메뉴 건너뛰기




Volumn 48, Issue 1, 2008, Pages 88-98

The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; DIHYDROLIPOAMIDE DEHYDROGENASE; GLYCOSYLATED ALBUMIN; LAMIVUDINE; MEMBRANE PROTEIN; VIRUS DNA; VITRONECTIN;

EID: 47149111970     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22295     Document Type: Article
Times cited : (212)

References (37)
  • 1
    • 0031612751 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen and polymerase gene variants: Potential virological and clinical significance
    • Locarnini SA. Hepatitis B virus surface antigen and polymerase gene variants: potential virological and clinical significance. HEPATOLOGY 1998;27:294-297.
    • (1998) HEPATOLOGY , vol.27 , pp. 294-297
    • Locarnini, S.A.1
  • 3
    • 33750588091 scopus 로고    scopus 로고
    • Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif
    • Yatsuji H, Noguchi C, Hiraga N, Mori N, Tsuge M, Imamura M, et al. Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif. Antimicrob Agents Chemother 2006;50:3867-3874.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 3867-3874
    • Yatsuji, H.1    Noguchi, C.2    Hiraga, N.3    Mori, N.4    Tsuge, M.5    Imamura, M.6
  • 4
    • 0034040297 scopus 로고    scopus 로고
    • Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy
    • Yeh CT, Chien RN, Chu CM, Liaw YF. Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy. HEPATOLOGY 2000;31:1318-1326.
    • (2000) HEPATOLOGY , vol.31 , pp. 1318-1326
    • Yeh, C.T.1    Chien, R.N.2    Chu, C.M.3    Liaw, Y.F.4
  • 5
    • 34248668494 scopus 로고    scopus 로고
    • Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B
    • Yoo BC, Kim JH, Chung YH, Lee KS, Paik SW, Ryu SH, et al. Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B. HEPATOLOGY 2007;45:1172-1178.
    • (2007) HEPATOLOGY , vol.45 , pp. 1172-1178
    • Yoo, B.C.1    Kim, J.H.2    Chung, Y.H.3    Lee, K.S.4    Paik, S.W.5    Ryu, S.H.6
  • 6
    • 34249075512 scopus 로고    scopus 로고
    • In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents
    • Qi X, Xiong S, Yang H, Miller M, Delaney WEI. In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents. Antivir Ther 2007;12:355-362.
    • (2007) Antivir Ther , vol.12 , pp. 355-362
    • Qi, X.1    Xiong, S.2    Yang, H.3    Miller, M.4    Delaney, W.E.I.5
  • 7
    • 0025770151 scopus 로고
    • Mutational analysis of hepatitis B surface antigen particle assembly and secretion
    • Bruss V, Ganem D. Mutational analysis of hepatitis B surface antigen particle assembly and secretion. J Virol 1991;65:3813-3820.
    • (1991) J Virol , vol.65 , pp. 3813-3820
    • Bruss, V.1    Ganem, D.2
  • 8
    • 0033014227 scopus 로고    scopus 로고
    • Mutations in the carboxyl-terminal domain of the small hepatitis B virus envelope protein impair the assembly of hepatitis delta virus particles
    • Jenna S, Sureau C. Mutations in the carboxyl-terminal domain of the small hepatitis B virus envelope protein impair the assembly of hepatitis delta virus particles. J Virol 1999;73:3351-3358.
    • (1999) J Virol , vol.73 , pp. 3351-3358
    • Jenna, S.1    Sureau, C.2
  • 9
    • 34247191982 scopus 로고    scopus 로고
    • SEQHEPB: A sequence analysis program and relational database system for chronic hepatitis B
    • Yuen LK, Ayres A, Littlejohn M, Colledge D, Edgely A, Maskill WJ, et al. SEQHEPB: a sequence analysis program and relational database system for chronic hepatitis B. Antiviral Res 2007;75:64-74.
    • (2007) Antiviral Res , vol.75 , pp. 64-74
    • Yuen, L.K.1    Ayres, A.2    Littlejohn, M.3    Colledge, D.4    Edgely, A.5    Maskill, W.J.6
  • 10
    • 34447255407 scopus 로고    scopus 로고
    • The rtL80I substitution in the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro
    • Warner N, Locarnini S, Kuiper M, Bartholomeusz A, Ayres A, Yuen L, et al. The rtL80I substitution in the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro. Antimicrob Agents Chemother 2007;51:2285-2292.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 2285-2292
    • Warner, N.1    Locarnini, S.2    Kuiper, M.3    Bartholomeusz, A.4    Ayres, A.5    Yuen, L.6
  • 11
    • 0037221770 scopus 로고    scopus 로고
    • Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro
    • Chen RY, Edwards R, Shaw T, Colledge D, Delaney WE 4th, Isom H, et al. Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro. HEPATOLOGY 2003;37:27-35.
    • (2003) HEPATOLOGY , vol.37 , pp. 27-35
    • Chen, R.Y.1    Edwards, R.2    Shaw, T.3    Colledge, D.4    Delaney 4th, W.E.5    Isom, H.6
  • 12
    • 0032804970 scopus 로고    scopus 로고
    • Immunoassay detection of hepatitis B surface antigen mutants
    • Coleman PF, Chen YC, Mushahwar IK. Immunoassay detection of hepatitis B surface antigen mutants. J Med Virol 1999;59:19-24.
    • (1999) J Med Virol , vol.59 , pp. 19-24
    • Coleman, P.F.1    Chen, Y.C.2    Mushahwar, I.K.3
  • 13
    • 0033840084 scopus 로고    scopus 로고
    • Preclinical evaluation of two human anti-hepatitis B virus (HBV) monoclonal antibodies in the HBV-trimera mouse model and in HBV chronic carrier chimpanzees
    • Eren R, Ilan E, Nussbaum O, Lubin I, Terkieltaub D, Arazi Y, et al. Preclinical evaluation of two human anti-hepatitis B virus (HBV) monoclonal antibodies in the HBV-trimera mouse model and in HBV chronic carrier chimpanzees. HEPATOLOGY 2000;32:588-596.
    • (2000) HEPATOLOGY , vol.32 , pp. 588-596
    • Eren, R.1    Ilan, E.2    Nussbaum, O.3    Lubin, I.4    Terkieltaub, D.5    Arazi, Y.6
  • 14
    • 2642562930 scopus 로고    scopus 로고
    • Processing of hepatitis B virus surface proteins
    • Bruss V. Processing of hepatitis B virus surface proteins. Methods Mol Med 2004;95:189-198.
    • (2004) Methods Mol Med , vol.95 , pp. 189-198
    • Bruss, V.1
  • 15
    • 0026808738 scopus 로고
    • The heparitis B virus pre-S/S(t) transactivator is generated by 3′ truncations within a defined region of the S gene
    • Lauer U, Weiss L, Hofschneider PH, Kekule AS. The heparitis B virus pre-S/S(t) transactivator is generated by 3′ truncations within a defined region of the S gene. J Virol 1992;66:5284-5289.
    • (1992) J Virol , vol.66 , pp. 5284-5289
    • Lauer, U.1    Weiss, L.2    Hofschneider, P.H.3    Kekule, A.S.4
  • 16
    • 0026588451 scopus 로고
    • Characterization of the hepatitis B virus preS/S region encoded transcriptional transactivator
    • Natoli G, Avantaggiati ML, Balsano C, De Marzio E, Collepardo D, Elfassi E, et al. Characterization of the hepatitis B virus preS/S region encoded transcriptional transactivator. Virology 1992;187:663-670.
    • (1992) Virology , vol.187 , pp. 663-670
    • Natoli, G.1    Avantaggiati, M.L.2    Balsano, C.3    De Marzio, E.4    Collepardo, D.5    Elfassi, E.6
  • 17
    • 30344458192 scopus 로고    scopus 로고
    • Cellular and virological mechanisms of HBV drug resistance
    • Locarnini S, Mason WS. Cellular and virological mechanisms of HBV drug resistance. J Hepatol 2006;44:422-431.
    • (2006) J Hepatol , vol.44 , pp. 422-431
    • Locarnini, S.1    Mason, W.S.2
  • 19
    • 0033761078 scopus 로고    scopus 로고
    • Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B
    • Si Ahmed S, Tavan D, Pichoud C, Berby F, Stuyver L, Johnson M, et al. Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. HEPATOLOGY 2000;32:1078-1088.
    • (2000) HEPATOLOGY , vol.32 , pp. 1078-1088
    • Si Ahmed, S.1    Tavan, D.2    Pichoud, C.3    Berby, F.4    Stuyver, L.5    Johnson, M.6
  • 20
    • 0034814179 scopus 로고    scopus 로고
    • Evaluation of novel strategies to combat hepatitis B virus targetting wild-type and drug-resistant mutants in experimental models
    • Zoulim F. Evaluation of novel strategies to combat hepatitis B virus targetting wild-type and drug-resistant mutants in experimental models. Antivir Chem Chemother 2001;12(Suppl 1):131-142.
    • (2001) Antivir Chem Chemother , vol.12 , Issue.SUPPL. 1 , pp. 131-142
    • Zoulim, F.1
  • 21
    • 0034802516 scopus 로고    scopus 로고
    • Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
    • Yuen MF, Sablon E, Hui CK, Yuan HJ, Decraemer H, Lai CL. Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy. HEPATOLOGY 2001;34:785-791.
    • (2001) HEPATOLOGY , vol.34 , pp. 785-791
    • Yuen, M.F.1    Sablon, E.2    Hui, C.K.3    Yuan, H.J.4    Decraemer, H.5    Lai, C.L.6
  • 22
    • 0041853784 scopus 로고    scopus 로고
    • Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase
    • Angus P, Vaughan R, Xiong S, Yang H, Delaney W, Gibbs C, et al. Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase. Gastroenterology 2003;125:292-297.
    • (2003) Gastroenterology , vol.125 , pp. 292-297
    • Angus, P.1    Vaughan, R.2    Xiong, S.3    Yang, H.4    Delaney, W.5    Gibbs, C.6
  • 23
    • 34547425435 scopus 로고    scopus 로고
    • Antiviral drug-resistant HBV: Standardization of nomenclature and assays and recommendations for management
    • Lok AS, Zoulim F, Locarnini S, Bartholomeusz A, Ghany MG, Pawlotsky JM, et al. Antiviral drug-resistant HBV: standardization of nomenclature and assays and recommendations for management. HEPATOLOGY 2007;46:254-265.
    • (2007) HEPATOLOGY , vol.46 , pp. 254-265
    • Lok, A.S.1    Zoulim, F.2    Locarnini, S.3    Bartholomeusz, A.4    Ghany, M.G.5    Pawlotsky, J.M.6
  • 25
    • 0029787759 scopus 로고    scopus 로고
    • Characterization of early hepatitis B virus surface protein oligomers
    • Wunderlich G, Bruss V. Characterization of early hepatitis B virus surface protein oligomers. Arch Virol 1996;141:1191-1205.
    • (1996) Arch Virol , vol.141 , pp. 1191-1205
    • Wunderlich, G.1    Bruss, V.2
  • 27
    • 0026034960 scopus 로고
    • The role of envelope proteins in hepatitis B virus assembly
    • Bruss V, Ganem D. The role of envelope proteins in hepatitis B virus assembly. Proc Natl Acad Sci U S A 1991;88:1059-1063.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 1059-1063
    • Bruss, V.1    Ganem, D.2
  • 28
    • 0028874697 scopus 로고
    • Functions of the internal pre-S domain of the large surface protein in hepatitis B virus particle morphogenesis
    • Bruss V, Vieluf K. Functions of the internal pre-S domain of the large surface protein in hepatitis B virus particle morphogenesis. J Virol 1995;69:6652-6657.
    • (1995) J Virol , vol.69 , pp. 6652-6657
    • Bruss, V.1    Vieluf, K.2
  • 29
    • 26444569334 scopus 로고    scopus 로고
    • Heparitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme
    • Simsek E, Mehta A, Zhou T, Dwek RA, Block T. Heparitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme. J Virol 2005;79:12914-12920.
    • (2005) J Virol , vol.79 , pp. 12914-12920
    • Simsek, E.1    Mehta, A.2    Zhou, T.3    Dwek, R.A.4    Block, T.5
  • 30
    • 33749394947 scopus 로고    scopus 로고
    • Rost M, Mann S, Lambert C, Doring T, Thome N, Prange R. Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. J Biol Chem 2006;281:29297-29308.
    • Rost M, Mann S, Lambert C, Doring T, Thome N, Prange R. Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. J Biol Chem 2006;281:29297-29308.
  • 32
    • 0031058830 scopus 로고    scopus 로고
    • Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion
    • Mehta A, Lu X, Block TM, Blumberg BS, Dwek RA. Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion. Proc Natl Acad Sci U S A 1997;94:1822-1827.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1822-1827
    • Mehta, A.1    Lu, X.2    Block, T.M.3    Blumberg, B.S.4    Dwek, R.A.5
  • 33
    • 0030964918 scopus 로고    scopus 로고
    • Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited
    • Lu X, Mehta A, Dadmarz M, Dwek R, Blumberg BS, Block TM. Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited. Proc Natl Acad Sci U S A 1997;94:2380-2385.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2380-2385
    • Lu, X.1    Mehta, A.2    Dadmarz, M.3    Dwek, R.4    Blumberg, B.S.5    Block, T.M.6
  • 34
    • 0028872090 scopus 로고
    • Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion
    • Lu X, Mehta A, Dwek R, Butters T, Block T. Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion. Virology 1995; 213:660-665.
    • (1995) Virology , vol.213 , pp. 660-665
    • Lu, X.1    Mehta, A.2    Dwek, R.3    Butters, T.4    Block, T.5
  • 35
    • 0037404556 scopus 로고    scopus 로고
    • Role of N glycosylation of hepatitis B virus envelope proteins in morphogenesis and infectivity of hepatitis delta virus
    • Sureau C, Fournier-Wirth C, Maurel P. Role of N glycosylation of hepatitis B virus envelope proteins in morphogenesis and infectivity of hepatitis delta virus. J Virol 2003;77:5519-5523.
    • (2003) J Virol , vol.77 , pp. 5519-5523
    • Sureau, C.1    Fournier-Wirth, C.2    Maurel, P.3
  • 36
    • 84984537250 scopus 로고    scopus 로고
    • N-linked glycosylation of hepatitis B surface antigens is involved but not essential in the assembly of hepatitis delta virus
    • Wang CJ, Sung SY, Chen DS, Chen PJ. N-linked glycosylation of hepatitis B surface antigens is involved but not essential in the assembly of hepatitis delta virus. Virology 1996;220:28-36.
    • (1996) Virology , vol.220 , pp. 28-36
    • Wang, C.J.1    Sung, S.Y.2    Chen, D.S.3    Chen, P.J.4
  • 37
    • 34250351769 scopus 로고    scopus 로고
    • Posttranslational N-glycosylation of the hepatitis B virus large envelope protein
    • Lambert C, Prange R. Posttranslational N-glycosylation of the hepatitis B virus large envelope protein. Virol J 2007;4:45.
    • Virol , vol.J 2007 , Issue.4 , pp. 45
    • Lambert, C.1    Prange, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.