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Volumn 38, Issue 6, 2012, Pages 643-652

Vaginal mucoadhesive drug delivery systems

Author keywords

Drug delivery systems; Mucoadhesion; Vaginal mucosa; Vaginal route; Vaginitis

Indexed keywords

ACETIC ACID; ADVANTAGE S; ALGINIC ACID; AMPHOTERICIN B; BUFFER GEL; CARBOMER; CARBOXYMETHYLCELLULOSE; CELLULOSE DERIVATIVE; CHITOSAN; CLINDAMYCIN; CLOMIREX; CLOTRIMAZOLE; CYCLODEXTRIN DERIVATIVE; ESTRADIOL; ETHYLENE OXIDE; FLUCONAZOLE; GLYCAN DERIVATIVE; GUAR GUM; GYNAZOLE; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; ITRACONAZOLE; K Y JELLY; KETOCONAZOLE; LIPOSOME; METRONIDAZOLE; MICONAZOLE; MIFLUOR; NONOXINOL 9; POLOXAMER; POLYCARBOPHIL; POLYMER; POVIDONE; PRO 2000 5; PROGESTERONE; PROPYLENE OXIDE; PROSTAGLANDIN E2; SYNPERONIC; TETRONIC; TETRONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VORICONAZOLE; XANTHAN;

EID: 84860358871     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.623355     Document Type: Review
Times cited : (117)

References (64)
  • 1
    • 57049181340 scopus 로고    scopus 로고
    • Microemulsion based vaginal gel of fluconazole: Formulation
    • in vitro and in vivo evaluation
    • Bachhav YG, Patravale VB. (2009). Microemulsion based vaginal gel of fluconazole: Formulation, in vitro and in vivo evaluation. Int J Pharm, 365:175-179
    • (2009) Int. J. Pharm. , vol.365 , pp. 175-179
    • Bachhav, Y.G.1    Patravale, V.B.2
  • 3
    • 14844314490 scopus 로고    scopus 로고
    • The vagina as a route for systemic drug delivery
    • DOI 10.1016/j.jconrel.2004.11.034, PII S0168365904006297
    • Hussain A, Ahsan F. (2005). The vagina as a route for systemic drug delivery. J Control Release, 103:301-313 (Pubitemid 40342532)
    • (2005) Journal of Controlled Release , vol.103 , Issue.2 , pp. 301-313
    • Hussain, A.1    Ahsan, F.2
  • 5
    • 26844560127 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in vaginal delivery
    • DOI 10.1016/j.addr.2005.07.004, PII S0169409X05001456, Mucoadhesive Polymers: Strategies, Achievements and Future Challenges
    • Valenta C. (2005). The use of mucoadhesive polymers in vaginal delivery. Adv Drug Deliv Rev, 57:1692-1712 (Pubitemid 41444256)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.11 , pp. 1692-1712
    • Valenta, C.1
  • 6
    • 31144448147 scopus 로고    scopus 로고
    • The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system
    • DOI 10.1016/j.ijpharm.2005.11.020, PII S0378517305007696
    • Yoo JW, Dharmala K, Lee CH. (2006). The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system. Int J Pharm, 309:139-145 (Pubitemid 43129476)
    • (2006) International Journal of Pharmaceutics , vol.309 , Issue.1-2 , pp. 139-145
    • Yoo, J.-W.1    Dharmala, K.2    Lee, C.H.3
  • 7
    • 77954817534 scopus 로고    scopus 로고
    • Investigation of the physicochemical and physicomechanical properties of a novel intravaginal bioadhesive polymeric device in the pig model
    • Ndesendo VM, Pillay V, Choonara YE, du Toit LC, Buchmann E, Meyer LC et al. (2010). Investigation of the physicochemical and physicomechanical properties of a novel intravaginal bioadhesive polymeric device in the pig model. AAPS PharmSciTech, 11:793-808
    • (2010) AAPS Pharm. Sci. Tech. , vol.11 , pp. 793-808
    • Ndesendo, V.M.1    Pillay, V.2    Choonara, Y.E.3    Du Toit, L.C.4    Buchmann, E.5    Meyer, L.C.6
  • 8
    • 12444285859 scopus 로고    scopus 로고
    • Liposomal gel with chloramphenicol: Characterisation and in vitro release
    • Pavelic Z, Skalko-Basnet N, Jalsenjak I. (2004). Liposomal gel with chloramphenicol: Characterisation and in vitro release. Acta Pharm, 54:319-330 (Pubitemid 40143817)
    • (2004) Acta Pharmaceutica , vol.54 , Issue.4 , pp. 319-330
    • Pavelic, Z.1    Skalko-Basnet, N.2    Jalsenjak, I.3
  • 9
    • 77953405780 scopus 로고    scopus 로고
    • Formulation development and characterization of metronidazole microencapsulated bioadhesive vaginal gel
    • Bhowmik BB, Nayak BS, Chatterjee A. (2009). Formulation development and characterization of metronidazole microencapsulated bioadhesive vaginal gel. Int J Pharm Pharmaceut Sci, 1:240-257
    • (2009) Int. J. Pharm. Pharmaceut Sci. , vol.1 , pp. 240-257
    • Bhowmik, B.B.1    Nayak, B.S.2    Chatterjee, A.3
  • 10
    • 59349094139 scopus 로고    scopus 로고
    • Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate
    • Albertini B, Passerini N, Di Sabatino M, Vitali B, Brigidi P, Rodriguez L. (2009). Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate. Eur J Pharm Sci, 36:591-601
    • (2009) Eur. J. Pharm. Sci. , vol.36 , pp. 591-601
    • Albertini, B.1    Passerini, N.2    Di Sabatino, M.3    Vitali, B.4    Brigidi, P.5    Rodriguez, L.6
  • 11
    • 84869298534 scopus 로고    scopus 로고
    • Mucoadhesive thermosensitive prolonged-release vaginal gel for clotrimazole: β-cyclodextrin complex
    • Bilensoy E, Rouf MA, Vural I, Sen M, Hincal AA. (2006). Mucoadhesive, thermosensitive, prolonged-release vaginal gel for clotrimazole: β-cyclodextrin complex. AAPS PharmSciTech, 7:38
    • (2006) AAPS Pharm. Sci. Tech. , vol.7 , pp. 38
    • Bilensoy, E.1    Rouf, M.A.2    Vural, I.3    Sen, M.4    Hincal, A.A.5
  • 13
    • 0037130164 scopus 로고    scopus 로고
    • Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis
    • Chang JY, Oh YK, Kong HS, Kim EJ, Jang DD, Nam KT et al. (2002). Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis. J Control Release, 82:39-50
    • (2002) J. Control Release , vol.82 , pp. 39-50
    • Chang, J.Y.1    Oh, Y.K.2    Kong, H.S.3    Kim, E.J.4    Jang, D.D.5    Nam, K.T.6
  • 15
    • 79953201893 scopus 로고    scopus 로고
    • Ion activated bioadhesive in situ gel of clindamycin for vaginal application
    • Gupta H, Sharma A. (2009). Ion activated bioadhesive in situ gel of clindamycin for vaginal application. Int J Drug Del, 1:32-40
    • (2009) Int. J. Drug. Del. , vol.1 , pp. 32-40
    • Gupta, H.1    Sharma, A.2
  • 16
    • 77953449683 scopus 로고    scopus 로고
    • A novel effervescent bioadhesive vaginal tablet of ketoconazole: Formulation band in vitro evaluation
    • Patel GM, Patel AP. (2010). A novel effervescent bioadhesive vaginal tablet of ketoconazole: Formulation band in vitro evaluation. Int J PharmTech Res, 2:656-667
    • (2010) Int. J. Pharm. Tech. Res. , vol.2 , pp. 656-667
    • Patel, G.M.1    Patel, A.P.2
  • 17
    • 33748853479 scopus 로고    scopus 로고
    • Once daily bioadhesive vaginal clotrimazole tablets: Design and evaluation
    • Sharma G, Jain S, Tiwary AK, Kaur G. (2006). Once daily bioadhesive vaginal clotrimazole tablets: Design and evaluation. Acta Pharm, 56:337-345 (Pubitemid 44422513)
    • (2006) Acta Pharmaceutica , vol.56 , Issue.3 , pp. 337-345
    • Sharma, G.1    Jain, S.2    Tiwary, A.K.3    Kaur, G.4
  • 18
    • 38349169237 scopus 로고    scopus 로고
    • A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: Design in vitro and in vivo evaluation
    • Wang L, Tang X. (2008). A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: Design, in vitro and in vivo evaluation. Int J Pharm, 350:181-187
    • (2008) Int. J. Pharm. , vol.350 , pp. 181-187
    • Wang, L.1    Tang, X.2
  • 20
    • 84860369465 scopus 로고    scopus 로고
    • Liposomal drug delivery of metronidazole for the local treatment of vaginitis
    • Patel DB, Patel JK. (2009). Liposomal drug delivery of metronidazole for the local treatment of vaginitis. Int J Pharm Sci Nanotech, 2:421-427
    • (2009) Int. J. Pharm. Sci. Nanotech , vol.2 , pp. 421-427
    • Patel, D.B.1    Patel, J.K.2
  • 21
    • 67649646738 scopus 로고    scopus 로고
    • FG90 chitosan as a new polymer for metronidazole mucoadhesive tablets for vaginal administration
    • Perioli L, Ambrogi V, Pagano C, Scuota S, Rossi C. (2009a). FG90 chitosan as a new polymer for metronidazole mucoadhesive tablets for vaginal administration. Int J Pharm, 377:120-127
    • (2009) Int. J. Pharm. , vol.377 , pp. 120-127
    • Perioli, L.1    Ambrogi, V.2    Pagano, C.3    Scuota, S.4    Rossi, C.5
  • 25
    • 58149154649 scopus 로고    scopus 로고
    • Development and in vitro evaluation of an acid buffering bioadhesive vaginal gel for mixed vaginal infections
    • Ahmad FJ, Alam MA, Khan ZI, Khar RK, Ali M. (2008). Development and in vitro evaluation of an acid buffering bioadhesive vaginal gel for mixed vaginal infections. Acta Pharm, 58:407-419
    • (2008) Acta. Pharm. , vol.58 , pp. 407-419
    • Ahmad, F.J.1    Alam, M.A.2    Khan, Z.I.3    Khar, R.K.4    Ali, M.5
  • 26
    • 37549071832 scopus 로고    scopus 로고
    • Development and evaluation of acid-buffering bioadhesive vaginal tablet for mixed vaginal infections
    • Alam MA, Ahmad FJ, Khan ZI, Khar RK, Ali M. (2007). Development and evaluation of acid-buffering bioadhesive vaginal tablet for mixed vaginal infections. AAPS PharmSciTech, 8:109
    • (2007) AAPS Pharm. Sci. Tech. , vol.8 , pp. 109
    • Alam, M.A.1    Ahmad, F.J.2    Khan, Z.I.3    Khar, R.K.4    Ali, M.5
  • 28
    • 18044393199 scopus 로고    scopus 로고
    • Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent
    • DOI 10.1007/s11095-005-2490-1
    • Garg S, Vermani K, Garg A, Anderson RA, Rencher WB, Zaneveld LJ. (2005). Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent. Pharm Res, 22:584-595 (Pubitemid 40603256)
    • (2005) Pharmaceutical Research , vol.22 , Issue.4 , pp. 584-595
    • Garg, S.1    Vermani, K.2    Garg, A.3    Anderson, R.A.4    Rencher, W.B.5    Zaneveld, L.J.D.6
  • 29
    • 70350783290 scopus 로고    scopus 로고
    • Formulation and evaluation of bioadhesive gels containing miconazole nitrate
    • Ramadan AA. (2008). Formulation and evaluation of bioadhesive gels containing miconazole nitrate. J App. Sci Res, 4:1052-1065
    • (2008) J. App. Sci. Res. , vol.4 , pp. 1052-1065
    • Ramadan, A.A.1
  • 30
    • 34047118513 scopus 로고    scopus 로고
    • Thermosensitive mucoadhesive gel formulation loaded with 5-Fu: Cyclodextrin complex for HPV-induced cervical cancer
    • Bilensoy E, Çirpanli Y, Şen M, Doǧan L, Çaliş S. (2007). Thermosensitive mucoadhesive gel formulation loaded with 5-Fu: Cyclodextrin complex for HPV-induced cervical cancer. J Incl Phenom Macrocycl Chem, 57:363-370
    • (2007) J. Incl. Phenom. Macrocycl. Chem. , vol.57 , pp. 363-370
    • Bilensoy, E.1    Çirpanli, Y.2    Şen, M.3    Doǧan, L.4    Çaliş, S.5
  • 31
    • 79955945011 scopus 로고    scopus 로고
    • A double-blind placebocontrolled study of 5-fluorouracil: Cyclodextrin complex loaded thermosensitive gel for the treatment of HPV induced condyloma
    • Bilensoy E, Moroy P, Çirpanli Y, Bilensoy T, Çaliş S, Mollamahmutoglu L. (2011). A double-blind placebocontrolled study of 5-fluorouracil: Cyclodextrin complex loaded thermosensitive gel for the treatment of HPV induced condyloma. J Incl Phenom Macrocycl Chem, 69:309-313
    • (2011) J. Incl. Phenom. Macrocycl. Chem. , vol.69 , pp. 309-313
    • Bilensoy, E.1    Moroy, P.2    Çirpanli, Y.3    Bilensoy, T.4    Çaliş, S.5    Mollamahmutoglu, L.6
  • 33
    • 31544467845 scopus 로고    scopus 로고
    • Thermosensitive and mucoadhesive delivery systems of mucosal vaccines
    • DOI 10.1016/j.ymeth.2005.10.003, PII S1046202305002288
    • Han IK, Kim YB, Kang HS, Sul D, Jung WW, Cho HJ et al. (2006). Thermosensitive and mucoadhesive delivery systems of mucosal vaccines. Methods, 38:106-111 (Pubitemid 43163470)
    • (2006) Methods , vol.38 , Issue.2 , pp. 106-111
    • Han, I.-K.1    Kim, Y.B.2    Kang, H.-S.3    Sul, D.4    Jung, W.-W.5    Cho, H.J.6    Oh, Y.-K.7
  • 36
  • 38
    • 65549159648 scopus 로고    scopus 로고
    • Vaginal drug delivery systems for HIV prevention
    • Rohan LC, Sassi AB. (2009). Vaginal drug delivery systems for HIV prevention. AAPS Pharm Sci Tech, 11:78-87
    • (2009) AAPS Pharm. Sci. Tech. , vol.11 , pp. 78-87
    • Rohan, L.C.1    Sassi, A.B.2
  • 39
  • 40
    • 0026671198 scopus 로고
    • Principle and investigation of the bioadhesion mechanism of solid dosage forms
    • Duchêne D, Ponchel G. (1992). Principle and investigation of the bioadhesion mechanism of solid dosage forms. Biomaterials, 13:709-714
    • (1992) Biomaterials , vol.13 , pp. 709-714
    • Duchêne, D.1    Ponchel, G.2
  • 42
    • 76249115874 scopus 로고    scopus 로고
    • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
    • USA
    • Lai SK, Wang YY, Hida K, Cone R, Hanes J. (2010). Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proc Natl Acad Sci USA, 107:598-603
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 598-603
    • Lai, S.K.1    Wang, Y.Y.2    Hida, K.3    Cone, R.4    Hanes, J.5
  • 44
    • 34548037865 scopus 로고    scopus 로고
    • Semisolid systems containing propolis for the treatment of periodontal disease: In vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties
    • DOI 10.1002/jps.20843
    • Bruschi ML, Jones DS, Panzeri H, Gremião MP, de Freitas O, Lara EH. (2007). Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. J Pharm Sci, 96:2074-2089 (Pubitemid 47280102)
    • (2007) Journal of Pharmaceutical Sciences , vol.96 , Issue.8 , pp. 2074-2089
    • Bruschi, M.L.1    Jones, D.S.2    Panzeri, H.3    Gremiao, M.P.D.4    De Freitas, O.5    Lara, E.H.G.6
  • 45
    • 29344433633 scopus 로고    scopus 로고
    • Lifetime changes in the vulva and vagina
    • DOI 10.1007/s00404-005-0079-x
    • Farage M, Maibach H. (2006). Lifetime changes in the vulva and vagina. Arch Gynecol Obstet, 273:195-202 (Pubitemid 43004689)
    • (2006) Archives of Gynecology and Obstetrics , vol.273 , Issue.4 , pp. 195-202
    • Farage, M.1    Maibach, H.2
  • 46
    • 2642673603 scopus 로고    scopus 로고
    • Adherence of human vaginal lactobacilli to vaginal epithelial cells and interaction with uropathogens
    • Boris S, Suárez JE, Vázquez F, Barbés C. (1998). Adherence of human vaginal lactobacilli to vaginal epithelial cells and interaction with uropathogens. Infect Immun, 66:1985-1989 (Pubitemid 28194093)
    • (1998) Infection and Immunity , vol.66 , Issue.5 , pp. 1985-1989
    • Boris, S.1    Suarez, J.E.2    Vazquez, F.3    Barbes, C.4
  • 48
    • 84860366557 scopus 로고    scopus 로고
    • Antifungal activity of brazilian propolis microparticles against yeasts isolated from vulvovaginal candidiasis
    • Dota KFD, Consolaro MEL, Svidzinski TIE, Bruschi ML. (2010). Antifungal activity of brazilian propolis microparticles against yeasts isolated from vulvovaginal candidiasis. eCAM Adv Access, 12:1-8
    • (2010) ECAM Adv. Access. , vol.12 , pp. 1-8
    • Dota, K.F.D.1    Consolaro, M.E.L.2    Svidzinski, T.I.E.3    Bruschi, M.L.4
  • 49
    • 34648819702 scopus 로고    scopus 로고
    • Dynamics of vaginal bacterial communities in women developing bacterial vaginosis, candidiasis, or no infection, analyzed by PCR-denaturing gradient gel electrophoresis and real-time PCR
    • DOI 10.1128/AEM.01251-07
    • Vitali B, Pugliese C, Biagi E, Candela M, Turroni S, Bellen G et al. (2007). Dynamics of vaginal bacterial communities in women developing bacterial vaginosis, candidiasis, or no infection, analyzed by PCR-denaturing gradient gel electrophoresis and realtime PCR. Appl Environ Microbiol, 73:5731-5741 (Pubitemid 47462983)
    • (2007) Applied and Environmental Microbiology , vol.73 , Issue.18 , pp. 5731-5741
    • Vitali, B.1    Pugliese, C.2    Biagi, E.3    Candela, M.4    Turroni, S.5    Bellen, G.6    Donders, G.G.G.7    Brigidi, P.8
  • 50
    • 77953245902 scopus 로고    scopus 로고
    • Desenvolvimento e caracterização de sistemas de liberação de própolis intrabolsa periodontal
    • São Paulo University Ribeirão Preto Brazil
    • Bruschi ML. (2006). Desenvolvimento e caracterização de sistemas de liberação de própolis intrabolsa periodontal. Doctorate thesis, Pharmaceutical Sciences Faculty, São Paulo University, Ribeirão Preto, Brazil
    • (2006) Doctorate Thesis Pharmaceutical Sciences Faculty
    • Bruschi, M.L.1
  • 52
    • 43249120415 scopus 로고    scopus 로고
    • Performance of an in vitro mucoadhesion testing method for vaginal semisolids: Influence of different testing conditions and instrumental parameters
    • das Neves J, Amaral MH, Bahia MF. (2008). Performance of an in vitro mucoadhesion testing method for vaginal semisolids: Influence of different testing conditions and instrumental parameters. Eur J Pharm Biopharm, 69:622-632
    • (2008) Eur. J. Pharm. Biopharm. , vol.69 , pp. 622-632
    • Das Neves, J.1    Amaral, M.H.2    Bahia, M.F.3
  • 53
    • 37349016042 scopus 로고    scopus 로고
    • Candidíase vulvovaginal: Fatores predisponentes do hospedeiro e virulência das leveduras
    • Álvares CA, Svidzinski TIE, Consolaro MEL. (2007). Candidíase vulvovaginal: Fatores predisponentes do hospedeiro e virulência das leveduras. J Bras Patol Med Lab, 43:319-327
    • (2007) J. Bras. Patol. Med. Lab. , vol.43 , pp. 319-327
    • Álvares, C.A.1    Svidzinski, T.I.E.2    Consolaro, M.E.L.3
  • 54
    • 0036189890 scopus 로고    scopus 로고
    • Over-The-Counter antifungal drug misuse associated with patient-diagnosed vulvovaginal candidiasis
    • DOI 10.1016/S0029-7844(01)01759-8, PII S0029784401017598
    • Ferris DG, Nyirjesy P, Sobel JD, Soper D, Pavletic A, Litaker MS. (2002). Over-the-counter antifungal drug misuse associated with patient-diagnosed vulvovaginal candidiasis. Obstet Gynecol, 99:419-425 (Pubitemid 34188402)
    • (2002) Obstetrics and Gynecology , vol.99 , Issue.3 , pp. 419-425
    • Ferris, D.G.1    Nyirjesy, P.2    Sobel, J.D.3    Soper, D.4    Pavletic, A.5    Litaker, M.S.6
  • 56
    • 0034004698 scopus 로고    scopus 로고
    • Microbicides: Forging scientific and political alliances
    • DOI 10.1089/108729100317803
    • Harrison PF. (2000). Microbicides: Forging scientific and political alliances. AIDS Patient Care STDS, 14:199-205 (Pubitemid 30225314)
    • (2000) AIDS Patient Care and STDs , vol.14 , Issue.4 , pp. 199-205
    • Harrison, P.F.1
  • 57
    • 33845351355 scopus 로고    scopus 로고
    • A review of poloxamer 407 pharmaceutical and pharmacological characteristics
    • DOI 10.1007/s11095-006-9104-4
    • Dumortier G, Grossiord JL, Agnely F, Chaumeil JC. (2006). review of poloxamer 407 pharmaceutical and pharmacological characteristics. Pharm Res, 23:2709-2728 (Pubitemid 44885361)
    • (2006) Pharmaceutical Research , vol.23 , Issue.12 , pp. 2709-2728
    • Dumortier, G.1    Grossiord, J.L.2    Agnely, F.3    Chaumeil, J.C.4
  • 58
    • 64149118639 scopus 로고    scopus 로고
    • Rheological mechanical and mucoadhesive properties of thermoresponsive bioadhesive binary mixtures composed of poloxamer 407 and carbopol 974P designed as platforms for implantable drug delivery systems for use in the oral cavity
    • Jones DS, Bruschi ML, de Freitas O, Gremião MP, Lara EH, Andrews GP. (2009). Rheological, mechanical and mucoadhesive properties of thermoresponsive, bioadhesive binary mixtures composed of poloxamer 407 and carbopol 974P designed as platforms for implantable drug delivery systems for use in the oral cavity. Int J Pharm, 372:49-58
    • (2009) Int. J. Pharm. , vol.372 , pp. 49-58
    • Jones, D.S.1    Bruschi, M.L.2    De Freitas, O.3    Gremião, M.P.4    Lara, E.H.5    Andrews, G.P.6
  • 59
    • 0035856812 scopus 로고    scopus 로고
    • Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone
    • DOI 10.1016/S0168-3659(01)00520-X, PII S016836590100520X
    • Valenta C, Kast CE, Harich I, Bernkop-Schnürch A. (2001). Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone. J Control Release, 77: 323-332 (Pubitemid 33145483)
    • (2001) Journal of Controlled Release , vol.77 , Issue.3 , pp. 323-332
    • Valenta, C.1    Kast, C.E.2    Harich, I.3    Bernkop-Schnurch, A.4
  • 60
    • 0037124497 scopus 로고    scopus 로고
    • Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole
    • DOI 10.1016/S0168-3659(02)00077-9, PII S0168365902000779
    • Kast CE, Valenta C, Leopold M, Bernkop-Schnürch A. (2002). Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole. J Control Release, 81:347-354 (Pubitemid 34607154)
    • (2002) Journal of Controlled Release , vol.81 , Issue.3 , pp. 347-354
    • Kast, C.E.1    Valenta, C.2    Leopold, M.3    Bernkop-Schnurch, A.4
  • 61
    • 33846523463 scopus 로고    scopus 로고
    • Chitosan gels for the vaginal delivery of lactic acid: Relevance of formulation parameters to mucoadhesion and release mechanisms
    • Bonferoni MC, Giunchedi P, Scalia S, Rossi S, Sandri G, Caramella C. (2006). Chitosan gels for the vaginal delivery of lactic acid: Relevance of formulation parameters to mucoadhesion and release mechanisms. AAPS PharmSciTech, 7:104
    • (2006) AAPS Pharm. Sci. Tech. , vol.7 , pp. 104
    • Bonferoni, M.C.1    Giunchedi, P.2    Scalia, S.3    Rossi, S.4    Sandri, G.5    Caramella, C.6
  • 62
    • 22244453965 scopus 로고    scopus 로고
    • Conceival a novel noncontraceptive vaginal vehicle for lipophilic microbicides
    • D Cruz OJ, Samuel P, Uckun FM. (2005). Conceival, a novel noncontraceptive vaginal vehicle for lipophilic microbicides. AAPS PharmSciTech, 6:56-64
    • (2005) AAPS Pharm. Sci. Tech. , vol.6 , pp. 56-64
    • D'Cruz, O.J.1    Samuel, P.2    Uckun, F.M.3
  • 63
    • 70350572286 scopus 로고    scopus 로고
    • Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses
    • Curran RM, Donnelly L, Morrow RJ, Fraser C, Andrews G, Cranage M et al. (2009). Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses. Vaccine, 27:6791-6798
    • (2009) Vaccine , vol.27 , pp. 6791-6798
    • Curran, R.M.1    Donnelly, L.2    Morrow, R.J.3    Fraser, C.4    Andrews, G.5    Cranage, M.6
  • 64


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.