Inhibition of cathepsin G by 4H-3,1-benzoxazin-4-ones

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 10, 1997, Pages 1935-1942

  Gütschow, Michael ^a   Neumann, Uf ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 BENZYLUREIDO)BENZOIC ACID; 2 BENZYLAMINO 4H 3,1 BENZOXAZIN 4 ONE; 3 BENZYLQUINAZOLINE 2,4 (1H,3H) DIONE; 4H 3,1 BENZOXAZIN 4 ONE DERIVATIVE; CATHEPSIN G; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME DEGRADATION; INHIBITION KINETICS; PROTEINASE INHIBITION;

ANIMALS; CATHEPSINS; CATTLE; CHYMOTRYPSIN; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OXAZINES; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

BOVINAE;

EID: 0342276109     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00128-4     Document Type: Article

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