.4    Goldberg, G.S.5
  • 71
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Liang Y., Ridzon D., Wong L., Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166.
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3    Chen, C.4
  • 73
    • 66049084202 scopus 로고    scopus 로고
    • MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo
    • Liu B., Peng X.C., Zheng X.L., Wang J., Qin Y.W. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer 2009, 66:169-175.
    • (2009) Lung Cancer , vol.66 , pp. 169-175
    • Liu, B.1    Peng, X.C.2    Zheng, X.L.3    Wang, J.4    Qin, Y.W.5
  • 74
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 76
    • 33847203593 scopus 로고    scopus 로고
    • Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw W.J. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007, 18:297-300.
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 77
    • 73249124152 scopus 로고    scopus 로고
    • Promotion of embryonic cortico-cerebral neuronogenesis by miR-124
    • Maiorano N.A., Mallamaci A. Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 2009, 4:40.
    • (2009) Neural Dev. , vol.4 , pp. 40
    • Maiorano, N.A.1    Mallamaci, A.2
  • 78
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev E.V., Zhang J., Carrasco M.A., Maniatis T. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 2007, 27:435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 80
    • 78349251242 scopus 로고    scopus 로고
    • MiR-126 and miR-126*: new players in cancer
    • Meister J., Schmidt M.H. miR-126 and miR-126*: new players in cancer. ScientificWorldJournal 2011, 10:2090-2100.
    • (2011) ScientificWorldJournal , vol.10 , pp. 2090-2100
    • Meister, J.1    Schmidt, M.H.2
  • 81
    • 52949109849 scopus 로고    scopus 로고
    • A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex
    • Mellios N., Huang H.S., Grigorenko A., Rogaev E., Akbarian S. A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum. Mol. Genet. 2008, 17:3030-3042.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3030-3042
    • Mellios, N.1    Huang, H.S.2    Grigorenko, A.3    Rogaev, E.4    Akbarian, S.5
  • 83
    • 77952574649 scopus 로고    scopus 로고
    • MicroRNA dysregulation in psychiatric disease
    • Miller B.H., Wahlestedt C. MicroRNA dysregulation in psychiatric disease. Brain Res. 2010, 1338:89-99.
    • (2010) Brain Res. , vol.1338 , pp. 89-99
    • Miller, B.H.1    Wahlestedt, C.2
  • 85
    • 71349085957 scopus 로고    scopus 로고
    • Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
    • Moloney A.M., Griffin R.J., Timmons S., O'Connor R., Ravid R., O'Neill C. Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling. Neurobiol. Aging 2010, 31:224-243.
    • (2010) Neurobiol. Aging , vol.31 , pp. 224-243
    • Moloney, A.M.1    Griffin, R.J.2    Timmons, S.3    O'Connor, R.4    Ravid, R.5    O'Neill, C.6
  • 86
    • 39849097124 scopus 로고    scopus 로고
    • Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like 7 gene, regulates prostein translation and invasiveness of prostate cancer LNCaP cells
    • Musiyenko A., Bitko V., Barik S. Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like 7 gene, regulates prostein translation and invasiveness of prostate cancer LNCaP cells. J. Mol. Med. 2008, 86:313-322.
    • (2008) J. Mol. Med. , vol.86 , pp. 313-322
    • Musiyenko, A.1    Bitko, V.2    Barik, S.3
  • 87
    • 27844458139 scopus 로고    scopus 로고
    • Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration
    • Nelson T.J., Alkon D.L. Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. Biochem. Soc. Trans. 2005, 33:1033-1036.
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 1033-1036
    • Nelson, T.J.1    Alkon, D.L.2
  • 88
    • 77954996105 scopus 로고    scopus 로고
    • MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study
    • Nelson P.T., Wang W.X. MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J. Alzheimers Dis. 2010, 21:75-79.
    • (2010) J. Alzheimers Dis. , vol.21 , pp. 75-79
    • Nelson, P.T.1    Wang, W.X.2
  • 90
    • 38349186896 scopus 로고    scopus 로고
    • MicroRNAs (miRNAs) in neurodegenerative diseases
    • Nelson P.T., Wang W.X., Rajeev B.W. MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol. 2008, 18:130-138.
    • (2008) Brain Pathol. , vol.18 , pp. 130-138
    • Nelson, P.T.1    Wang, W.X.2    Rajeev, B.W.3
  • 93
    • 70350217340 scopus 로고    scopus 로고
    • MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats
    • Olsen L., Klausen M., Helboe L., Nielsen F.C., Werge T. MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats. PLoS One 2009, 4:e7225.
    • (2009) PLoS One , vol.4
    • Olsen, L.1    Klausen, M.2    Helboe, L.3    Nielsen, F.C.4    Werge, T.5
  • 94
    • 79551511687 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis
    • Otsubo T., Akiyama Y., Hashimoto Y., Shimada S., Goto K., Yuasa Y. MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS One 2011, 6:e16617.
    • (2011) PLoS One , vol.6
    • Otsubo, T.1    Akiyama, Y.2    Hashimoto, Y.3    Shimada, S.4    Goto, K.5    Yuasa, Y.6
  • 95
    • 58149375393 scopus 로고    scopus 로고
    • The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
    • Packer A.N., Xing Y., Harper S.Q., Jones L., Davidson B.L. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci. 2008, 28:14341-14346.
    • (2008) J. Neurosci. , vol.28 , pp. 14341-14346
    • Packer, A.N.1    Xing, Y.2    Harper, S.Q.3    Jones, L.4    Davidson, B.L.5
  • 96
    • 79958207546 scopus 로고    scopus 로고
    • Neurodegenerative disease: miR-34b-a novel plasma marker for Huntington disease?
    • Parekh V. Neurodegenerative disease: miR-34b-a novel plasma marker for Huntington disease?. Nat. Rev. Neurol. 2011, 7:304.
    • (2011) Nat. Rev. Neurol. , vol.7 , pp. 304
    • Parekh, V.1
  • 98
    • 70349320089 scopus 로고    scopus 로고
    • MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion
    • Peterson K.J., Dietrich M.R., McPeek M.A. MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion. Bioessays 2009, 31:736-747.
    • (2009) Bioessays , vol.31 , pp. 736-747
    • Peterson, K.J.1    Dietrich, M.R.2    McPeek, M.A.3
  • 99
    • 67649619278 scopus 로고    scopus 로고
    • AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matrix
    • Piao Y., Lu L., de Groot J. AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matrix. Neuro Oncol. 2009, 11:260-273.
    • (2009) Neuro Oncol. , vol.11 , pp. 260-273
    • Piao, Y.1    Lu, L.2    de Groot, J.3
  • 100
    • 46349109152 scopus 로고    scopus 로고
    • Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
    • Pierson J., Hostager B., Fan R., Vibhakar R. Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J. Neurooncol 2008, 90:1-7.
    • (2008) J. Neurooncol , vol.90 , pp. 1-7
    • Pierson, J.1    Hostager, B.2    Fan, R.3    Vibhakar, R.4
  • 101
    • 79960963456 scopus 로고    scopus 로고
    • Neuronal type-specific gene expression profiling and laser-capture microdissection
    • Pietersen C.Y., Lim M.P., Macey L., Woo T.U., Sonntag K.C. Neuronal type-specific gene expression profiling and laser-capture microdissection. Methods Mol. Biol. 2011, 755:327-343.
    • (2011) Methods Mol. Biol. , vol.755 , pp. 327-343
    • Pietersen, C.Y.1    Lim, M.P.2    Macey, L.3    Woo, T.U.4    Sonntag, K.C.5
  • 102
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
    • Ponomarev E.D., Veremeyko T., Barteneva N., Krichevsky A.M., Weiner H.L. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat. Med. 2011, 17:64-70.
    • (2011) Nat. Med. , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    Weiner, H.L.5
  • 103
    • 0347629016 scopus 로고    scopus 로고
    • Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions
    • Quesada A., Micevych P.E. Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions. J. Neurosci. Res. 2004, 75:107-116.
    • (2004) J. Neurosci. Res. , vol.75 , pp. 107-116
    • Quesada, A.1    Micevych, P.E.2
  • 104
    • 41549156954 scopus 로고    scopus 로고
    • PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease
    • Quesada A., Lee B.Y., Micevych P.E. PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. Dev. Neurobiol. 2008, 68:632-644.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 632-644
    • Quesada, A.1    Lee, B.Y.2    Micevych, P.E.3
  • 106
    • 79953048345 scopus 로고    scopus 로고
    • The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes
    • Ryu H.S., Park S.Y., Ma D., Zhang J., Lee W. The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes. PLoS One 2011, 6:e17343.
    • (2011) PLoS One , vol.6
    • Ryu, H.S.1    Park, S.Y.2    Ma, D.3    Zhang, J.4    Lee, W.5
  • 107
    • 78650511568 scopus 로고    scopus 로고
    • Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia
    • Santarelli D.M., Beveridge N.J., Tooney P.A., Cairns M.J. Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol. Psychiatry 2011, 69:180-187.
    • (2011) Biol. Psychiatry , vol.69 , pp. 180-187
    • Santarelli, D.M.1    Beveridge, N.J.2    Tooney, P.A.3    Cairns, M.J.4
  • 109
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere L.F., Freemantle S., Pitha-Rowe I., Moss E., Dmitrovsky E., Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 2004, 5:R13.
    • (2004) Genome Biol. , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 113
    • 77749309959 scopus 로고    scopus 로고
    • Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease
    • Simunovic F., Yi M., Wang Y., Stephens R., Sonntag K.C. Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease. PLoS One 2010, 5:e8856.
    • (2010) PLoS One , vol.5
    • Simunovic, F.1    Yi, M.2    Wang, Y.3    Stephens, R.4    Sonntag, K.C.5
  • 114
    • 34548711881 scopus 로고    scopus 로고
    • MiRNAs: from neurogeneration to neurodegeneration
    • Singh S.K. miRNAs: from neurogeneration to neurodegeneration. Pharmacogenomics 2007, 8:971-978.
    • (2007) Pharmacogenomics , vol.8 , pp. 971-978
    • Singh, S.K.1
  • 116
    • 78650692019 scopus 로고    scopus 로고
    • In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs
    • Smith P., Al Hashimi A., Girard J., Delay C., Hebert S.S. In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs. J. Neurochem. 2011, 116:240-247.
    • (2011) J. Neurochem. , vol.116 , pp. 240-247
    • Smith, P.1    Al Hashimi, A.2    Girard, J.3    Delay, C.4    Hebert, S.S.5
  • 117
    • 77952675535 scopus 로고    scopus 로고
    • MicroRNAs and deregulated gene expression networks in neurodegeneration
    • Sonntag K.C. MicroRNAs and deregulated gene expression networks in neurodegeneration. Brain Res. 2010, 1338:48-57.
    • (2010) Brain Res. , vol.1338 , pp. 48-57
    • Sonntag, K.C.1
  • 119
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • Swartling F.J., Ferletta M., Kastemar M., Weiss W.A., Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 2009, 28:3121-3131.
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3    Weiss, W.A.4    Westermark, B.5
  • 120
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M., Suzuki H., Sasaki Y., Maruyama R., Imai K., Shinomura Y., Tokino T. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 2008, 68:4123-4132.
    • (2008) Cancer Res. , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6    Tokino, T.7
  • 121
    • 84857477485 scopus 로고    scopus 로고
    • Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation
    • Vachon P.H. Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation. J. Signal Transduct. 2011, 2011:738137.
    • (2011) J. Signal Transduct. , vol.2011 , pp. 738137
    • Vachon, P.H.1
  • 122
    • 34147157651 scopus 로고    scopus 로고
    • The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
    • Visvanathan J., Lee S., Lee B., Lee J.W., Lee S.K. The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 2007, 21:744-749.
    • (2007) Genes Dev. , vol.21 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.K.5
  • 124
    • 33645472191 scopus 로고    scopus 로고
    • Systematic identification of microRNA functions by combining target prediction and expression profiling
    • Wang X., Wang X. Systematic identification of microRNA functions by combining target prediction and expression profiling. Nucleic Acids Res. 2006, 34:1646-1652.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1646-1652
    • Wang, X.1    Wang, X.2
  • 127
    • 77955424349 scopus 로고    scopus 로고
    • Comparative profiling of microRNA expression between neural stem cells and motor neurons in embryonic spinal cord in rat
    • Wei H., Wang C., Zhang C., Li P., Wang F., Zhang Z. Comparative profiling of microRNA expression between neural stem cells and motor neurons in embryonic spinal cord in rat. Int. J. Dev. Neurosci. 2010, 28:545-551.
    • (2010) Int. J. Dev. Neurosci. , vol.28 , pp. 545-551
    • Wei, H.1    Wang, C.2    Zhang, C.3    Li, P.4    Wang, F.5    Zhang, Z.6
  • 130
    • 70350062072 scopus 로고    scopus 로고
    • Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway
    • Xu L., Chen W.F., Wong M.S. Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway. Br. J. Pharmacol. 2009, 158:738-748.
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 738-748
    • Xu, L.1    Chen, W.F.2    Wong, M.S.3
  • 131
    • 77952583640 scopus 로고    scopus 로고
    • MicroRNAs in psychiatric and neurodevelopmental disorders
    • Xu B., Karayiorgou M., Gogos J.A. MicroRNAs in psychiatric and neurodevelopmental disorders. Brain Res. 2010, 1338:78-88.
    • (2010) Brain Res. , vol.1338 , pp. 78-88
    • Xu, B.1    Karayiorgou, M.2    Gogos, J.A.3
  • 132
    • 62449117918 scopus 로고    scopus 로고
    • MiR-34, SIRT1 and p53: the feedback loop
    • Yamakuchi M., Lowenstein C.J. MiR-34, SIRT1 and p53: the feedback loop. Cell Cycle 2009, 8:712-715.
    • (2009) Cell Cycle , vol.8 , pp. 712-715
    • Yamakuchi, M.1    Lowenstein, C.J.2
  • 136
    • 79955569628 scopus 로고    scopus 로고
    • MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
    • Zhao S., Wang Y., Liang Y., Zhao M., Long H., Ding S., Yin H., Lu Q. MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum. 2011, 63:1376-1386.
    • (2011) Arthritis Rheum. , vol.63 , pp. 1376-1386
    • Zhao, S.1    Wang, Y.2    Liang, Y.3    Zhao, M.4    Long, H.5    Ding, S.6    Yin, H.7    Lu, Q.8
  • 137
    • 79953702227 scopus 로고    scopus 로고
    • Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2
    • Zhu N., Zhang D., Xie H., Zhou Z., Chen H., Hu T., Bai Y., Shen Y., Yuan W., Jing Q., Qin Y. Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. Mol. Cell. Biochem. 2011, 351:157-164.
    • (2011) Mol. Cell. Biochem. , vol.351 , pp. 157-164
    • Zhu, N.1    Zhang, D.2    Xie, H.3    Zhou, Z.4    Chen, H.5    Hu, T.6    Bai, Y.7    Shen, Y.8    Yuan, W.9    Jing, Q.10    Qin, Y.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.