-
1
-
-
60549114749
-
Synthesis and evaluation of novel bis-pyridinium oximes as reactivators of DFP-inhibited acetylcholinesterase
-
Acharya, J., Gupta, A. K., Dubey, D. K., and Raza, S. K. (2009). Synthesis and evaluation of novel bis-pyridinium oximes as reactivators of DFP-inhibited acetylcholinesterase. Eur. J. Med. Chem. 44, 1335-1340.
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 1335-1340
-
-
Acharya, J.1
Gupta, A.K.2
Dubey, D.K.3
Raza, S.K.4
-
2
-
-
35349018354
-
Unequal efficacy of pyridinium oximes in acute organophosphate poisoning
-
Antonijevic, B., and Stojiljkovic, M. P. (2007). Unequal efficacy of pyridinium oximes in acute organophosphate poisoning. Clin. Med. Res. 5, 71-82.
-
(2007)
Clin. Med. Res.
, vol.5
, pp. 71-82
-
-
Antonijevic, B.1
Stojiljkovic, M.P.2
-
3
-
-
1242306547
-
Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity
-
Auta, J., Costa, E., Davis, J., and Guidotti, A. (2004). Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity. Neuropharmacology 46, 397-403.
-
(2004)
Neuropharmacology
, vol.46
, pp. 397-403
-
-
Auta, J.1
Costa, E.2
Davis, J.3
Guidotti, A.4
-
4
-
-
10044275708
-
Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment
-
Bajgar, J. (2004). Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv. Clin. Chem. 38, 151-216.
-
(2004)
Adv. Clin. Chem.
, vol.38
, pp. 151-216
-
-
Bajgar, J.1
-
5
-
-
77955075256
-
Mechanism of seizures induced by di-isopropyl flurophosphate (DFP)
-
Bouzarth, W. F., and Himwich, H. E. (1952). Mechanism of seizures induced by di-isopropyl flurophosphate (DFP). Am. J. Psychiatry 108, 847-855.
-
(1952)
Am. J. Psychiatry
, vol.108
, pp. 847-855
-
-
Bouzarth, W.F.1
Himwich, H.E.2
-
6
-
-
0013208747
-
Progress on the road to new nerve agent treatments
-
Broomfield, C. A., and Kirby, S. D. (2001). Progress on the road to new nerve agent treatments. J. Appl. Toxicol. 21(Suppl. 1), S43-S46.
-
(2001)
J. Appl. Toxicol.
, vol.21
, Issue.SUPPL. 1
-
-
Broomfield, C.A.1
Kirby, S.D.2
-
7
-
-
23044525066
-
Science and prohibited weapons
-
Coupland, R., and Leins, K.-R. (2005). Science and prohibited weapons. Science 308, 1841.
-
(2005)
Science
, vol.308
, pp. 1841
-
-
Coupland, R.1
Leins, K.-R.2
-
8
-
-
77955078575
-
-
Paper presented at the Scientific Conference on Chemical and Biological Defense Research, Hunt Valley, MD, A976944
-
Crawford, S. M., Compton, J. R., Tetz, L. M., Ratcliffe, R. H., Steele, K. E., Gordon, R. K., and Nambiar, M. P. (2004). Development of a rat diisopropylfluorophosphate-induced seizure/status epilepticus model for screening of neuroprotectants following exposure to chemical warfare agents. Paper presented at the Scientific Conference on Chemical and Biological Defense Research, Hunt Valley, MD, A976944.
-
(2004)
Development of a rat diisopropylfluorophosphate-induced seizure/status epilepticus model for screening of neuroprotectants following exposure to chemical warfare agents
-
-
Crawford, S.M.1
Compton, J.R.2
Tetz, L.M.3
Ratcliffe, R.H.4
Steele, K.E.5
Gordon, R.K.6
Nambiar, M.P.7
-
9
-
-
14544282458
-
Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy
-
DeLorenzo, R. J., Sun, D. A., and Deshpande, L. S. (2005). Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy. Pharmacol. Ther. 105, 229-266.
-
(2005)
Pharmacol. Ther.
, vol.105
, pp. 229-266
-
-
DeLorenzo, R.J.1
Sun, D.A.2
Deshpande, L.S.3
-
10
-
-
46149087237
-
Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury
-
Deshpande, L. S., Sun, D. A., Sombati, S., Baranova, A., Wilson, M. S., Attkisson, E. A., Hamm, R. J., and DeLorenzo, R. J. (2008). Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Neurosci. Lett. 441, 115-119.
-
(2008)
Neurosci. Lett.
, vol.441
, pp. 115-119
-
-
Deshpande, L.S.1
Sun, D.A.2
Sombati, S.3
Baranova, A.4
Wilson, M.S.5
Attkisson, E.A.6
Hamm, R.J.7
DeLorenzo, R.J.8
-
11
-
-
2342530435
-
Chemical warfare in the Iran-Iraq conflict
-
Dingeman, A., and Jupa, R. (1987). Chemical warfare in the Iran-Iraq conflict. Strategy Tactics Mag 113, 51-52.
-
(1987)
Strategy Tactics Mag
, vol.113
, pp. 51-52
-
-
Dingeman, A.1
Jupa, R.2
-
12
-
-
2442702807
-
The role of oximes in the management of organophosphorus pesticide poisoning
-
Eyer, P. (2003). The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol. Rev. 22, 165-190.
-
(2003)
Toxicol. Rev.
, vol.22
, pp. 165-190
-
-
Eyer, P.1
-
13
-
-
77955083581
-
Neuroprotection for nerve agent-induced brain damage by blocking delayed calcium overload: a review
-
(online)
-
Filbert, M., Levine, E., and Ballough, G. (2005). Neuroprotection for nerve agent-induced brain damage by blocking delayed calcium overload: a review. J. Med. Chem. Biol. Radiol. Def. 3 (online).
-
(2005)
J. Med. Chem. Biol. Radiol. Def.
, vol.3
-
-
Filbert, M.1
Levine, E.2
Ballough, G.3
-
14
-
-
41949132813
-
Acetylcholinesterase inhibitors and Gulf War illnesses
-
Golomb, B. A. (2008). Acetylcholinesterase inhibitors and Gulf War illnesses. Proc. Natl Acad. Sci. U.S.A. 105, 4295-4300.
-
(2008)
Proc. Natl Acad. Sci. U. S. A.
, vol.105
, pp. 4295-4300
-
-
Golomb, B.A.1
-
16
-
-
58349102708
-
Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage
-
Kadriu, B., Guidotti, A., Costa, E., and Auta, J. (2009). Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage. Toxicology 256, 164-174.
-
(2009)
Toxicology
, vol.256
, pp. 164-174
-
-
Kadriu, B.1
Guidotti, A.2
Costa, E.3
Auta, J.4
-
17
-
-
0024787541
-
Organophosphorus insecticide poisoning
-
Karalliedde, L., and Senanayake, N. (1989). Organophosphorus insecticide poisoning. Br. J. Anaesth. 63, 736-750.
-
(1989)
Br. J. Anaesth.
, vol.63
, pp. 736-750
-
-
Karalliedde, L.1
Senanayake, N.2
-
18
-
-
0020634082
-
Histological and histochemical changes in the central nervous system of the rat poisoned by an irreversible anticholinesterase organophosphorus compound
-
Lemercier, G., Carpentier, P., Sentenac-Roumanou, H., and Morelis, P. (1983). Histological and histochemical changes in the central nervous system of the rat poisoned by an irreversible anticholinesterase organophosphorus compound. Acta Neuropathol. 61, 123-129.
-
(1983)
Acta Neuropathol
, vol.61
, pp. 123-129
-
-
Lemercier, G.1
Carpentier, P.2
Sentenac-Roumanou, H.3
Morelis, P.4
-
19
-
-
0031754195
-
Review of health consequences from high-, intermediateand low-level exposure to organophosphorus nerve agents
-
Mark, A. B., and Kelley, A. B. (1998). Review of health consequences from high-, intermediateand low-level exposure to organophosphorus nerve agents. J. Appl. Toxicol. 18, 393-408.
-
(1998)
J. Appl. Toxicol.
, vol.18
, pp. 393-408
-
-
Mark, A.B.1
Kelley, A.B.2
-
20
-
-
0027263472
-
Pharmacological modulation of soman-induced seizures
-
McDonough, J. H., Jr, and Shih, T. M. (1993). Pharmacological modulation of soman-induced seizures. Neurosci. Biobehav. Rev. 17, 203-215.
-
(1993)
Neurosci. Biobehav. Rev.
, vol.17
, pp. 203-215
-
-
McDonough J.H., Jr.1
Shih, T.M.2
-
21
-
-
0030726679
-
Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology
-
McDonough, J. H., Jr, and Shih, T. M. (1997). Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology. Neurosci. Biobehav. Rev. 21, 559-579.
-
(1997)
Neurosci. Biobehav. Rev.
, vol.21
, pp. 559-579
-
-
McDonough J.H., Jr.1
Shih, T.M.2
-
22
-
-
2342663624
-
The birth of nerve agent warfare: lessons from Syed Abbas Foroutan
-
Newmark, J. (2004). The birth of nerve agent warfare: lessons from Syed Abbas Foroutan. Neurology 62, 1590-1596.
-
(2004)
Neurology
, vol.62
, pp. 1590-1596
-
-
Newmark, J.1
-
23
-
-
67649996733
-
Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis
-
Nagarkatti, N., Deshpande, L. S., and DeLorenzo, R. J. (2009). Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis. Expert Rev. Neurother. 9, 813-824.
-
(2009)
Expert Rev. Neurother.
, vol.9
, pp. 813-824
-
-
Nagarkatti, N.1
Deshpande, L.S.2
DeLorenzo, R.J.3
-
24
-
-
50649110261
-
Reactivation of DFP-and paraoxon-inhibited acetylcholinesterases by pyridinium oximes
-
Oh, K. A., Park, N. J., Park, N. S., Kuca, K., Jun, D., and Jung, Y. S. (2008). Reactivation of DFP-and paraoxon-inhibited acetylcholinesterases by pyridinium oximes. Chem. Biol. Interact. 175(1-3), 365-367.
-
(2008)
Chem. Biol. Interact.
, vol.175
, Issue.1-3
, pp. 365-367
-
-
Oh, K.A.1
Park, N.J.2
Park, N.S.3
Kuca, K.4
Jun, D.5
Jung, Y.S.6
-
25
-
-
52949084679
-
The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice
-
Pibiri, F., Kozikowski, A. P., Pinna, G., Auta, J., Kadriu, B., Costa, E., and Guidotti, A. (2008). The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. Proc. Natl Acad. Sci. U.S.A. 105, 14169-14174.
-
(2008)
Proc. Natl Acad. Sci. U.S.A.
, vol.105
, pp. 14169-14174
-
-
Pibiri, F.1
Kozikowski, A.P.2
Pinna, G.3
Auta, J.4
Kadriu, B.5
Costa, E.6
Guidotti, A.7
-
26
-
-
0015309163
-
Modification of seizure activity by electrical stimulation: II. Motor seizure
-
Racine, R. J. (1972). Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32, 281-294.
-
(1972)
Electroencephalogr. Clin. Neurophysiol.
, vol.32
, pp. 281-294
-
-
Racine, R.J.1
-
27
-
-
10644229215
-
Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy
-
Raza, M., Blair, R. E., Sombati, S., Carter, D. S., Deshpande, L. S., and DeLorenzo, R. J. (2004). Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proc. Natl Acad. Sci. U.S.A. 101, 17522-17527.
-
(2004)
Proc. Natl Acad. Sci. U.S.A.
, vol.101
, pp. 17522-17527
-
-
Raza, M.1
Blair, R.E.2
Sombati, S.3
Carter, D.S.4
Deshpande, L.S.5
DeLorenzo, R.J.6
-
28
-
-
0031738370
-
Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits
-
Rice, A. C., Floyd, C. L., Lyeth, B. G., Hamm, R. J., and DeLorenzo, R. J. (1998). Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia 39, 1148-1157.
-
(1998)
Epilepsia
, vol.39
, pp. 1148-1157
-
-
Rice, A.C.1
Floyd, C.L.2
Lyeth, B.G.3
Hamm, R.J.4
DeLorenzo, R.J.5
-
29
-
-
77955073982
-
Status epilepticus in the developing brain: Long-term effects seen in humans
-
s12
-
Rod, C. S. (2009). Status epilepticus in the developing brain: Long-term effects seen in humans. Epilepsia 50(s12), 32-33.
-
(2009)
Epilepsia
, vol.50
, pp. 32-33
-
-
Rod, C.S.1
-
30
-
-
0037446246
-
Control of nerve agent-induced seizures is critical for neuroprotection and survival
-
Shih, T. M., Duniho, S. M., and McDonough, J. H. (2003). Control of nerve agent-induced seizures is critical for neuroprotection and survival. Toxicol. Appl. Pharmacol. 188, 69-80.
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.188
, pp. 69-80
-
-
Shih, T.M.1
Duniho, S.M.2
McDonough, J.H.3
-
31
-
-
41549084205
-
Traumatic brain injury causes a long-lasting calcium-plateau of elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons surviving the brain injury
-
Sun, D. A., Deshpande, L. S., Sombati, S., Baranova, A., Wilson, M. S., Hamm, R. J., and DeLorenzo, R. J. (2008). Traumatic brain injury causes a long-lasting calcium-plateau of elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons surviving the brain injury. Eur. J. Neurosci. 27, 1659-1672.
-
(2008)
Eur. J. Neurosci.
, vol.27
, pp. 1659-1672
-
-
Sun, D.A.1
Deshpande, L.S.2
Sombati, S.3
Baranova, A.4
Wilson, M.S.5
Hamm, R.J.6
DeLorenzo, R.J.7
-
32
-
-
33746907449
-
Development of a rat pilocarpine model of seizure/status epilepticus that mimics chemical warfare nerve agent exposure
-
Tetz, L. M., Rezk, P. E., Ratcliffe, R. H., Gordon, R. K., Steele, K. E., and Nambiar, M. P. (2006). Development of a rat pilocarpine model of seizure/status epilepticus that mimics chemical warfare nerve agent exposure. Toxicol. Ind. Health 22, 255-266.
-
(2006)
Toxicol. Ind. Health
, vol.22
, pp. 255-266
-
-
Tetz, L.M.1
Rezk, P.E.2
Ratcliffe, R.H.3
Gordon, R.K.4
Steele, K.E.5
Nambiar, M.P.6
-
33
-
-
1242316228
-
Organophosphate-induced convulsions and prevention of neuropathological damages
-
Tuovinen, K. (2004). Organophosphate-induced convulsions and prevention of neuropathological damages. Toxicology 196, 31-39.
-
(2004)
Toxicology
, vol.196
, pp. 31-39
-
-
Tuovinen, K.1
-
34
-
-
0021020387
-
Cholinomimetics produce seizures and brain damage in rats
-
Turski, W. A., Czuczwar, S. J., Kleinrok, Z., and Turski, L. (1983). Cholinomimetics produce seizures and brain damage in rats. Experientia 39, 1408-1411.
-
(1983)
Experientia
, vol.39
, pp. 1408-1411
-
-
Turski, W.A.1
Czuczwar, S.J.2
Kleinrok, Z.3
Turski, L.4
-
35
-
-
77951205497
-
Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics
-
Wright, L. K., Liu, J., Nallapaneni, A., and Pope, C. N. (2009). Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics. Neurotoxicol. Teratol. 32, 329-335.
-
(2009)
Neurotoxicol. Teratol.
, vol.32
, pp. 329-335
-
-
Wright, L.K.1
Liu, J.2
Nallapaneni, A.3
Pope, C.N.4
-
36
-
-
0029952621
-
Clinical profiles of patients with sarin poisoning after the Tokyo subway attack
-
Yokoyama, K., Yamada, A., and Mimura, N. (1996). Clinical profiles of patients with sarin poisoning after the Tokyo subway attack. Am. J. Med. 100, 586.
-
(1996)
Am. J. Med.
, vol.100
, pp. 586
-
-
Yokoyama, K.1
Yamada, A.2
Mimura, N.3
|