메뉴 건너뛰기




Volumn 21, Issue 4, 2012, Pages 459-472

Targeting Nonclassical Oncogenes for Therapy in T-ALL

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; ANTINEOPLASTIC AGENT; CAL 130; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UNCLASSIFIED DRUG;

EID: 84859807614     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.02.029     Document Type: Article
Times cited : (84)

References (61)
  • 2
    • 74049121331 scopus 로고    scopus 로고
    • Contribution of bone microenvironment to leukemogenesis and leukemia progression
    • Ayala F., Dewar R., Kieran M., Kalluri R. Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia 2009, 23:2233-2241.
    • (2009) Leukemia , vol.23 , pp. 2233-2241
    • Ayala, F.1    Dewar, R.2    Kieran, M.3    Kalluri, R.4
  • 3
    • 67349261310 scopus 로고    scopus 로고
    • Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism
    • Beesley A.H., Firth M.J., Ford J., Weller R.E., Freitas J.R., Perera K.U., Kees U.R. Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism. Br. J. Cancer 2009, 100:1926-1936.
    • (2009) Br. J. Cancer , vol.100 , pp. 1926-1936
    • Beesley, A.H.1    Firth, M.J.2    Ford, J.3    Weller, R.E.4    Freitas, J.R.5    Perera, K.U.6    Kees, U.R.7
  • 4
    • 0023864317 scopus 로고
    • Molecular mechanisms of a t(8;14)(q24;q11) translocation juxtaposing c-myc and TcR-alpha genes in a T-cell leukaemia: involvement of a V alpha internal heptamer
    • Bernard O., Larsen C.J., Hampe A., Mauchauffé M., Berger R., Mathieu-Mahul D. Molecular mechanisms of a t(8;14)(q24;q11) translocation juxtaposing c-myc and TcR-alpha genes in a T-cell leukaemia: involvement of a V alpha internal heptamer. Oncogene 1988, 2:195-200.
    • (1988) Oncogene , vol.2 , pp. 195-200
    • Bernard, O.1    Larsen, C.J.2    Hampe, A.3    Mauchauffé, M.4    Berger, R.5    Mathieu-Mahul, D.6
  • 5
    • 70350734809 scopus 로고    scopus 로고
    • The microenvironment in mature B-cell malignancies: a target for new treatment strategies
    • Burger J.A., Ghia P., Rosenwald A., Caligaris-Cappio F. The microenvironment in mature B-cell malignancies: a target for new treatment strategies. Blood 2009, 114:3367-3375.
    • (2009) Blood , vol.114 , pp. 3367-3375
    • Burger, J.A.1    Ghia, P.2    Rosenwald, A.3    Caligaris-Cappio, F.4
  • 6
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 11
    • 58149175555 scopus 로고    scopus 로고
    • The life of a cell: apoptosis regulation by the PI3K/PKB pathway
    • Duronio V. The life of a cell: apoptosis regulation by the PI3K/PKB pathway. Biochem. J. 2008, 415:333-344.
    • (2008) Biochem. J. , vol.415 , pp. 333-344
    • Duronio, V.1
  • 12
    • 28844472952 scopus 로고    scopus 로고
    • BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo
    • Erlacher M., Michalak E.M., Kelly P.N., Labi V., Niederegger H., Coultas L., Adams J.M., Strasser A., Villunger A. BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. Blood 2005, 106:4131-4138.
    • (2005) Blood , vol.106 , pp. 4131-4138
    • Erlacher, M.1    Michalak, E.M.2    Kelly, P.N.3    Labi, V.4    Niederegger, H.5    Coultas, L.6    Adams, J.M.7    Strasser, A.8    Villunger, A.9
  • 14
    • 0022972786 scopus 로고
    • A common mechanism of chromosomal translocation in T- and B-cell neoplasia
    • Finger L.R., Harvey R.C., Moore R.C., Showe L.C., Croce C.M. A common mechanism of chromosomal translocation in T- and B-cell neoplasia. Science 1986, 234:982-985.
    • (1986) Science , vol.234 , pp. 982-985
    • Finger, L.R.1    Harvey, R.C.2    Moore, R.C.3    Showe, L.C.4    Croce, C.M.5
  • 15
    • 70449471819 scopus 로고    scopus 로고
    • Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes
    • Finlay D.K., Sinclair L.V., Feijoo C., Waugh C.M., Hagenbeek T.J., Spits H., Cantrell D.A. Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes. J. Exp. Med. 2009, 206:2441-2454.
    • (2009) J. Exp. Med. , vol.206 , pp. 2441-2454
    • Finlay, D.K.1    Sinclair, L.V.2    Feijoo, C.3    Waugh, C.M.4    Hagenbeek, T.J.5    Spits, H.6    Cantrell, D.A.7
  • 20
    • 40749131244 scopus 로고    scopus 로고
    • T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus
    • Hagenbeek T.J., Spits H. T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus. Leukemia 2008, 22:608-619.
    • (2008) Leukemia , vol.22 , pp. 608-619
    • Hagenbeek, T.J.1    Spits, H.2
  • 22
    • 0029556979 scopus 로고
    • T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination
    • Hennet T., Hagen F.K., Tabak L.A., Marth J.D. T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA 1995, 92:12070-12074.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12070-12074
    • Hennet, T.1    Hagen, F.K.2    Tabak, L.A.3    Marth, J.D.4
  • 23
    • 33646370512 scopus 로고    scopus 로고
    • BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance
    • Hickey F.B., Cotter T.G. BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance. J. Biol. Chem. 2006, 281:2441-2450.
    • (2006) J. Biol. Chem. , vol.281 , pp. 2441-2450
    • Hickey, F.B.1    Cotter, T.G.2
  • 24
    • 2442681621 scopus 로고    scopus 로고
    • The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development
    • Hinton H.J., Alessi D.R., Cantrell D.A. The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development. Nat. Immunol. 2004, 5:539-545.
    • (2004) Nat. Immunol. , vol.5 , pp. 539-545
    • Hinton, H.J.1    Alessi, D.R.2    Cantrell, D.A.3
  • 25
    • 80053345977 scopus 로고    scopus 로고
    • The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia
    • Hoellenriegel J., Meadows S.A., Sivina M., Wierda W.G., Kantarjian H., Keating M.J., Giese N., O'Brien S., Yu A., Miller L.L., et al. The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia. Blood 2011, 118:3603-3612.
    • (2011) Blood , vol.118 , pp. 3603-3612
    • Hoellenriegel, J.1    Meadows, S.A.2    Sivina, M.3    Wierda, W.G.4    Kantarjian, H.5    Keating, M.J.6    Giese, N.7    O'Brien, S.8    Yu, A.9    Miller, L.L.10
  • 26
    • 65349155706 scopus 로고    scopus 로고
    • Induction of Akt activity by chemotherapy confers acquired resistance
    • Huang W.C., Hung M.C. Induction of Akt activity by chemotherapy confers acquired resistance. J. Formos. Med. Assoc. 2009, 108:180-194.
    • (2009) J. Formos. Med. Assoc. , vol.108 , pp. 180-194
    • Huang, W.C.1    Hung, M.C.2
  • 31
    • 31944448780 scopus 로고    scopus 로고
    • Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase
    • Kang S., Denley A., Vanhaesebroeck B., Vogt P.K. Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase. Proc. Natl. Acad. Sci. USA 2006, 103:1289-1294.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1289-1294
    • Kang, S.1    Denley, A.2    Vanhaesebroeck, B.3    Vogt, P.K.4
  • 33
    • 0035190026 scopus 로고    scopus 로고
    • Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer
    • Katso R., Okkenhaug K., Ahmadi K., White S., Timms J., Waterfield M.D. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 2001, 17:615-675.
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 615-675
    • Katso, R.1    Okkenhaug, K.2    Ahmadi, K.3    White, S.4    Timms, J.5    Waterfield, M.D.6
  • 34
    • 70349735988 scopus 로고    scopus 로고
    • Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches
    • Konopleva M., Tabe Y., Zeng Z., Andreeff M. Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches. Drug Resist. Updat. 2009, 12:103-113.
    • (2009) Drug Resist. Updat. , vol.12 , pp. 103-113
    • Konopleva, M.1    Tabe, Y.2    Zeng, Z.3    Andreeff, M.4
  • 35
    • 68749109333 scopus 로고    scopus 로고
    • The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group
    • Larson Gedman A., Chen Q., Kugel Desmoulin S., Ge Y., LaFiura K., Haska C.L., Cherian C., Devidas M., Linda S.B., Taub J.W., Matherly L.H. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia 2009, 23:1417-1425.
    • (2009) Leukemia , vol.23 , pp. 1417-1425
    • Larson Gedman, A.1    Chen, Q.2    Kugel Desmoulin, S.3    Ge, Y.4    LaFiura, K.5    Haska, C.L.6    Cherian, C.7    Devidas, M.8    Linda, S.B.9    Taub, J.W.10    Matherly, L.H.11
  • 37
    • 68649105674 scopus 로고    scopus 로고
    • Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing
    • Lo T.C., Barnhill L.M., Kim Y., Nakae E.A., Yu A.L., Diccianni M.B. Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing. Leuk. Res. 2009, 33:1562-1566.
    • (2009) Leuk. Res. , vol.33 , pp. 1562-1566
    • Lo, T.C.1    Barnhill, L.M.2    Kim, Y.3    Nakae, E.A.4    Yu, A.L.5    Diccianni, M.B.6
  • 39
    • 0038549067 scopus 로고    scopus 로고
    • PI3K in lymphocyte development, differentiation and activation
    • Okkenhaug K., Vanhaesebroeck B. PI3K in lymphocyte development, differentiation and activation. Nat. Rev. Immunol. 2003, 3:317-330.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 317-330
    • Okkenhaug, K.1    Vanhaesebroeck, B.2
  • 40
    • 43549123531 scopus 로고    scopus 로고
    • The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia
    • Palomero T., Dominguez M., Ferrando A.A. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia. Cell Cycle 2008, 7:965-970.
    • (2008) Cell Cycle , vol.7 , pp. 965-970
    • Palomero, T.1    Dominguez, M.2    Ferrando, A.A.3
  • 42
    • 0037369696 scopus 로고    scopus 로고
    • Essential role of phosphoinositide 3-kinase δ in neutrophil directional movement
    • Sadhu C., Masinovsky B., Dick K., Sowell C.G., Staunton D.E. Essential role of phosphoinositide 3-kinase δ in neutrophil directional movement. J. Immunol. 2003, 170:2647-2654.
    • (2003) J. Immunol. , vol.170 , pp. 2647-2654
    • Sadhu, C.1    Masinovsky, B.2    Dick, K.3    Sowell, C.G.4    Staunton, D.E.5
  • 43
    • 1642516133 scopus 로고    scopus 로고
    • Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination
    • Safran M., Kim W.Y., Kung A.L., Horner J.W., DePinho R.A., Kaelin W.G. Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination. Mol. Imaging 2003, 2:297-302.
    • (2003) Mol. Imaging , vol.2 , pp. 297-302
    • Safran, M.1    Kim, W.Y.2    Kung, A.L.3    Horner, J.W.4    DePinho, R.A.5    Kaelin, W.G.6
  • 44
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • Salmena L., Carracedo A., Pandolfi P.P. Tenets of PTEN tumor suppression. Cell 2008, 133:403-414.
    • (2008) Cell , vol.133 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 46
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle T., Hall M.N. TOR, a central controller of cell growth. Cell 2000, 103:253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 48
    • 77249100829 scopus 로고    scopus 로고
    • Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation
    • Sopasakis V.R., Liu P., Suzuki R., Kondo T., Winnay J., Tran T.T., Asano T., Smyth G., Sajan M.P., Farese R.V., et al. Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation. Cell Metab. 2010, 11:220-230.
    • (2010) Cell Metab. , vol.11 , pp. 220-230
    • Sopasakis, V.R.1    Liu, P.2    Suzuki, R.3    Kondo, T.4    Winnay, J.5    Tran, T.T.6    Asano, T.7    Smyth, G.8    Sajan, M.P.9    Farese, R.V.10
  • 51
    • 0142011466 scopus 로고    scopus 로고
    • PTEN: from pathology to biology
    • Sulis M.L., Parsons R. PTEN: from pathology to biology. Trends Cell Biol. 2003, 13:478-483.
    • (2003) Trends Cell Biol. , vol.13 , pp. 478-483
    • Sulis, M.L.1    Parsons, R.2
  • 54
    • 34547402441 scopus 로고    scopus 로고
    • T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses
    • Tarasenko T., Kole H.K., Chi A.W., Mentink-Kane M.M., Wynn T.A., Bolland S. T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses. Proc. Natl. Acad. Sci. USA 2007, 104:11382-11387.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 11382-11387
    • Tarasenko, T.1    Kole, H.K.2    Chi, A.W.3    Mentink-Kane, M.M.4    Wynn, T.A.5    Bolland, S.6
  • 56
    • 0037592259 scopus 로고    scopus 로고
    • Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis
    • Wang Z., Malone M.H., He H., McColl K.S., Distelhorst C.W. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J. Biol. Chem. 2003, 278:23861-23867.
    • (2003) J. Biol. Chem. , vol.278 , pp. 23861-23867
    • Wang, Z.1    Malone, M.H.2    He, H.3    McColl, K.S.4    Distelhorst, C.W.5
  • 57
    • 23844462453 scopus 로고    scopus 로고
    • Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase
    • Webb L.M., Vigorito E., Wymann M.P., Hirsch E., Turner M.J. Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J. Immunol. 2005, 175:2783-2787.
    • (2005) J. Immunol. , vol.175 , pp. 2783-2787
    • Webb, L.M.1    Vigorito, E.2    Wymann, M.P.3    Hirsch, E.4    Turner, M.J.5
  • 59
    • 51849111556 scopus 로고    scopus 로고
    • PI3K pathway alterations in cancer: variations on a theme
    • Yuan T.L., Cantley L.C. PI3K pathway alterations in cancer: variations on a theme. Oncogene 2008, 27:5497-5510.
    • (2008) Oncogene , vol.27 , pp. 5497-5510
    • Yuan, T.L.1    Cantley, L.C.2
  • 60
    • 51849128358 scopus 로고    scopus 로고
    • Class I PI3K in oncogenic cellular transformation
    • Zhao L., Vogt P.K. Class I PI3K in oncogenic cellular transformation. Oncogene 2008, 27:5486-5496.
    • (2008) Oncogene , vol.27 , pp. 5486-5496
    • Zhao, L.1    Vogt, P.K.2
  • 61
    • 48449091227 scopus 로고    scopus 로고
    • Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha
    • Zunder E.R., Knight Z.A., Houseman B.T., Apsel B., Shokat K.M. Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha. Cancer Cell 2008, 14:180-192.
    • (2008) Cancer Cell , vol.14 , pp. 180-192
    • Zunder, E.R.1    Knight, Z.A.2    Houseman, B.T.3    Apsel, B.4    Shokat, K.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.