Protective efficacy of mitochondrial targeted antioxidant MitoQ against dichlorvos induced oxidative stress and cell death in rat brain

Neuropharmacology

Volumn 61, Issue 8, 2011, Pages 1193-1201

  Wani, Willayat Yousuf ^a   Gudup, Satish ^b   Sunkaria, Aditya ^a   Bal, Amanjit ^a   Singh, Parvinder Pal ^b   Kandimalla, Ramesh J L ^a   Sharma, Deep Raj ^a   Gill, Kiran Dip ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Dichlorvos; MitoQ; Neurodegeneration; Organophosphate; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTIOXIDANT; CASPASE 3; CYTOCHROME C; DICHLORVOS; DNA; GLUTATHIONE; LIPID; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; MITOQ; PROTEIN; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN MITOCHONDRION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA FRAGMENTATION; DNA OXIDATION; DRUG EFFICACY; DRUG TARGETING; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MITOCHONDRION SWELLING; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN OXIDATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION;

ANIMALS; ANTIOXIDANTS; BRAIN; CASPASE 3; CELL DEATH; CHOLINESTERASE INHIBITORS; CYTOCHROMES C; DICHLORVOS; LIPID PEROXIDATION; MALE; MITOCHONDRIA; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDE DISMUTASE; UBIQUINONE;

EID: 80053602345     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.07.008     Document Type: Article

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