Benzothiazinones: A novel class of adenosine receptor antagonists structurally unrelated to xanthine and adenine derivatives

Journal of Medicinal Chemistry

Volumn 55, Issue 7, 2012, Pages 3331-3341

  Gütschow, Michael ^a   Schlenk, Miriam ^a   Gäb, Jürgen ^a   Paskaleva, Minka ^a   Alnouri, Mohamad Wessam ^a   Scolari, Silvia ^a   Iqbal, Jamshed ^a,b   Müller, Christa E ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Tobe Camp University Road Abbottabad   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 METHYLBENZOYLAMINO) 4H 3,1 BENZOTHIAZIN 4 ONE; 4 (4 METHYLPIPERAZINE 1 CARBONYL) N (4 OXO 4H 3,1 BENZOTHIAZIN 2 YL)BENZAMIDE; 4 AMINOMETHYL N (4 OXO 4H 3,1 BENZOTHIAZIN 2 YL)BENZAMIDE HYDROCHLORIDE; 6 METHYL 2 [(4 METHYLBENZOYL)AMINO] 4H 3,1 BENZOTHIAZIN 4 ONE; 6 METHYL 2 BENZOYLAMINO 4H 3,1 BENZOTHIAZIN 4 ONE; ADENINE DERIVATIVE; ADENOSINE RECEPTOR BLOCKING AGENT; N (4 OXO 4H 3,1 BENZOTHIAZIN 2 YL) 2 PHENYLACETAMIDE; N (5,6 DIMETHYL 4 OXO 4H THIENO[2,3 D][1,3]THIAZIN 2 YL) BENZAMIDE; N (6 (4 METHYLPIPERAZINE 1 CARBONYL) 4 OXO 4H 3,1 BENZOTHIAZIN 2 YL))BENZAMIDE; N (7 (4 METHYLPIPERAZINE 1 CARBONYL) 4 OXO 4H 3,1 BENZOTHIAZIN 2 YL))BENZAMIDE; RADIOLIGAND; TERT BUTYL (4 OXO 4H 3,1 BENZOTHIAZIN 2 YLCARBAMOYL) BENZYLCARBAMATE; THIAZINE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHO CELL; CYCLOCONDENSATION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; PURINERGIC P1 RECEPTOR AGONISTS; PURINERGIC P1 RECEPTOR ANTAGONISTS; RADIOLIGAND ASSAY; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES; THIOPHENES;

EID: 84859791349     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300029s     Document Type: Article

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