Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site

Journal of Virology

Volumn 84, Issue 24, 2010, Pages 12850-12861

  Ito, Kiyoaki ^a,b   Qin, Yanli ^a,c   Guarnieri, Michael ^a,d   Garcia, Tamako ^a,e   Kwei, Karen ^a,f   Mizokami, Masashi ^b   Zhang, Jiming ^c   Li, Jisu ^a   Wands, Jack R ^a   Tong, Shuping ^a  

^a BROWN UNIVERSITY   (United States)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; TUNICAMYCIN; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ANTIGEN DETECTION; ARTICLE; GENE MUTATION; GENETIC TRANSFECTION; GLYCOSYLATION; HEPATITIS B VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRION; WILD TYPE;

ALKALINE PHOSPHATASE; AMINO ACID SUBSTITUTION; BLOTTING, WESTERN; DNA REPLICATION; GENOTYPE; GLYCOSYLATION; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENOTYPE; PROTEIN PRECURSORS; VIRAL ENVELOPE PROTEINS; VIRION; VIRUS REPLICATION;

HEPATITIS B VIRUS;

EID: 78649413761     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01499-10     Document Type: Article

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