Organophosphate-induced brain damage: Mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies

NeuroToxicology

Volumn 33, Issue 3, 2012, Pages 391-400

  Chen, Yun ^a  

^a BrightstarTech Inc   (United States)

Author keywords

Acetylcholinesterase; Cholinergic neuronal excitotoxicity; Nerve agents; Neurological impairments; Neuroprotective strategies; Neuropsychiatric disorders; Organophosphates; Secondary neuronal damage

Indexed keywords

ACETYLCHOLINE; ALPHA TOCOPHEROL; ANTIOXIDANT; CHOLINERGIC RECEPTOR BLOCKING AGENT; DIURETIC AGENT; MANNITOL; MEMANTINE; MITOQ; MUSCARINIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; ORGANOPHOSPHATE; STEROID; UNCLASSIFIED DRUG;

AMNESIA; APOPTOSIS; BLOOD BRAIN BARRIER; BLURRED VISION; BRAIN CANCER; BRAIN DAMAGE; BRAIN EDEMA; CELL THERAPY; COGNITIVE DEFECT; DEMENTIA; DIFFUSION WEIGHTED IMAGING; DIZZINESS; DROWSINESS; EMOTIONAL DISORDER; HUMAN; INFLAMMATION; INTOXICATION; MEMORY DISORDER; MENTAL DISEASE; NAUSEA; NERVE DEGENERATION; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROPSYCHOLOGY; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; POSTTRAUMATIC STRESS DISORDER; PRACTICE GUIDELINE; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; PSYCHOSOMATIC DISORDER; REVIEW; TRAUMATIC BRAIN INJURY; XEROSTOMIA;

ACETYLCHOLINESTERASE; ANIMALS; ANTIDOTES; BRAIN; CHOLINESTERASE INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; PHOSPHORIC ACID ESTERS; TREATMENT OUTCOME;

EID: 84859908304     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.03.011     Document Type: Review

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