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Volumn 31, Issue 5, 2010, Pages 493-501

Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans

Author keywords

Brain; Central nervous system; Chemical warfare agents; Cognitive functioning; Cyclosarin; Gulf War veterans; Magnetic resonance imaging; Morphometric analysis; Sarin

Indexed keywords

CYCLOSARIN; SARIN;

EID: 77956224922     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2010.05.006     Document Type: Article
Times cited : (116)

References (44)
  • 2
    • 0033933649 scopus 로고    scopus 로고
    • Voxel-based morphometry-the methods
    • Ashburner J., Friston K.J. Voxel-based morphometry-the methods. NeuroImage 2000, 11:805-821.
    • (2000) NeuroImage , vol.11 , pp. 805-821
    • Ashburner, J.1    Friston, K.J.2
  • 6
    • 23044507108 scopus 로고    scopus 로고
    • Mortality in US army Gulf War veterans exposed to 1991 Khamisiyah chemical munitions destruction
    • Bullman T.A., Mahan C.M., Kang H.K., Page W.F. Mortality in US army Gulf War veterans exposed to 1991 Khamisiyah chemical munitions destruction. Am J Public Health 2005, 95:1382-1388.
    • (2005) Am J Public Health , vol.95 , pp. 1382-1388
    • Bullman, T.A.1    Mahan, C.M.2    Kang, H.K.3    Page, W.F.4
  • 8
    • 77956227997 scopus 로고    scopus 로고
    • Directorate for Deployment Health Support of the Special Assistant to the Under Secretary of Defense (Personnel and Readiness) for Gulf War Illness Medical Readiness and Military Deployments. Potential exposure to sarin from the demolitions at Khamisiyah, Iraq on March 10, 1991
    • Directorate for Deployment Health Support of the Special Assistant to the Under Secretary of Defense (Personnel and Readiness) for Gulf War Illness Medical Readiness and Military Deployments. Potential exposure to sarin from the demolitions at Khamisiyah, Iraq on March 10, 1991. Available at: 1997. http://www.gulflink.osd.mil/.
    • (1997)
  • 9
    • 77956231226 scopus 로고    scopus 로고
    • Directorate for Deployment Health Support of the Special Assistant to the Under Secretary of Defense (Personnel and Readiness) for Gulf War Illness Medical Readiness and Military Deployments. US demolition operations at the Khamisiyah ammunition point (case narrative)
    • Directorate for Deployment Health Support of the Special Assistant to the Under Secretary of Defense (Personnel and Readiness) for Gulf War Illness Medical Readiness and Military Deployments. US demolition operations at the Khamisiyah ammunition point (case narrative). Available at: 2002. http://www.gulflink.osd.mil/khamishaii.
    • (2002)
  • 11
    • 0032538047 scopus 로고    scopus 로고
    • Chronic multisymptom illness affecting Air Force veterans of the Gulf War
    • Fukuda K., Nisenbaum R., Stewart G., Thompson W.W., Robin L., Washko R.M., et al. Chronic multisymptom illness affecting Air Force veterans of the Gulf War. JAMA 1998, 280:981-988.
    • (1998) JAMA , vol.280 , pp. 981-988
    • Fukuda, K.1    Nisenbaum, R.2    Stewart, G.3    Thompson, W.W.4    Robin, L.5    Washko, R.M.6
  • 12
    • 0036830012 scopus 로고    scopus 로고
    • Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
    • Gilbertson M.W., Shenton M.E., Ciszewski A., Kasai K., Lasko N.B., Orr S.P., et al. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 2002, 5:1242-1247.
    • (2002) Nat Neurosci , vol.5 , pp. 1242-1247
    • Gilbertson, M.W.1    Shenton, M.E.2    Ciszewski, A.3    Kasai, K.4    Lasko, N.B.5    Orr, S.P.6
  • 13
    • 74249112977 scopus 로고    scopus 로고
    • Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman
    • Gullapalli R.P., Aracava Y., Zhuo J., Helal Neto E., Wang J., Makris G., et al. Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman. Neurotoxicology 2010, 31:67-76.
    • (2010) Neurotoxicology , vol.31 , pp. 67-76
    • Gullapalli, R.P.1    Aracava, Y.2    Zhuo, J.3    Helal Neto, E.4    Wang, J.5    Makris, G.6
  • 14
    • 0030560641 scopus 로고    scopus 로고
    • Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder
    • Gurvits T.V., Shenton M.E., Hokama H., Ohta H., Lasko N.B., Gilbertson M.W., et al. Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol Psychiatry 1996, 40:1091-1099.
    • (1996) Biol Psychiatry , vol.40 , pp. 1091-1099
    • Gurvits, T.V.1    Shenton, M.E.2    Hokama, H.3    Ohta, H.4    Lasko, N.B.5    Gilbertson, M.W.6
  • 15
    • 0031030843 scopus 로고    scopus 로고
    • Self-reported exposure to neurotoxic chemical combinations in the Gulf War
    • Haley R.W., Kurt T.L. Self-reported exposure to neurotoxic chemical combinations in the Gulf War. JAMA 1997, 277:231-237.
    • (1997) JAMA , vol.277 , pp. 231-237
    • Haley, R.W.1    Kurt, T.L.2
  • 16
    • 0031021513 scopus 로고    scopus 로고
    • Is there a Gulf War syndrome?
    • Haley R.W., Kurt T.L., Hom J. Is there a Gulf War syndrome?. JAMA 1997, 277:215-222.
    • (1997) JAMA , vol.277 , pp. 215-222
    • Haley, R.W.1    Kurt, T.L.2    Hom, J.3
  • 17
    • 34447344036 scopus 로고    scopus 로고
    • Quantitative magnetic resonance brain imaging in US army veterans of the 1991 Gulf War potentially exposed to sarin and cyclosarin
    • Heaton K.J., Palumbo C.L., Proctor S.P., Killiany R.J., Yurgelun-Todd D.A., et al. Quantitative magnetic resonance brain imaging in US army veterans of the 1991 Gulf War potentially exposed to sarin and cyclosarin. Neurotoxicology 2007, 28:761-769.
    • (2007) Neurotoxicology , vol.28 , pp. 761-769
    • Heaton, K.J.1    Palumbo, C.L.2    Proctor, S.P.3    Killiany, R.J.4    Yurgelun-Todd, D.A.5
  • 18
    • 0036707981 scopus 로고    scopus 로고
    • Comparison of automated and manual MRI of hippocampus in normal aging and dementia
    • Hsu Y.Y., Schuff N., Du A.T., Mark K., Zhu X., Weiner M.W. Comparison of automated and manual MRI of hippocampus in normal aging and dementia. J Mag Res Imaging 2002, 16:305-310.
    • (2002) J Mag Res Imaging , vol.16 , pp. 305-310
    • Hsu, Y.Y.1    Schuff, N.2    Du, A.T.3    Mark, K.4    Zhu, X.5    Weiner, M.W.6
  • 19
    • 0020577156 scopus 로고
    • The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig
    • Inns R.H., Leadbeater L. The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig. J Pharm Pharmacol 1983, 35:427-433.
    • (1983) J Pharm Pharmacol , vol.35 , pp. 427-433
    • Inns, R.H.1    Leadbeater, L.2
  • 20
    • 0003498689 scopus 로고
    • Neurobehavioral Systems, Inc., Cambridge, MA
    • Letz R.L. NES2 user's manual 1991, Neurobehavioral Systems, Inc., Cambridge, MA.
    • (1991) NES2 user's manual
    • Letz, R.L.1
  • 22
    • 74249083670 scopus 로고    scopus 로고
    • An acute exposure to a sub-lethal dose of soman tirggers anxiety-related behavior in guinea pigs: interactions with acute restraint
    • Mamczarz J., Pereira E.F., Aracava Y., Adler M., Albuquerque E.X. An acute exposure to a sub-lethal dose of soman tirggers anxiety-related behavior in guinea pigs: interactions with acute restraint. Neurotoxicology 2010, 31:77-84.
    • (2010) Neurotoxicology , vol.31 , pp. 77-84
    • Mamczarz, J.1    Pereira, E.F.2    Aracava, Y.3    Adler, M.4    Albuquerque, E.X.5
  • 23
    • 77956231537 scopus 로고
    • Toxicological basis for controlling emission of GB into the environment. Aberdeen Proving Grounds, MD: Edgewood Arsenal: US Army Medical Research Laboratories
    • McNamara B, Leitnaker F. Toxicological basis for controlling emission of GB into the environment. Aberdeen Proving Grounds, MD: Edgewood Arsenal: US Army Medical Research Laboratories, 1971.
    • (1971)
    • McNamara, B.1    Leitnaker, F.2
  • 24
    • 25444489291 scopus 로고    scopus 로고
    • Effects of sarin on the nervous system of subway workers seven years after the Tokyo subway sarin attack
    • Miyaki K., Nishiwaki Y., Maekawa K., Ogawa Y., Asukai N., Yoshimura K., et al. Effects of sarin on the nervous system of subway workers seven years after the Tokyo subway sarin attack. J Occup Health 2005, 47:299-304.
    • (2005) J Occup Health , vol.47 , pp. 299-304
    • Miyaki, K.1    Nishiwaki, Y.2    Maekawa, K.3    Ogawa, Y.4    Asukai, N.5    Yoshimura, K.6
  • 25
    • 0035203343 scopus 로고    scopus 로고
    • Effects of sarin on the nervous system in rescue team staff members and police officers 3 years after the Tokyo subway sarin attack
    • Nishiwaki Y., Maekawa K., Ogawa Y., Asukai N., Minami M., Omae K. Effects of sarin on the nervous system in rescue team staff members and police officers 3 years after the Tokyo subway sarin attack. Envrion Health Perspect 2001, 109:1169-1173.
    • (2001) Envrion Health Perspect , vol.109 , pp. 1169-1173
    • Nishiwaki, Y.1    Maekawa, K.2    Ogawa, Y.3    Asukai, N.4    Minami, M.5    Omae, K.6
  • 26
    • 0012199840 scopus 로고    scopus 로고
    • Persian Gulf War Illness Task Force, Central Intelligence Agency, Washington, DC
    • Persian Gulf War Illness Task Force Khamisiyah: a historical perspective on related intelligence 1997, Central Intelligence Agency, Washington, DC.
    • (1997) Khamisiyah: a historical perspective on related intelligence
  • 27
    • 33751551136 scopus 로고    scopus 로고
    • Effects of chemical warfare agent exposure on central nervous system functioning in US army veterans of the 1991 Gulf War
    • Proctor S.P., Heaton K.J., Heeren T., White R.F. Effects of chemical warfare agent exposure on central nervous system functioning in US army veterans of the 1991 Gulf War. Neurotoxicology 2006, 27:931-939.
    • (2006) Neurotoxicology , vol.27 , pp. 931-939
    • Proctor, S.P.1    Heaton, K.J.2    Heeren, T.3    White, R.F.4
  • 28
    • 0032413334 scopus 로고    scopus 로고
    • Health status of Persian Gulf War veterans: self-reported symptoms, environmental exposures and the effect of stress
    • Proctor S.P., Heeren T., White R.F., Wolfe J., Borgos M.S., Davis J.D., et al. Health status of Persian Gulf War veterans: self-reported symptoms, environmental exposures and the effect of stress. Int J Epidemiol 1998, 27:1000-1010.
    • (1998) Int J Epidemiol , vol.27 , pp. 1000-1010
    • Proctor, S.P.1    Heeren, T.2    White, R.F.3    Wolfe, J.4    Borgos, M.S.5    Davis, J.D.6
  • 30
    • 0043076349 scopus 로고    scopus 로고
    • Chemical warfare and the Gulf War: a review of the impact on Gulf veterans' health
    • Riddle J.R., Brown M., Smith T., Ritchie E.C., Brix K.A., Romano J. Chemical warfare and the Gulf War: a review of the impact on Gulf veterans' health. Mil Med 2003, 168:606-613.
    • (2003) Mil Med , vol.168 , pp. 606-613
    • Riddle, J.R.1    Brown, M.2    Smith, T.3    Ritchie, E.C.4    Brix, K.A.5    Romano, J.6
  • 31
    • 0042510806 scopus 로고    scopus 로고
    • Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited
    • Smith T.C., Gray G.C., Weir J.C., Heller J.M., Ryan M.A. Gulf War veterans and Iraqi nerve agents at Khamisiyah: postwar hospitalization data revisited. Am J Epidemiol 2003, 158:457-467.
    • (2003) Am J Epidemiol , vol.158 , pp. 457-467
    • Smith, T.C.1    Gray, G.C.2    Weir, J.C.3    Heller, J.M.4    Ryan, M.A.5
  • 33
    • 0034669707 scopus 로고    scopus 로고
    • Prevalence and patterns of GulfWar illness in Kansas veterans: association of symptoms with characteristics of person, place, and time of military service
    • Steele L. Prevalence and patterns of GulfWar illness in Kansas veterans: association of symptoms with characteristics of person, place, and time of military service. Am J Epidemiol 2000, 152:992-1002.
    • (2000) Am J Epidemiol , vol.152 , pp. 992-1002
    • Steele, L.1
  • 36
  • 37
    • 0025144266 scopus 로고
    • Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse
    • Veronesi B., Jones K., Pope C. Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse. Toxicol Appl Pharmacol 1990, 104:440-456.
    • (1990) Toxicol Appl Pharmacol , vol.104 , pp. 440-456
    • Veronesi, B.1    Jones, K.2    Pope, C.3
  • 40
    • 0034935010 scopus 로고    scopus 로고
    • Neuropsychological function in Gulf War veterans: relationships to selfreported toxicant exposures
    • White R.F., Proctor S.P., Heeren T., Wolfe J., Krengel M., Vasterling J., et al. Neuropsychological function in Gulf War veterans: relationships to selfreported toxicant exposures. Am J Ind Med 2001, 40:42-54.
    • (2001) Am J Ind Med , vol.40 , pp. 42-54
    • White, R.F.1    Proctor, S.P.2    Heeren, T.3    Wolfe, J.4    Krengel, M.5    Vasterling, J.6
  • 42
    • 0036119565 scopus 로고    scopus 로고
    • Risk factors for multisymptom illness in US Army veterans of the Gulf War
    • Wolfe J., Proctor S., Erickson D., Hu H. Risk factors for multisymptom illness in US Army veterans of the Gulf War. J Occup Environ Med 2002, 44:271-281.
    • (2002) J Occup Environ Med , vol.44 , pp. 271-281
    • Wolfe, J.1    Proctor, S.2    Erickson, D.3    Hu, H.4
  • 43
    • 33846828686 scopus 로고    scopus 로고
    • Human brain structural change related to acute single exposure to sarin
    • Yamasue H., Abe O., Kasai K., Suga M., Iwanami A., Yamada H., et al. Human brain structural change related to acute single exposure to sarin. Ann Neurol 2007, 61:37-46.
    • (2007) Ann Neurol , vol.61 , pp. 37-46
    • Yamasue, H.1    Abe, O.2    Kasai, K.3    Suga, M.4    Iwanami, A.5    Yamada, H.6
  • 44
    • 0031830234 scopus 로고    scopus 로고
    • Chronic neurobehavioral effects of Tokyo subway sarin poisoning in relation to posttraumatic stress disorder
    • Yokoyama K., Araki S., Murata K., Nishikitani M., Okumura T., Ishimatsu S., et al. Chronic neurobehavioral effects of Tokyo subway sarin poisoning in relation to posttraumatic stress disorder. Arch Environ Health 1998, 53:249-256.
    • (1998) Arch Environ Health , vol.53 , pp. 249-256
    • Yokoyama, K.1    Araki, S.2    Murata, K.3    Nishikitani, M.4    Okumura, T.5    Ishimatsu, S.6


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