Once daily bioadhesive vaginal clotrimazole tablets: Design and evaluation

Acta Pharmaceutica

Volumn 56, Issue 3, 2006, Pages 337-345

  Sharma, Garima ^a   Jain, S ^a   Tiwary, A K ^a   Kaur, Gurpreet ^a  

^a PUNJABI UNIVERSITY   (India)

Author keywords

Bioadhesives; Carbopol 934P; Clotrimazole; Sodium alginate; Sodium carboxymethyl cellulose; Vaginal tablets

Indexed keywords

AGAR; ALGINIC ACID; CARBOMER; CARBOXYMETHYLCELLULOSE; CLOTRIMAZOLE;

ARTICLE; DRUG DESIGN; DRUG FORMULATION; DRUG SCREENING; HARDNESS; IN VITRO STUDY; METHODOLOGY; SWELLING; TABLET FORMULATION;

EID: 33748853479     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. E. Ghelardi, A. Tavati, A. Lupetti, F. Celandroni, E. Boldrini, M. Campa and S. Senesi, Control of Candida albicans murine vaginitis by topical administration of polycarbophil econazole complex, Antimicrob. Agents Chemother. 42 (1998) 2434-2436.
2. J. D. Smart, Drug delivery using buccal adhesive systems, Adv. Drug Deliv. Rev. 11 (1993) 253-270.
3. A. Valentin, C. Bernard, M. Mallic, M. Huerre and J. M. Bastide, Control of Candida albicans vaginitis in mice by short-duration butoconazole treatment in situ. Mycoses 36 (1993) 379-384.
4. J. Van Cutsem, The in vitro activity of tetraconazole against yeasts: its topical long-acting therapeutic efficacy in experimental vaginal candidiasis in rats, Am. J. Obstet. Gynecol. 165 (1991) 1200-1206.
5. J. L. Richardson and L. Ilium, Routes of delivery: Case studies. The vaginal route of peptide and protein drug delivery, Adv. Drug Deliv. Rev. 8 (1992) 341-366.
6. A. A. Deshpande, C. T. Rhodes and M. Danish, Intravaginal drug delivery, Drug Dev. Ind. Pharm. 18 (1992) 1225-1279.
7. L. Brannn-Peppas, Novel vaginal drug release application, Adv. Drug Deliv. Rev. 11 (1993) 169-177.
8. K. Knuth, M. Amiji and J. R. Robinson, Hydrogel delivery system for vaginal and oral applications, Adv. Drug Deliv. Rev. 11 (1993) 137-167.
9. J. R. Robinson and W. J. Bolonga, Vaginal and reproductive system treatments using a bioadhesive polymer, J. Control Rel. 28 (1996) 87-94.
10. D. Duchene, F. Touchard and N. A. Peppas, Pharmaceutical and medical aspects of bioadhesive systems for drug administration, Drug Dev. Ind. Pharm. 14 (1998) 283-318.
11. W. Ritter, K. Patasehke, U. Krause and S. Stettendorf, Pharmacokinetic fundamentals of vaginal treatment with CLT, Chemotherapy 28 (1982) 37-42.
12. C. Ronchi, F. Berlati and F. Scaglione, Solid anhydrous pharmaceutical compositions for vaginal use, Eur. Pat. 0770384 B 1, 6 Feb 2002; ref. Chem. Abstr. 127 (1997) 23754d.
13. L. Perioli, V. Ambrogi, D. Rubini, S. Giovagnoli, M. Ricci, P. Blasi and C. Rossi, Novel mucoadhesive buccal formulation containing metronidazole for treatment of periodontal disease, J. Control. Rel. 95 (2004) 521-533.
14. C. S. Yong, J. H. Jung, J. D. Rhee, C. K. Kim and H. G. Choi, Physicochemical characterisation and evaluation of buccal bioadhesive tablets containing omeprazole, Drug Dev. Ind. Pharm. 27 (2001) 447-455.
15. United States Pharmacopeia 28, National Formulary 23, United States Pharmacopeial Convention, Rockville 2005, pp. 2745.
16. nd ed., Government of India, New Delhi 1996, pp. 736.
17. H. Machida, H. Masuda, N. Fujiyama, S. Ito, M. Iwata and T. Nagai, Preparation and phase II clinical examination of topical dosage form for the treatment of carcinoma colli containing bleomycin with hydroxyl propyl cellulose, Chem. Pharm. Bull. 29 (1979) 93-100.
18. A. Gupta, S. Garg and R. K. Khar, Measurement of bioadhesive strength of mucoadhesive buccal tablet: design of an in vitro assembly, Indian Drugs 30 (1992) 152-154.
19. C. E. Kast, C. Valenta, M. Leopold and A. Bernkop-Schnürch, Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for CLT, J. Control. Rel. 81 (2002) 347-354.
20. N. A. Peppas and J. J. Sahlin, A simple equation of description of solute release III coupling of diffusion and relaxation, Int. J. Pharm. 57 (1989) 169-172.
21. J. E. Polli, G. S. Rekhi, L. L. Aussburger and V. P. Shah, Methods to compare dissolution profile and a rationale for wide dissolution specifications for metoprolol tartarate tablets, J. Pharm. Sci. 86 (1997) 690-700.
22. S. A. Mortazavi and J. D. Smart, An investigation of some factors influencing the in vitro assessment of mucoadhesion, Int. J. Pharm. 116 (1995) 223-230.
23. R. Khanna, S. P. Aggarwal and A. Ahuja, Preparation and evaluation of bioerodible buccal tablets containing clotrimazole, Int. J. Pharm. 139 (1996) 67-73.
24. N. A. Nafee, F. A. Ismail, N. A. Boraie and L. M. Mortada, Mucoadhesive delivery systems. I. evaluation of mucoadhesive polymers for buccal tablet formulation, Drug Dev. Ind. Pharm. 30 (2004) 985-993.
25. F. A. Mohammed and H. Khedr, Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow release tablets containing miconazole nitrate, Drug Dev. Ind. Pharm. 29 (2003) 321-337.
26. N. A. Peppas and P. Buri, Surface, interfactial and molecular aspects of polymer bioadhesion on soft tissues, J. Control. Rel. 2 (1985) 257-275.