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Volumn 55, Issue 5, 2011, Pages 1121-1131

Hepatitis B surface antigen quantification: Why and how to use it in 2011 - A core group report

(13)  Chan, Henry Lik Yuen a   Thompson, Alex b   Martinot Peignoux, Michelle c   Piratvisuth, Teerha d   Cornberg, Markus e   Brunetto, Maurizia Rossana f   Tillmann, Hans L g   Kao, Jia Horng h   Jia, Ji Dong i   Wedemeyer, Heiner e   Locarnini, Stephen b   Janssen, Harry L A j   Marcellin, Patrick c  


Author keywords

Antiviral treatment; HBsAg; Hepatitis B virus; Peginterferon

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; CIRCULAR DNA; ENTECAVIR; GENOMIC RNA; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; NUCLEOSIDE ANALOG; PEGINTERFERON; PEGINTERFERON ALPHA2A; TELBIVUDINE; TENOFOVIR; VIRUS DNA;

EID: 80054724912     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.06.006     Document Type: Review
Times cited : (279)

References (85)
  • 1
    • 0014376546 scopus 로고
    • Hepatitis and leukemia: Their relation to Australia antigen
    • B.S. Blumberg, A.I. Sutnick, and W.T. London Hepatitis and leukemia: their relation to Australia antigen Bull NY Acad Med 44 1968 1566 1586
    • (1968) Bull NY Acad Med , vol.44 , pp. 1566-1586
    • Blumberg, B.S.1    Sutnick, A.I.2    London, W.T.3
  • 2
    • 0020323072 scopus 로고
    • Diagnostic significance of quantitative determination of hepatitis B surface antigen in acute and chronic hepatitis B infection
    • G.G. Frosner, H. Schomerus, and K.H. Wiedmann Diagnostic significance of quantitative determination of hepatitis B surface antigen in acute and chronic hepatitis B infection Eur J Clin Microbiol 1 1982 52 58 (Pubitemid 12025122)
    • (1982) European Journal of Clinical Microbiology , vol.1 , Issue.1 , pp. 52-58
    • Frosner, G.G.1    Schomerus, H.2    Wiedmann, K.H.3
  • 4
    • 72949088565 scopus 로고    scopus 로고
    • Use of the Elecysys HBsAg II assay for simple and accurate quantification of HBsAg levels in sera of patients infected with HBV
    • F. Bonino, M.R. Brunetto, P. Colombatto, F. Moriconi, E. Torresani, and G. Lunghi Use of the Elecysys HBsAg II assay for simple and accurate quantification of HBsAg levels in sera of patients infected with HBV Hepatol Int 3 2009 108
    • (2009) Hepatol Int , vol.3 , pp. 108
    • Bonino, F.1    Brunetto, M.R.2    Colombatto, P.3    Moriconi, F.4    Torresani, E.5    Lunghi, G.6
  • 6
    • 36549058611 scopus 로고    scopus 로고
    • Serum Hepatitis B Surface Antigen Quantitation Can Reflect Hepatitis B Virus in the Liver and Predict Treatment Response
    • DOI 10.1016/j.cgh.2007.09.005, PII S1542356507008919
    • H.L. Chan, V.W. Wong, and A.M. Tse Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response Clin Gastroenterol Hepatol 5 2007 1462 1468 (Pubitemid 350181604)
    • (2007) Clinical Gastroenterology and Hepatology , vol.5 , Issue.12 , pp. 1462-1468
    • Chan, H.L.1    Wong, V.W.2    Tse, A.M.3    Tse, C.4    Chim, A.M.5    Chan, H.6    Wong, G.L.7    Sung, J.J.8
  • 7
    • 31344476583 scopus 로고    scopus 로고
    • Integration of hepatitis B virus DNA into chromosonal DNA during acute hepatitis B
    • G.C. Kimbi, A. Kramvis, and M.C. Kew Integration of hepatitis B virus DNA into chromosomal DNA during acute hepatitis B World J Gastroenterol 11 2005 6416 6421 (Pubitemid 43136875)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.41 , pp. 6416-6421
    • Kimbi, G.C.1    Kramvis, A.2    Kew, M.C.3
  • 9
    • 84889816791 scopus 로고    scopus 로고
    • 3rd ed. Blackwell Publishing Massachusetts, USA
    • H.C. Thomas, and S.M. Lemon Viral hepatitis 3rd ed. 2005 Blackwell Publishing Massachusetts, USA
    • (2005) Viral Hepatitis
    • Thomas, H.C.1    Lemon, S.M.2
  • 10
    • 77949655619 scopus 로고    scopus 로고
    • Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia
    • T. Nguyen, A.J. Thompson, and S. Bowden Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia J Hepatol 52 2010 508 513
    • (2010) J Hepatol , vol.52 , pp. 508-513
    • Nguyen, T.1    Thompson, A.J.2    Bowden, S.3
  • 11
    • 77949656255 scopus 로고    scopus 로고
    • Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective
    • J. Jaroszewicz, B. Calle Serrano, and K. Wursthorn Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective J Hepatol 52 2010 514 522
    • (2010) J Hepatol , vol.52 , pp. 514-522
    • Jaroszewicz, J.1    Calle Serrano, B.2    Wursthorn, K.3
  • 12
    • 77952716572 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
    • A.J. Thompson, T. Nguyen, and D. Iser Serum hepatitis B surface antigen and hepatitis B e antigen titers: disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers Hepatology 51 2010 1933 1944
    • (2010) Hepatology , vol.51 , pp. 1933-1944
    • Thompson, A.J.1    Nguyen, T.2    Iser, D.3
  • 13
    • 77956598865 scopus 로고    scopus 로고
    • Relationship between serum hepatitis B virus DNA and surface antigen with covalently closed circular DNA in HBeAg-negative patients
    • L.Y. Lin, V.W. Wong, and H.J. Zhou Relationship between serum hepatitis B virus DNA and surface antigen with covalently closed circular DNA in HBeAg-negative patients J Med Virol 82 2010 1494 1500
    • (2010) J Med Virol , vol.82 , pp. 1494-1500
    • Lin, L.Y.1    Wong, V.W.2    Zhou, H.J.3
  • 14
    • 34548475512 scopus 로고    scopus 로고
    • Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients
    • DOI 10.1053/j.gastro.2007.06.057, PII S0016508507012899
    • T. Volz, M. Lutgehetmann, and P. Wachtler Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients Gastroenterology 133 2007 843 852 (Pubitemid 47374140)
    • (2007) Gastroenterology , vol.133 , Issue.3 , pp. 843-852
    • Volz, T.1    Lutgehetmann, M.2    Wachtler, P.3    Jacob, A.4    Quaas, A.5    Murray, J.M.6    Dandri, M.7    Petersen, J.8
  • 15
    • 47149111970 scopus 로고    scopus 로고
    • The antiviral drug selected hepatitis B virus rtA181T/sW172*mutant has a dominant negative secretion defect and alters the typical profile of viral rebound
    • DOI 10.1002/hep.22295
    • N. Warner, and S. Locarnini The antiviral drug selected hepatitis B virus rtA181T/sW172 mutant has a dominant negative secretion defect and alters the typical profile of viral rebound Hepatology 48 2008 88 98 (Pubitemid 351975534)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 88-98
    • Warner, N.1    Locarnini, S.2
  • 16
    • 67149133745 scopus 로고    scopus 로고
    • Can antiviral therapy for chronic hepatitis B enhance the progression to hepatocellular carcinoma?
    • N. Warner, and S. Locarnini Can antiviral therapy for chronic hepatitis B enhance the progression to hepatocellular carcinoma? Antivir Ther 14 2009 139 142
    • (2009) Antivir Ther , vol.14 , pp. 139-142
    • Warner, N.1    Locarnini, S.2
  • 17
    • 79957510053 scopus 로고    scopus 로고
    • Multicenter evaluation of the Elecsys HBsAg II Quant Assay
    • F. Bonino, F. Moriconi, and S. Bowden Multicenter evaluation of the Elecsys HBsAg II Quant Assay Hepatol Int 5 2011 80
    • (2011) Hepatol Int , vol.5 , pp. 80
    • Bonino, F.1    Moriconi, F.2    Bowden, S.3
  • 18
    • 80054773670 scopus 로고    scopus 로고
    • A comparison of two assays for quantification of hepatitis B surface antigen in serum of patients with chronic hepatitis B
    • Abstract 750
    • Sonneveld MJ, Rijckborst V, Boucher CAB, et al. A comparison of two assays for quantification of hepatitis B surface antigen in serum of patients with chronic hepatitis B. J Hepatol 2011;54:Abstract 750.
    • (2011) J Hepatol , vol.54
    • Sonneveld, M.J.1    Rijckborst, V.2    Cab, B.3
  • 19
    • 79952623084 scopus 로고    scopus 로고
    • Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum
    • K. Wursthorn, J. Jaroszewicz, and B.J. Zacher Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum J Clin Virol 50 2011 292 296
    • (2011) J Clin Virol , vol.50 , pp. 292-296
    • Wursthorn, K.1    Jaroszewicz, J.2    Zacher, B.J.3
  • 20
    • 68549130600 scopus 로고    scopus 로고
    • A review of the natural history of chronic hepatitis B in the era of transient elastography
    • H.L. Chan, G.L. Wong, and V.W. Wong A review of the natural history of chronic hepatitis B in the era of transient elastography Antivir Ther 14 2009 489 499
    • (2009) Antivir Ther , vol.14 , pp. 489-499
    • Chan, H.L.1    Wong, G.L.2    Wong, V.W.3
  • 22
    • 77957938721 scopus 로고    scopus 로고
    • A longitudinal study on the natural history of serum HBsAg changes in chronic hepatitis B
    • H.L. Chan, V.W. Wong, G.L. Wong, C.H. Tse, H.Y. Chan, and J.J. Sung A longitudinal study on the natural history of serum HBsAg changes in chronic hepatitis B Hepatology 52 2010 1232 1241
    • (2010) Hepatology , vol.52 , pp. 1232-1241
    • Chan, H.L.1    Wong, V.W.2    Wong, G.L.3    Tse, C.H.4    Chan, H.Y.5    Sung, J.J.6
  • 23
    • 80054728814 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen level is associated with liver fibrosis in patients with HBeAg-positive chronic hepatitis B
    • Abstract 362
    • Cheng PN, Tsai HW, Chang TT. Serum hepatitis B surface antigen level is associated with liver fibrosis in patients with HBeAg-positive chronic hepatitis B. J Hepatol 2011;54:Abstract 362.
    • (2011) J Hepatol , vol.54
    • Cheng, P.N.1    Tsai, H.W.2    Chang, T.T.3
  • 24
    • 58849110389 scopus 로고    scopus 로고
    • Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B
    • G.L. Wong, V.W. Wong, and P.C. Choi Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B Clin Gastroenterol Hepatol 7 2009 227 233
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 227-233
    • Wong, G.L.1    Wong, V.W.2    Choi, P.C.3
  • 26
    • 33646369150 scopus 로고    scopus 로고
    • Hepatitis B e antigen-negative chronic hepatitis B: Natural history and treatment
    • DOI 10.1055/s-2006-939751
    • S. Hadziyannis, and G.V. Papatheodoridis Hepatitis B e antigen-negative chronic hepatitis: natural history and treatment Semin Liver Dis 26 2006 130 141 (Pubitemid 43668255)
    • (2006) Seminars in Liver Disease , vol.26 , Issue.2 , pp. 130-141
    • Hadziyannis, S.J.1    Papatheodoridis, G.V.2
  • 28
    • 0036168816 scopus 로고    scopus 로고
    • Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: A long term cohort study
    • DOI 10.1016/S0168-8278(01)00266-5, PII S0168827801002665
    • M.R. Brunetto, F. Oiveri, and B. Coco Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon and untreated patients: a long term cohort study J Hepatol 36 2002 263 270 (Pubitemid 34146434)
    • (2002) Journal of Hepatology , vol.36 , Issue.2 , pp. 263-270
    • Brunetto, M.R.1    Oliveri, F.2    Coco, B.3    Leandro, G.4    Colombatto, P.5    Gorin, J.M.6    Bonino, F.7
  • 29
    • 0036916045 scopus 로고    scopus 로고
    • Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients
    • DOI 10.1046/j.1365-2893.2002.00352.x
    • J.J. Sung, H.L. Chan, and M.L. Wong Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients J Viral Hepat 9 2002 229 234 (Pubitemid 36005522)
    • (2002) Journal of Viral Hepatitis , vol.9 , Issue.3 , pp. 229-234
    • Sung, J.J.-Y.1    Chan, H.L.-Y.2    Wong, M.L.3    Tse, C.-H.4    Yuen, S.C.-H.5    Tam, J.S.-L.6    Leung, N.W.-Y.7
  • 32
    • 56149086622 scopus 로고    scopus 로고
    • Is there a meaninful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B infection?
    • G.V. Papatheodoridis, E.K. Manesis, and S. Manalakopoulos Is there a meaninful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B infection? Hepatology 48 2008 1451 1459
    • (2008) Hepatology , vol.48 , pp. 1451-1459
    • Papatheodoridis, G.V.1    Manesis, E.K.2    Manalakopoulos, S.3
  • 33
    • 66149175804 scopus 로고    scopus 로고
    • The natural history of chronic hepatitis B virus infection
    • B.J. McMahon The natural history of chronic hepatitis B virus infection Hepatology 49 2009 S45 S55
    • (2009) Hepatology , vol.49
    • McMahon, B.J.1
  • 34
    • 0035010523 scopus 로고    scopus 로고
    • Management of hepatitis B: 2000 - Summary of a workshop
    • A.S. Lok, E.J. Heathcote, and J.H. Hoofnagle Management of hepatitis B: 2000 - summary of a workshop Gastroenterology 120 2001 1828 1853 (Pubitemid 32523500)
    • (2001) Gastroenterology , vol.120 , Issue.7 , pp. 1828-1853
    • Lok, A.S.1    Heathcote, E.J.2    Hoofnagle, J.H.3
  • 35
    • 58149296156 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of chronic hepatitis B
    • European Association for the Study of the Liver
    • EASL clinical practice guidelines: management of chronic hepatitis B. European Association for the Study of the Liver. J Hepatol 2009;50:227-242.
    • (2009) J Hepatol , vol.50 , pp. 227-242
  • 36
    • 0036896285 scopus 로고    scopus 로고
    • Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection
    • DOI 10.1053/jhep.2002.36949
    • C.J. Chu, M. Hussain, and A.S.F. Lik Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection Hepatology 36 2002 1408 1415 (Pubitemid 35407438)
    • (2002) Hepatology , vol.36 , Issue.6 , pp. 1408-1415
    • Chu, C.-J.1    Hussain, M.2    Lok, A.S.F.3
  • 38
    • 36349010112 scopus 로고    scopus 로고
    • Hepatitis B virus DNA prediction rules for Hepatitis B e antigen-negative chronic hepatitis B
    • J.J. Feld, M. Ayers, and D. El-Ashry Hepatitis B virus DNA prediction rules for Hepatitis B e antigen-negative chronic hepatitis B Hepatology 46 2007 1070 1507
    • (2007) Hepatology , vol.46 , pp. 1070-1507
    • Feld, J.J.1    Ayers, M.2    El-Ashry, D.3
  • 39
    • 79960113229 scopus 로고    scopus 로고
    • Viral determinants of hepatitis B surface antigen seroclearance in hepatitis B e antigen-negative chronic hepatitis B patients
    • H.L. Chan, G.L. Wong, C.H. Tse, H.Y. Chan, and V.W. Wong Viral determinants of hepatitis B surface antigen seroclearance in hepatitis B e antigen-negative chronic hepatitis B patients J Infect Dis 204 2011 408 414
    • (2011) J Infect Dis , vol.204 , pp. 408-414
    • Chan, H.L.1    Wong, G.L.2    Tse, C.H.3    Chan, H.Y.4    Wong, V.W.5
  • 40
    • 84984584244 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen concentration correlates with HBV DNA level in patients with chronic hepatitis B
    • T.H. Su, C.S. Hsu, and C.L. Chen Serum hepatitis B surface antigen concentration correlates with HBV DNA level in patients with chronic hepatitis B Antivir Ther 15 2010 1133 1139
    • (2010) Antivir Ther , vol.15 , pp. 1133-1139
    • Su, T.H.1    Hsu, C.S.2    Chen, C.L.3
  • 41
    • 84984552614 scopus 로고    scopus 로고
    • Serum Hepatitis B surface antigen levels predict surface antigen loss in hepatitis B e antigen seroconverters
    • [Epub ahead of print]
    • Tseng TC, Liu CJ, Su TH, et al. Serum Hepatitis B surface antigen levels predict surface antigen loss in hepatitis B e antigen seroconverters. Gastroenterology, 2011[Epub ahead of print].
    • (2011) Gastroenterology
    • Tseng, T.C.1    Liu, C.J.2    Su, T.H.3
  • 42
    • 77955494346 scopus 로고    scopus 로고
    • Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers
    • M.R. Brunetto, F. Oliveri, and P. Colombatto Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers Gastroenterology 139 2010 483 490
    • (2010) Gastroenterology , vol.139 , pp. 483-490
    • Brunetto, M.R.1    Oliveri, F.2    Colombatto, P.3
  • 43
    • 79957478090 scopus 로고    scopus 로고
    • Quantitative HBsAg: A new specific marker for the diagnosis of HBsAg inactive carriage
    • M. Martinot-Peignoux, O. Lada, and A.C. Cardoso Quantitative HBsAg: A new specific marker for the diagnosis of HBsAg inactive carriage Hepatology 52 2010 992A
    • (2010) Hepatology , vol.52
    • Martinot-Peignoux, M.1    Lada, O.2    Cardoso, A.C.3
  • 44
    • 80054743542 scopus 로고    scopus 로고
    • Characterization of the inactive HBsAg carrier state with 3 year follow-up
    • Abstract 398
    • Yakut M, Bektas M, Seven G, et al. Characterization of the inactive HBsAg carrier state with 3 year follow-up. J Hepatol 2011;54:Abstract 398.
    • (2011) J Hepatol , vol.54
    • Yakut, M.1    Bektas, M.2    Seven, G.3
  • 45
    • 80054721615 scopus 로고    scopus 로고
    • Distribution patterns of serum hepatitis B surface antigen levels over the natural course of chronic hepatitis B: The role of age and immune phase
    • Abstract 373
    • Jang JW, Yoo SH, Ho BS, et al. Distribution patterns of serum hepatitis B surface antigen levels over the natural course of chronic hepatitis B: the role of age and immune phase. J Hepatol 2011;54:Abstract 373.
    • (2011) J Hepatol , vol.54
    • Jang, J.W.1    Yoo, S.H.2    Ho, B.S.3
  • 47
    • 77952725714 scopus 로고    scopus 로고
    • Durability of Peginterferon alfa-2a treatment at 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B
    • V.W. Wong, G.L. Wong, and K.K. Yan Durability of Peginterferon alfa-2a treatment at 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B Hepatology 51 2010 1945 1953
    • (2010) Hepatology , vol.51 , pp. 1945-1953
    • Wong, V.W.1    Wong, G.L.2    Yan, K.K.3
  • 48
    • 0028346964 scopus 로고
    • Measurement of HBsAg to monitor hepatitis B viral replication in patients on α-interferon therapy
    • H.L.A. Janssen, C.J. Kerhof-Los, R.A. Heijtink, and S.W. Schalm Measurement of HBsAg to monitor hepatitis B viral replication in patients on α-interferon therapy Antivir Res 23 1994 251 257 (Pubitemid 24122302)
    • (1994) Antiviral Research , vol.23 , Issue.3-4 , pp. 251-257
    • Janssen, H.L.A.1    Kerhof-Los, C.J.2    Heijtink, R.A.3    Schalm, S.W.4
  • 49
    • 78449281983 scopus 로고    scopus 로고
    • Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B
    • H.L. Chan, V.W. Wong, and A.M. Chim Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B Aliment Pharmacol Ther 32 2010 1323 1325
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1323-1325
    • Chan, H.L.1    Wong, V.W.2    Chim, A.M.3
  • 50
    • 69449102880 scopus 로고    scopus 로고
    • Low pretreatment serum HBsAg level and viral mutations as predictors of response to Peginterferon alfa-2b therapy in chronic hepatitis B
    • P. Tangkijvanich, P. Komolmit, and V. Mahachai Low pretreatment serum HBsAg level and viral mutations as predictors of response to Peginterferon alfa-2b therapy in chronic hepatitis B J Clin Virol 46 2009 117 123
    • (2009) J Clin Virol , vol.46 , pp. 117-123
    • Tangkijvanich, P.1    Komolmit, P.2    Mahachai, V.3
  • 51
    • 70449495525 scopus 로고    scopus 로고
    • On treatment monitoring of HBsAg levels to predict response to peginterferon alfa-2a in patients with HBeAg-positive chronic hepatitis B
    • G. Lau, P. Marcellin, and M. Brunetto On treatment monitoring of HBsAg levels to predict response to peginterferon alfa-2a in patients with HBeAg-positive chronic hepatitis B J Hepatol 50 2009 S333
    • (2009) J Hepatol , vol.50 , pp. 333
    • Lau, G.1    Marcellin, P.2    Brunetto, M.3
  • 52
    • 80054730877 scopus 로고    scopus 로고
    • NEPTUNE study: On-treatment HBsAg level analysis confirms prediction of response observed in phase 3 study of peginterferon alfa-2a in HBeAg-positive patients
    • Abstract 69
    • Gane E, Jia J, Han K, et al. NEPTUNE study: on-treatment HBsAg level analysis confirms prediction of response observed in phase 3 study of peginterferon alfa-2a in HBeAg-positive patients. J Hepatol 2011;54:Abstract 69.
    • (2011) J Hepatol , vol.54
    • Gane, E.1    Jia, J.2    Han, K.3
  • 53
    • 77957958049 scopus 로고    scopus 로고
    • Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline
    • M.J. Sonneveld, V. Rijckborst, C.A. Boucher, B.E. Hansen, and H.L. Janssen Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline Hepatology 52 2010 1251 1257
    • (2010) Hepatology , vol.52 , pp. 1251-1257
    • Sonneveld, M.J.1    Rijckborst, V.2    Boucher, C.A.3    Hansen, B.E.4    Janssen, H.L.5
  • 54
    • 79952206073 scopus 로고    scopus 로고
    • Further analysis is required to identify an early stopping rule for peginterferon therapy that is valid for all HBeAg-positive patients
    • T. Piratvisuth, and P. Marcellin Further analysis is required to identify an early stopping rule for peginterferon therapy that is valid for all HBeAg-positive patients Hepatology 53 2011 1054 1055
    • (2011) Hepatology , vol.53 , pp. 1054-1055
    • Piratvisuth, T.1    Marcellin, P.2
  • 55
    • 65449117946 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen levels: A guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • M.R. Brunetto, F. Moriconi, and F. Bonino Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B Hepatology 49 2009 1141 1150
    • (2009) Hepatology , vol.49 , pp. 1141-1150
    • Brunetto, M.R.1    Moriconi, F.2    Bonino, F.3
  • 56
    • 71849095145 scopus 로고    scopus 로고
    • Kinetic of HBsAg decline in patients with HBeAg-negative chronic hepatitis B treated with peginterferon alfa-2a according to genotype and its association with sustained HBsAg clearance 4 years post treatment
    • [Abstract]
    • M.R. Brunetto, F. Bonino, and P. Marcellin Kinetic of HBsAg decline in patients with HBeAg-negative chronic hepatitis B treated with peginterferon alfa-2a according to genotype and its association with sustained HBsAg clearance 4 years post treatment Hepatology 48 4 2008 965A [Abstract]
    • (2008) Hepatology , vol.48 , Issue.4
    • Brunetto, M.R.1    Bonino, F.2    Marcellin, P.3
  • 57
    • 71849100822 scopus 로고    scopus 로고
    • Kinetics of HBsAg decline during and following treatment of CHB: Early and rapid HBsAg decline during peginterferon-2a in predictive of HBsAg clearance
    • [Abstract]
    • M.R. Brunetto, D. Cavallone, and F. Moriconi Kinetics of HBsAg decline during and following treatment of CHB: early and rapid HBsAg decline during peginterferon-2a in predictive of HBsAg clearance Hepatology 48 4 2008 717A [Abstract]
    • (2008) Hepatology , vol.48 , Issue.4
    • Brunetto, M.R.1    Cavallone, D.2    Moriconi, F.3
  • 59
    • 79959578514 scopus 로고    scopus 로고
    • Baseline HBsAg level and on-treatment HBsAg and HBV DNA decline predict sustained virological response in HBeAg-negative chronic hepatitis B patients treated with peginterferon alfa-2a (Pegasys) and Adefovir (Hepsera); An interim analysis
    • Abstract 491
    • Takkenberg B, Zaaijer HL, De Niet A, et al. Baseline HBsAg level and on-treatment HBsAg and HBV DNA decline predict sustained virological response in HBeAg-negative chronic hepatitis B patients treated with peginterferon alfa-2a (Pegasys) and Adefovir (Hepsera); an interim analysis. Hepatology 2009;50:Abstract 491.
    • (2009) Hepatology , vol.50
    • Takkenberg, B.1    Zaaijer, H.L.2    De Niet, A.3
  • 60
    • 77955703978 scopus 로고    scopus 로고
    • Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels
    • V. Rijckborst, B.E. Hansen, and Y. Cakaloglu Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels Hepatology 52 2010 454 461
    • (2010) Hepatology , vol.52 , pp. 454-461
    • Rijckborst, V.1    Hansen, B.E.2    Cakaloglu, Y.3
  • 61
    • 65449123444 scopus 로고    scopus 로고
    • Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
    • R. Moucari, V. Mackiewicz, and O. Lada Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients Hepatology 49 2009 1151 1157
    • (2009) Hepatology , vol.49 , pp. 1151-1157
    • Moucari, R.1    MacKiewicz, V.2    Lada, O.3
  • 62
    • 77955383602 scopus 로고    scopus 로고
    • A randomized trial of peginterferon alpha-2a with or without ribavirin for HBeAg-negative chronic hepatitis B
    • V. Rijckborst, M.J. Ter Borg, and Y. Cakaloglu A randomized trial of peginterferon alpha-2a with or without ribavirin for HBeAg-negative chronic hepatitis B Am J Gastroenterol 105 2010 1762 1769
    • (2010) Am J Gastroenterol , vol.105 , pp. 1762-1769
    • Rijckborst, V.1    Ter Borg, M.J.2    Cakaloglu, Y.3
  • 63
    • 66449121130 scopus 로고    scopus 로고
    • Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a
    • [e1-4]
    • Marcellin P, Bonino F, Lau GK, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology 2009;136:2169-79 [e1-4].
    • (2009) Gastroenterology , vol.136 , pp. 2169-2179
    • Marcellin, P.1    Bonino, F.2    Lau, G.K.3
  • 65
    • 79957533576 scopus 로고    scopus 로고
    • On-treatment decline in serum HBsAg levels predicts sustained immune control 1 year post-treatment, subsequent HBsAg clearance in HBeAg-negative hepatitis B virus-infected patients treated with peginterferon alfa-2a
    • P. Marcellin, T. Piratvisuth, and M. Brunetto On-treatment decline in serum HBsAg levels predicts sustained immune control 1 year post-treatment, subsequent HBsAg clearance in HBeAg-negative hepatitis B virus-infected patients treated with peginterferon alfa-2a Hepatol Int 4 2010 151
    • (2010) Hepatol Int , vol.4 , pp. 151
    • Marcellin, P.1    Piratvisuth, T.2    Brunetto, M.3
  • 66
    • 79957499282 scopus 로고    scopus 로고
    • Early on-treatment HBsAg and HBV DNA levels identify HBeAg-negative patients not responding to 48 or 96 weeks of peginterferon alfa-2a therapy
    • Abstract 479
    • Rijckborst V, Hansen B, Ferenci P, et al. Early on-treatment HBsAg and HBV DNA levels identify HBeAg-negative patients not responding to 48 or 96 weeks of peginterferon alfa-2a therapy. Hepatology 2010;52:Abstract 479.
    • (2010) Hepatology , vol.52
    • Rijckborst, V.1    Hansen, B.2    Ferenci, P.3
  • 67
    • 73449089431 scopus 로고    scopus 로고
    • Influence of genotype on hepatitis B surface antigen kinetics in hepatitis B e antigen-negative patients treated with pegylated interferon-alpha2a
    • R. Moucari, M. Martinot-Peignoux, and V. Mackiewicz Influence of genotype on hepatitis B surface antigen kinetics in hepatitis B e antigen-negative patients treated with pegylated interferon-alpha2a Antivir Ther 14 2009 1183 1188
    • (2009) Antivir Ther , vol.14 , pp. 1183-1188
    • Moucari, R.1    Martinot-Peignoux, M.2    MacKiewicz, V.3
  • 68
    • 65449117946 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen levels: A guide to sutained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
    • M.R. Brunetto, F. Moriconi, and F. Bononi Hepatitis B virus surface antigen levels: a guide to sutained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B Hepatology 49 2009 1141 1150
    • (2009) Hepatology , vol.49 , pp. 1141-1150
    • Brunetto, M.R.1    Moriconi, F.2    Bononi, F.3
  • 70
    • 33847410055 scopus 로고    scopus 로고
    • Prediction of treatment-related HBsAg loss in HBeAg-negative chronic hepatitis B: A clue from serum HBsAg levels
    • E.K. Manesis, E.S. Hadziyannis, O.S. Angelopoulou, and S.J. Hadziyannis Prediction of treatment-related HBsAg loss in HBeAg-negative chronic hepatitis B: a clue from serum HBsAg levels Antivir Ther 12 2007 73 82 (Pubitemid 46340428)
    • (2007) Antiviral Therapy , vol.12 , Issue.1 , pp. 73-82
    • Manesis, E.K.1    Hadziyannis, E.S.2    Angelopoulou, O.P.3    Hadziyannis, S.J.4
  • 72
    • 68049090944 scopus 로고    scopus 로고
    • Clearance of serum HBsAg and anti-HBs seroconversion following antiviral therapy for chronic hepatitis B
    • O. Borgniet, P. Parvaz, and C. Bouix Clearance of serum HBsAg and anti-HBs seroconversion following antiviral therapy for chronic hepatitis B J Med Virol 81 2009 1336 1342
    • (2009) J Med Virol , vol.81 , pp. 1336-1342
    • Borgniet, O.1    Parvaz, P.2    Bouix, C.3
  • 73
    • 77956592924 scopus 로고    scopus 로고
    • Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients
    • K. Wursthorn, M. Jung, and A. Riva Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients Hepatology 52 2010 1611 1620
    • (2010) Hepatology , vol.52 , pp. 1611-1620
    • Wursthorn, K.1    Jung, M.2    Riva, A.3
  • 74
    • 77950594817 scopus 로고    scopus 로고
    • On-treatment serum HBsAg level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients
    • W. Cai, Q. Xie, and B. An On-treatment serum HBsAg level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients J Clin Virol 48 2010 22 26
    • (2010) J Clin Virol , vol.48 , pp. 22-26
    • Cai, W.1    Xie, Q.2    An, B.3
  • 75
    • 79951669706 scopus 로고    scopus 로고
    • Kinetics of hepatitis B surface antigen differ between treatment with peginterferon and entecavir
    • J.G. Reijnders, V. Rijckborst, and M.J. Sonneveld Kinetics of hepatitis B surface antigen differ between treatment with peginterferon and entecavir J Hepatol 54 2011 449 454
    • (2011) J Hepatol , vol.54 , pp. 449-454
    • Reijnders, J.G.1    Rijckborst, V.2    Sonneveld, M.J.3
  • 76
    • 80053918022 scopus 로고    scopus 로고
    • Prediction of HBsAg loss using HBsAg decline after long-term virological response to nucleos(t)ide analogue therapy for chronic hepatitis B
    • Abstract 381
    • Zoutendijk R, Hansen BE, Van Vuuren AJ, Boucher CA, Janssen HL. Prediction of HBsAg loss using HBsAg decline after long-term virological response to nucleos(t)ide analogue therapy for chronic hepatitis B. Hepatology 2010;52:Abstract 381.
    • (2010) Hepatology , vol.52
    • Zoutendijk, R.1    Hansen, B.E.2    Van Vuuren, A.J.3    Boucher, C.A.4    Janssen, H.L.5
  • 77
    • 80053917374 scopus 로고    scopus 로고
    • Long-term monitoring of HBsAg kinetics and prediction of HBsAg clearance in patients with chronic hepatitis B treated with nucleoside/nucleotide analogues
    • Abstract 374
    • Chevaliez S, Hezode C, Grare M, Pawlotsky JM. Long-term monitoring of HBsAg kinetics and prediction of HBsAg clearance in patients with chronic hepatitis B treated with nucleoside/nucleotide analogues. Hepatology 2010;52:Abstract 374.
    • (2010) Hepatology , vol.52
    • Chevaliez, S.1    Hezode, C.2    Grare, M.3    Pawlotsky, J.M.4
  • 78
    • 80054749158 scopus 로고    scopus 로고
    • Prediction of HBsAg loss by quantitative HBsAg kinetics during long-term treatment with nucleos(t)ide analogues
    • Abstract 395
    • Jaroszewicz J, Ho H, Deterding K, et al. Prediction of HBsAg loss by quantitative HBsAg kinetics during long-term treatment with nucleos(t)ide analogues. Hepatology 2010;52:Abstract 395.
    • (2010) Hepatology , vol.52
    • Jaroszewicz, J.1    Ho, H.2    Deterding, K.3
  • 79
    • 78650477355 scopus 로고    scopus 로고
    • Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B
    • E.J. Heathcote, P. Marcellin, and M. Buti Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B Gastroenterology 140 2011 132 143
    • (2011) Gastroenterology , vol.140 , pp. 132-143
    • Heathcote, E.J.1    Marcellin, P.2    Buti, M.3
  • 80
    • 80053928899 scopus 로고    scopus 로고
    • HBsAg kinetics in patients with chronic hepatitis B (CHB) treated with tenofovir disoproxil fumarate (TDF) for up to 4 years
    • Abstract 740
    • Marcellin P, Heathcote EJ, Buti M, et al. HBsAg kinetics in patients with chronic hepatitis B (CHB) treated with tenofovir disoproxil fumarate (TDF) for up to 4 years. J Hepatol 2011;54:Abstract 740.
    • (2011) J Hepatol , vol.54
    • Marcellin, P.1    Heathcote, E.J.2    Buti, M.3
  • 81
    • 80054762059 scopus 로고    scopus 로고
    • Serum HBsAg quantification can predict sustained response to lamivudine in patients with negative HBeAg: A long-term post-treatment study
    • Abstract PP05-102
    • Chan HL, Wong GL, Chim AM, Chan HY, Chu SH, Wong VW. Serum HBsAg quantification can predict sustained response to lamivudine in patients with negative HBeAg: a long-term post-treatment study. Hepatol Int 2011;5:Abstract PP05-102.
    • (2011) Hepatol Int , vol.5
    • Chan, H.L.1    Wong, G.L.2    Chim, A.M.3    Chan, H.Y.4    Chu, S.H.5    Wong, V.W.6
  • 82
    • 80054773506 scopus 로고    scopus 로고
    • Study of influence factors on HBV relapse after NAS withdrawal in the CHB patients who met NAS cessation criteria
    • Abstract 722
    • Jiang NJ, Liang XY, Su HM, et al. Study of influence factors on HBV relapse after NAS withdrawal in the CHB patients who met NAS cessation criteria. J Hepatol 2011;54:Abstract 722.
    • (2011) J Hepatol , vol.54
    • Jiang, N.J.1    Liang, X.Y.2    Su, H.M.3
  • 83
    • 79957508583 scopus 로고    scopus 로고
    • Significance of serum HBsAg levels for the definition of the inactive hepatitis B carrier
    • Abstract 483
    • Manesis EK, Papatheodoridis GV, Hadziyannis E. Significance of serum HBsAg levels for the definition of the inactive hepatitis B carrier. Hepatology 2010;52:Abstract 483.
    • (2010) Hepatology , vol.52
    • Manesis, E.K.1    Papatheodoridis, G.V.2    Hadziyannis, E.3
  • 84
    • 80054726996 scopus 로고    scopus 로고
    • Mutations in the HBs-antigen influence the results of HBsAg quantification assays
    • Abstract 394
    • Verheyen J, Neumann-Fraune M, Berg T, Kaiser R, Obermeier M. Mutations in the HBs-antigen influence the results of HBsAg quantification assays. J Hepatol 2011;54:Abstract 394.
    • (2011) J Hepatol , vol.54
    • Verheyen, J.1    Neumann-Fraune, M.2    Berg, T.3    Kaiser, R.4    Obermeier, M.5
  • 85
    • 80054754292 scopus 로고    scopus 로고
    • Mutation RTA181T/SW172 is associated with lower HBsAg levels than other mutations in HBV polymerase codon 181 an overlapping surface codon 172 - Implications for vaccination?
    • Abstract 706
    • Bruce M, Horner M, Shang D, et al. Mutation RTA181T/SW172 is associated with lower HBsAg levels than other mutations in HBV polymerase codon 181 an overlapping surface codon 172 - implications for vaccination? J Hepatol 2011:54:Abstract 706.
    • (2011) J Hepatol , vol.54
    • Bruce, M.1    Horner, M.2    Shang, D.3


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