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Volumn 44, Issue 3, 2006, Pages 694-702

Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; RNA;

EID: 33748939050     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21299     Document Type: Article
Times cited : (170)

References (44)
  • 1
    • 0001765014 scopus 로고
    • Hepatitis B e antigen negative chronic hepatitis B: From clinical recognition to pathogenesis and treatment
    • Hadziyannis SJ. Hepatitis B e antigen negative chronic hepatitis B: from clinical recognition to pathogenesis and treatment. Viral Hepat Rev 1995;1:7-36.
    • (1995) Viral Hepat Rev , vol.1 , pp. 7-36
    • Hadziyannis, S.J.1
  • 2
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Lee WM. Hepatitis B virus infection. N Engl J Med 1997;337:1733-1745.
    • (1997) N Engl J Med , vol.337 , pp. 1733-1745
    • Lee, W.M.1
  • 3
    • 0035189597 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok AS, McMahon BJ. Chronic hepatitis B. HEPATOLOGY 2001;34:1225-1241.
    • (2001) Hepatology , vol.34 , pp. 1225-1241
    • Lok, A.S.1    McMahon, B.J.2
  • 4
    • 0030225455 scopus 로고    scopus 로고
    • Hepatitis B virus replication - An update
    • Nassal M, Schaller H. Hepatitis B virus replication-an update. J Viral Hepat 1996;3:217-226.
    • (1996) J Viral Hepat , vol.3 , pp. 217-226
    • Nassal, M.1    Schaller, H.2
  • 6
    • 0019949367 scopus 로고
    • Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate
    • Summers J, Mason WS. Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate. Cell 1982;29:403-415.
    • (1982) Cell , vol.29 , pp. 403-415
    • Summers, J.1    Mason, W.S.2
  • 7
    • 0028095561 scopus 로고
    • Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell
    • Bock CT, Schranz P, Schroder CH, Zentgraf H. Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell. Virus Genes 1994;8:215-229.
    • (1994) Virus Genes , vol.8 , pp. 215-229
    • Bock, C.T.1    Schranz, P.2    Schroder, C.H.3    Zentgraf, H.4
  • 8
    • 0029037074 scopus 로고
    • The covalently dosed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S, et al. The covalently dosed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol 1995;69:3350-3357.
    • (1995) J Virol , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3    Sherman, G.4    Dean, J.5    Bowden, S.6
  • 9
    • 0023028191 scopus 로고
    • Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells
    • Tuttleman JS, Pourcel C, Summers J. Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell 1986;47:451-460.
    • (1986) Cell , vol.47 , pp. 451-460
    • Tuttleman, J.S.1    Pourcel, C.2    Summers, J.3
  • 10
    • 0032731871 scopus 로고    scopus 로고
    • The core promoter of hepatitis B virus
    • Kramvis A, Kew MC. The core promoter of hepatitis B virus. J Viral Hepat 1999;6:415-427.
    • (1999) J Viral Hepat , vol.6 , pp. 415-427
    • Kramvis, A.1    Kew, M.C.2
  • 11
    • 0345212927 scopus 로고
    • Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA
    • Yaginuma K, Shirakata Y, Kobayashi M, Koike K. Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA. Proc Natl Acad Sci U S A 1987;84:2678-2682.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 2678-2682
    • Yaginuma, K.1    Shirakata, Y.2    Kobayashi, M.3    Koike, K.4
  • 13
    • 0026052737 scopus 로고
    • Molecular heterogeneity of e antigen polypeptides in sera from carriers of hepatitis B virus
    • Takahashi K, Kishimoto S, Ohori K, Yoshizawa H, Machida A, Ohnuma H, et al. Molecular heterogeneity of e antigen polypeptides in sera from carriers of hepatitis B virus. J Immunol 1991;147:3156-3160.
    • (1991) J Immunol , vol.147 , pp. 3156-3160
    • Takahashi, K.1    Kishimoto, S.2    Ohori, K.3    Yoshizawa, H.4    Machida, A.5    Ohnuma, H.6
  • 14
    • 0025329760 scopus 로고
    • In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway
    • Wu TT, Coates L, Aldrich CE, Summers J, Mason WS. In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway. Virology 1990;175:255-261.
    • (1990) Virology , vol.175 , pp. 255-261
    • Wu, T.T.1    Coates, L.2    Aldrich, C.E.3    Summers, J.4    Mason, W.S.5
  • 15
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, Makris A, et al. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989;2:588-591.
    • (1989) Lancet , vol.2 , pp. 588-591
    • Carman, W.F.1    Jacyna, M.R.2    Hadziyannis, S.3    Karayiannis, P.4    McGarvey, M.J.5    Makris, A.6
  • 18
    • 0036902495 scopus 로고    scopus 로고
    • World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated pre-core and core promoter variants
    • Funk ML, Rosenberg DM, Lok AS. World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated pre-core and core promoter variants. J Viral Hepat 2002;9:52-61.
    • (2002) J Viral Hepat , vol.9 , pp. 52-61
    • Funk, M.L.1    Rosenberg, D.M.2    Lok, A.S.3
  • 19
    • 0034802538 scopus 로고    scopus 로고
    • Hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Vassilopoulos D. Hepatitis B e antigen-negative chronic hepatitis B. HEPATOLOGY 2001;34:617-624.
    • (2001) Hepatology , vol.34 , pp. 617-624
    • Hadziyannis, S.J.1    Vassilopoulos, D.2
  • 20
    • 0029817029 scopus 로고    scopus 로고
    • Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication
    • Buckwold VE, Xu Z, Chen M, Yen TS, Ou JH. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol 1996;70:5845-5851.
    • (1996) J Virol , vol.70 , pp. 5845-5851
    • Buckwold, V.E.1    Xu, Z.2    Chen, M.3    Yen, T.S.4    Ou, J.H.5
  • 21
    • 0031984485 scopus 로고    scopus 로고
    • Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) → T, A(1762) → T and G(1764) → a mutations in the core promoter
    • Gunther S, Piwon N, Will H. Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) → T, A(1762) → T and G(1764) → A mutations in the core promoter. J Gen Virol 1998;79(Pt 2):375-380.
    • (1998) J Gen Virol , vol.79 , Issue.PART 2 , pp. 375-380
    • Gunther, S.1    Piwon, N.2    Will, H.3
  • 22
    • 0036058945 scopus 로고    scopus 로고
    • In vivo suppression of precore mRNA synthesis is associated with mutations in the hepatitis B virus core promoter
    • Laras A, Koskinas J, Hadziyannis SJ. In vivo suppression of precore mRNA synthesis is associated with mutations in the hepatitis B virus core promoter. Virology 2002;295:86-96.
    • (2002) Virology , vol.295 , pp. 86-96
    • Laras, A.1    Koskinas, J.2    Hadziyannis, S.J.3
  • 23
    • 0030589455 scopus 로고    scopus 로고
    • Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections
    • Moriyama K, Okamoto H, Tsuda F, Mayumi M. Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections. Virology 1996;226:269-280.
    • (1996) Virology , vol.226 , pp. 269-280
    • Moriyama, K.1    Okamoto, H.2    Tsuda, F.3    Mayumi, M.4
  • 24
    • 0021934431 scopus 로고
    • Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: Analysis of intrahepatic replicative hepatitis B virus DNA
    • Yokosuka O, Omata M, Imazeki F, Okuda K, Summers J. Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: analysis of intrahepatic replicative hepatitis B virus DNA. HEPATOLOGY 1985;5:728-734.
    • (1985) Hepatology , vol.5 , pp. 728-734
    • Yokosuka, O.1    Omata, M.2    Imazeki, F.3    Okuda, K.4    Summers, J.5
  • 25
    • 0028053046 scopus 로고
    • Characterization of the antiviral effects of 2′ carbodeoxyguanosine in ducks chronically infected with duck hepatitis B virus
    • Mason WS, Cullen J, Saputelli J, Wu TT, Liu C, London WT, et al. Characterization of the antiviral effects of 2′ carbodeoxyguanosine in ducks chronically infected with duck hepatitis B virus. HEPATOLOGY 1994;19:398-411.
    • (1994) Hepatology , vol.19 , pp. 398-411
    • Mason, W.S.1    Cullen, J.2    Saputelli, J.3    Wu, T.T.4    Liu, C.5    London, W.T.6
  • 26
    • 0029786431 scopus 로고    scopus 로고
    • Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: Effect on intrahepatic-viral DNA, RNA, and protein expression
    • Luscombe C, Pedersen J, Uren E, Locarnini S. Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: effect on intrahepatic-viral DNA, RNA, and protein expression. HEPATOLOGY 1996;24:766-773.
    • (1996) Hepatology , vol.24 , pp. 766-773
    • Luscombe, C.1    Pedersen, J.2    Uren, E.3    Locarnini, S.4
  • 27
    • 0037221770 scopus 로고    scopus 로고
    • Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro
    • Chen RY, Edwards R, Shaw T, Colledge D, Delaney WE, Isom H, et al. Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro. HEPATOLOGY 2003;37:27-35.
    • (2003) Hepatology , vol.37 , pp. 27-35
    • Chen, R.Y.1    Edwards, R.2    Shaw, T.3    Colledge, D.4    Delaney, W.E.5    Isom, H.6
  • 28
    • 3543081472 scopus 로고    scopus 로고
    • Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of Lamivudine-resistant mutants
    • Tacke F, Gehrke C, Luedde T, Heim A, Manns MP, Trautwein C. Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of Lamivudine-resistant mutants. J Virol 2004;78:8524-8535.
    • (2004) J Virol , vol.78 , pp. 8524-8535
    • Tacke, F.1    Gehrke, C.2    Luedde, T.3    Heim, A.4    Manns, M.P.5    Trautwein, C.6
  • 29
    • 0033751024 scopus 로고    scopus 로고
    • A quantitative competitive PCR assay for the covalently closed circular form of the duck hepatitis B virus
    • Addison WR, Wong WW, Fischer KP, Tyrrell DL. A quantitative competitive PCR assay for the covalently closed circular form of the duck hepatitis B virus. Antiviral Res 2000;48:27-37.
    • (2000) Antiviral Res , vol.48 , pp. 27-37
    • Addison, W.R.1    Wong, W.W.2    Fischer, K.P.3    Tyrrell, D.L.4
  • 30
    • 0036343697 scopus 로고    scopus 로고
    • A new and sensitive method for the quantification of HBV cccDNA by real-time PCR
    • He ML, Wu J, Chen Y, Lin MC, Lau GK, Kung HF. A new and sensitive method for the quantification of HBV cccDNA by real-time PCR. Biochem Biophys Res Commun 2002;295:1102-1107.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 1102-1107
    • He, M.L.1    Wu, J.2    Chen, Y.3    Lin, M.C.4    Lau, G.K.5    Kung, H.F.6
  • 31
    • 0242285751 scopus 로고    scopus 로고
    • A quantitative method to detect HBV cccDNA by chimeric primer and real-time polymerase chain reaction
    • Jun-Bin S, Zhi C, Wei-Qin N, Jun F. A quantitative method to detect HBV cccDNA by chimeric primer and real-time polymerase chain reaction. J Virol Methods 2003;112:45-52.
    • (2003) J Virol Methods , vol.112 , pp. 45-52
    • Jun-Bin, S.1    Zhi, C.2    Wei-Qin, N.3    Jun, F.4
  • 32
    • 1842735646 scopus 로고    scopus 로고
    • Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR
    • Singh M, Dicaire A, Wakil AE, Luscombe C, Sacks SL. Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR. J Virol Methods 2004;118:159-167.
    • (2004) J Virol Methods , vol.118 , pp. 159-167
    • Singh, M.1    Dicaire, A.2    Wakil, A.E.3    Luscombe, C.4    Sacks, S.L.5
  • 33
    • 4644296081 scopus 로고    scopus 로고
    • Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients
    • Wong DK, Yuen MF, Yuan H, Sum SS, Hui CK, Hall J, et al. Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients. HEPATOLOGY 2004;40:727-737.
    • (2004) Hepatology , vol.40 , pp. 727-737
    • Wong, D.K.1    Yuen, M.F.2    Yuan, H.3    Sum, S.S.4    Hui, C.K.5    Hall, J.6
  • 34
    • 2942532722 scopus 로고    scopus 로고
    • Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
    • Werle-Lapostolle B, Bowden S, Locarnini S, Wursthorn K, Petersen J, Lau G, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004;126:1750-1758.
    • (2004) Gastroenterology , vol.126 , pp. 1750-1758
    • Werle-Lapostolle, B.1    Bowden, S.2    Locarnini, S.3    Wursthorn, K.4    Petersen, J.5    Lau, G.6
  • 35
    • 20444505037 scopus 로고    scopus 로고
    • Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
    • Sung JJ, Wong ML, Bowden S, Liew CT, Hui AY, Wong VW, et al. Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 2005;128:1890-1897.
    • (2005) Gastroenterology , vol.128 , pp. 1890-1897
    • Sung, J.J.1    Wong, M.L.2    Bowden, S.3    Liew, C.T.4    Hui, A.Y.5    Wong, V.W.6
  • 36
    • 0036109092 scopus 로고    scopus 로고
    • Half-life of the duck hepatitis B virus covalently closed circular DNA pool in vivo following inhibition of viral replication
    • Addison WR, Walters KA, Wong WW, Wilson JS, Madej D, Jewell LD, et al. Half-life of the duck hepatitis B virus covalently closed circular DNA pool in vivo following inhibition of viral replication. J Virol 2002;76:6356-6363.
    • (2002) J Virol , vol.76 , pp. 6356-6363
    • Addison, W.R.1    Walters, K.A.2    Wong, W.W.3    Wilson, J.S.4    Madej, D.5    Jewell, L.D.6
  • 38
    • 0142027756 scopus 로고    scopus 로고
    • Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver
    • Zhang YY, Zhang BH, Theele D, Litwin S, Toll E, Summers J. Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver. Proc Natl Acad Sci U S A 2003;100:12372-12377.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12372-12377
    • Zhang, Y.Y.1    Zhang, B.H.2    Theele, D.3    Litwin, S.4    Toll, E.5    Summers, J.6
  • 39
    • 0034749753 scopus 로고    scopus 로고
    • Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis
    • Zhu Y, Yamamoto T, Cullen J, Saputelli J, Aldrich CE, Miller DS, et al. Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J Virol 2001;75:311-322.
    • (2001) J Virol , vol.75 , pp. 311-322
    • Zhu, Y.1    Yamamoto, T.2    Cullen, J.3    Saputelli, J.4    Aldrich, C.E.5    Miller, D.S.6
  • 41
    • 0034777487 scopus 로고    scopus 로고
    • Circulating hepatitis B virus nucleic acids in chronic infection: Representation of differently polyadenylated viral transcripts during progression to nonreplicative stages
    • Su Q, Wang SF, Chang TE, Breitkreutz R, Hennig H, Takegoshi K, et al. Circulating hepatitis B virus nucleic acids in chronic infection: representation of differently polyadenylated viral transcripts during progression to nonreplicative stages. Clin Cancer Res 2001;7:2005-2015.
    • (2001) Clin Cancer Res , vol.7 , pp. 2005-2015
    • Su, Q.1    Wang, S.F.2    Chang, T.E.3    Breitkreutz, R.4    Hennig, H.5    Takegoshi, K.6
  • 42
    • 0141459381 scopus 로고    scopus 로고
    • Patterns of circulating hepatitis B virus serum nucleic acids during lamivudine therapy
    • Zhang W, Hacker HJ, Tokus M, Bock T, Schroder CH. Patterns of circulating hepatitis B virus serum nucleic acids during lamivudine therapy. J Med Virol 2003;71:24-30.
    • (2003) J Med Virol , vol.71 , pp. 24-30
    • Zhang, W.1    Hacker, H.J.2    Tokus, M.3    Bock, T.4    Schroder, C.H.5
  • 43
    • 0025334855 scopus 로고
    • Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification
    • Summers J, Smith PM, Horwich AL. Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification. J Virol 1990;64:2819-2824.
    • (1990) J Virol , vol.64 , pp. 2819-2824
    • Summers, J.1    Smith, P.M.2    Horwich, A.L.3
  • 44
    • 0028145857 scopus 로고
    • Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes
    • Lenhoff RJ, Summers J. Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes. J Virol 1994;68:5706-5713.
    • (1994) J Virol , vol.68 , pp. 5706-5713
    • Lenhoff, R.J.1    Summers, J.2


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