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Volumn 24, Issue 1, 2010, Pages 239-242

Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 74249086850     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.209     Document Type: Letter
Times cited : (83)

References (8)
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    • PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability
    • Silva A, Yunes JA, Cardoso BA, Martins LR, Jotta PY, Abecasis M et al. PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability. J Clin Invest 2008; 118: 3762-3774.
    • (2008) J Clin Invest , vol.118 , pp. 3762-3774
    • Silva, A.1    Yunes, J.A.2    Cardoso, B.A.3    Martins, L.R.4    Jotta, P.Y.5    Abecasis, M.6
  • 2
    • 34250863886 scopus 로고    scopus 로고
    • Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
    • Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A et al. Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers. Nature 2007; 447: 966-971.
    • (2007) Nature , vol.447 , pp. 966-971
    • Maser, R.S.1    Choudhury, B.2    Campbell, P.J.3    Feng, B.4    Wong, K.K.5    Protopopov, A.6
  • 3
    • 34948908663 scopus 로고    scopus 로고
    • Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
    • Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med 2007; 13: 1203-1210.
    • (2007) Nat Med , vol.13 , pp. 1203-1210
    • Palomero, T.1    Sulis, M.L.2    Cortina, M.3    Real, P.J.4    Barnes, K.5    Ciofani, M.6
  • 4
    • 70149087158 scopus 로고    scopus 로고
    • High frequency of PTEN, PI3K and AKT abnormalities in T-cell acute lymphoblastic leukemia
    • Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y et al. High frequency of PTEN, PI3K and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood 2009; 114: 647-650.
    • (2009) Blood , vol.114 , pp. 647-650
    • Gutierrez, A.1    Sanda, T.2    Grebliunaite, R.3    Carracedo, A.4    Salmena, L.5    Ahn, Y.6
  • 5
    • 70349235938 scopus 로고    scopus 로고
    • High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-{beta} and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response
    • Remke M, Pfister S, Kox C, Toedt G, Becker N, Benner A et al. High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-{beta} and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response. Blood 2009; 114: 1053-1062.
    • (2009) Blood , vol.114 , pp. 1053-1062
    • Remke, M.1    Pfister, S.2    Kox, C.3    Toedt, G.4    Becker, N.5    Benner, A.6
  • 6
    • 68749109333 scopus 로고    scopus 로고
    • The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: A report from the Children's Oncology Group
    • Larson GA, Chen Q, Kugel DS, Ge Y, Lafiura K, Haska CL et al. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia 2009; 23: 1417-1425.
    • (2009) Leukemia , vol.23 , pp. 1417-1425
    • Larson, G.A.1    Chen, Q.2    Kugel, D.S.3    Ge, Y.4    Lafiura, K.5    Haska, C.L.6
  • 7
    • 71049164788 scopus 로고    scopus 로고
    • MRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death
    • Cortez MA, Scrideli CA, Yunes JA, Valera ET, Toledo S, Pavoni-Ferreira PCB et al. mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death. Pediatric Blood Câncer 2009; 53: 996-1004.
    • (2009) Pediatric Blood Câncer , vol.53 , pp. 996-1004
    • Cortez, M.A.1    Scrideli, C.A.2    Yunes, J.A.3    Valera, E.T.4    Toledo, S.5    Pavoni-Ferreira, P.C.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.