Conceival, a novel noncontraceptive vaginal vehicle for lipophilic microbicides

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  D'Cruz, Osmond J ^a,b   Samuel, Peter ^a   Uckun, Fatih M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

^b Paradigm Pharmaceuticals   (United States)

Author keywords

HIV AIDS; Intravaginal; Lipophilic gel; Microbicide; Non contraceptive

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOIC ACID; CARBOXYMETHYLCELLULOSE; CONCEIVAL; CREMOPHOR; DRUG VEHICLE; GELUCIRE; LABRASOL; MACROGOL 400; MACROGOL STEARATE; MICROCRYSTALLINE CELLULOSE; N [2 (1 CYCLOHEXENYL)ETHYL] N' [2 (5 BROMOPYRIDYL)THIOUREA]; N' [2 (2 THIOPHENE)ETHYL] N' [2 (5 BROMOPYRIDYL)THIOUREA]; NONOXINOL 9; OLEIC ACID; PHI 113; PHI 346; PHI 443; POLYSORBATE 80; SORBITOL; STAMPIDINE; UNCLASSIFIED DRUG; WATER; XANTHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL INSEMINATION; CELL FUNCTION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EXPOSURE; DRUG SOLUBILITY; FEMALE; GEL; HISTOLOGY; IN VIVO STUDY; LIPOPHILICITY; MALE; MUCOSA INFLAMMATION; MULTIPLE DRUG DOSE; NEWBORN MORTALITY; NONHUMAN; PERINATAL DEVELOPMENT; PREGNANCY; PROCESS OPTIMIZATION; RABBIT; REPRODUCTION; SINGLE DRUG DOSE; SPERM; VAGINA; VAGINA EPITHELIUM; VASCULARIZATION;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; ANTI-INFECTIVE AGENTS; DEER; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; FEMALE; HUMANS; MALE; PREGNANCY; RABBITS; VAGINA;

EID: 22244453965     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060111     Document Type: Article

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