-
1
-
-
0035020950
-
Phosphoinositide 3-kinase signalling pathways
-
Cantrell DA. Phosphoinositide 3-kinase signalling pathways. J Cell Sci 2001; 114 (Part 8): 1439-1445.
-
(2001)
J Cell Sci
, vol.114
, Issue.PART 8
, pp. 1439-1445
-
-
Cantrell, D.A.1
-
2
-
-
0033136288
-
Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors
-
Pallard C, Stegmann AP, van Kleffens T, Smart F, Venkitaraman A, Spits H. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999; 10: 525-535.
-
(1999)
Immunity
, vol.10
, pp. 525-535
-
-
Pallard, C.1
Stegmann, A.P.2
van Kleffens, T.3
Smart, F.4
Venkitaraman, A.5
Spits, H.6
-
3
-
-
25444442035
-
Regulated costimulation in the thymus is critical for T cell development: Dysregulted CD28 costimulation can bypass the pre-TCR checkpoint
-
Williams JA, Hathcock, KS, Klug D, Harada. Y, Choudloury B, Allison JP et al. Regulated costimulation in the thymus is critical for T cell development: Dysregulted CD28 costimulation can bypass the pre-TCR checkpoint. J Immunol 2005; 175: 4199-4207.
-
(2005)
J Immunol
, vol.175
, pp. 4199-4207
-
-
Williams, J.A.1
Hathcock, K.S.2
Klug, D.3
Harada, Y.4
Choudloury, B.5
Allison, J.P.6
-
4
-
-
0034995242
-
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
-
Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, Kimura Y et al T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity 2001; 14: 523-534.
-
(2001)
Immunity
, vol.14
, pp. 523-534
-
-
Suzuki, A.1
Yamaguchi, M.T.2
Ohteki, T.3
Sasaki, T.4
Kaisho, T.5
Kimura, Y.6
-
5
-
-
1342292522
-
Phosphoinositide 3-kinase: Diverse roles in immune cell activation
-
Deane JA, Fruman DA. Phosphoinositide 3-kinase: Diverse roles in immune cell activation. Annu Rev Immunol 2004; 22: 563-598.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 563-598
-
-
Deane, J.A.1
Fruman, D.A.2
-
6
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha
-
Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB et al Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha. Curr Biol 1997; 7: 261-269.
-
(1997)
Curr Biol
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
-
7
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005; 307: 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
8
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 2002; 4: 648-657.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
9
-
-
4544331713
-
Activation of P13K is indispensable for interleukin 7-mediated viability, proliferation,. glucose use, and growth of T cell acute lymphoblastic leukemia cells
-
Barata JT, Silva A, Brandao JG, Nadler LM, Cardoso AA, Boussiotis VA. Activation of P13K is indispensable for interleukin 7-mediated viability, proliferation,. glucose use, and growth of T cell acute lymphoblastic leukemia cells. J Exp Med 2004; 200: 659-669.
-
(2004)
J Exp Med
, vol.200
, pp. 659-669
-
-
Barata, J.T.1
Silva, A.2
Brandao, J.G.3
Nadler, L.M.4
Cardoso, A.A.5
Boussiotis, V.A.6
-
10
-
-
0033517189
-
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999; 401: 82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
11
-
-
0032526586
-
The trophic action of IL-7 on pro-T cells: Inhibition of apoptosis of pro-T1, J2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways
-
Kim K, Lee CK, Sayers TJ, Muegge K, Durum SK. The trophic action of IL-7 on pro-T cells: Inhibition of apoptosis of pro-T1, J2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. J Immunol 1998; 160: 5735-5741.
-
(1998)
J Immunol
, vol.160
, pp. 5735-5741
-
-
Kim, K.1
Lee, C.K.2
Sayers, T.J.3
Muegge, K.4
Durum, S.K.5
-
12
-
-
0031815678
-
The role of interleukin-7 in early T-cell development
-
Offner F, Plum J. The role of interleukin-7 in early T-cell development. Leuk Lymphoma 1998; 30: 87-99.
-
(1998)
Leuk Lymphoma
, vol.30
, pp. 87-99
-
-
Offner, F.1
Plum, J.2
-
13
-
-
0035908029
-
Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2
-
Rodewald HR, Waskow C, Haller C. Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2. J Exp Med 2001; 193: 1431-1437.
-
(2001)
J Exp Med
, vol.193
, pp. 1431-1437
-
-
Rodewald, H.R.1
Waskow, C.2
Haller, C.3
-
14
-
-
24944444760
-
Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism
-
Ciofani M, Zuniga-Pflucker JC. Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. Nat Immunol 2005; 6: 881-888.
-
(2005)
Nat Immunol
, vol.6
, pp. 881-888
-
-
Ciofani, M.1
Zuniga-Pflucker, J.C.2
-
15
-
-
30444454357
-
Developmental and molecular characterization of emerging beta-and gammadelta-selected pre-T cells in the adult mouse thymus
-
Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV. Developmental and molecular characterization of emerging beta-and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity 2006; 24: 53-64.
-
(2006)
Immunity
, vol.24
, pp. 53-64
-
-
Taghon, T.1
Yui, M.A.2
Pant, R.3
Diamond, R.A.4
Rothenberg, E.V.5
-
16
-
-
0027168220
-
Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: A critical role for the beta chain in development
-
Mallick CA, Dudley EC, Viney JL, Owen MJ, Hayday AC. Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: A critical role for the beta chain in development. Cell 1993; 73: 513-519.
-
(1993)
Cell
, vol.73
, pp. 513-519
-
-
Mallick, C.A.1
Dudley, E.C.2
Viney, J.L.3
Owen, M.J.4
Hayday, A.C.5
-
17
-
-
0033119330
-
Pleiotropic changes controlled by the pre-T-cell receptor
-
von Boehmer H, Aifantis I, Feinberg J, Lechner O, Saint-Ruf C, Walter U et al. Pleiotropic changes controlled by the pre-T-cell receptor. Curr Opin Immunol 1999; 11: 135-142.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 135-142
-
-
von Boehmer, H.1
Aifantis, I.2
Feinberg, J.3
Lechner, O.4
Saint-Ruf, C.5
Walter, U.6
-
18
-
-
0037306064
-
An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors
-
Hayes SM, Shores EW, Love PE. An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors. Immunol Rev 2003; 191: 28-37.
-
(2003)
Immunol Rev
, vol.191
, pp. 28-37
-
-
Hayes, S.M.1
Shores, E.W.2
Love, P.E.3
-
19
-
-
34247627902
-
Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition
-
Mao C, Tili EG, Dose M, Haks MC, Bear SE, Maroulakou I et al. Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol 2007; 178: 5443-5453.
-
(2007)
J Immunol
, vol.178
, pp. 5443-5453
-
-
Mao, C.1
Tili, E.G.2
Dose, M.3
Haks, M.C.4
Bear, S.E.5
Maroulakou, I.6
-
20
-
-
0034305495
-
Control of pre-T cell proliferation and differentiation by the GTPase Rac-1
-
Gomez M, Tybulewicz V, Cantrell DA. Control of pre-T cell proliferation and differentiation by the GTPase Rac-1. Nat Immunol 2000; 1 348-352.
-
(2000)
Nat Immunol
, vol.1
, pp. 348-352
-
-
Gomez, M.1
Tybulewicz, V.2
Cantrell, D.A.3
-
21
-
-
0032445491
-
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
-
Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J Exp Med 1998; 188: 2301-2311.
-
(1998)
J Exp Med
, vol.188
, pp. 2301-2311
-
-
Azzam, H.S.1
Grinberg, A.2
Lui, K.3
Shen, H.4
Shores, E.W.5
Love, P.E.6
-
22
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998; 273: 13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
23
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki A, de la Pompa JL, Stambolic Elia AJ, Sasaki T, del Barco Barrantes I et al. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr Biol 1998; 8: 1169-1178.
-
(1998)
Curr Biol
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
de la Pompa, J.L.2
Stambolic Elia, A.J.3
Sasaki, T.4
del Barco Barrantes, I.5
-
24
-
-
0032843540
-
Impaired Fas response and autoimmunity in Pten+/-mice
-
Di Cristofano A, Kotsi P, Peng YF, Cordon-Cardo C, Elkon KB, Pandolfi PP. Impaired Fas response and autoimmunity in Pten+/-mice. Science 1999; 285: 2122-2125.
-
(1999)
Science
, vol.285
, pp. 2122-2125
-
-
Di Cristofano, A.1
Kotsi, P.2
Peng, Y.F.3
Cordon-Cardo, C.4
Elkon, K.B.5
Pandolfi, P.P.6
-
25
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006; 441: 475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
-
26
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
Podsypanina K, Ellenson LH, Nemes A, Gu J, Tamura M, Yamada KM et al Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci USA 1999; 96: 1563-1568.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
-
27
-
-
3042801429
-
Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway
-
Uddin S, Hussain A, Al-Hussein K, Platanias LC, Bhatia KG. Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway. Biochem Biophys Res Commun 2004; 320: 932-938.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 932-938
-
-
Uddin, S.1
Hussain, A.2
Al-Hussein, K.3
Platanias, L.C.4
Bhatia, K.G.5
-
28
-
-
5444269438
-
The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling
-
Hagenbeek TJ, Naspetti M, Malergue F, Garcon F, Nunes JA, Cleutjens KB et al. The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling. J Exp Med 2004; 200 883-894.
-
(2004)
J Exp Med
, vol.200
, pp. 883-894
-
-
Hagenbeek, T.J.1
Naspetti, M.2
Malergue, F.3
Garcon, F.4
Nunes, J.A.5
Cleutjens, K.B.6
-
29
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW et al A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001; 15: 763-774.
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
-
30
-
-
0036637660
-
PTEN is essential for cell migration but not for late determination and tumourigenesis in the cerebellum
-
Marino S, Krimpenfort P, Leung C, van der Korput HA, Trapman J, Camenisch I et al. PTEN is essential for cell migration but not for late determination and tumourigenesis in the cerebellum. Development 2002; 129: 3513-3522.
-
(2002)
Development
, vol.129
, pp. 3513-3522
-
-
Marino, S.1
Krimpenfort, P.2
Leung, C.3
van der Korput, H.A.4
Trapman, J.5
Camenisch, I.6
-
31
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994; 265: 103-106.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
32
-
-
0030775139
-
Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
-
Kirberg J, Berns A, von Boehmer H. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J Exp Med 1997; 186: 1269-1275.
-
(1997)
J Exp Med
, vol.186
, pp. 1269-1275
-
-
Kirberg, J.1
Berns, A.2
von Boehmer, H.3
-
33
-
-
10244237695
-
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: Functional inactivation of p53 in developing T cells
-
Gimeno R, Weijer K, Voordouw A, Uittenbogaart CH, Legrand N, Alves NL et al. Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells. Blood 2004; 104: 3886-3893.
-
(2004)
Blood
, vol.104
, pp. 3886-3893
-
-
Gimeno, R.1
Weijer, K.2
Voordouw, A.3
Uittenbogaart, C.H.4
Legrand, N.5
Alves, N.L.6
-
34
-
-
40749131296
-
HTLV-associated T-cell lymphoma and leukemia
-
eds, 4th edn. Cambridge University Press, The Edinburgh Building: Cambridge, UK
-
Wiernik PH. HTLV-associated T-cell lymphoma and leukemia. In: Wiernik PH, Goldman JM, Dutcher JP, Kyle RA (eds). Neoplastic Diseases of the Blood, 4th edn. Cambridge University Press, The Edinburgh Building: Cambridge, UK, 2003, pp 156.
-
(2003)
Neoplastic Diseases of the Blood
, pp. 156
-
-
Wiernik, P.H.1
-
35
-
-
0030966842
-
CD44: Structure, function, and association with the malignant process
-
Naor D, Sionov RV, Ish-Shalom D. CD44: Structure, function, and association with the malignant process. Adv Cancer Res 1997; 71 241-319.
-
(1997)
Adv Cancer Res
, vol.71
, pp. 241-319
-
-
Naor, D.1
Sionov, R.V.2
Ish-Shalom, D.3
-
36
-
-
0033973369
-
The CD44 receptor of lymphoma cells: Structure-function relationships and mechanism of activation
-
Rochman M, Moll J, Herrlich P, Wallach SB, Nedvetzki S, Sionov RV et al. The CD44 receptor of lymphoma cells: Structure-function relationships and mechanism of activation. Cell Adhes Commun 2000; 7: 331-347.
-
(2000)
Cell Adhes Commun
, vol.7
, pp. 331-347
-
-
Rochman, M.1
Moll, J.2
Herrlich, P.3
Wallach, S.B.4
Nedvetzki, S.5
Sionov, R.V.6
-
37
-
-
0029032423
-
Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent
-
Zahalka MA, Okon E, Gosslar U, Holzmann B, Naor D. Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent. J Immunol 1995; 154: 5345-5355.
-
(1995)
J Immunol
, vol.154
, pp. 5345-5355
-
-
Zahalka, M.A.1
Okon, E.2
Gosslar, U.3
Holzmann, B.4
Naor, D.5
-
38
-
-
26944480087
-
Identification of the tumor cells in peripheral T-cell lymphomas by combined polymerase chain reaction-based T-cell receptor beta spectrotyping and immunohistological detection with T-cell receptor beta chain variable region segment-specific antibodies
-
Geissinger E, Bonzheim I, Krenacs L, Roth S, Strobel P, Ott G et al Identification of the tumor cells in peripheral T-cell lymphomas by combined polymerase chain reaction-based T-cell receptor beta spectrotyping and immunohistological detection with T-cell receptor beta chain variable region segment-specific antibodies. J Mol Diagn 2005; 7: 455-464.
-
(2005)
J Mol Diagn
, vol.7
, pp. 455-464
-
-
Geissinger, E.1
Bonzheim, I.2
Krenacs, L.3
Roth, S.4
Strobel, P.5
Ott, G.6
-
39
-
-
0028242609
-
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development
-
Sawada S, Scarborough JD, Killeen N, Littman DR. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 1994; 77: 917-929.
-
(1994)
Cell
, vol.77
, pp. 917-929
-
-
Sawada, S.1
Scarborough, J.D.2
Killeen, N.3
Littman, D.R.4
-
40
-
-
0042847224
-
Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation
-
Na SY, Patra A, Scheuring Y, Marx A, Tolaini M, Kioussis D et al. Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. J Immunol 2003; 171: 1285-1296.
-
(2003)
J Immunol
, vol.171
, pp. 1285-1296
-
-
Na, S.Y.1
Patra, A.2
Scheuring, Y.3
Marx, A.4
Tolaini, M.5
Kioussis, D.6
-
41
-
-
0034107671
-
Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo
-
Borlado LR, Redondo C, Alvarez B, Jimenez C, Criado LM, Flores J et al. Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo. FASEB J 2000; 14: 895-903.
-
(2000)
FASEB J
, vol.14
, pp. 895-903
-
-
Borlado, L.R.1
Redondo, C.2
Alvarez, B.3
Jimenez, C.4
Criado, L.M.5
Flores, J.6
-
42
-
-
23844462453
-
Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase
-
Webb LM, Vigorito E, Wymann MP, Hirsch E, Turner M. Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J Immunol 2005; 175: 2783-2787.
-
(2005)
J Immunol
, vol.175
, pp. 2783-2787
-
-
Webb, L.M.1
Vigorito, E.2
Wymann, M.P.3
Hirsch, E.4
Turner, M.5
-
43
-
-
33644765808
-
Essential role of P13Kdelta and P13Kgamma in thymocyte survival
-
Swat W, Montgrain V, Doggett TA, Douangpanya J, Puri K, Vermi W et al Essential role of P13Kdelta and P13Kgamma in thymocyte survival. Blood 2006; 107: 2415-2422.
-
(2006)
Blood
, vol.107
, pp. 2415-2422
-
-
Swat, W.1
Montgrain, V.2
Doggett, T.A.3
Douangpanya, J.4
Puri, K.5
Vermi, W.6
-
45
-
-
0242416992
-
Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio
-
Rodriguez-Borlado L, Barber DF, Hernandez C, Rodriguez-Marcos MA, Sanchez A, Hirsch E et al. Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio. J Immunol 2003; 170 4475-4482.
-
(2003)
J Immunol
, vol.170
, pp. 4475-4482
-
-
Rodriguez-Borlado, L.1
Barber, D.F.2
Hernandez, C.3
Rodriguez-Marcos, M.A.4
Sanchez, A.5
Hirsch, E.6
-
46
-
-
0035909946
-
Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus
-
Malstrom S, Tili E, Kappes D, Ceci JD, Tsichlis PN. Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus. Proc Natl Acad Sci USA 2001; 98: 14967-14972.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14967-14972
-
-
Malstrom, S.1
Tili, E.2
Kappes, D.3
Ceci, J.D.4
Tsichlis, P.N.5
-
47
-
-
33746154235
-
Genetic background controls tumor development in PTEN-deficient mice
-
Freeman D, Lesche R, Kertesz N, Wang S, Li G, Gao J et al. Genetic background controls tumor development in PTEN-deficient mice. Cancer Res 2006; 66: 6492-6496.
-
(2006)
Cancer Res
, vol.66
, pp. 6492-6496
-
-
Freeman, D.1
Lesche, R.2
Kertesz, N.3
Wang, S.4
Li, G.5
Gao, J.6
-
48
-
-
0141955349
-
PTEN and p53: Who will get tke upper hand?
-
Trotman LC, Pandolfi PP. PTEN and p53: Who will get tke upper hand? Cancer Cell 2003; 3: 97-99.
-
(2003)
Cancer Cell
, vol.3
, pp. 97-99
-
-
Trotman, L.C.1
Pandolfi, P.P.2
-
49
-
-
0034912744
-
PTEN and myotubularin: Novel phosphoinositide phosphatases
-
Maehama T, Taylor GS, Dixon JE. PTEN and myotubularin: Novel phosphoinositide phosphatases. Annu Rev Biochem 2001; 70: 247-279.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 247-279
-
-
Maehama, T.1
Taylor, G.S.2
Dixon, J.E.3
-
50
-
-
23744494993
-
Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells
-
Avellino R, Romano S, Parasole R, Bisogni R, Lamberti A, Poggi V et al. Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells. Blood 2005; 106: 1400-1406.
-
(2005)
Blood
, vol.106
, pp. 1400-1406
-
-
Avellino, R.1
Romano, S.2
Parasole, R.3
Bisogni, R.4
Lamberti, A.5
Poggi, V.6
-
51
-
-
0033637216
-
NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
-
Voll RE, Jimi E, Phillips RJ, Barber DF, Rincon M, Hayday AC et al NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development. Immunity 2000; 13: 677-689.
-
(2000)
Immunity
, vol.13
, pp. 677-689
-
-
Voll, R.E.1
Jimi, E.2
Phillips, R.J.3
Barber, D.F.4
Rincon, M.5
Hayday, A.C.6
-
52
-
-
33846048039
-
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia
-
Vilimas T, Mascarenhas J, Palomero T, Mandal M, Buonamici S, Meng F et al. Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nat Med 2007; 13: 70-77.
-
(2007)
Nat Med
, vol.13
, pp. 70-77
-
-
Vilimas, T.1
Mascarenhas, J.2
Palomero, T.3
Mandal, M.4
Buonamici, S.5
Meng, F.6
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