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Volumn 61, Issue SUPPL. 1, 2012, Pages

New insight in the pathobiology of hepatitis B virus infection

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR DIPIVOXIL; ALPHA INTERFERON; CIRCULAR DNA; DOUBLE STRANDED DNA; HEPATITIS B ANTIBODY; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; RIBAVIRIN; VIRUS DNA;

EID: 84860337613     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2012-302056     Document Type: Review
Times cited : (215)

References (122)
  • 1
    • 35548983363 scopus 로고    scopus 로고
    • Molecular Virology of Hepatitis B Virus for Clinicians
    • DOI 10.1016/j.cld.2007.08.002, PII S1089326107000827, Chronic Hepatitis B
    • Block TM, Guo H, Guo JT. Molecular virology of hepatitis B virus for clinicians. Clin Liver Dis 2007;11:685-706, vii. (Pubitemid 350019022)
    • (2007) Clinics in Liver Disease , vol.11 , Issue.4 , pp. 685-706
    • Block, T.M.1    Guo, H.2    Guo, J.-T.3
  • 2
    • 7044241059 scopus 로고    scopus 로고
    • Prevention of hepatitis B virus-related hepatocellular carcinoma
    • DOI 10.1053/j.gastro.2004.09.045, PII S0016508504016245
    • Lok AS. Prevention of hepatitis B virus-related hepatocellular carcinoma. Gastroenterology 2004;127:S303-9. (Pubitemid 39423400)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • Lok, A.S.F.1
  • 3
    • 79961179769 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: The point of view of the hepatitis B virus
    • Pollicino T, Saitta C, Raimondo G. Hepatocellular carcinoma: the point of view of the hepatitis B virus. Carcinogenesis 2011;32:1122-32.
    • (2011) Carcinogenesis , vol.32 , pp. 1122-1132
    • Pollicino, T.1    Saitta, C.2    Raimondo, G.3
  • 4
    • 70349253352 scopus 로고    scopus 로고
    • Hepatitis B virus induced hepatocellular carcinoma
    • Chemin I, Zoulim F. Hepatitis B virus induced hepatocellular carcinoma. Cancer Lett 2009;286:52-9.
    • (2009) Cancer Lett , vol.286 , pp. 52-59
    • Chemin, I.1    Zoulim, F.2
  • 5
    • 33846538587 scopus 로고    scopus 로고
    • Viral and cellular determinants involved in hepadnaviral entry
    • Glebe D, Urban S. Viral and cellular determinants involved in hepadnaviral entry. World J Gastroenterol 2007;13:22-38. (Pubitemid 46165460)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.1 , pp. 22-38
    • Glebe, D.1    Urban, S.2
  • 6
    • 68049132846 scopus 로고    scopus 로고
    • Control of cccDNA function in hepatitis B virus infection
    • Levrero M, Pollicino T, Petersen J, et al. Control of cccDNA function in hepatitis B virus infection. J Hepatol 2009;51:581-92.
    • (2009) J Hepatol , vol.51 , pp. 581-592
    • Levrero, M.1    Pollicino, T.2    Petersen, J.3
  • 7
    • 0028013064 scopus 로고
    • Woodchuck hepatitis virus X protein is required for viral infection in vivo
    • Zoulim F, Saputelli J, Seeger C. Woodchuck hepatitis virus X protein is required for viral infection in vivo. J Virol 1994;68:2026-30. (Pubitemid 24065779)
    • (1994) Journal of Virology , vol.68 , Issue.3 , pp. 2026-2030
    • Zoulim, F.1    Saputelli, J.2    Seeger, C.3
  • 8
    • 79957614798 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection
    • Lucifora J, Arzberger S, Durantel D, et al. Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection. J Hepatol 2011;55:996-1003.
    • (2011) J Hepatol , vol.55 , pp. 996-1003
    • Lucifora, J.1    Arzberger, S.2    Durantel, D.3
  • 9
    • 43049117085 scopus 로고    scopus 로고
    • Hepatitis B viruses: Reverse transcription a different way
    • Nassal M. Hepatitis B viruses: reverse transcription a different way. Virus Res 2008;134:235-49.
    • (2008) Virus Res , vol.134 , pp. 235-249
    • Nassal, M.1
  • 10
    • 0027049665 scopus 로고
    • Molecular basis of hepatitis B virus serotype variations within the four major subtypes
    • Norder H, Courouce AM, Magnius LO. Molecular basis of hepatitis B virus serotype variations within the four major subtypes. J Gen Virol 1992;73:3141-5. (Pubitemid 23014164)
    • (1992) Journal of General Virology , vol.73 , Issue.12 , pp. 3141-3145
    • Norder, H.1    Courouce, A.-M.2    Magnius, L.O.3
  • 11
    • 0023943302 scopus 로고
    • Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: After signal peptide cleavage translocation can be aborted and the product released into the cytoplasm
    • Garcia PD, Ou JH, Rutter WJ, et al. Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol 1988;106:1093-104.
    • (1988) J Cell Biol , vol.106 , pp. 1093-1104
    • Garcia, P.D.1    Ou, J.H.2    Rutter, W.J.3
  • 12
    • 80052444371 scopus 로고    scopus 로고
    • The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway
    • Lang T, Lo C, Skinner N, et al. The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway. J Hepatol 2011;55:762-9.
    • (2011) J Hepatol , vol.55 , pp. 762-769
    • Lang, T.1    Lo, C.2    Skinner, N.3
  • 13
    • 74849108037 scopus 로고    scopus 로고
    • Bioinformatic analysis of the hepadnavirus e-antigen and its precursor identifies remarkable sequence conservation in all orthohepadnaviruses
    • Revill P, Yuen L, Walsh R, et al. Bioinformatic analysis of the hepadnavirus e-antigen and its precursor identifies remarkable sequence conservation in all orthohepadnaviruses. J Med Virol 2010;82:104-15.
    • (2010) J Med Virol , vol.82 , pp. 104-115
    • Revill, P.1    Yuen, L.2    Walsh, R.3
  • 14
    • 75349095571 scopus 로고    scopus 로고
    • The replication cycle of hepatitis B virus
    • Urban S, Schulze A, Dandri M, et al. The replication cycle of hepatitis B virus. J Hepatol 2010;52:282-4.
    • (2010) J Hepatol , vol.52 , pp. 282-284
    • Urban, S.1    Schulze, A.2    Dandri, M.3
  • 15
    • 77649199085 scopus 로고    scopus 로고
    • Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket
    • Schmitz A, Schwarz A, Foss M, et al. Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket. PLoS Pathog 2010;6:e1000741.
    • (2010) PLoS Pathog , vol.6
    • Schmitz, A.1    Schwarz, A.2    Foss, M.3
  • 16
    • 0029037074 scopus 로고
    • The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, et al. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol 1995;69:3350-7.
    • (1995) J Virol , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3
  • 17
    • 0036140134 scopus 로고    scopus 로고
    • Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
    • DOI 10.1053/jhep.2002.30203
    • Dandri M, Burda MR, Burkle A, et al. Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation. Hepatology 2002;35:217-23. (Pubitemid 34032563)
    • (2002) Hepatology , vol.35 , Issue.1 , pp. 217-223
    • Dandri, M.1    Burda, M.R.2    Burkle, A.3    Zuckerman, D.M.4    Will, H.5    Rogler, C.E.6    Greten, H.7    Petersen, J.8
  • 18
    • 0031916237 scopus 로고    scopus 로고
    • Liver repopulation with xenogenic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinoma
    • DOI 10.1073/pnas.95.1.310
    • Petersen J, Dandri M, Gupta S, et al. Liver repopulation with xenogenic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinoma. Proc Natl Acad Sci U S A 1998;95:310-15. (Pubitemid 28103950)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.1 , pp. 310-315
    • Petersen, J.1    Dandri, M.2    Gupta, S.3    Rogler, C.E.4
  • 20
    • 13844250599 scopus 로고    scopus 로고
    • New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA
    • DOI 10.1016/j.jhep.2004.12.015
    • Zoulim F. New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA. J Hepatol 2005;42:302-8. (Pubitemid 40254242)
    • (2005) Journal of Hepatology , vol.42 , Issue.3 , pp. 302-308
    • Zoulim, F.1
  • 22
    • 0034234540 scopus 로고    scopus 로고
    • Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA
    • Dandri M, Burda MR, Will H, et al. Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA. Hepatology 2000;32:139-46. (Pubitemid 30432379)
    • (2000) Hepatology , vol.32 , Issue.1 , pp. 139-146
    • Dandri, M.1    Burda, M.R.2    Will, H.3    Petersen, J.4
  • 24
    • 4644296081 scopus 로고    scopus 로고
    • Quantitation of covalently closed circular hepatitis B virus DNA in chronic B patients
    • DOI 10.1002/hep.20353
    • Wong DK, Yuen MF, Yuan H, et al. Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients. Hepatology 2004;40:727-37. (Pubitemid 39265596)
    • (2004) Hepatology , vol.40 , Issue.3 , pp. 727-737
    • Wong, D.K.-H.1    Yuen, M.-F.2    Yuan, H.3    Sum, S.S.-M.4    Hui, G.-K.5    Hall, J.6    Lai, C.-L.7
  • 25
    • 33748939050 scopus 로고    scopus 로고
    • Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients
    • DOI 10.1002/hep.21299
    • Laras A, Koskinas J, Dimou E, et al. Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients. Hepatology 2006;44:694-702. (Pubitemid 44433726)
    • (2006) Hepatology , vol.44 , Issue.3 , pp. 694-702
    • Laras, A.1    Koskinas, J.2    Dimou, E.3    Kostamena, A.4    Hadziyannis, S.J.5
  • 26
    • 34548475512 scopus 로고    scopus 로고
    • Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients
    • DOI 10.1053/j.gastro.2007.06.057, PII S0016508507012899
    • Volz T, Lutgehetmann M, Wachtler P, et al. Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients. Gastroenterology 2007;133:843-52. (Pubitemid 47374140)
    • (2007) Gastroenterology , vol.133 , Issue.3 , pp. 843-852
    • Volz, T.1    Lutgehetmann, M.2    Wachtler, P.3    Jacob, A.4    Quaas, A.5    Murray, J.M.6    Dandri, M.7    Petersen, J.8
  • 28
    • 42149135950 scopus 로고    scopus 로고
    • Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication
    • Lutgehetmann M, Volzt T, Quaas A, et al. Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication. Antivir Ther 2008;13:57-66. (Pubitemid 351541674)
    • (2008) Antiviral Therapy , vol.13 , Issue.1 , pp. 57-66
    • Lutgehetmann, M.1    Volz, T.2    Quaas, A.3    Zankel, M.4    Fischer, C.5    Dandri, M.6    Petersen, J.7
  • 30
    • 79958127932 scopus 로고    scopus 로고
    • Hepatitis B virus limits response of human hepatocytes to interferon-alpha in chimeric mice
    • Lutgehetmann M, Bornscheuer T, Volz T, et al. Hepatitis B virus limits response of human hepatocytes to interferon-alpha in chimeric mice. Gastroenterology 2011;140:2074-83.
    • (2011) Gastroenterology , vol.140 , pp. 2074-2083
    • Lutgehetmann, M.1    Bornscheuer, T.2    Volz, T.3
  • 31
    • 84857442747 scopus 로고    scopus 로고
    • Human chimeric uPA mouse model to study hepatitis B and D virus interactions and preclinical drug evaluation
    • Lutgehetmann M, Mancke LV, Volz T, et al. Human chimeric uPA mouse model to study hepatitis B and D virus interactions and preclinical drug evaluation. Hepatology 2012;55:685-94.
    • (2012) Hepatology , vol.55 , pp. 685-694
    • Lutgehetmann, M.1    Mancke, L.V.2    Volz, T.3
  • 32
    • 77954226664 scopus 로고    scopus 로고
    • In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
    • Lutgehetmann M, Volz T, Kopke A, et al. In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice. Hepatology 2010;52:16-24.
    • (2010) Hepatology , vol.52 , pp. 16-24
    • Lutgehetmann, M.1    Volz, T.2    Kopke, A.3
  • 33
    • 78149319907 scopus 로고    scopus 로고
    • Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner
    • Kock J, Rosler C, Zhang JJ, et al. Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner. PLoS Pathog 2010;6:e1001082.
    • (2010) PLoS Pathog , vol.6
    • Kock, J.1    Rosler, C.2    Zhang, J.J.3
  • 35
    • 80655146213 scopus 로고    scopus 로고
    • Roles of the envelope proteins in the amplification of covalently closed circular DNA and completion of synthesis of the plus-strand DNA in hepatitis B virus
    • Lentz TB, Loeb DD. Roles of the envelope proteins in the amplification of covalently closed circular DNA and completion of synthesis of the plus-strand DNA in hepatitis B virus. J Virol 2011;85:11916-27.
    • (2011) J Virol , vol.85 , pp. 11916-11927
    • Lentz, T.B.1    Loeb, D.D.2
  • 36
    • 58149296156 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: Management of chronic hepatitis B
    • European Association for the Study of the Liver
    • European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of chronic hepatitis B. J Hepatol 2009;50:227-42.
    • (2009) J Hepatol , vol.50 , pp. 227-242
  • 37
    • 33646369150 scopus 로고    scopus 로고
    • Hepatitis B e antigen-negative chronic hepatitis B: Natural history and treatment
    • DOI 10.1055/s-2006-939751
    • Hadziyannis SJ, Papatheodoridis GV. Hepatitis B e antigennegative chronic hepatitis B: natural history and treatment. Semin Liver Dis 2006;26:130-41. (Pubitemid 43668255)
    • (2006) Seminars in Liver Disease , vol.26 , Issue.2 , pp. 130-141
    • Hadziyannis, S.J.1    Papatheodoridis, G.V.2
  • 38
    • 84876033056 scopus 로고    scopus 로고
    • The role of quantitative hepatitis B serology in the natural history and management of chronic hepatitis B
    • Published Online First: 18 September doi:10.1007/s12072-009-9149-7
    • Nguyen T, Desmond P, Locarnini S. The role of quantitative hepatitis B serology in the natural history and management of chronic hepatitis B. Hepatol Int. Published Online First: 18 September 2009. doi:10.1007/s12072-009-9149-7
    • (2009) Hepatol Int
    • Nguyen, T.1    Desmond, P.2    Locarnini, S.3
  • 39
    • 77949656255 scopus 로고    scopus 로고
    • Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective
    • Jaroszewicz J, Calle Serrano B, Wursthorn K, et al. Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective. J Hepatol 2010;52:514-22.
    • (2010) J Hepatol , vol.52 , pp. 514-522
    • Jaroszewicz, J.1    Calle Serrano, B.2    Wursthorn, K.3
  • 40
    • 77955494346 scopus 로고    scopus 로고
    • Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers
    • Brunetto MR, Oliveri F, Colombatto P, et al. Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers. Gastroenterology 2010;139:483-90.
    • (2010) Gastroenterology , vol.139 , pp. 483-490
    • Brunetto, M.R.1    Oliveri, F.2    Colombatto, P.3
  • 41
    • 0036896285 scopus 로고    scopus 로고
    • Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection
    • DOI 10.1053/jhep.2002.36949
    • Chu CJ, Hussain M, Lok AS. Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection. Hepatology 2002;36:1408-15. (Pubitemid 35407438)
    • (2002) Hepatology , vol.36 , Issue.6 , pp. 1408-1415
    • Chu, C.-J.1    Hussain, M.2    Lok, A.S.F.3
  • 43
    • 0036789020 scopus 로고    scopus 로고
    • Prognosis following spontaneous HBsAg seroclearance in chronic hepatitis B patients with or without concurrent infection
    • Chen YC, Sheen IS, Chu CM, et al. Prognosis following spontaneous HBsAg seroclearance in chronic hepatitis B patients with or without concurrent infection. Gastroenterology 2002;123:1084-9.
    • (2002) Gastroenterology , vol.123 , pp. 1084-1089
    • Chen, Y.C.1    Sheen, I.S.2    Chu, C.M.3
  • 44
    • 38049044476 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
    • Fattovich G, Bortolotti F, Donato F. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol 2008;48:335-52.
    • (2008) J Hepatol , vol.48 , pp. 335-352
    • Fattovich, G.1    Bortolotti, F.2    Donato, F.3
  • 45
    • 59749096640 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Liaw YF, Chu CM. Hepatitis B virus infection. Lancet 2009;373:582-92.
    • (2009) Lancet , vol.373 , pp. 582-592
    • Liaw, Y.F.1    Chu, C.M.2
  • 46
    • 0037301154 scopus 로고    scopus 로고
    • Hepatitis C virus genetic variability: Pathogenic and clinical implications
    • Pawlotsky JM. Hepatitis C virus genetic variability: pathogenic and clinical implications. Clin Liver Dis 2003;7:45-66.
    • (2003) Clin Liver Dis , vol.7 , pp. 45-66
    • Pawlotsky, J.M.1
  • 47
    • 2342645459 scopus 로고    scopus 로고
    • The evolutionary adaptation of HIV-1 to specific immunity
    • da Silva J. The evolutionary adaptation of HIV-1 to specific immunity. Curr HIV Res 2003;1:363-71.
    • (2003) Curr HIV Res , vol.1 , pp. 363-371
    • Da Silva, J.1
  • 49
    • 0030000221 scopus 로고    scopus 로고
    • High rate of mutations in the hepatitis B core gene during the immune clearance phase of chronic hepatitis B virus infection
    • DOI 10.1053/jhep.1996.v24.pm0008707278
    • Bozkaya H, Ayola B, Lok AS. High rate of mutations in the hepatitis B core gene during the immune clearance phase of chronic hepatitis B virus infection. Hepatology 1996;24:32-7. (Pubitemid 26249409)
    • (1996) Hepatology , vol.24 , Issue.1 , pp. 32-37
    • Bozkaya, H.1    Ayola, B.2    Lok, A.S.F.3
  • 52
    • 33646366401 scopus 로고    scopus 로고
    • Serological and molecular diagnosis
    • DOI 10.1055/s-2006-939756
    • Bowden S. Serological and molecular diagnosis. Semin Liver Dis 2006;26:97-103. (Pubitemid 43668252)
    • (2006) Seminars in Liver Disease , vol.26 , Issue.2 , pp. 97-103
    • Bowden, S.1
  • 53
    • 42949142487 scopus 로고    scopus 로고
    • Hepatitis B virus infection and transfusion medicine: Science and the occult
    • DOI 10.1111/j.1537-2995.2008.01701.x
    • Hollinger FB. Hepatitis B virus infection and transfusion medicine: science and the occult. Transfusion 2008;48:1001-26. (Pubitemid 351614923)
    • (2008) Transfusion , vol.48 , Issue.5 , pp. 1001-1026
    • Hollinger, F.B.1
  • 56
    • 70349972123 scopus 로고    scopus 로고
    • Hepatitis: Monitoring drug therapy for hepatitis B - A global challenge?
    • Nguyen T, Locarnini S. Hepatitis: monitoring drug therapy for hepatitis B - a global challenge? Nat Rev Gastroenterol Hepatol 2009;6:565-7.
    • (2009) Nat Rev Gastroenterol Hepatol , vol.6 , pp. 565-567
    • Nguyen, T.1    Locarnini, S.2
  • 57
    • 84856514985 scopus 로고    scopus 로고
    • IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
    • Belloni L, Allweiss L, Guerrieri F, et al. IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome. J Clin Invest 2012;122:529-37.
    • (2012) J Clin Invest , vol.122 , pp. 529-537
    • Belloni, L.1    Allweiss, L.2    Guerrieri, F.3
  • 59
    • 77956037778 scopus 로고    scopus 로고
    • Interferons accelerate decay of replication-competent nucleocapsids of hepatitis B virus
    • Xu C, Guo H, Pan XB, et al. Interferons accelerate decay of replication-competent nucleocapsids of hepatitis B virus. J Virol 2010;84:9332-40.
    • (2010) J Virol , vol.84 , pp. 9332-9340
    • Xu, C.1    Guo, H.2    Pan, X.B.3
  • 61
    • 65449123444 scopus 로고    scopus 로고
    • Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
    • Moucari R, Mackiewicz V, Lada O, et al. Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology 2009;49:1151-7.
    • (2009) Hepatology , vol.49 , pp. 1151-1157
    • Moucari, R.1    Mackiewicz, V.2    Lada, O.3
  • 62
    • 65449117946 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen levels: A guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • Brunetto MR, Moriconi F, Bonino F, et al. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Hepatology 2009;49:1141-50.
    • (2009) Hepatology , vol.49 , pp. 1141-1150
    • Brunetto, M.R.1    Moriconi, F.2    Bonino, F.3
  • 63
    • 77957958049 scopus 로고    scopus 로고
    • Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline
    • Sonneveld MJ, Rijckborst V, Boucher CA, et al. Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline. Hepatology 2010;52:1251-7.
    • (2010) Hepatology , vol.52 , pp. 1251-1257
    • Sonneveld, M.J.1    Rijckborst, V.2    Boucher, C.A.3
  • 64
    • 80054724912 scopus 로고    scopus 로고
    • Hepatitis B surface antigen quantification: Why and how to use it in 2011- A core group report
    • Chan HL, Thompson A, Martinot-Peignoux M, et al. Hepatitis B surface antigen quantification: why and how to use it in 2011- a core group report. J Hepatol 2011;55:1121-31.
    • (2011) J Hepatol , vol.55 , pp. 1121-1131
    • Chan, H.L.1    Thompson, A.2    Martinot-Peignoux, M.3
  • 65
    • 77955703978 scopus 로고    scopus 로고
    • Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels
    • Rijckborst V, Hansen BE, Cakaloglu Y, et al. Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels. Hepatology 2010;52:454-61.
    • (2010) Hepatology , vol.52 , pp. 454-461
    • Rijckborst, V.1    Hansen, B.E.2    Cakaloglu, Y.3
  • 67
    • 33750964835 scopus 로고    scopus 로고
    • One-year entecavir or lamivudine therapy results in reduction of hepatitis B virus intrahepatic covalently closed circular DNA levels
    • Wong DK, Yuen MF, Ngai VW, et al. One-year entecavir or lamivudine therapy results in reduction of hepatitis B virus intrahepatic covalently closed circular DNA levels. Antivir Ther 2006;11:909-16. (Pubitemid 44736182)
    • (2006) Antiviral Therapy , vol.11 , Issue.7 , pp. 909-916
    • Wong, D.K.-H.1    Yuen, M.-F.2    Ngai, V.W.-S.3    Fung, J.4    Lai, C.-L.5
  • 68
    • 77952716572 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
    • Thompson AJ, Nguyen T, Iser D, et al. Serum hepatitis B surface antigen and hepatitis B e antigen titers: disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers. Hepatology 2010;51:1933-44.
    • (2010) Hepatology , vol.51 , pp. 1933-1944
    • Thompson, A.J.1    Nguyen, T.2    Iser, D.3
  • 69
    • 78650040589 scopus 로고    scopus 로고
    • Replicative and transcriptional activities of hepatitis B virus in patients coinfected with hepatitis B and hepatitis delta viruses
    • Pollicino T, Raffa G, Santantonio T, et al. Replicative and transcriptional activities of hepatitis B virus in patients coinfected with hepatitis B and hepatitis delta viruses. J Virol 2011;85:432-9.
    • (2011) J Virol , vol.85 , pp. 432-439
    • Pollicino, T.1    Raffa, G.2    Santantonio, T.3
  • 70
    • 79958800541 scopus 로고    scopus 로고
    • Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B
    • Manesis EK, Papatheodoridis GV, Tiniakos DG, et al. Hepatitis B surface antigen: relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B. J Hepatol 2011;55:61-8.
    • (2011) J Hepatol , vol.55 , pp. 61-68
    • Manesis, E.K.1    Papatheodoridis, G.V.2    Tiniakos, D.G.3
  • 71
    • 80054009688 scopus 로고    scopus 로고
    • Hepatitis B virus genotype C isolates with wild-type core promoter sequence replicate less efficiently than genotype B isolates but possess higher virion secretion capacity
    • Qin Y, Tang X, Garcia T, et al. Hepatitis B virus genotype C isolates with wild-type core promoter sequence replicate less efficiently than genotype B isolates but possess higher virion secretion capacity. J Virol 2011;85:10167-77.
    • (2011) J Virol , vol.85 , pp. 10167-10177
    • Qin, Y.1    Tang, X.2    Garcia, T.3
  • 72
    • 47149111970 scopus 로고    scopus 로고
    • The antiviral drug selected hepatitis B virus rtA181T/sW172*mutant has a dominant negative secretion defect and alters the typical profile of viral rebound
    • DOI 10.1002/hep.22295
    • Warner N, Locarnini S. The antiviral drug selected hepatitis B virus rtA181T/sW172*mutant has a dominant negative secretion defect and alters the typical profile of viral rebound. Hepatology 2008;48:88-98. (Pubitemid 351975534)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 88-98
    • Warner, N.1    Locarnini, S.2
  • 73
    • 78649413761 scopus 로고    scopus 로고
    • Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site
    • Ito K, Qin Y, Guarnieri M, et al. Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site. J Virol 2010;84:12850-61.
    • (2010) J Virol , vol.84 , pp. 12850-12861
    • Ito, K.1    Qin, Y.2    Guarnieri, M.3
  • 74
    • 70350095437 scopus 로고    scopus 로고
    • Hepatitis B virus resistance to nucleos(t) ide analogues
    • Zoulim F, Locarnini S. Hepatitis B virus resistance to nucleos(t) ide analogues. Gastroenterology 2009;137:1593-608, e1-2.
    • (2009) Gastroenterology , vol.137
    • Zoulim, F.1    Locarnini, S.2
  • 75
    • 0033998463 scopus 로고    scopus 로고
    • Intrahepatic induction of alpha/beta interferon eliminates viral RNA- containing capsids in hepatitis B virus transgenic mice
    • DOI 10.1128/JVI.74.9.4165-4173.2000
    • Wieland SF, Guidotti LG, Chisari FV. Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice. J Virol 2000;74:4165-73. (Pubitemid 30214422)
    • (2000) Journal of Virology , vol.74 , Issue.9 , pp. 4165-4173
    • Wieland, S.F.1    Guidotti, L.G.2    Chisari, F.V.3
  • 77
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • DOI 10.1038/nri1573
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 2005;5:215-29. (Pubitemid 40364823)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.3 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 78
    • 0033617583 scopus 로고    scopus 로고
    • Viral clearance without destruction of infected cells during acute HBV infection
    • DOI 10.1126/science.284.5415.825
    • Guidotti LG, Rochford R, Chung J, et al. Viral clearance without destruction of infected cells during acute HBV infection. Science 1999;284:825-9. (Pubitemid 29291352)
    • (1999) Science , vol.284 , Issue.5415 , pp. 825-829
    • Guidotti, L.G.1    Rochford, R.2    Chung, J.3    Shapiro, M.4    Purcell, R.5    Chisari, F.V.6
  • 80
    • 70349435373 scopus 로고    scopus 로고
    • Temporal analysis of early immune responses in patients with acute hepatitis B virus infection
    • Dunn C, Peppa D, Khanna P, et al. Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology 2009;137:1289-300.
    • (2009) Gastroenterology , vol.137 , pp. 1289-1300
    • Dunn, C.1    Peppa, D.2    Khanna, P.3
  • 82
    • 73449093499 scopus 로고    scopus 로고
    • Control of hepatitis B virus replication by innate response of HepaRG cells
    • Lucifora J, Durantel D, Testoni B, et al. Control of hepatitis B virus replication by innate response of HepaRG cells. Hepatology 2010;51:63-72.
    • (2010) Hepatology , vol.51 , pp. 63-72
    • Lucifora, J.1    Durantel, D.2    Testoni, B.3
  • 83
    • 18744399291 scopus 로고    scopus 로고
    • Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
    • DOI 10.1128/JVI.79.11.7269-7272.2005
    • Isogawa M, Robek MD, Furuichi Y, et al. Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. J Virol 2005;79:7269-72. (Pubitemid 40677357)
    • (2005) Journal of Virology , vol.79 , Issue.11 , pp. 7269-7272
    • Isogawa, M.1    Robek, M.D.2    Furuichi, Y.3    Chisari, F.V.4
  • 84
    • 37749050365 scopus 로고    scopus 로고
    • Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice
    • Wu J, Lu M, Meng Z, et al. Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice. Hepatology 2007;46:1769-78.
    • (2007) Hepatology , vol.46 , pp. 1769-1778
    • Wu, J.1    Lu, M.2    Meng, Z.3
  • 85
    • 3242711262 scopus 로고    scopus 로고
    • Innate sensing of viruses by Toll-like receptors
    • DOI 10.1128/JVI.78.15.7867-7873.2004
    • Boehme KW, Compton T. Innate sensing of viruses by toll-like receptors. J Virol 2004;78:7867-73. (Pubitemid 38944272)
    • (2004) Journal of Virology , vol.78 , Issue.15 , pp. 7867-7873
    • Boehme, K.W.1    Compton, T.2
  • 86
    • 0036839079 scopus 로고    scopus 로고
    • Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic micet
    • DOI 10.1128/JVI.76.21.10702-10707.2002
    • Kimura K, Kakimi K, Wieland S, et al. Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. J Virol 2002;76:10702-7. (Pubitemid 35176186)
    • (2002) Journal of Virology , vol.76 , Issue.21 , pp. 10702-10707
    • Kimura, K.1    Kakimi, K.2    Wieland, S.3    Guiotti, L.G.4    Chisari, F.V.5
  • 87
    • 33846085749 scopus 로고    scopus 로고
    • Immunopathogenesis of hepatitis B virus infection
    • DOI 10.1038/sj.icb.7100009, PII 7100009
    • Chang JJ, Lewin SR. Immunopathogenesis of hepatitis B virus infection. Immunol Cell Biol 2007;85:16-23. (Pubitemid 46067317)
    • (2007) Immunology and Cell Biology , vol.85 , Issue.1 , pp. 16-23
    • Chang, J.J.1    Lewin, S.R.2
  • 89
    • 84868702241 scopus 로고    scopus 로고
    • Innate and adaptive immune responses in chronic hepatitis B virus infections: Towards restoration of immune control of viral infection
    • Published Online First: 9 December doi:10.1136/gutjnl-2011-301073
    • Bertoletti A, Ferrari C. Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection. Gut. Published Online First: 9 December 2011. doi:10.1136/gutjnl- 2011-301073
    • (2011) Gut
    • Bertoletti, A.1    Ferrari, C.2
  • 90
    • 0036461318 scopus 로고    scopus 로고
    • Immunology of hepatitis B infection
    • DOI 10.1016/S1473-3099(01)00172-4
    • Jung MC, Pape GR. Immunology of hepatitis B infection. Lancet Infect Dis 2002;2:43-50. (Pubitemid 36109305)
    • (2002) Lancet Infectious Diseases , vol.2 , Issue.1 , pp. 43-50
    • Jung, M.-C.1    Pape, G.R.2
  • 91
    • 0030892283 scopus 로고    scopus 로고
    • Cytotoxic T cells and viral hepatitis
    • Chisari FV. Cytotoxic T cells and viral hepatitis. J Clin Invest 1997;99:1472-7. (Pubitemid 27163796)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.7 , pp. 1472-1477
    • Chisari, F.V.1
  • 92
    • 0035062597 scopus 로고    scopus 로고
    • Noncytolytic control of viral infections by the innate and adaptive immune response
    • DOI 10.1146/annurev.immunol.19.1.65
    • Guidotti LG, Chisari FV. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol 2001;19:65-91. (Pubitemid 32368030)
    • (2001) Annual Review of Immunology , vol.19 , pp. 65-91
    • Guidotti, L.G.1    Chisari, F.V.2
  • 93
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4:499-511. (Pubitemid 38931765)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 97
    • 59749098686 scopus 로고    scopus 로고
    • A mechanism to explain the selection of the hepatitis e antigen-negative mutant during chronic hepatitis B virus infection
    • Frelin L, Wahlstrom T, Tucker AE, et al. A mechanism to explain the selection of the hepatitis e antigen-negative mutant during chronic hepatitis B virus infection. J Virol 2009;83:1379-92.
    • (2009) J Virol , vol.83 , pp. 1379-1392
    • Frelin, L.1    Wahlstrom, T.2    Tucker, A.E.3
  • 99
    • 34247190634 scopus 로고    scopus 로고
    • Aberrant Epigenetic Modifications in Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
    • DOI 10.1053/j.gastro.2007.01.034, PII S0016508507001722
    • Park IY, Sohn BH, Yu E, et al. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology 2007;132:1476-94. (Pubitemid 46627570)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1476-1494
    • Park, I.Y.1    Sohn, B.H.2    Yu, E.3    Suh, D.J.4    Chung, Y.5    Lee, J.6    Surzycki, S.J.7    Lee, Y.I.8
  • 100
    • 77950787841 scopus 로고    scopus 로고
    • Hepatitis B virus replication induces methylation of both host and viral DNA
    • Vivekanandan P, Daniel HD, Kannangai R, et al. Hepatitis B virus replication induces methylation of both host and viral DNA. J Virol 2010;84:4321-9.
    • (2010) J Virol , vol.84 , pp. 4321-4329
    • Vivekanandan, P.1    Daniel, H.D.2    Kannangai, R.3
  • 101
    • 77955496554 scopus 로고    scopus 로고
    • The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein
    • Wei C, Ni C, Song T, et al. The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J Immunol 2010;185:1158-68.
    • (2010) J Immunol , vol.185 , pp. 1158-1168
    • Wei, C.1    Ni, C.2    Song, T.3
  • 102
    • 67650435788 scopus 로고    scopus 로고
    • HBsAg inhibits TLR9-mediated activation and IFN-alpha production in plasmacytoid dendritic cells
    • Xu Y, Hu Y, Shi B, et al. HBsAg inhibits TLR9-mediated activation and IFN-alpha production in plasmacytoid dendritic cells. Mol Immunol 2009;46:2640-6.
    • (2009) Mol Immunol , vol.46 , pp. 2640-2646
    • Xu, Y.1    Hu, Y.2    Shi, B.3
  • 103
    • 33746675024 scopus 로고    scopus 로고
    • Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study
    • DOI 10.1111/j.1572-0241.2006.00647.x
    • Chen G, Lin W, Shen F, et al. Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study. Am J Gastroenterol 2006;101:1797-803. (Pubitemid 44166589)
    • (2006) American Journal of Gastroenterology , vol.101 , Issue.8 , pp. 1797-1803
    • Chen, G.1    Lin, W.2    Shen, F.3    Iloeje, U.H.4    London, W.T.5    Evans, A.A.6
  • 104
    • 79551569966 scopus 로고    scopus 로고
    • Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression
    • Bar-Yishay I, Shaul Y, Shlomai A. Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression. Liver Int 2011;31:282-90.
    • (2011) Liver Int , vol.31 , pp. 282-290
    • Bar-Yishay, I.1    Shaul, Y.2    Shlomai, A.3
  • 105
    • 23044439383 scopus 로고    scopus 로고
    • cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV
    • DOI 10.1002/jmv.20427
    • Hajjou M, Norel R, Carver R, et al. cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV. J Med Virol 2005;77:57-65. (Pubitemid 41076477)
    • (2005) Journal of Medical Virology , vol.77 , Issue.1 , pp. 57-65
    • Hajjou, M.1    Norel, R.2    Carver, R.3    Marion, P.4    Cullen, J.5    Rogler, L.E.6    Rogler, C.E.7
  • 106
    • 34247637220 scopus 로고    scopus 로고
    • Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARgamma
    • DOI 10.1053/j.gastro.2007.03.039, PII S001650850700563X
    • Kim KH, Shin HJ, Kim K, et al. Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology 2007;132:1955-67. (Pubitemid 46677949)
    • (2007) Gastroenterology , vol.132 , Issue.5 , pp. 1955-1967
    • Kim, K.H.1    Shin, H.2    Kim, K.3    Choi, H.M.4    Rhee, S.H.5    Moon, H.6    Kim, H.H.7    Yang, U.S.8    Yu, D.9    Cheong, J.10
  • 107
    • 84855913126 scopus 로고    scopus 로고
    • The hepatitis B virus x protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake
    • Yang B, Bouchard MJ. The hepatitis B virus x protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake. J Virol 2012;86:313-27.
    • (2012) J Virol , vol.86 , pp. 313-327
    • Yang, B.1    Bouchard, M.J.2
  • 108
    • 16544364359 scopus 로고    scopus 로고
    • Inhibition of Cellular Proteasome Activities Enhances Hepadnavirus Replication in an HBX-Dependent Manner
    • DOI 10.1128/JVI.78.9.4566-4572.2004
    • Zhang Z, Protzer U, Hu Z, et al. Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner. J Virol 2004;78:4566-72. (Pubitemid 38501077)
    • (2004) Journal of Virology , vol.78 , Issue.9 , pp. 4566-4572
    • Zhang, Z.1    Protzer, U.2    Hu, Z.3    Jacob, J.4    Liang, T.J.5
  • 109
    • 33644854241 scopus 로고    scopus 로고
    • Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones
    • DOI 10.1053/j.gastro.2006.01.001, PII S0016508506000023
    • Pollicino T, Belloni L, Raffa G, et al. Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones. Gastroenterology 2006;130:823-37. (Pubitemid 43374531)
    • (2006) Gastroenterology , vol.130 , Issue.3 , pp. 823-837
    • Pollicino, T.1    Belloni, L.2    Raffa, G.3    Pediconi, N.4    Squadrito, G.5    Raimondo, G.6    Levrero, M.7
  • 110
    • 73949127893 scopus 로고    scopus 로고
    • Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
    • Belloni L, Pollicino T, De Nicola F, et al. Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function. Proc Natl Acad Sci U S A 2009;106:19975-9.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19975-19979
    • Belloni, L.1    Pollicino, T.2    De Nicola, F.3
  • 111
    • 80053994925 scopus 로고    scopus 로고
    • Replicative activity of hepatitis B virus is negatively associated with methylation of covalently closed circular DNA in advanced hepatitis B virus infection
    • Kim JW, Lee SH, Park YS, et al. Replicative activity of hepatitis B virus is negatively associated with methylation of covalently closed circular DNA in advanced hepatitis B virus infection. Intervirology 2011;54:316-25.
    • (2011) Intervirology , vol.54 , pp. 316-325
    • Kim, J.W.1    Lee, S.H.2    Park, Y.S.3
  • 112
    • 84984539055 scopus 로고    scopus 로고
    • Role of microRNAs in hepatitis B virus replication and pathogenesis
    • Liu WH, Yeh SH, Chen PJ. Role of microRNAs in hepatitis B virus replication and pathogenesis. Biochim Biophys Acta 2011;1809:678-85.
    • (2011) Biochim Biophys Acta , vol.1809 , pp. 678-685
    • Liu, W.H.1    Yeh, S.H.2    Chen, P.J.3
  • 113
    • 0028915795 scopus 로고
    • Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia
    • Thursz MR, Kwiatkowski D, Allsopp CE, et al. Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia. N Engl J Med 1995;332:1065-9.
    • (1995) N Engl J Med , vol.332 , pp. 1065-1069
    • Thursz, M.R.1    Kwiatkowski, D.2    Allsopp, C.E.3
  • 114
    • 79251473063 scopus 로고    scopus 로고
    • Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population
    • Guo X, Zhang Y, Li J, et al. Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population. Hepatology 2011;53:422-8.
    • (2011) Hepatology , vol.53 , pp. 422-428
    • Guo, X.1    Zhang, Y.2    Li, J.3
  • 116
    • 39749102982 scopus 로고    scopus 로고
    • Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers
    • Deng G, Zhou G, Zhang R, et al. Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers. Gastroenterology 2008;134:716-26.
    • (2008) Gastroenterology , vol.134 , pp. 716-726
    • Deng, G.1    Zhou, G.2    Zhang, R.3
  • 117
    • 3543081472 scopus 로고    scopus 로고
    • Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of lamivudine-resistant mutants
    • DOI 10.1128/JVI.78.16.8524-8535.2004
    • Tacke F, Gehrke C, Luedde T, et al. Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of Lamivudine-resistant mutants. J Virol 2004;78:8524-35. (Pubitemid 39025118)
    • (2004) Journal of Virology , vol.78 , Issue.16 , pp. 8524-8535
    • Tacke, F.1    Gehrke, C.2    Luedde, T.3    Heim, A.4    Manns, M.P.5    Trautwein, C.6
  • 118
    • 0027237797 scopus 로고
    • The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees
    • Ogata N, Miller RH, Ishak KG, et al. The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees. Virology 1993;194:263-76.
    • (1993) Virology , vol.194 , pp. 263-276
    • Ogata, N.1    Miller, R.H.2    Ishak, K.G.3
  • 119
    • 84984559412 scopus 로고    scopus 로고
    • Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers
    • Liu CJ, Chen BF, Chen PJ, et al. Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers. J Infect Dis 2006;193:1258-65.
    • (2006) J Infect Dis , vol.193 , pp. 1258-1265
    • Liu, C.J.1    Chen, B.F.2    Chen, P.J.3
  • 120
    • 33644792213 scopus 로고    scopus 로고
    • Longitudinal evaluation reveals a complex spectrum of virological profiles in hepatitis B virus/hepatitis C virus-coinfected patients
    • DOI 10.1002/hep.20944
    • Raimondo G, Brunetto MR, Pontisso P, et al. Longitudinal evaluation reveals a complex spectrum of virological profiles in hepatitis B virus/hepatitis C virus-coinfected patients. Hepatology 2006;43:100-7. (Pubitemid 43733596)
    • (2006) Hepatology , vol.43 , Issue.1 , pp. 100-107
    • Raimondo, G.1    Brunetto, M.R.2    Pontisso, P.3    Smedile, A.4    Maina, A.M.5    Saitta, C.6    Squadrito, G.7    Tono, N.8
  • 121
    • 0034920697 scopus 로고    scopus 로고
    • Role of hepatitis B, C, and D viruses in dual and triple infection: Influence of viral genotypes and hepatitis B precore and basal core promoter mutations on viral replicative interference
    • DOI 10.1053/jhep.2001.26511
    • Jardi R, Rodriguez F, Buti M, et al. Role of hepatitis B, C, and D viruses in dual and triple infection: influence of viral genotypes and hepatitis B precore and basal core promoter mutations on viral replicative interference. Hepatology 2001;34:404-10. (Pubitemid 32702354)
    • (2001) Hepatology , vol.34 , Issue.2 , pp. 404-410
    • Jardi, R.1    Rodriguez, F.2    Buti, M.3    Costa, X.4    Cotrina, M.5    Galimany, R.6    Esteban, R.7    Guardia, J.8
  • 122
    • 79955445363 scopus 로고    scopus 로고
    • Clinical outcome of acute and chronic hepatitis delta over time: A long-term follow-up study
    • Buti M, Homs M, Rodriguez-Frias F, et al. Clinical outcome of acute and chronic hepatitis delta over time: a long-term follow-up study. J Viral Hepat 2011;18:434-42.
    • (2011) J Viral Hepat , vol.18 , pp. 434-442
    • Buti, M.1    Homs, M.2    Rodriguez-Frias, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.